Ethanolic extracts and isolated compounds from small-leaf grape (Vitis thunbergii var. taiwaniana) with antihypertensive activities

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 30, 2012, Pages 7435-7441

  Lin, Yin Shiou ^a   Lu, Yeh Lin ^a   Wang, Guei Jane ^d   Chen, Lih Geeng ^e   Wen, Chi Luan ^b,c,f   Hou, Wen Chi ^a,f  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b FISHERIES RESEARCH INSTITUTE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

(+) vitisin A; angiotensin converting enzyme; aortic ring relaxation; blood pressure; spontaneously hypertensive rat (SHR); Vitis thunbergii var. taiwaniana (VTT)

Indexed keywords

(+)-VITISIN A; ANGIOTENSIN-CONVERTING ENZYME; AORTIC RINGS; SPONTANEOUSLY HYPERTENSIVE RAT (SHR); VITIS THUNBERGII VAR. TAIWANIANA (VTT);

BLOOD PRESSURE; BLOOD VESSELS; ENZYMES; FRUITS; OILS AND FATS;

VALUE ENGINEERING;

ALCOHOL; AMPELOPSIN; ANGIOTENSIN DERIVATIVE; ANTIHYPERTENSIVE AGENT; BENZOFURAN DERIVATIVE; CAPTOPRIL; EPSILON-VINIFERIN; FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; STILBENE DERIVATIVE; VINIFERIN; VITISIN A;

ANIMAL; ARTICLE; BLOOD PRESSURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; PLANT LEAF; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SPRAGUE DAWLEY RAT; VITIS; WISTAR KYOTO RAT;

ADMINISTRATION, ORAL; ANGIOTENSINS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZOFURANS; BLOOD PRESSURE; CAPTOPRIL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FLAVONOIDS; MALE; PHENOLS; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; STILBENES; VITIS;

RATTUS; VITACEAE; VITIS; VITIS SINOCINEREA;

EID: 84864746537     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf302445x     Document Type: Article

References (39)

1. Dubow, J.; Fink, M. E. Impact of hypertension on stroke Curr. Atheroscler. Rep. 2011, 13, 298-305
2. Mark, K. S.; Davis, T. P. Stroke: development, prevention and treatment with peptidase inhibitors Peptides 2000, 21, 1965-1973
3. McManus, R. J.; Caulfield, M.; Williams, B. NICE hypertension guideline 2011: evidence based evolution. BMJ 2012, 344.
4. Zaman, M. A.; Oparil, S.; Calhoun, D. A. Drugs targeting the renin-angiotensin-aldosterone system Nat. Rev. Drug Discovery 2002, 1, 621-636
5. Brugts, J. J.; de Maat, M. P.; Danser, A. H.; Boersma, E.; Simoons, M. L. Individualised therapy of angiotensin converting enzyme (ACE) inhibitors in stable coronary artery disease: overview of the primary results of the PERindopril GENEtic association (PERGENE) study Neth. Heart J. 2012, 20, 24-32
6. Fotherby, M. D.; Panayiotou, B. Antihypertensive therapy in the prevention of stroke: what, when and for whom? Drugs 1999, 58, 663-674
7. Sipola, M.; Finckenberg, P.; Korpela, R.; Vapaatalo, H.; Nurminen, M. L. Effect of long-term intake of milk products on blood pressure in hypertensive rats J. Dairy Res. 2002, 69, 103-111
8. Jauhiainen, T.; Vapaatalo, H.; Poussa, T.; Kyrönpalo, S.; Rasmussen, M.; Korpela, R. Lactobacillus helveticus fermented milk lowers blood pressure in hypertensive subjects in 24-h ambulatory blood pressure measurement Am. J. Hypertens. 2005, 12, 1600-1605
9. Aviram, M.; Dornfeld, L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure Atherosclerosis 2001, 158, 195-198
10. Lee, T. H.; Liu, D. Z.; Hsu, F. L.; Wu, W. C.; Hou, W. C. Structure-activity relationships of five myricetin galloylglycosides from leaves of Acacia confusa Bot. Stud. 2006, 47, 37-43
11. Lin, S. Y.; Wang, C. C.; Lu, Y. L.; Wu, W. C.; Hou, W. C. Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria Food. Chem. Toxicol. 2008, 46, 2485-2492
12. Actis-Goretta, L.; Ottaviani, J. I.; Fraga, C. G. Inhibition of angiotensin converting enzyme activity by flavanol-rich foods J. Agric. Food Chem. 2006, 54, 229-234
13. Liu, D. Z.; Liang, Y. C.; Lin, S. Y.; Lin, Y. S.; Wu, W. C.; Hou, W. C.; Su, C. H. Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-Chih) in spontaneously hypertensive rats Biosci. Biotechnol., Biochem. 2007, 71, 23-30
14. Huang, C. Y.; Wen, C. L.; Lu, Y. L.; Lin, Y. S.; Chen, L.; Hou, W. C. Antihypertensive activities of extracts from tissue cultures of Vitis thunbergii var. taiwaniana Bot. Stud. 2010, 51, 317-324
15. Okamoto, K.; Aoki, K. Development of a strain of spontaneously hypertensive rats Jpn. Circ. J. 1963, 27, 282-293
16. Liu, D. Z.; Liang, H. J.; Han, C. H.; Lin, S. Y.; Chen, C. T.; Fan, M.; Hou, W. C. Feeding trial of instant food containing lyophilised yam powder in hypertensive subjects J. Sci. Food Agric 2009, 89, 138-143
17. Chiu, N. Y.; Chang, K. H. The Illustrated Medicinal Plants of Taiwan; SMC Publishing, Taipei, Taiwan, 1995; Vol. 4, p 147.
18. Huang, Y. L.; Tsai, W. J.; Shen, C. C.; Chen, C. C. Resveratrol derivatives from the roots of Vitis thunbergii J. Nat. Prod. 2005, 68, 217-220
19. Chen, L. G.; Wang, C. C. Preparative separation of oligostilbenes from Vitis thunbergii var. taiwaniana by centrifugal partition chromatography followed by Sephadex LH-20 column chromatography Sep. Purif. Technol. 2009, 66, 65-70
20. Dou, D.; Ren, J.; Cooper, M.; He, Y.; Pei, Y.; Takaya, Y.; Niwa, M.; Chen, Y.; Yao, X.; Zhou, R. Polyphenols from Vitis thunbergii Sieb. et Zucc J. Chin. Pharmaceut. Sci. 2003, 12, 57-59
21. Peng, S. C.; Cheng, C. Y.; Sheu, F.; Su, C. H. The antimicrobial activity of heyneanol A extracted from the root of Taiwanese wild grape J. Appl. Microbiol. 2008, 105, 485-491
22. Wang, K. T.; Chen, L. G.; Tseng, S. H.; Huang, J. S.; Hsieh, M. S.; Wang, C. C. Anti-inflammatory effects of resveratrol and oligostilbenes from Vitis thunbergii var. taiwaniana against lipopolysaccharide-induced arthritis J. Agric. Food Chem. 2011, 59, 3649-3656
23. Wang, C. K.; Chen, L. G.; Wen, C. L.; Hou, W. C.; Hung, L. F.; Yen, S. J.; Shen, Y. J.; Lin, S. Y.; Liang, Y. C. Neuroprotective activity of Vitis thunbergii var. taiwaniana extracts in vitro and in vivo J. Med. Food 2010, 13, 170-178
24. Holmquist, B.; Bünning, P.; Riordan, J. F. A continuous spectrophotometric assay for angiotensin converting enzyme Anal. Biochem. 1979, 95, 540-548
25. National Science Council. Guide for the Care and Use of Laboratory Animals; National Science Council, Taiwan, Republic of China, 1994.
26. Liu, Y. H.; Lin, Y. S.; Liu, D. Z.; Han, C. H.; Chen, C. T.; Fan, M.; Hou, W. C. Effects of different types of yam (Dioscorea alata) products on the blood pressure of spontaneously hypertensive rats Biosci. Biotechnol. Biochem. 2009, 73, 1371-1376
27. Wang, G. J.; Shum, A. Y. C.; Lin, Y. L.; Liao, J. F.; Wu, X. C.; Ren, J.; Chen, C. F. Calcium channel blockade in vascular smooth muscle cells: Major hypotensive mechanism of S-petasin, a hypotensive sesquiterpene from Petasites formosanus J. Pharmacol. Exp. Ther. 2001, 297, 240-246
28. Pan, C. H.; Tsai, C. H.; Lin, W. H.; Chen, G. Y.; Wu, C. H. Ethanolic extract of Vitis thunbergii exhibits lipid lowering properties via modulation of the AMPK-ACC pathway in hypercholesterolemic rabbits. Evid. Based Complement. Alternat. Med. 2012, 2012, article ID 436786.
29. Takaya, Y.; Yan, K. X.; Terashima, K.; He, Y. H.; Niwa, M. Biogenetic reactions on stilbenetetramers from Vitaceaeous plants Tetrahedron 2002, 58, 9265-9271
30. Olszanecki, R.; Bujak-Gizycka, B.; Madej, J.; Suski, M.; Wolkow, P.; Jawien, J.; Korbut, R. Kaempferol, but not resveratrol inhibits angiotensin converting enzyme J. Physiol. Pharmacol. 2008, 59, 387-392
31. Balasuriya, B. W. N.; Rupasinghe, H. P. V. Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension Funct. Foods Health Dis. 2011, 1, 172-188
32. Dell'Agli, M.; Buscialà, A.; Bosisio, E. Vascular effects of wine polyphenols Cardiovasc. Res. 2004, 63, 593-602
33. Zenebe, W.; Pechanova, O.; Andriantsitohaina, R. Red wine polyphenols induce vasorelaxation by increased nitric oxide bioactivity Physiol. Res. 2003, 52, 425-432
34. Chen, K. C.; Pace-Asciak, C. R. Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta Gen. Pharmacol. 1996, 27, 363-366
35. Novakovic, A.; Bukarica, L. G.; Kanjuh, V.; Heinle, H. Potassium channels-mediated vasorelaxation of rat aorta induced by resveratrol Basic Clin. Pharmacol. Toxicol. 2006, 99, 360-364
36. Bruckdorfer, R. The basics about nitric oxide Mol. Aspects Med. 2005, 26, 3-31
37. Moon, M. K.; Kang, D. G.; Lee, J. K.; Kim, J. S.; Lee, H. S. Vasodilatory and anti-inflammatory effects of the aqueous extract of rhubarb via a NO-cGMP pathway Life Sci. 2006, 78, 1550-1557
38. Seya, K.; Furukawa, K. I.; Taniguchi, S.; Kodzuka, G.; Oshima, Y.; Niwa, M.; Motomura, S. Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis plants (Vitaceae), in rabbit aorta Clin. Sci. 2003, 105, 73-79
39. Thandapilly, S. J.; Wojciechowski, P.; Behbahani, J.; Louis, X. L.; Yu, L.; Juric, D.; Kopilas, M. A.; Anderson, H. D.; Netticadan, T. Resveratrol prevents the development of pathological cardiac hypetrophy and contractile dysfunction in the SHR without lowering blood pressure Am. J. Hypertens. 2010, 232, 192-196