"Snorkeling" for missing players in cancer

Journal of Clinical Investigation

Volumn 122, Issue 8, 2012, Pages 2765-2768

  Taulli, Riccardo ^a,b   Pandolfi, Pier Paolo ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; SMALL NUCLEOLAR RNA;

CHROMOSOME TRANSLOCATION; GENE; HUMAN; MULTIPLE MYELOMA; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; WHSC1 GENE;

EID: 84864776526     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI63549     Document Type: Note

References (23)

1. Guttman M, Rinn JL. Modular regulatory principles of large non-coding RNAs. Nature. 2012;482(7385):339-346.
2. Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell. 2011;146(3):353-358.
3. Bratkovic T, Rogelj B. Biology and applications of small nucleolar RNAs. Cell Mol Life Sci. 2011;68(23):3843-3851.
4. Matera AG, Terns RM, Terns MP. Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev Mol Cell Biol. 2007;8(3):209-220.
5. Chu L, et al. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. J Clin Invest. 2012;122(8):2793-2806.
6. Palumbo A, Anderson KN. Multiple myeloma. N Engl J Med. 2011;364(11):1046-1060.
7. Chesi M, Nardini E, Lim RS, Smith KD, Kuehl WM, Bergsagel PL. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood. 1998;92(9):3025-3034. (Pubitemid 28492306)
8. Hoeppner MP, White S, Jeffares DC, Poole AM. Evolutionarily stable association of intronic snoRNAs and microRNAs with their host genes. Genome Biol Evol. 2009;1:420-428.
9. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-233.
10. Williams GT, Farzaneh F. Are snoRNAs and snoRNA host genes new players in cancer? Nat Rev Cancer. 2012;12(2):84-88.
11. Dong XY, et al. Implication of snoRNA U50 in human breast cancer. J Genet Genomics. 2009;36(8):447-454.
12. Martens-Uzunova ES, et al. Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer. Oncogene. 2012;31(8):978-991.
13. Smith CM, Steitz JA. Classification of gas5 as a multi-small-nucleolar- RNA (snoRNA) host gene and a member of the 5′-terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol. 1998;18(12):6897-6909. (Pubitemid 28533011)
14. Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP. Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal. 2010;3(107):ra8.
15. Lauring J, et al. The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity. Blood. 2008;111(2):856-864.
16. Michel CI, et al. Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress. Cell Metab. 2011;14(1):33-44.
17. Ender C, et al. A human snoRNA with microRNA-like functions. Mol Cell. 2008;32(4):519-528.
18. Karreth FA, et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell. 2011;147(2):382-395.
19. Tay Y, et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell. 2011;147(2):344-357.
20. Cesana M, et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell. 2011;147(2):358-369.
21. Sumazin P, et al. An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell. 2011;147(2):370-381.
22. Cazalla D, Yario T, Steitz JA. Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. Science. 2010;328(5985):1563-1566.
23. Obad S, et al. Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet. 2011;43(4):371-378.