메뉴 건너뛰기




Volumn 303, Issue 3, 2012, Pages

Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro

Author keywords

25 hydroxycholesterol; Liver proliferation; Liver X Receptors; Oxysterol; Proliferating cell nuclear antigen

Indexed keywords

CYCLINE; ISOENZYME; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; OXYSTEROL; SMALL INTERFERING RNA; SULFOTRANSFERASE; SULFOTRANSFERASE 2B1B; UNCLASSIFIED DRUG;

EID: 84864747561     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00403.2011     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 79151476474 scopus 로고    scopus 로고
    • Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells
    • Bai Q, Xu L, Kakiyama G, Runge-Morris MA, Hylemon PB, Yin L, Pandak WM, Ren S. Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. Atherosclerosis 214: 350-356, 2011.
    • (2011) Atherosclerosis , vol.214 , pp. 350-356
    • Bai, Q.1    Xu, L.2    Kakiyama, G.3    Runge-Morris, M.A.4    Hylemon, P.B.5    Yin, L.6    Pandak, W.M.7    Ren, S.8
  • 3
    • 0036736781 scopus 로고    scopus 로고
    • Do oxysterols control cholesterol homeostasis?
    • Bjorkhem I. Do oxysterols control cholesterol homeostasis? J Clin Invest 110: 725-730, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 725-730
    • Bjorkhem, I.1
  • 5
    • 0028843657 scopus 로고
    • Effect of oxysterol treatment on cholesterol biosynthesis and reactive astrocyte proliferation in injured rat brain cortex
    • Bochelen D, Mersel M, Behr P, Lutz P, Kupferberg A. Effect of oxysterol treatment on cholesterol biosynthesis and reactive astrocyte proliferation in injured rat brain cortex. J Neurochem 65: 2194-2200, 1995.
    • (1995) J Neurochem , vol.65 , pp. 2194-2200
    • Bochelen, D.1    Mersel, M.2    Behr, P.3    Lutz, P.4    Kupferberg, A.5
  • 6
    • 3843061127 scopus 로고    scopus 로고
    • Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
    • Chen G, Liang G, Ou J, Goldstein JL, Brown MS. Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci USA 101: 11245-11250, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11245-11250
    • Chen, G.1    Liang, G.2    Ou, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 7
    • 33845587711 scopus 로고    scopus 로고
    • Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
    • Chen W, Chen G, Head DL, Mangelsdorf DJ, Russell DW. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab 5: 73-79, 2007.
    • (2007) Cell Metab , vol.5 , pp. 73-79
    • Chen, W.1    Chen, G.2    Head, D.L.3    Mangelsdorf, D.J.4    Russell, D.W.5
  • 8
    • 80052731804 scopus 로고    scopus 로고
    • Influenza A virus infection activates cholesterol sulfotransferase (SULT2B1b) in the lung of female C57BL/6 mice
    • Chen Y, Chen X, Zhang S, Chen G. Influenza A virus infection activates cholesterol sulfotransferase (SULT2B1b) in the lung of female C57BL/6 mice. Biol Chem 392: 869-876, 2011.
    • (2011) Biol Chem , vol.392 , pp. 869-876
    • Chen, Y.1    Chen, X.2    Zhang, S.3    Chen, G.4
  • 9
    • 34249682775 scopus 로고    scopus 로고
    • Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: Liver X receptor-mediated lipotoxicity in pancreatic beta-cells
    • Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, Lee KM, Park KG, Lee IK, Kim JB. Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells. Diabetes 56: 1534-1543, 2007.
    • (2007) Diabetes , vol.56 , pp. 1534-1543
    • Choe, S.S.1    Choi, A.H.2    Lee, J.W.3    Kim, K.H.4    Chung, J.J.5    Park, J.6    Lee, K.M.7    Park, K.G.8    Lee, I.K.9    Kim, J.B.10
  • 11
    • 16844385404 scopus 로고    scopus 로고
    • Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice
    • Chuu CP, Hiipakka RA, Fukuchi J, Kokontis JM, Liao S. Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice. Cancer Res 65: 2082-2084, 2005.
    • (2005) Cancer Res , vol.65 , pp. 2082-2084
    • Chuu, C.P.1    Hiipakka, R.A.2    Fukuchi, J.3    Kokontis, J.M.4    Liao, S.5
  • 12
    • 70349280717 scopus 로고    scopus 로고
    • 24-Hydroxycholesterol sulfation by human cytosolic sulfotransferases: Formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver X receptor activation
    • Cook IT, Duniec-Dmuchowski Z, Kocarek TA, Runge-Morris M, Falany CN. 24-Hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver X receptor activation. Drug Metab Dispos 37: 2069-2078, 2009.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2069-2078
    • Cook, I.T.1    Duniec-Dmuchowski, Z.2    Kocarek, T.A.3    Runge-Morris, M.4    Falany, C.N.5
  • 13
    • 0032549065 scopus 로고    scopus 로고
    • Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases
    • Coughtrie MW, Sharp S, Maxwell K, Innes NP. Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases. Chem Biol Interact 109: 3-27, 1998.
    • (1998) Chem Biol Interact , vol.109 , pp. 3-27
    • Coughtrie, M.W.1    Sharp, S.2    Maxwell, K.3    Innes, N.P.4
  • 14
    • 0030996250 scopus 로고    scopus 로고
    • Enzymology of human cytosolic sulfotransferases
    • Falany CN. Enzymology of human cytosolic sulfotransferases. FASEB J 11: 206-216, 1997.
    • (1997) FASEB J , vol.11 , pp. 206-216
    • Falany, C.N.1
  • 15
    • 33751015135 scopus 로고    scopus 로고
    • Human cytosolic sulfotransferase 2B1: Isoform expression, tissue specificity and subcellular localization
    • Falany CN, He D, Dumas N, Frost AR, Falany JL. Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization. J Steroid Biochem Mol Biol 102: 214-221, 2006.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 214-221
    • Falany, C.N.1    He, D.2    Dumas, N.3    Frost, A.R.4    Falany, J.L.5
  • 17
    • 0037184096 scopus 로고    scopus 로고
    • Mutational analysis of human hydroxysteroid sulfotransferase SULT2B1 isoforms reveals that exon 1B of the SULT2B1 gene produces cholesterol sulfotransferase, whereas exon 1A yields pregnenolone sulfotransferase
    • Fuda H, Lee YC, Shimizu C, Javitt NB, Strott CA. Mutational analysis of human hydroxysteroid sulfotransferase SULT2B1 isoforms reveals that exon 1B of the SULT2B1 gene produces cholesterol sulfotransferase, whereas exon 1A yields pregnenolone sulfotransferase. J Biol Chem 277: 36161-36166, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 36161-36166
    • Fuda, H.1    Lee, Y.C.2    Shimizu, C.3    Javitt, N.B.4    Strott, C.A.5
  • 18
    • 7444259771 scopus 로고    scopus 로고
    • Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells
    • Fukuchi J, Kokontis JM, Hiipakka RA, Chuu CP, Liao S. Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells. Cancer Res 64: 7686-7689, 2004.
    • (2004) Cancer Res , vol.64 , pp. 7686-7689
    • Fukuchi, J.1    Kokontis, J.M.2    Hiipakka, R.A.3    Chuu, C.P.4    Liao, S.5
  • 21
    • 20444397024 scopus 로고    scopus 로고
    • Identification and immunohistochemical localization of sulfotransferase 2B1b (SULT2B1b) in human lung
    • He D, Frost AR, Falany CN. Identification and immunohistochemical localization of sulfotransferase 2B1b (SULT2B1b) in human lung. Biochim Biophys Acta 1724: 119-126, 2005.
    • (2005) Biochim Biophys Acta , vol.1724 , pp. 119-126
    • He, D.1    Frost, A.R.2    Falany, C.N.3
  • 22
    • 2542597642 scopus 로고    scopus 로고
    • Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate
    • He D, Meloche CA, Dumas NA, Frost AR, Falany CN. Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate. Biochem J 379: 533-540, 2004.
    • (2004) Biochem J , vol.379 , pp. 533-540
    • He, D.1    Meloche, C.A.2    Dumas, N.A.3    Frost, A.R.4    Falany, C.N.5
  • 24
    • 2442421716 scopus 로고    scopus 로고
    • Expression of cholesterol sulfotransferase (SULT2B1b) in human skin and primary cultures of human epidermal keratinocytes
    • Higashi Y, Fuda H, Yanai H, Lee Y, Fukushige T, Kanzaki T, Strott CA. Expression of cholesterol sulfotransferase (SULT2B1b) in human skin and primary cultures of human epidermal keratinocytes. J Invest Dermatol 122: 1207-1213, 2004.
    • (2004) J Invest Dermatol , vol.122 , pp. 1207-1213
    • Higashi, Y.1    Fuda, H.2    Yanai, H.3    Lee, Y.4    Fukushige, T.5    Kanzaki, T.6    Strott, C.A.7
  • 25
    • 0026794030 scopus 로고
    • Hormonal regulation of cholesterol 7β-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures
    • Hylemon PB, Gurley EC, Stravitz RT, Litz JS, Pandak WM, Chiang JY, Vlahcevic ZR. Hormonal regulation of cholesterol 7β-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures. J Biol Chem 267: 16866-16871, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 16866-16871
    • Hylemon, P.B.1    Gurley, E.C.2    Stravitz, R.T.3    Litz, J.S.4    Pandak, W.M.5    Chiang, J.Y.6    Vlahcevic, Z.R.7
  • 27
    • 0034991507 scopus 로고    scopus 로고
    • Cholesterol and hydroxycholesterol sulfotransferases: Identification, distinction from dehydroepiandrosterone sulfotransferase, and differential tissue expression
    • Javitt NB, Lee YC, Shimizu C, Fuda H, Strott CA. Cholesterol and hydroxycholesterol sulfotransferases: identification, distinction from dehydroepiandrosterone sulfotransferase, and differential tissue expression. Endocrinology 142: 2978-2984, 2001.
    • (2001) Endocrinology , vol.142 , pp. 2978-2984
    • Javitt, N.B.1    Lee, Y.C.2    Shimizu, C.3    Fuda, H.4    Strott, C.A.5
  • 29
    • 78650043469 scopus 로고    scopus 로고
    • Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity
    • Kim KH, Lee GY, Kim JI, Ham M, Won Lee J, Kim JB. Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity. J Lipid Res 51: 3425-3433, 2010.
    • (2010) J Lipid Res , vol.51 , pp. 3425-3433
    • Kim, K.H.1    Lee, G.Y.2    Kim, J.I.3    Ham, M.4    Won Lee, J.5    Kim, J.B.6
  • 30
    • 0026701339 scopus 로고
    • Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner
    • Lees E, Faha B, Dulic V, Reed SI, Harlow E. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes Dev 6: 1874-1885, 1992.
    • (1992) Genes Dev , vol.6 , pp. 1874-1885
    • Lees, E.1    Faha, B.2    Dulic, V.3    Reed, S.I.4    Harlow, E.5
  • 31
    • 37249016419 scopus 로고    scopus 로고
    • Biosynthesis of the regulatory oxysterol, 5-cholesten-3+,25-diol 3-sulfate, in hepatocytes
    • Li X, Pandak WM, Erickson SK, Ma Y, Yin L, Hylemon P, Ren S. Biosynthesis of the regulatory oxysterol, 5-cholesten-3+,25-diol 3-sulfate, in hepatocytes. J Lipid Res 48: 2587-2596, 2007.
    • (2007) J Lipid Res , vol.48 , pp. 2587-2596
    • Li, X.1    Pandak, W.M.2    Erickson, S.K.3    Ma, Y.4    Yin, L.5    Hylemon, P.6    Ren, S.7
  • 32
    • 0037088683 scopus 로고    scopus 로고
    • Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory elementbinding protein-1c
    • Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory elementbinding protein-1c. J Biol Chem 277: 9520-9528, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 9520-9528
    • Liang, G.1    Yang, J.2    Horton, J.D.3    Hammer, R.E.4    Goldstein, J.L.5    Brown, M.S.6
  • 35
    • 38749138122 scopus 로고    scopus 로고
    • Sulfotransferase forms expressed in human intestinal Caco-2 and TC7 cells at varying stages of differentiation and role in benzo[a]pyrene metabolism
    • Meinl W, Ebert B, Glatt H, Lampen A. Sulfotransferase forms expressed in human intestinal Caco-2 and TC7 cells at varying stages of differentiation and role in benzo[a]pyrene metabolism. Drug Metab Dispos 36: 276-283, 2008.
    • (2008) Drug Metab Dispos , vol.36 , pp. 276-283
    • Meinl, W.1    Ebert, B.2    Glatt, H.3    Lampen, A.4
  • 36
    • 0034895787 scopus 로고    scopus 로고
    • Expression and characterization of the human 3β-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b)
    • Meloche CA, Falany CN. Expression and characterization of the human 3β-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b). J Steroid Biochem Mol Biol 77: 261-269, 2001.
    • (2001) J Steroid Biochem Mol Biol , vol.77 , pp. 261-269
    • Meloche, C.A.1    Falany, C.N.2
  • 38
    • 40749148846 scopus 로고    scopus 로고
    • Liver X receptors as therapeutic targets in metabolism and atherosclerosis
    • Nomiyama T, Bruemmer D. Liver X receptors as therapeutic targets in metabolism and atherosclerosis. Curr Atheroscler Rep 10: 88-95, 2008.
    • (2008) Curr Atheroscler Rep , vol.10 , pp. 88-95
    • Nomiyama, T.1    Bruemmer, D.2
  • 39
    • 0033504017 scopus 로고    scopus 로고
    • Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations
    • O'Callaghan YC, Woods JA, O'Brien NM. Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations. Eur J Nutr 38: 255-262, 1999.
    • (1999) Eur J Nutr , vol.38 , pp. 255-262
    • O'Callaghan, Y.C.1    Woods, J.A.2    O'Brien, N.M.3
  • 41
    • 21644452252 scopus 로고    scopus 로고
    • Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis
    • Ren S, Hylemon P, Marques D, Hall E, Redford K, Gil G, Pandak WM. Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis. J Lipid Res 45: 2123-2131, 2004.
    • (2004) J Lipid Res , vol.45 , pp. 2123-2131
    • Ren, S.1    Hylemon, P.2    Marques, D.3    Hall, E.4    Redford, K.5    Gil, G.6    Pandak, W.M.7
  • 43
    • 0037387277 scopus 로고    scopus 로고
    • Conservation of the hydroxysteroid sulfotransferase SULT2B1 gene structure in the mouse: Pre-and postnatal expression, kinetic analysis of isoforms, and comparison with prototypical SULT2A1
    • Shimizu C, Fuda H, Yanai H, Strott CA. Conservation of the hydroxysteroid sulfotransferase SULT2B1 gene structure in the mouse: pre-and postnatal expression, kinetic analysis of isoforms, and comparison with prototypical SULT2A1. Endocrinology 144: 1186-1193, 2003.
    • (2003) Endocrinology , vol.144 , pp. 1186-1193
    • Shimizu, C.1    Fuda, H.2    Yanai, H.3    Strott, C.A.4
  • 44
    • 0036796816 scopus 로고    scopus 로고
    • Sulfonation and molecular action
    • Strott CA. Sulfonation and molecular action. Endocr Rev 23: 703-732, 2002.
    • (2002) Endocr Rev , vol.23 , pp. 703-732
    • Strott, C.A.1
  • 45
    • 33845586243 scopus 로고    scopus 로고
    • The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
    • Talukdar S, Hillgartner FB. The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317. J Lipid Res 47: 2451-2461, 2006.
    • (2006) J Lipid Res , vol.47 , pp. 2451-2461
    • Talukdar, S.1    Hillgartner, F.B.2
  • 47
    • 80051978038 scopus 로고    scopus 로고
    • A novel herbal formulation "LiverCare" differentially regulates primary rat hepatocyte and hepatocarcinoma cell proliferation in vitro
    • Vidyashankar S, Varma SR, Azeemudin M, Godavarthi A, Krishna NS, Patki PS. A novel herbal formulation "LiverCare" differentially regulates primary rat hepatocyte and hepatocarcinoma cell proliferation in vitro. J Med Food 14: 1023-1031, 2011.
    • (2011) J Med Food , vol.14 , pp. 1023-1031
    • Vidyashankar, S.1    Varma, S.R.2    Azeemudin, M.3    Godavarthi, A.4    Krishna, N.S.5    Patki, P.S.6
  • 48
    • 0037113939 scopus 로고    scopus 로고
    • Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression
    • Wang X, Krupczak-Hollis K, Tan Y, Dennewitz MB, Adami GR, Costa RH. Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression. J Biol Chem 277: 44310-44316, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 44310-44316
    • Wang, X.1    Krupczak-Hollis, K.2    Tan, Y.3    Dennewitz, M.B.4    Adami, G.R.5    Costa, R.H.6
  • 49
    • 0346727394 scopus 로고    scopus 로고
    • Expression of cholesterol sulfotransferase (SULT2B1b) in human platelets
    • Yanai H, Javitt NB, Higashi Y, Fuda H, Strott CA. Expression of cholesterol sulfotransferase (SULT2B1b) in human platelets. Circulation 109: 92-96, 2004.
    • (2004) Circulation , vol.109 , pp. 92-96
    • Yanai, H.1    Javitt, N.B.2    Higashi, Y.3    Fuda, H.4    Strott, C.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.