Development toward rapid and efficient screening for high performance hydrolysate lots in a recombinant monoclonal antibody manufacturing process

Biotechnology Progress

Volumn 28, Issue 4, 2012, Pages 1061-1068

  Luo, Ying ^a   Pierce, Karisa M ^b  

^a AMGEN INC   (United States)

^b SEATTLE PACIFIC UNIVERSITY   (United States)

Author keywords

Hydrolysate; Nuclear magnetic resonance spectroscopy; Partial least squares predictive modeling; Peptone; Screening; Soy; Titer

Indexed keywords

HYDROLYSATE; PEPTONE; PREDICTIVE MODELING; SOY; TITER;

CELL CULTURE; INDUSTRIAL ENGINEERING; LACTIC ACID; MONOCLONAL ANTIBODIES; PRODUCTION ENGINEERING; QUALITY CONTROL; RECOMBINANT PROTEINS; SCREENING; SUGARS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

MONOCLONAL ANTIBODY; PROTEIN HYDROLYSATE; RECOMBINANT PROTEIN; SOYBEAN PROTEIN;

ARTICLE; BIOREACTOR; BIOTECHNOLOGY; CHEMISTRY; CULTURE MEDIUM; CULTURE TECHNIQUE; GENETICS; INSTRUMENTATION; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANTIBODIES, MONOCLONAL; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CULTURE MEDIA; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN HYDROLYSATES; RECOMBINANT PROTEINS; SOYBEAN PROTEINS;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 84864835423     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1568     Document Type: Article

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