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Volumn 107, Issue 1, 2010, Pages 182-189

A study of D-lactate and extracellular methylglyoxal production in lactate re-utilizing CHO cultures

Author keywords

CHO; D lactate; Lactate re utilization; MAb production; Methylglyoxal

Indexed keywords

CHO; D-LACTATE; MAB PRODUCTION; METHYLGLYOXAL; RE-UTILIZATION;

EID: 77956241143     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22757     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 0014063788 scopus 로고
    • 14 C in the rat
    • 14 C in the rat. J Nutr 91:399-406.
    • (1967) J Nutr , vol.91 , pp. 399-406
    • Baum, V.C.1
  • 2
    • 0028322028 scopus 로고
    • Biochemical genetics of methylglyoxal reductase in the laboratory rat (Rattus norvegicus)
    • Bender K, Seibert RT, Weinker TF, Kren V, Pravenec M, Bissbort S. 1994. Biochemical genetics of methylglyoxal reductase in the laboratory rat (Rattus norvegicus). Biochem Gen 32:147-154.
    • (1994) Biochem Gen , vol.32 , pp. 147-154
    • Bender, K.1    Seibert, R.T.2    Weinker, T.F.3    Kren, V.4    Pravenec, M.5    Bissbort, S.6
  • 3
    • 35548990601 scopus 로고    scopus 로고
    • Selection methods for high-producing mammalian cell lines
    • Browne SM, Al-Rubeai M. 2007. Selection methods for high-producing mammalian cell lines. Trends Biotechnol 25:425-432.
    • (2007) Trends Biotechnol , vol.25 , pp. 425-432
    • Browne, S.M.1    Al-Rubeai, M.2
  • 4
    • 0028989413 scopus 로고
    • Nutrient enrichment and in-situ waste removal through electrical means for hybridoma cultures
    • Chang Y, Grodzinsky A, Wang D. 1995. Nutrient enrichment and in-situ waste removal through electrical means for hybridoma cultures. Biotech Bioeng 47:319-326.
    • (1995) Biotech Bioeng , vol.47 , pp. 319-326
    • Chang, Y.1    Grodzinsky, A.2    Wang, D.3
  • 5
    • 0031900403 scopus 로고    scopus 로고
    • Incidence and potential implications of the toxic metabolite methylglyoxal in cell culture: A review
    • Chaplen FR. 1998. Incidence and potential implications of the toxic metabolite methylglyoxal in cell culture: A review. Cytotechnology 26:173-183.
    • (1998) Cytotechnology , vol.26 , pp. 173-183
    • Chaplen, F.R.1
  • 6
    • 0030200936 scopus 로고    scopus 로고
    • Method for the determination of free intracellular and extracellular methylglyoxal in animal cells grown in culture
    • Chaplen FR, Fahl WE, Cameron DC. 1996. Method for the determination of free intracellular and extracellular methylglyoxal in animal cells grown in culture. Anal Biochem 238:171-178.
    • (1996) Anal Biochem , vol.238 , pp. 171-178
    • Chaplen, F.R.1    Fahl, W.E.2    Cameron, D.C.3
  • 7
    • 24344466271 scopus 로고    scopus 로고
    • Production of recombinant therapeutic proteins by mammalian cells in suspension culture. Methods in molecular biology series
    • Humana Press: New York
    • Chu L, Blumentals I, Maheshwari G. 2005. Production of recombinant therapeutic proteins by mammalian cells in suspension culture. Methods in molecular biology series. Therapeutic Proteins. Humana Press: New York, pp. 107-121.
    • (2005) Therapeutic Proteins , pp. 107-121
    • Chu, L.1    Blumentals, I.2    Maheshwari, G.3
  • 9
    • 0025465346 scopus 로고
    • The effect of pH on the toxicity of ammonia to a murine hybridoma
    • Doyle C, Butler M. 1990. The effect of pH on the toxicity of ammonia to a murine hybridoma. J Biotechnol 15(1-2):91-100.
    • (1990) J Biotechnol , vol.15 , Issue.1-2 , pp. 91-100
    • Doyle, C.1    Butler, M.2
  • 10
    • 0026219281 scopus 로고
    • Factors controlling cell proliferation and antibody production in mouse hybridoma cells: Influence of the amino acid supply
    • Duval D, Demangel C, Munier-Jolain K, Miossec S, Geahel I. 1991. Factors controlling cell proliferation and antibody production in mouse hybridoma cells: Influence of the amino acid supply. Biotech Bioeng 38:561-570.
    • (1991) Biotech Bioeng , vol.38 , pp. 561-570
    • Duval, D.1    Demangel, C.2    Munier-Jolain, K.3    Miossec, S.4    Geahel, I.5
  • 11
    • 34247151553 scopus 로고    scopus 로고
    • Improvement of the energy metabolism of recombinant CHO cells by cell sorting for reduced mitochondrial membrane potential
    • Hinterkörner G, Brugger G, Müller D, Hesse F, Kunert R, Katinger H, Borth N. 2007. Improvement of the energy metabolism of recombinant CHO cells by cell sorting for reduced mitochondrial membrane potential. J Biotechnol 129(4):651-657.
    • (2007) J Biotechnol , vol.129 , Issue.4 , pp. 651-657
    • Hinterkörner, G.1    Brugger, G.2    Müller, D.3    Hesse, F.4    Kunert, R.5    Katinger, H.6    Borth, N.7
  • 12
    • 0028853680 scopus 로고
    • Methylglyoxal and regulation of its metabolism in microorganisms
    • Inoue Y, Kimura A. 1995. Methylglyoxal and regulation of its metabolism in microorganisms. Adv Microbial Phys 37:177-227.
    • (1995) Adv Microbial Phys , vol.37 , pp. 177-227
    • Inoue, Y.1    Kimura, A.2
  • 13
    • 0032703938 scopus 로고    scopus 로고
    • Methglyoxal in living organisms; chemistry, biochemistry, toxicology and biological implications
    • Kalapos MP. 1999. Methglyoxal in living organisms; chemistry, biochemistry, toxicology and biological implications. Toxicol Lett 110:145-175.
    • (1999) Toxicol Lett , vol.110 , pp. 145-175
    • Kalapos, M.P.1
  • 14
    • 84988106827 scopus 로고
    • A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: Effect of nutrient concentration, dilution rate, and pH
    • Miller WM, Blanch HW, Wilke CR. 1987. A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: Effect of nutrient concentration, dilution rate, and pH. Biotech Bioeng 32:947-965.
    • (1987) Biotech Bioeng , vol.32 , pp. 947-965
    • Miller, W.M.1    Blanch, H.W.2    Wilke, C.R.3
  • 15
    • 33747343749 scopus 로고    scopus 로고
    • Reactor engineering in large scale animal cell culture
    • Nienow A. 2006. Reactor engineering in large scale animal cell culture. Cytotechnology 50:9-33.
    • (2006) Cytotechnology , vol.50 , pp. 9-33
    • Nienow, A.1
  • 16
    • 0027112176 scopus 로고
    • Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation
    • Omasa T, Higashiyama K, Shioya S, Suga K. 1991. Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation. Biotech Bioeng 39:556-564.
    • (1991) Biotech Bioeng , vol.39 , pp. 556-564
    • Omasa, T.1    Higashiyama, K.2    Shioya, S.3    Suga, K.4
  • 17
    • 28444483135 scopus 로고    scopus 로고
    • Toxic concentrations of exogenously supplied methylglyoxal in hybridoma cell culture
    • Roy BM, Rau TD, Balcarcel BB. 2005. Toxic concentrations of exogenously supplied methylglyoxal in hybridoma cell culture. Cytotechnology 46:97-107.
    • (2005) Cytotechnology , vol.46 , pp. 97-107
    • Roy, B.M.1    Rau, T.D.2    Balcarcel, B.B.3
  • 18
    • 0025298551 scopus 로고
    • The glyoxylase system: New developments towards functional characterisation of a metabolic pathway fundamental to biological life
    • Thornalley PJ. 1990. The glyoxylase system: New developments towards functional characterisation of a metabolic pathway fundamental to biological life. Biochem J 269:1-11.
    • (1990) Biochem J , vol.269 , pp. 1-11
    • Thornalley, P.J.1
  • 19
    • 0027454552 scopus 로고
    • The glyoxylase system in health and disease
    • Thornalley PJ. 1993. The glyoxylase system in health and disease. Mol Aspects Med 14:287-371.
    • (1993) Mol Aspects Med , vol.14 , pp. 287-371
    • Thornalley, P.J.1
  • 20
    • 0029005896 scopus 로고
    • Advances in glyoxylase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxylase I inhibitior diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced glycation endproduct receptor
    • Thornalley PJ. 1995. Advances in glyoxylase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxylase I inhibitior diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced glycation endproduct receptor. Crit Rev Oncol Hematol 20:99-128.
    • (1995) Crit Rev Oncol Hematol , vol.20 , pp. 99-128
    • Thornalley, P.J.1
  • 21
    • 0030176306 scopus 로고    scopus 로고
    • Pharmacology of methylglyoxal: Formation, modification of proteins and nucleic acids and enzymatic detoxification - A role in parthogenesis and antiproliferative chemotherapy
    • Thornalley PJ. 1996. Pharmacology of methylglyoxal: Formation, modification of proteins and nucleic acids and enzymatic detoxification - A role in parthogenesis and antiproliferative chemotherapy. Gen Pharma 27(4):565-573.
    • (1996) Gen Pharma , vol.27 , Issue.4 , pp. 565-573
    • Thornalley, P.J.1
  • 22
    • 0020350371 scopus 로고
    • 2-ketoaldehyde dehydrogenase from rat liver
    • Vander Jagt DL. 1982. 2-ketoaldehyde dehydrogenase from rat liver. Methods Enzymol 89:513-515.
    • (1982) Methods Enzymol , vol.89 , pp. 513-515
    • Vander Jagt, D.L.1
  • 24
    • 8344271026 scopus 로고    scopus 로고
    • Production of recombinant protein therapeutics in cultivated mammalian cells
    • Wurm FM. 2004. Production of recombinant protein therapeutics in cultivated mammalian cells. Nature 22(11):1393-1398.
    • (2004) Nature , vol.22 , Issue.11 , pp. 1393-1398
    • Wurm, F.M.1
  • 25
    • 0028436953 scopus 로고
    • Stoichiometric analysis of animal cell growth and its application in medium design
    • Xie L, Wang D. 1993. Stoichiometric analysis of animal cell growth and its application in medium design. Biotech Bioeng 43:1164-1174.
    • (1993) Biotech Bioeng , vol.43 , pp. 1164-1174
    • Xie, L.1    Wang, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.