Chemo-enzymatic detection of protein isoaspartate using protein isoaspartate methyltransferase and hydrazine trapping

Analytical Chemistry

Volumn 80, Issue 10, 2008, Pages 3882-3889

  Alfaro, Joshua F ^a   Gillies, Laura A ^a   Sun, He G ^c   Dai, Shujia ^c   Zang, Tianzhu ^c   Klaene, Joshua J ^c   Byung, Ju Kim ^c   Lowenson, Jonathan D ^b   Clarke, Steven G ^b   Karger, Barry L ^c   Zhaohui, Sunny Zhou ^a,c  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL SYSTEMS; CHEMICAL MODIFICATION; DISEASES; ELECTROSPRAY IONIZATION; ESTERS; HYDRAZINE; ISOMERIZATION; MASS SPECTROMETRY;

CHEMO-ENZYMATIC DETECTION; HUMAN DISEASES; ISOASPARTATE PROTEINS;

ENZYME ACTIVITY;

ALDEHYDE; ASPARAGINE; ASPARTIC ACID; CARBENE; ESTER DERIVATIVE; HYDRAZIDE DERIVATIVE; HYDRAZINE; ISOASPARTATE METHYLTRANSFERASE; ISOASPARTIC ACID; METHYLTRANSFERASE; RESIN;

AFFINITY CHROMATOGRAPHY; AQUEOUS SOLUTION; ARTICLE; BIOTRANSFORMATION; DEAMINATION; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE SPECTROSCOPY; ISOMERIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR STABILITY; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEOMICS; QUANTITATIVE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

CHROMATOGRAPHY, AFFINITY; HYDRAZINES; ISOASPARTIC ACID; PROTEIN D-ASPARTATE-L-ISOASPARTATE METHYLTRANSFERASE; PROTEINS; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 43949127087     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac800251q     Document Type: Article

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