Combined approach of NMR and chemometrics for screening peptones used in the cell culture medium for the production of a recombinant therapeutic protein

Biotechnology and Bioengineering

Volumn 97, Issue 6, 2007, Pages 1654-1659

  Luo, Ying ^a   Chen, Guoxiang ^a  

^a AMGEN INC   (United States)

Author keywords

Cell culture medium; Chemometrics; NMR; Peptone

Indexed keywords

CELL CULTURE; CHEMOSTATS; NUCLEAR MAGNETIC RESONANCE; PROTEINS;

CELL CULTURE MEDIUM; CHEMOMETRICS; PEPTONES; THERAPEUTIC RECOMBINANT PROTEINS;

KETONES;

PEPTONE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CHEMOMETRICS; CONTROLLED STUDY; CULTURE MEDIUM; FEASIBILITY STUDY; LARGE SCALE PRODUCTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; CELL CULTURE TECHNIQUES; CHO CELLS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRICETINAE; CRICETULUS; CULTURE MEDIA; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE MAPPING; PEPTONES; RECOMBINANT PROTEINS;

EID: 34547637286     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21365     Document Type: Article

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