-
1
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A, Siegel R, Ward E, Murray T, Xu J and Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 57: 43-66, 2007.
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
2
-
-
34547661985
-
L-BLP25: A peptide vaccine strategy in non small cell lung cancer
-
Sangha R and Butts C: L-BLP25: a peptide vaccine strategy in non small cell lung cancer. Clin Cancer Res 13: 4652-4654, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4652-4654
-
-
Sangha, R.1
Butts, C.2
-
3
-
-
42549106307
-
Final results of a multi-center, double-blind, randomized, placebo-controlled Phase II study to assess the efficacy of MAGE-A3 immunotherapeutic as adjuvant therapy in stage IB/II non-small cell lung cancer (NSCLC)
-
Vansteenkiste J, Zielinski M, Linder A, et al: Final results of a multi-center, double-blind, randomized, placebo-controlled Phase II study to assess the efficacy of MAGE-A3 immunotherapeutic as adjuvant therapy in stage IB/II non-small cell lung cancer (NSCLC). J Clin Oncol (Suppl 25): 398s, 2007.
-
(2007)
J Clin Oncol
, Issue.SUPPL. 25
-
-
Vansteenkiste, J.1
Zielinski, M.2
Linder, A.3
-
4
-
-
0026322151
-
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
-
van der Bruggen P, Traversari C, Chomez P, et al: A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254: 1643-1647, 1991.
-
(1991)
Science
, vol.254
, pp. 1643-1647
-
-
van der Bruggen, P.1
Traversari, C.2
Chomez, P.3
-
5
-
-
11144355077
-
Simultaneous cellular and humoral immune response against mutated p53 in a patient with lung cancer
-
Ichiki Y, Takenoyama M, Mizukami M, et al: Simultaneous cellular and humoral immune response against mutated p53 in a patient with lung cancer. J Immunol 172: 4844-4850, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 4844-4850
-
-
Ichiki, Y.1
Takenoyama, M.2
Mizukami, M.3
-
6
-
-
33645239336
-
A point mutation in the NFYC gene generates an antigenic peptide recognized by autologous cytolytyic T lymphocytes on a human squamous cell lung carcinoma
-
Takenoyama M, Baurain JF, Yasuda M, et al: A point mutation in the NFYC gene generates an antigenic peptide recognized by autologous cytolytyic T lymphocytes on a human squamous cell lung carcinoma. Int J Cancer 118: 1992-1997, 2006.
-
(2006)
Int J Cancer
, vol.118
, pp. 1992-1997
-
-
Takenoyama, M.1
Baurain, J.F.2
Yasuda, M.3
-
7
-
-
29144514645
-
Effector memory T cells, early metastasis, and survival in colorectal cancer
-
Pages F, Berger A, Camus M, et al: Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 353: 2654-2666, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 2654-2666
-
-
Pages, F.1
Berger, A.2
Camus, M.3
-
8
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
Zhang L, Conejo-Garcia JR, Katsaros D, et al: Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med 348: 203-213, 2003.
-
(2003)
N Engl J Med
, vol.348
, pp. 203
-
-
Zhang, L.1
Conejo-Garcia, J.R.2
Katsaros, D.3
-
9
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC and Restifo NP: Cancer immunotherapy: moving beyond current vaccines. Nat Med 10: 909-915, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
10
-
-
0035806323
-
Human cd25(+)cd4(+) t regulatory cells suppress naïve and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings MK, Sangregorio R and Roncarolo MG: Human cd25(+)cd4(+) t regulatory cells suppress naïve and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med 193: 1295-1302, 2001.
-
(2001)
J Exp Med
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
11
-
-
0035806289
-
Certified professionals: CD4(+)CD25(+) suppressor T cells
-
Shevach EM: Certified professionals: CD4(+)CD25(+) suppressor T cells. J Exp Med 193: 41-46, 2001.
-
(2001)
J Exp Med
, vol.193
, pp. 41-46
-
-
Shevach, E.M.1
-
12
-
-
0034613767
-
Induction of interleukin 10-producing, non proliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
Jonuleit H, Schmitt E, Schuler G, Knop J and Enk AH: Induction of interleukin 10-producing, non proliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192: 1213-1222, 2000.
-
(2000)
J Exp Med
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
13
-
-
0035546070
-
CD4(+) regulatory T cells
-
Read S and Powrie F: CD4(+) regulatory T cells. Curr Opin Immunol 13: 644-649, 2001.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 644-649
-
-
Read, S.1
Powrie, F.2
-
14
-
-
0034941320
-
Histological typing of lung and pleural tumours: Third edition
-
Gibbs AR and Thunnissen FB: Histological typing of lung and pleural tumours: third edition. J Clin Pathol 54: 498-499, 2001.
-
J Clin Pathol
, vol.54
, pp. 498
-
-
Gibbs, A.R.1
Thunnissen, F.B.2
-
15
-
-
0030912190
-
Revisions in the international system for staging lung cancer
-
Mountain CF: Revisions in the international system for staging lung cancer. Chest 111: 1710-1717, 1997.
-
(1997)
Chest
, vol.111
, pp. 1710-1717
-
-
Mountain, C.F.1
-
16
-
-
0036305729
-
Establishment of 15 cancer cell lines from patients with lung cancer and the potential tools for immunotherapy
-
Sugaya M, Takenoyama M, Osaki T, et al: Establishment of 15 cancer cell lines from patients with lung cancer and the potential tools for immunotherapy. Chest 122: 282-288, 2002.
-
(2002)
Chest
, vol.122
, pp. 282-288
-
-
Sugaya, M.1
Takenoyama, M.2
Osaki, T.3
-
17
-
-
0035067301
-
Successful induction of tumor-specific cytotoxic T lymphocytes from patients with non-small cell lung cancer using CD80-transfected autologous tumor cells
-
Takenoyama M, Yoshino I, Eifuku R, et al: Successful induction of tumor-specific cytotoxic T lymphocytes from patients with non-small cell lung cancer using CD80-transfected autologous tumor cells. Jpn J Cancer Res 92: 309-315, 2001.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 309-315
-
-
Takenoyama, M.1
Yoshino, I.2
Eifuku, R.3
-
18
-
-
34249907598
-
Cytokine production of lung cancer cell lines: Correlation between their production and the inflammatory/immunological responses both in vivo and in vitro
-
Fukuyama T, Ichiki Y, Yamada S, et al: Cytokine production of lung cancer cell lines: correlation between their production and the inflammatory/immunological responses both in vivo and in vitro. Cancer Sci 98: 1048-1054, 2007.
-
(2007)
Cancer Sci
, vol.98
, pp. 1048-1054
-
-
Fukuyama, T.1
Ichiki, Y.2
Yamada, S.3
-
19
-
-
33746342994
-
Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
Sakaguchi S, Ono M, Setoguchi R, et al: Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 212: 8-27, 2006.
-
(2006)
Immunol Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
-
20
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA and Rudensky AY: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4: 330-336, 2003.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
21
-
-
0037312480
-
Increase of regulatory T cells in the peripheral blood of cancer patients
-
Wolf AM, Wolf D, Steurer M, Gastl G, Gunsilius E and Grubeck-Loebenstein B: Increase of regulatory T cells in the peripheral blood of cancer patients. Clin Cancer Res 9: 606-612, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 606-612
-
-
Wolf, A.M.1
Wolf, D.2
Steurer, M.3
Gastl, G.4
Gunsilius, E.5
Grubeck-Loebenstein, B.6
-
22
-
-
16844378685
-
Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
-
Ormandy LA, Hillemann T, Wedemeyer H, Manns MP, Greten TF and Korangy F: Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res 65: 2457-2464, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 2457-2464
-
-
Ormandy, L.A.1
Hillemann, T.2
Wedemeyer, H.3
Manns, M.P.4
Greten, T.F.5
Korangy, F.6
-
23
-
-
0035874949
-
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
Woo EY, Chu CS, Goletz TJ, et al: Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res 61: 4766-4772, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
Chu, C.S.2
Goletz, T.J.3
-
24
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, et al: Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10: 942-949, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
-
25
-
-
34247261531
-
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
-
Bates GJ, Fox SB, Han C, et al: Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 24: 5373-5380, 2006.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
-
26
-
-
26844464792
-
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-h-dependent manner
-
Ghiringhelli F, Menard C, Terme M, et al: CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-h-dependent manner. J Exp Med 202: 1075-1085, 2005.
-
(2005)
J Exp Med
, vol.202
, pp. 1075-1085
-
-
Ghiringhelli, F.1
Menard, C.2
Terme, M.3
-
27
-
-
33845590308
-
Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients
-
Petersen RP, Campa MJ, Sperlazza J, et al: Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients. Cancer 107: 2866-2872, 2006.
-
(2006)
Cancer
, vol.107
, pp. 2866-2872
-
-
Petersen, R.P.1
Campa, M.J.2
Sperlazza, J.3
-
28
-
-
17144400393
-
TGF-beta 1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
-
Marie JC, Letterio JJ, Gavin M and Rudensky AY: TGF-beta 1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 201: 1061-1067, 2005.
-
(2005)
J Exp Med
, vol.201
, pp. 1061-1067
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
29
-
-
58349116249
-
Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
-
Wieczorek G, Asemissen A, Model F, et al: Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res 69: 599-608, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 599-608
-
-
Wieczorek, G.1
Asemissen, A.2
Model, F.3
-
30
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
Walunas TL, Bakker CY and Bluestone JA: CTLA-4 ligation blocks CD28-dependent T cell activation. J Exp Med 183: 2541-2550, 1996.
-
(1996)
J Exp Med
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
31
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel MF and Allison JP: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 182: 459-465, 1995.
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
32
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V and Powrie F: Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 192: 295-302, 2000.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
33
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, Lenschow DJ, Rhee L, et al: B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12: 431-440, 2000.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
-
34
-
-
0029789389
-
CTLA-4: A negative regulator of autoimmune disease
-
Karandikar NJ, Vanderlugt CL, Walunas TL, Miller SD and Bluestone JA: CTLA-4: A negative regulator of autoimmune disease. J Exp Med 184: 783-788, 1996.
-
(1996)
J Exp Med
, vol.184
, pp. 783-788
-
-
Karandikar, N.J.1
Vanderlugt, C.L.2
Walunas, T.L.3
Miller, S.D.4
Bluestone, J.A.5
-
35
-
-
0033563271
-
CTLA-4-Mediated inhibition of early events of T cell proliferation
-
Brunner MC, Chambers CA, Chan FK, Hanke J, Winoto A and Allison JP: CTLA-4-Mediated inhibition of early events of T cell proliferation. J Immunol 162: 5813-5820, 1999.
-
(1999)
J Immunol
, vol.162
, pp. 5813-5820
-
-
Brunner, M.C.1
Chambers, C.A.2
Chan, F.K.3
Hanke, J.4
Winoto, A.5
Allison, J.P.6
-
36
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF and Allison JP: Enhancement of antitumor immunity by CTLA-4 blockade. Science 271: 1734-1736, 1996.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
37
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
van Elsas A, Hurwitz AA and Allison JP: Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 190: 355-366, 1999.
-
(1999)
J Exp Med
, vol.190
, pp. 355-366
-
-
van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
38
-
-
17944364189
-
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
van Elsas A, Sutmuller RP, Hurwitz AA, et al: Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J Exp Med 194: 481-489, 2001.
-
(2001)
J Exp Med
, vol.194
, pp. 481-489
-
-
van Elsas, A.1
Sutmuller, R.P.2
Hurwitz, A.A.3
-
39
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi FS, Mihm MC, Soiffer RJ, et al: Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci USA 100: 4712-4717, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
-
40
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM, et al: Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 100: 8372-8377, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
41
-
-
42949105127
-
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
-
Hodi FS, Butler M, Oble DA, et al: Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci USA 105: 3005-3010, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3005-3010
-
-
Hodi, F.S.1
Butler, M.2
Oble, D.A.3
-
42
-
-
33646794392
-
Checkpoint blockade in cancer immunotherapy
-
Korman AJ, Peggs KS and Allison JP: Checkpoint blockade in cancer immunotherapy. Adv Immunol 90: 297-339, 2006.
-
(2006)
Adv Immunol
, vol.90
, pp. 297-339
-
-
Korman, A.J.1
Peggs, K.S.2
Allison, J.P.3
-
43
-
-
34548240159
-
Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
-
Ribas A, Hanson DC, Noe DA, et al: Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. Oncologist 12: 873-883, 2007.
-
(2007)
Oncologist
, vol.12
, pp. 873-883
-
-
Ribas, A.1
Hanson, D.C.2
Noe, D.A.3
-
44
-
-
34447643405
-
Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor
-
Yamaguchi T, Hirota K, Nagahama K, et al: Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor. Immunity 27: 145-159, 2007.
-
(2007)
Immunity
, vol.27
, pp. 145-159
-
-
Yamaguchi, T.1
Hirota, K.2
Nagahama, K.3
|