Determination of deamidation artifacts introduced by sample preparation using 18O-labeling and tandem mass spectrometry analysis

Analytical Chemistry

Volumn 84, Issue 15, 2012, Pages 6355-6360

  Du, Yi ^a   Wang, Fengqiang ^a   May, Kimberly ^a   Xu, Wei ^a   Liu, Hongcheng ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYL GROUPS; DEAMIDATION; ENZYMATIC DIGESTIONS; FIXED NUMBERS; ISOTOPIC DISTRIBUTIONS; LC-MS ANALYSIS; PEPTIDE MAPPING; SAMPLE PREPARATION; SIDE-CHAINS; TANDEM MASS SPECTROMETRY; WEIGHT DIFFERENCE;

ATOMS; MASS SPECTROMETRY; MOLECULAR WEIGHT;

PEPTIDES;

ASPARAGINE; MONOCLONAL ANTIBODY; OXYGEN; PEPTIDE; TRYPSIN;

ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOTOPE LABELING; METABOLISM; TANDEM MASS SPECTROMETRY;

ANTIBODIES, MONOCLONAL; ASPARAGINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROLYSIS; ISOTOPE LABELING; OXYGEN ISOTOPES; PEPTIDES; TANDEM MASS SPECTROMETRY; TRYPSIN;

EID: 84864629154     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac3013362     Document Type: Article

References (32)

1. Harris, R. J.; Kabakoff, B.; Macchi, F. D.; Shen, F. J.; Kwong, M.; Andya, J. D.; Shire, S. J.; Bjork, N.; Totpal, K.; Chen, A. B. J. Chromatogr., B: Biomed. Sci. Appl. 2001, 752, 233-245
2. Huang, L.; Lu, J.; Wroblewski, V. J.; Beals, J. M.; Riggin, R. M. Anal. Chem. 2005, 77, 1432-1439
3. Lyubarskaya, Y.; Houde, D.; Woodard, J.; Murphy, D.; Mhatre, R. Anal. Biochem. 2006, 348, 24-39
4. Zheng, J. Y.; Janis, L. J. Int. J. Pharm. 2006, 308, 46-51
5. Harris, R.; Shire, S. J.; Winter, C. Drug Dev. Res. 2004, 61, 137-154
6. Chelius, D.; Rehder, D. S.; Bondarenko, P. V. Anal. Chem. 2005, 77, 6004-6011
7. Terashima, I.; Koga, A.; Nagai, H. Anal. Biochem. 2007, 368, 49-60
8. Gaza-Bulseco, G.; Li, B.; Bulseco, A.; Liu, H. C. Anal. Chem. 2008, 80, 9491-9498
9. Sinha, S.; Zhang, L.; Duan, S.; Williams, T. D.; Vlasak, J.; Ionescu, R.; Topp, E. M. Protein Sci. 2009, 18, 1573-1584
10. Wang, L.; Amphlett, G.; Lambert, J. M.; Blättler, W; Zhang, W. Pharm. Res. 2005, 22, 1338-1349
11. Mukherjee, R.; Adhikary, L.; Khedkar, A.; Iyer, H. Rapid Commun. Mass Spectrom. 2010, 24, 879-884
12. Liu, Y. D.; van Enk, J. Z.; Flynn, G. C. Biologicals. 2009, 37, 313-322
13. Perkins, M.; Theiler, R.; Lunte, S.; Jeschke, M. Pharm. Res. 2000, 17, 1110-1117
14. Vlasak, J.; Bussat, M. C.; Wang, S.; Wagner-Rousset, E.; Schaefer, M.; Klinguer-Hamour, C.; Kirchmeier, M.; Corvaia, N.; Ionescu, R.; Beck, A. Anal. Biochem. 2009, 392, 145-154
15. Zhang, W.; Czupryn, M. J. J. Pharm. Biomed. Anal. 2003, 30, 1479-1490
16. Geiger, T.; Clarke, S. J. Biol. Chem. 1987, 262, 785-794
17. Niebecker, R.; Kloft, C. Curr. Drug Safety 2010, 5, 275-286
18. Mamula, M. J.; Gee, R. J.; Elliott, J. I.; Sette, A.; Southwood, S.; Jones, P. J.; Blier, P. R. J. Biol. Chem. 1999, 274, 22321-22327
19. Moss, C. X.; Matthews, S. P.; Lamont, D. J.; Watts, C. J. Biol. Chem. 2005, 280, 18498-18503
20. Cacia, J.; Keck, R.; Presta, L. G.; Frenz, J. Biochemistry 1996, 35, 1897-1903
21. Rehder, D. S.; Chelius, D.; McAuley, A.; Dillon, T. M.; Xiao, G.; Crouse-Zeineddini, J.; Vardanyan, L.; Perico, N.; Mukku, V.; Brems, D. N.; Matsumura, M.; Bondarenko, P. V. Biochemistry 2008, 47, 2518-2530
22. Ren, D.; Pipes, G. D.; Liu, D.; Shih, L. Y.; Nichols, A. C.; Treuheit, M. J.; Brems, D. N.; Bondarenko, P. V. Anal. Biochem. 2009, 392, 12-21
23. Krokhin, O. V.; Antonovici, M.; Ens, W.; Wilkins, J. A.; Standing, K. G. Anal. Chem. 2006, 78, 6645-6650
24. Stroop, S. D. Rapid Commun. Mass Spectrom. 2007, 21, 830-836
25. Li, X.; Cournoyer, J. J.; Lin, C.; O'Connor, P. B. J. Am. Soc. Mass Spectrom. 2008, 19, 855-864
26. Schnolzer, M.; Jedrzejewski, P.; Lehmann, W. D. Electrophoresis 1996, 17, 945-953
27. Hajkova, D.; Rao, K. C.; Miyagi, M. J. Proteome Res. 2006, 5, 1667-1673
28. Miyagi, M.; Rao, K. C. Mass Spectrom. Rev. 2007, 26, 121-136
29. Fenselau, C.; Yao, X. J. Proteome Res. 2009, 8, 2140-2143
30. Alfaro, J. F.; Gillies, L. A.; Sun, H. G.; Dai, S.; Zang, T.; Klaene, J. J.; Kim, B. J.; Lowenson, J. D.; Clarke, S. G.; Karger, B. L.; Zhou, Z. S. Anal. Chem. 2008, 80, 3882-3889
31. Ni, W.; Dai, S.; Karger, B. L.; Zhou, Z. S. Anal. Chem. 2010, 82, 7485-7491
32. Liu, M.; Cheetham, J.; Cauchon, N.; Ostovic, J.; Ni, W.; Ren, D.; Zhou, Z. S. Anal. Chem. 2012, 84, 1056-1062