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Volumn 16, Issue 2, 2004, Pages 101-109

Modafinil: Preclinical, clinical, and post-marketing surveillance - A review of abuse liability issues

Author keywords

Addiction; Modafinil; Substance abuse

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPHA ADRENERGIC RECEPTOR; AMFEBUTAMONE; AMPHETAMINE; CAFFEINE; COCAINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DEXAMPHETAMINE; DOPAMINE; DOPAMINE TRANSPORTER; EPHEDRINE; ETHINYLESTRADIOL; GLUTAMIC ACID; HALOPERIDOL; METHYLPHENIDATE; MODAFINIL; PHENOXYBENZAMINE; PRAZOSIN; PROTEIN C FOS; RESERPINE; TRIAZOLAM;

EID: 4143088220     PISSN: 10401237     EISSN: None     Source Type: Journal    
DOI: 10.1080/10401230490453743     Document Type: Review
Times cited : (135)

References (44)
  • 1
    • 0025270451 scopus 로고
    • Central alpha 1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil: Studies with experimental animals
    • Duteil J, Rambert FA, Pesssonnier J, Hermant JF, Gombert R, Assous E. Central alpha 1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil: studies with experimental animals. Eur J. Pharmacol 1990; 180:49-58.
    • (1990) Eur J Pharmacol , vol.180 , pp. 49-58
    • Duteil, J.1    Rambert, F.A.2    Pesssonnier, J.3    Hermant, J.F.4    Gombert, R.5    Assous, E.6
  • 2
    • 0028876379 scopus 로고
    • Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice
    • Simon P, Hemet C, Ramassamy C, Costentin J. Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice. Eur Neuropsychopharmacol 1995; 4:509-514.
    • (1995) Eur Neuropsychopharmacol , vol.4 , pp. 509-514
    • Simon, P.1    Hemet, C.2    Ramassamy, C.3    Costentin, J.4
  • 3
    • 0030775911 scopus 로고    scopus 로고
    • Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat
    • Edgar DM, Seidel WF. Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat. J Pharmacol Exp Ther 1997; 283(2), 757-769.
    • (1997) J Pharmacol Exp Ther , vol.283 , Issue.2 , pp. 757-769
    • Edgar, D.M.1    Seidel, W.F.2
  • 4
    • 0342545934 scopus 로고    scopus 로고
    • Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy
    • US Modafinil in Narcolepsy Multicenter Study Group. Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy. Neurology 1998; 54(5):1166-1175.
    • (1998) Neurology , vol.54 , Issue.5 , pp. 1166-1175
  • 5
    • 0034491316 scopus 로고    scopus 로고
    • Efficacy of modafinil compared to dextroamphetamine for the treatment of attention-deficithyperactivity disorder in adults
    • Taylor FB, Russo J. Efficacy of modafinil compared to dextroamphetamine for the treatment of attention-deficithyperactivity disorder in adults. J Child Adolesc Psychopharmacol 2000; 10(4):311-320.
    • (2000) J Child Adolesc Psychopharmacol , vol.10 , Issue.4 , pp. 311-320
    • Taylor, F.B.1    Russo, J.2
  • 6
    • 0035139262 scopus 로고    scopus 로고
    • Effect of modafinil in children with attention-deficit/hyperactivity disorder: An open-label study
    • Rugino TA, Copley TC. Effect of modafinil in children with attention-deficit/hyperactivity disorder: An open-label study. J Am Acad Child Adolesc Psychiatry 2001; 40(2):230-235.
    • (2001) J Am Acad Child Adolesc Psychiatry , vol.40 , Issue.2 , pp. 230-235
    • Rugino, T.A.1    Copley, T.C.2
  • 7
    • 0034078972 scopus 로고    scopus 로고
    • Modafinil augmentation of antidepressant treatment in depression
    • Menza MA, Kaufman KR, Castellanos A. Modafinil augmentation of antidepressant treatment in depression. J Clin Psychiatry 2000; 61(5):378-381.
    • (2000) J Clin Psychiatry , vol.61 , Issue.5 , pp. 378-381
    • Menza, M.A.1    Kaufman, K.R.2    Castellanos, A.3
  • 9
    • 0035057580 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hyopnea syndrome
    • Kingshott RN, Vennelle M, Coleman EL, Engleman HM, Mackay TW, Douglas NJ. Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hyopnea syndrome. Am J Respir Crit Care Med 2001; 163:918-923.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 918-923
    • Kingshott, R.N.1    Vennelle, M.2    Coleman, E.L.3    Engleman, H.M.4    Mackay, T.W.5    Douglas, N.J.6
  • 11
    • 0012388698 scopus 로고    scopus 로고
    • Efficacy and safety of modafinil as adjunctive therapy for excessive sleepiness associated with obstructive sleep apnea
    • Black JE, Douglas NJ, Earl CQ, Modafinil OSA Study Group. Efficacy and safety of modafinil as adjunctive therapy for excessive sleepiness associated with obstructive sleep apnea (abstract). Sleep 2002: 25(Suppl 1): A22.
    • (2002) Sleep , vol.25 , Issue.SUPPL. 1
    • Black, J.E.1    Douglas, N.J.2    Earl, C.Q.3
  • 12
    • 0037114678 scopus 로고    scopus 로고
    • Modafinil for the treatment of daytime sleepiness in Parkinson's disease: A double-blind, randomized, crossover, placebo-controlled polygraphic trial
    • Hogl B, Saleto M, Brandauer E, Glatzl S, Frauscher B, Seppi K, Ulmer H, Wenning G, Poewe W. Modafinil for the treatment of daytime sleepiness in Parkinson's disease: a double-blind, randomized, crossover, placebo-controlled polygraphic trial. Sleep 2002: 25(8):905-909.
    • (2002) Sleep , vol.25 , Issue.8 , pp. 905-909
    • Hogl, B.1    Saleto, M.2    Brandauer, E.3    Glatzl, S.4    Frauscher, B.5    Seppi, K.6    Ulmer, H.7    Wenning, G.8    Poewe, W.9
  • 13
    • 0037355884 scopus 로고    scopus 로고
    • Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease
    • Adler CH, Caviness JN, Hentz JG, Lind M, Tiede J. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov Disord 2003; 13(3):287-293.
    • (2003) Mov Disord , vol.13 , Issue.3 , pp. 287-293
    • Adler, C.H.1    Caviness, J.N.2    Hentz, J.G.3    Lind, M.4    Tiede, J.5
  • 15
    • 0036038978 scopus 로고    scopus 로고
    • Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study
    • Zifko UA, Rupp M, Schwarz S, Zipko HT, Maida EM. Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study. J Neurol 2002; 249(8): 983-987.
    • (2002) J Neurol , vol.249 , Issue.8 , pp. 983-987
    • Zifko, U.A.1    Rupp, M.2    Schwarz, S.3    Zipko, H.T.4    Maida, E.M.5
  • 16
    • 4143055393 scopus 로고    scopus 로고
    • Cephalon, Inc., West Chester, PA
    • Provigil® (modafinil) Package Insert: Cephalon, Inc., West Chester, PA, 2002. Available at: http://www.provigil.com
    • (2002) Provigil® (Modafinil) Package Insert
  • 17
    • 0037275524 scopus 로고    scopus 로고
    • Clinical pharmacokinetic profile of modafinil
    • Robertson P Jr., Hellriegel ET. Clinical pharmacokinetic profile of modafinil. Clin Pharmacokinet 2003; 42(2):123-137.
    • (2003) Clin Pharmacokinet , vol.42 , Issue.2 , pp. 123-137
    • Robertson Jr., P.1    Hellriegel, E.T.2
  • 18
    • 0030477691 scopus 로고    scopus 로고
    • Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat
    • Lin JS, Hou Y, Jouvet M. Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat. Proc Natl Acad Sci USA 1996; 98(24):14128-14133.
    • (1996) Proc Natl Acad Sci USA , vol.98 , Issue.24 , pp. 14128-14133
    • Lin, J.S.1    Hou, Y.2    Jouvet, M.3
  • 19
    • 0032579408 scopus 로고    scopus 로고
    • Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil
    • Engber TM, Koury EJ, Dennis SA, Miller MS, Contreras PC, Bhat RV. Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil. Neurosci Lett 1998; 241(2-3):95-98.
    • (1998) Neurosci Lett , vol.241 , Issue.2-3 , pp. 95-98
    • Engber, T.M.1    Koury, E.J.2    Dennis, S.A.3    Miller, M.S.4    Contreras, P.C.5    Bhat, R.V.6
  • 20
    • 0034668848 scopus 로고    scopus 로고
    • Hypothalamic arousal regions are activated during Modafinil-induced wakefulness
    • Scammel TE, Estabrooke IV, McCarthy MT, et al. Hypothalamic arousal regions are activated during Modafinil-induced wakefulness. Journal of Neuroscience 2000; 20(22):8620-8628.
    • (2000) Journal of Neuroscience , vol.20 , Issue.22 , pp. 8620-8628
    • Scammel, T.E.1    Estabrooke, I.V.2    McCarthy, M.T.3
  • 21
    • 0028015747 scopus 로고
    • Modafinil binds to the dopamine uptake carrier site with low affinity
    • Mignot E, Nishino S, Guilleminault C, Dement WC. Modafinil binds to the dopamine uptake carrier site with low affinity. Sleep 1994; 17(5):436-437.
    • (1994) Sleep , vol.17 , Issue.5 , pp. 436-437
    • Mignot, E.1    Nishino, S.2    Guilleminault, C.3    Dement, W.C.4
  • 22
    • 4143099811 scopus 로고    scopus 로고
    • Personal Communication. July 10
    • Roth BL. Personal Communication. July 10, 2003.
    • (2003)
    • Roth, B.L.1
  • 24
    • 0037114067 scopus 로고    scopus 로고
    • Role of brain alphalB adrenoreceptors in modafinil-induced behavioral activity
    • Stone EA, Cotecchia S, Lin Y, Quartermain D. Role of brain alphalB adrenoreceptors in modafinil-induced behavioral activity. Synapse 2002; 42:269-270.
    • (2002) Synapse , vol.42 , pp. 269-270
    • Stone, E.A.1    Cotecchia, S.2    Lin, Y.3    Quartermain, D.4
  • 25
    • 0031574307 scopus 로고    scopus 로고
    • Modafinil: An antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers
    • Ferraro L, Antonelli T, O'Connor WT, et al. Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers. Biol Psychiatry 1997; 42:1181-1183.
    • (1997) Biol Psychiatry , vol.42 , pp. 1181-1183
    • Ferraro, L.1    Antonelli, T.2    O'Connor, W.T.3
  • 26
    • 0033555585 scopus 로고    scopus 로고
    • Effects of the vigilant-promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus
    • Perez de la Mora M, Aguilar-Garcia A, Ramon-Frias T, et al. Effects of the vigilant-promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus. Neuroscience Letter 1999; 259:181-185.
    • (1999) Neuroscience Letter , vol.259 , pp. 181-185
    • Perez De La Mora, M.1    Aguilar-Garcia, A.2    Ramon-Frias, T.3
  • 28
    • 0033939751 scopus 로고    scopus 로고
    • Antiparkinsonian and neuroprotective effects of modafinil in the MPTP-treated common marmoset
    • Jenner P, Zeng BY, Smith LA, et al. Antiparkinsonian and neuroprotective effects of modafinil in the MPTP-treated common marmoset. Exp Brain Res. 2000; 133(2):178-188.
    • (2000) Exp Brain Res , vol.133 , Issue.2 , pp. 178-188
    • Jenner, P.1    Zeng, B.Y.2    Smith, L.A.3
  • 29
    • 0034882387 scopus 로고    scopus 로고
    • Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment
    • Davidson C, Gow AJ, Lee TH, Ellinwood EH. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Brain Res Rev 2001; 36(1):1-22.
    • (2001) Brain Res Brain Res Rev , vol.36 , Issue.1 , pp. 1-22
    • Davidson, C.1    Gow, A.J.2    Lee, T.H.3    Ellinwood, E.H.4
  • 30
    • 0033623774 scopus 로고    scopus 로고
    • (+/-) 3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: Clinical studies
    • McCann UD, Eligulashvili V, Ricaurte, GA: (+/-) 3,4- Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: clinical studies. Neuropsychobiology 2000; 42(1):11-16.
    • (2000) Neuropsychobiology , vol.42 , Issue.1 , pp. 11-16
    • McCann, U.D.1    Eligulashvili, V.2    Ricaurte, G.A.3
  • 31
    • 0029822795 scopus 로고    scopus 로고
    • Evaluation of the cocaine like discriminative stimulus effects and reinforcing effects of modafinil
    • Gold LH, Balster RL. Evaluation of the cocaine like discriminative stimulus effects and reinforcing effects of modafinil. Psychopharmacol 1996; 126:286-292.
    • (1996) Psychopharmacol , vol.126 , pp. 286-292
    • Gold, L.H.1    Balster, R.L.2
  • 34
    • 0027363308 scopus 로고
    • Subjective effects of modafinil, a new centeral adrenergic stimulant in healthy volunteers: A comparison with amphetamine, caffeine, and placebo
    • Warot D, Corruble E, Payan C, Weil JS, Puech AJ. Subjective effects of modafinil, a new centeral adrenergic stimulant in healthy volunteers: a comparison with amphetamine, caffeine, and placebo. Eur Psychiatry 1993; 8:201-208.
    • (1993) Eur Psychiatry , vol.8 , pp. 201-208
    • Warot, D.1    Corruble, E.2    Payan, C.3    Weil, J.S.4    Puech, A.J.5
  • 35
    • 0141715201 scopus 로고    scopus 로고
    • Distinguishing modafinil from methylphenidate in a study of abuse potential: Gender comparison
    • June 14-19, Nashville, TN
    • Jasinski DR. Distinguishing modafinil from methylphenidate in a study of abuse potential: gender comparison. Presented at the Annual Meeting of the College on Problems of Drug Dependence, June 14-19, 1997, Nashville, TN.
    • (1997) Annual Meeting of the College on Problems of Drug Dependence
    • Jasinski, D.R.1
  • 36
    • 0343963779 scopus 로고    scopus 로고
    • Evaluation of the abuse liability of modafinil and other drugs for excessive daytime sleepiness associated with narcolepsy
    • Jasinski DR, Kovacevic-Ristanovi ĆR. Evaluation of the abuse liability of modafinil and other drugs for excessive daytime sleepiness associated with narcolepsy. Clinical Neuropharmacology 2000; 23(3): 149-156.
    • (2000) Clinical Neuropharmacology , vol.23 , Issue.3 , pp. 149-156
    • Jasinski, D.R.1    Kovacevic-Ristanovi, Ć.R.2
  • 39
    • 0037401522 scopus 로고    scopus 로고
    • Modafinil and cocaine: A double-blind, placebo-controlled drug interaction study
    • Dackis CA, Lynch KG, Yu E, et al. Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study. Drug Alcohol Depend 2003; 70(1):29-37.
    • (2003) Drug Alcohol Depend , vol.70 , Issue.1 , pp. 29-37
    • Dackis, C.A.1    Lynch, K.G.2    Yu, E.3
  • 42
    • 0034061801 scopus 로고    scopus 로고
    • An evaluation of the abuse potential of modafinil using methylphenidate as a reference
    • Jasinski DR. An evaluation of the abuse potential of modafinil using methylphenidate as a reference. Journal of Psychopharmacology 2000; 14(1):53-60.
    • (2000) Journal of Psychopharmacology , vol.14 , Issue.1 , pp. 53-60
    • Jasinski, D.R.1
  • 43
    • 4143050857 scopus 로고    scopus 로고
    • Personal Communication. June 15
    • Galloway G. Personal Communication. June 15, 2003.
    • (2003)
    • Galloway, G.1
  • 44
    • 0036337919 scopus 로고    scopus 로고
    • Clinical applications of modafinil in stimulant abusers: Low abuse potential
    • Malcolm R, Book S, Moak D, DeVane L, Czepowicz V. Clinical applications of modafinil in stimulant abusers: low abuse potential. Am J Addictions 2002; 11:247-249.
    • (2002) Am J Addictions , vol.11 , pp. 247-249
    • Malcolm, R.1    Book, S.2    Moak, D.3    DeVane, L.4    Czepowicz, V.5


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