메뉴 건너뛰기




Volumn 357, Issue 2, 2007, Pages 341-346

The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells

Author keywords

Androgen; Antiandrogen; AR; LNCaP; LXR agonist; PSA; T0901317

Indexed keywords

ANDROGEN RECEPTOR; ANTIANDROGEN; BICALUTAMIDE; HYDROXYFLUTAMIDE; METRIBOLONE; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; PROSTATE SPECIFIC ANTIGEN;

EID: 34247153122     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.03.116     Document Type: Article
Times cited : (45)

References (38)
  • 1
    • 0028117755 scopus 로고
    • Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors
    • Song C., Kokontis J.M., Hiipakka R.A., and Liao S. Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors. Proc. Natl. Acad. Sci. USA 91 (1994) 10809-10813
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10809-10813
    • Song, C.1    Kokontis, J.M.2    Hiipakka, R.A.3    Liao, S.4
  • 2
    • 0028059845 scopus 로고
    • NER, a new member of the gene family encoding the human steroid hormone nuclear receptor
    • Shinar D.M., Endo N., Rutledge S.J., Vogel R., Rodan G.A., and Schmidt A. NER, a new member of the gene family encoding the human steroid hormone nuclear receptor. Gene 147 (1994) 273-276
    • (1994) Gene , vol.147 , pp. 273-276
    • Shinar, D.M.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Rodan, G.A.5    Schmidt, A.6
  • 3
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski B.A., Willy P.J., Devi T.R., Falck J.R., and Mangelsdorf D.J. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383 (1996) 728-731
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 4
    • 0030885520 scopus 로고    scopus 로고
    • The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism
    • Forman B.M., Ruan B., Chen J., Schroepfer Jr. G.J., and Evans R.M. The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. Proc. Natl. Acad. Sci. USA 94 (1997) 10588-10593
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10588-10593
    • Forman, B.M.1    Ruan, B.2    Chen, J.3    Schroepfer Jr., G.J.4    Evans, R.M.5
  • 6
    • 0033714093 scopus 로고    scopus 로고
    • Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha
    • Song C., and Liao S. Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha. Endocrinology 141 (2000) 4180-4184
    • (2000) Endocrinology , vol.141 , pp. 4180-4184
    • Song, C.1    Liao, S.2
  • 10
    • 0037432165 scopus 로고    scopus 로고
    • T0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice
    • Terasaka N., Hiroshima A., Koieyama T., Ubukata N., Morikawa Y., Nakai D., and Inaba T. T0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Lett. 536 (2003) 6-11
    • (2003) FEBS Lett. , vol.536 , pp. 6-11
    • Terasaka, N.1    Hiroshima, A.2    Koieyama, T.3    Ubukata, N.4    Morikawa, Y.5    Nakai, D.6    Inaba, T.7
  • 12
    • 9444296497 scopus 로고    scopus 로고
    • Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells
    • Efanov A.M., Sewing S., Bokvist K., and Gromada J. Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells. Diabetes 53 (2004) S75-S78
    • (2004) Diabetes , vol.53
    • Efanov, A.M.1    Sewing, S.2    Bokvist, K.3    Gromada, J.4
  • 15
    • 7444259771 scopus 로고    scopus 로고
    • Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells
    • Fukuchi J., Kokontis J.M., Hiipakka R.A., Chuu C.-P., and Liao S. Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells. Cancer Res. 64 (2004) 7686-7689
    • (2004) Cancer Res. , vol.64 , pp. 7686-7689
    • Fukuchi, J.1    Kokontis, J.M.2    Hiipakka, R.A.3    Chuu, C.-P.4    Liao, S.5
  • 16
    • 1542315629 scopus 로고    scopus 로고
    • The androgen receptor: a potential target for therapy of prostate cancer
    • Santos A.F., Huang H., and Tindall D.J. The androgen receptor: a potential target for therapy of prostate cancer. Steroids 69 (2004) 79-85
    • (2004) Steroids , vol.69 , pp. 79-85
    • Santos, A.F.1    Huang, H.2    Tindall, D.J.3
  • 18
    • 0036112592 scopus 로고    scopus 로고
    • The current state of hormonal therapy for prostate cancer
    • Hellerstedt B.A., and Pienta K.J. The current state of hormonal therapy for prostate cancer. CA Cancer J. Clin. 52 (2002) 154-179
    • (2002) CA Cancer J. Clin. , vol.52 , pp. 154-179
    • Hellerstedt, B.A.1    Pienta, K.J.2
  • 19
    • 0028220323 scopus 로고
    • Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation
    • Kokontis J., Takakura K., Hay N., and Liao S. Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation. Cancer Res. 54 (1994) 1566-1573
    • (1994) Cancer Res. , vol.54 , pp. 1566-1573
    • Kokontis, J.1    Takakura, K.2    Hay, N.3    Liao, S.4
  • 20
    • 0032230358 scopus 로고    scopus 로고
    • Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest
    • Kokontis J.M., Hay N., and Liao S. Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest. Mol. Endocrinol. 12 (1998) 941-953
    • (1998) Mol. Endocrinol. , vol.12 , pp. 941-953
    • Kokontis, J.M.1    Hay, N.2    Liao, S.3
  • 21
    • 28744456066 scopus 로고    scopus 로고
    • Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity
    • Kokontis J.M., Hsu S., Chuu C.-P., Dang M., Fukuchi J., Hiipakka R.A., and Liao S. Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity. Prostate 65 (2005) 287-298
    • (2005) Prostate , vol.65 , pp. 287-298
    • Kokontis, J.M.1    Hsu, S.2    Chuu, C.-P.3    Dang, M.4    Fukuchi, J.5    Hiipakka, R.A.6    Liao, S.7
  • 22
    • 0029859580 scopus 로고    scopus 로고
    • Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride
    • Umekita Y., Hiipakka R.A., Kokontis J.M., and Liao S. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride. Proc. Natl. Acad. Sci. USA 93 (1996) 11802-11807
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11802-11807
    • Umekita, Y.1    Hiipakka, R.A.2    Kokontis, J.M.3    Liao, S.4
  • 23
    • 16844385404 scopus 로고    scopus 로고
    • Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice
    • Chuu C.-P., Hiipakka R.A., Fukuchi J., Kokontis J.M., and Liao S. Androgen causes growth suppression and reversion of androgen-independent prostate cancer xenografts to an androgen-stimulated phenotype in athymic mice. Cancer Res. 65 (2005) 2082-2084
    • (2005) Cancer Res. , vol.65 , pp. 2082-2084
    • Chuu, C.-P.1    Hiipakka, R.A.2    Fukuchi, J.3    Kokontis, J.M.4    Liao, S.5
  • 24
    • 33746176754 scopus 로고    scopus 로고
    • Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist
    • Chuu C.-P., Hiipakka R.A., Kokontis J.M., Fukuchi J., Chen R.-Y., and Liao S. Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist. Cancer Res. 66 (2006) 6482-6486
    • (2006) Cancer Res. , vol.66 , pp. 6482-6486
    • Chuu, C.-P.1    Hiipakka, R.A.2    Kokontis, J.M.3    Fukuchi, J.4    Chen, R.-Y.5    Liao, S.6
  • 25
  • 26
    • 0141954183 scopus 로고    scopus 로고
    • Androgen receptor gene amplification and protein expression in recurrent prostate cancer
    • Ford III O.H., Gregory C.W., Kim D., Smitherman A.B., and Mohler J.L. Androgen receptor gene amplification and protein expression in recurrent prostate cancer. J. Urol. 170 (2003) 1817-1821
    • (2003) J. Urol. , vol.170 , pp. 1817-1821
    • Ford III, O.H.1    Gregory, C.W.2    Kim, D.3    Smitherman, A.B.4    Mohler, J.L.5
  • 27
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman B.J., and Feldman D. The development of androgen-independent prostate cancer. Nat. Rev. Cancer. 1 (2001) 34-45
    • (2001) Nat. Rev. Cancer. , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 28
    • 0025200520 scopus 로고
    • DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water
    • Rago R., Mitchen J., and Wilding G. DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water. Anal. Biochem. 191 (1990) 31-34
    • (1990) Anal. Biochem. , vol.191 , pp. 31-34
    • Rago, R.1    Mitchen, J.2    Wilding, G.3
  • 29
    • 0023948089 scopus 로고
    • Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences
    • Kirschmeier P.T., Housey G.M., Johnson M.D., Perkins A.S., and Weinstein I.B. Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences. DNA 7 (1988) 219-225
    • (1988) DNA , vol.7 , pp. 219-225
    • Kirschmeier, P.T.1    Housey, G.M.2    Johnson, M.D.3    Perkins, A.S.4    Weinstein, I.B.5
  • 30
    • 0023711798 scopus 로고
    • Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA
    • Chen C.A., and Okayama H. Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. Biotechniques 6 (1988) 632-638
    • (1988) Biotechniques , vol.6 , pp. 632-638
    • Chen, C.A.1    Okayama, H.2
  • 31
    • 7444235550 scopus 로고    scopus 로고
    • Androgenic suppression of ATP-binding cassette transporter A1 expression in LNCaP human prostate cancer cells
    • Fukuchi J., Hiipakka R.A., Kokontis J.M., Hsu S., Ko A.L., Fitzgerald M.L., and Liao S. Androgenic suppression of ATP-binding cassette transporter A1 expression in LNCaP human prostate cancer cells. Cancer Res. 64 (2004) 7682-7685
    • (2004) Cancer Res. , vol.64 , pp. 7682-7685
    • Fukuchi, J.1    Hiipakka, R.A.2    Kokontis, J.M.3    Hsu, S.4    Ko, A.L.5    Fitzgerald, M.L.6    Liao, S.7
  • 33
    • 0021261993 scopus 로고
    • The use of a hydroxylapatite-filter steroid receptor assay method in the study of the modulation of androgen receptor interaction
    • Liao S., Witte D., Schilling K., and Chang C. The use of a hydroxylapatite-filter steroid receptor assay method in the study of the modulation of androgen receptor interaction. J. Steroid. Biochem. 20 (1984) 11-17
    • (1984) J. Steroid. Biochem. , vol.20 , pp. 11-17
    • Liao, S.1    Witte, D.2    Schilling, K.3    Chang, C.4
  • 35
    • 0026362280 scopus 로고
    • Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation
    • Kokontis J., Ito K., Hiipakka R.A., and Liao S. Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation. Receptor 1 (1991) 271-279
    • (1991) Receptor , vol.1 , pp. 271-279
    • Kokontis, J.1    Ito, K.2    Hiipakka, R.A.3    Liao, S.4
  • 36
    • 0034731463 scopus 로고    scopus 로고
    • Regions of prostate-specific antigen (PSA) promoter confer androgen-independent expression of PSA in prostate cancer cells
    • Yeung F., Li X., Ellett J., Trapman J., Kao C., and Chung L.W. Regions of prostate-specific antigen (PSA) promoter confer androgen-independent expression of PSA in prostate cancer cells. J. Biol. Chem. 275 (2000) 40846-40855
    • (2000) J. Biol. Chem. , vol.275 , pp. 40846-40855
    • Yeung, F.1    Li, X.2    Ellett, J.3    Trapman, J.4    Kao, C.5    Chung, L.W.6
  • 38
    • 33751210100 scopus 로고    scopus 로고
    • Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice
    • Liu Y., Yan C., Wang Y., Nakagawa Y., Nerio N., Anghel A., Lutfy K., and Friedman T.C. Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice. Endocrinology 147 (2006) 5061-5068
    • (2006) Endocrinology , vol.147 , pp. 5061-5068
    • Liu, Y.1    Yan, C.2    Wang, Y.3    Nakagawa, Y.4    Nerio, N.5    Anghel, A.6    Lutfy, K.7    Friedman, T.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.