메뉴 건너뛰기




Volumn 67, Issue 4, 2006, Pages 554-566

A systematic review of modafinil: Potential clinical uses and mechanisms of action

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA 1A ADRENERGIC RECEPTOR; DOPAMINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MODAFINIL; OREXIN;

EID: 33646768643     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v67n0406     Document Type: Review
Times cited : (333)

References (146)
  • 1
    • 2642638767 scopus 로고    scopus 로고
    • Randomized trial of modafinil for the treatment of pathological somnolence in narcolepsy
    • US Modafinil in Narcolepsy Multicenter Study Group. Randomized trial of modafinil for the treatment of pathological somnolence in narcolepsy. Ann Neurol 1998;43:88-97
    • (1998) Ann Neurol , vol.43 , pp. 88-97
  • 2
    • 0342545934 scopus 로고    scopus 로고
    • Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy
    • US Modafinil in Narcolepsy Multicenter Study Group. Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy. Neurology 2000;54:1166-1175
    • (2000) Neurology , vol.54 , pp. 1166-1175
  • 3
    • 0030816557 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of excessive daytime sleepiness in narcolepsy
    • Broughton RJ, Fleming JA, George CF, et al. Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of excessive daytime sleepiness in narcolepsy. Neurology 1997;49:444-451
    • (1997) Neurology , vol.49 , pp. 444-451
    • Broughton, R.J.1    Fleming, J.A.2    George, C.F.3
  • 4
    • 0028558347 scopus 로고
    • Modafinil: A double-blind multicentric study
    • Billiard M, Besset A, Montplaisir J, et al. Modafinil: a double-blind multicentric study. Sleep 1994;17(suppl 8):S107-112
    • (1994) Sleep , vol.17 , Issue.SUPPL. 8
    • Billiard, M.1    Besset, A.2    Montplaisir, J.3
  • 5
    • 0037273644 scopus 로고    scopus 로고
    • Narcolepsy in the older adult: Epidemiology, diagnosis and management
    • Chakravorty SS, Rye DB. Narcolepsy in the older adult: epidemiology, diagnosis and management. Drugs Aging 2003;20:361-376
    • (2003) Drugs Aging , vol.20 , pp. 361-376
    • Chakravorty, S.S.1    Rye, D.B.2
  • 6
    • 0037220288 scopus 로고    scopus 로고
    • Modafinil: Pharmacology and therapeutic perspectives
    • Billiard M. Modafinil: pharmacology and therapeutic perspectives [in French]. Rev Neurol (Paris) 2003;159:122-125
    • (2003) Rev Neurol (Paris) , vol.159 , pp. 122-125
    • Billiard, M.1
  • 7
    • 0031974267 scopus 로고    scopus 로고
    • Modafinil: A novel stimulant for the treatment of narcolepsy
    • Scammell TE, Matheson J. Modafinil: a novel stimulant for the treatment of narcolepsy. Expert Opin Investig Drags 1998;7:99-112
    • (1998) Expert Opin Investig Drags , vol.7 , pp. 99-112
    • Scammell, T.E.1    Matheson, J.2
  • 8
    • 0033605438 scopus 로고    scopus 로고
    • Modafinil for narcolepsy
    • Modafinil for narcolepsy. Med Lett Drugs Ther 1999;41:30-31
    • (1999) Med Lett Drugs Ther , vol.41 , pp. 30-31
  • 9
    • 23044480500 scopus 로고    scopus 로고
    • Modafinil for excessive sleepiness associated with shift-work sleep disorder
    • Czeisler CA, Walsh JK, Roth T, et al. Modafinil for excessive sleepiness associated with shift-work sleep disorder. N Engl J Med 2005;353:476-486
    • (2005) N Engl J Med , vol.353 , pp. 476-486
    • Czeisler, C.A.1    Walsh, J.K.2    Roth, T.3
  • 10
    • 24944505501 scopus 로고    scopus 로고
    • Modafinil: A review of its use in excessive sleepiness associated with obstructive sleep apnoea/hypopnoea syndrome and shift work sleep disorder
    • Keating GM, Raffin MJ. Modafinil: a review of its use in excessive sleepiness associated with obstructive sleep apnoea/hypopnoea syndrome and shift work sleep disorder. CNS Drugs 2005;19:785-803
    • (2005) CNS Drugs , vol.19 , pp. 785-803
    • Keating, G.M.1    Raffin, M.J.2
  • 11
    • 16844378038 scopus 로고    scopus 로고
    • Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea syndrome
    • Black JE, Hirshkowitz M. Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea syndrome. Sleep 2005;28:464-471
    • (2005) Sleep , vol.28 , pp. 464-471
    • Black, J.E.1    Hirshkowitz, M.2
  • 12
    • 0347624396 scopus 로고    scopus 로고
    • Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: A 12-week, open-label study
    • Schwartz JR, Hirshkowitz M, Erman MK, et al. Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea: a 12-week, open-label study. Chest 2003;124:2192-2199
    • (2003) Chest , vol.124 , pp. 2192-2199
    • Schwartz, J.R.1    Hirshkowitz, M.2    Erman, M.K.3
  • 13
    • 0035509118 scopus 로고    scopus 로고
    • Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea
    • Pack AI, Black JE, Schwartz JR, et al. Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea. Am J Respir Crit Care Med 2001;164:1675-1681
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1675-1681
    • Pack, A.I.1    Black, J.E.2    Schwartz, J.R.3
  • 14
    • 0035057580 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hypopnea syndrome
    • Kingshott RN, Vennelle M, Coleman EL, et al. Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med 2001;163:918-923
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 918-923
    • Kingshott, R.N.1    Vennelle, M.2    Coleman, E.L.3
  • 15
    • 85039330518 scopus 로고    scopus 로고
    • US Food and Drug Administration, Provigil Consumer Information. Available at: http://www.fda.gov/cder/consumerinfo/druginfo/provigil.htm. Accessibility verified March 2, 2006
    • Provigil Consumer Information
  • 16
    • 0028876379 scopus 로고
    • Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice
    • Simon P, Hemet C, Ramassamy C, et al. Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice. Eur Neuropsychopharmacol 1995;5:509-514
    • (1995) Eur Neuropsychopharmacol , vol.5 , pp. 509-514
    • Simon, P.1    Hemet, C.2    Ramassamy, C.3
  • 17
    • 0034891978 scopus 로고    scopus 로고
    • Off-label uses of modafinil [letter]
    • Teitelman E. Off-label uses of modafinil [letter]. Am J Psychiatry 2001;158:1341
    • (2001) Am J Psychiatry , vol.158 , pp. 1341
    • Teitelman, E.1
  • 18
    • 0026675087 scopus 로고
    • Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the cat
    • Lin JS, Roussel B, Akaoka H, et al. Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the cat. Brain Res 1992;591:319-326
    • (1992) Brain Res , vol.591 , pp. 319-326
    • Lin, J.S.1    Roussel, B.2    Akaoka, H.3
  • 19
    • 0035283399 scopus 로고    scopus 로고
    • Dopaminergic role in stimulant-induced wakefulness
    • Wisor JP, Nishino S, Sora I, et al. Dopaminergic role in stimulant-induced wakefulness. J Neurosci 2001;21:1787-1794
    • (2001) J Neurosci , vol.21 , pp. 1787-1794
    • Wisor, J.P.1    Nishino, S.2    Sora, I.3
  • 20
    • 25644454411 scopus 로고    scopus 로고
    • What are the dangers of methamphetamine?
    • Miller MC. What are the dangers of methamphetamine? Harv Ment Health Lett 2005;22:8
    • (2005) Harv Ment Health Lett , vol.22 , pp. 8
    • Miller, M.C.1
  • 21
    • 0037114067 scopus 로고    scopus 로고
    • 1B-adrenoceptors in modafinil-induced behavioral activity
    • 1B- adrenoceptors in modafinil-induced behavioral activity. Synapse 2002;46:269-270
    • (2002) Synapse , vol.46 , pp. 269-270
    • Stone, E.A.1    Cotecchia, S.2    Lin, Y.3
  • 22
    • 0036830478 scopus 로고    scopus 로고
    • Stress-induced subsensitivity to modafinil and its prevention by corticosteroids
    • Stone EA, Lin Y, Suckow RF, et al. Stress-induced subsensitivity to modafinil and its prevention by corticosteroids. Pharmacol Biochem Behav 2002;73:971-978
    • (2002) Pharmacol Biochem Behav , vol.73 , pp. 971-978
    • Stone, E.A.1    Lin, Y.2    Suckow, R.F.3
  • 23
    • 0029619294 scopus 로고
    • Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs
    • Shelton J, Nishino S, Vaught J, et al. Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs. Sleep 1995;18:817-826
    • (1995) Sleep , vol.18 , pp. 817-826
    • Shelton, J.1    Nishino, S.2    Vaught, J.3
  • 24
    • 0024425142 scopus 로고
    • The use of c-fos as a metabolic marker in neuronal pathway tracing
    • Dragunow M, Faull R. The use of c-fos as a metabolic marker in neuronal pathway tracing. J Neurosci Methods 1989;29:261-265
    • (1989) J Neurosci Methods , vol.29 , pp. 261-265
    • Dragunow, M.1    Faull, R.2
  • 25
    • 0030477691 scopus 로고    scopus 로고
    • Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat
    • Lin JS, Hou Y, Jouvet M. Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat. Proc Natl Acad Sci U S A 1996;93:14128-14133
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14128-14133
    • Lin, J.S.1    Hou, Y.2    Jouvet, M.3
  • 26
    • 0034668848 scopus 로고    scopus 로고
    • Hypothalamic arousal regions are activated during modafinil-induced wakefulness
    • Scammell TE, Estabrooke IV, McCarthy MT, et al. Hypothalamic arousal regions are activated during modafinil-induced wakefulness. J Neurosci 2000;20:8620-8628
    • (2000) J Neurosci , vol.20 , pp. 8620-8628
    • Scammell, T.E.1    Estabrooke, I.V.2    McCarthy, M.T.3
  • 27
    • 0032579408 scopus 로고    scopus 로고
    • Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil
    • Engber TM, Koury EJ, Dennis SA, et al. Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil. Neurosci Lett 1998;241:95-98
    • (1998) Neurosci Lett , vol.241 , pp. 95-98
    • Engber, T.M.1    Koury, E.J.2    Dennis, S.A.3
  • 28
    • 0031574307 scopus 로고    scopus 로고
    • Modafinil: An antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake Mockers
    • Ferraro L, Antonelli T, O'Connor WT, et al. Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake Mockers. Biol Psychiatry 1997;42:1181-1183
    • (1997) Biol Psychiatry , vol.42 , pp. 1181-1183
    • Ferraro, L.1    Antonelli, T.2    O'Connor, W.T.3
  • 30
    • 18344417904 scopus 로고    scopus 로고
    • The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism
    • Ferraro L, Tanganelli S, O'Connor WT, et al. The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism. Eur J Pharmacol 1996;306:33-39
    • (1996) Eur J Pharmacol , vol.306 , pp. 33-39
    • Ferraro, L.1    Tanganelli, S.2    O'Connor, W.T.3
  • 31
    • 0030573001 scopus 로고    scopus 로고
    • The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: Possible involvement of the serotonergic 5-HT3 receptor
    • Ferraro L, Tanganelli S, O'Connor WT, et al. The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor. Neurosci Lett 1996;220:5-8
    • (1996) Neurosci Lett , vol.220 , pp. 5-8
    • Ferraro, L.1    Tanganelli, S.2    O'Connor, W.T.3
  • 32
    • 0030875892 scopus 로고    scopus 로고
    • The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus
    • Ferraro L, Antonelli T, O'Connor WT, et al. The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus. Neuroreport 1997;8:2883-2887
    • (1997) Neuroreport , vol.8 , pp. 2883-2887
    • Ferraro, L.1    Antonelli, T.2    O'Connor, W.T.3
  • 33
    • 0033555585 scopus 로고    scopus 로고
    • Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus
    • Perez de la Mora M, Aguilar-Garcia A, Ramon-Frias T, et al. Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus. Neurosci Lett 1999;259:181-185
    • (1999) Neurosci Lett , vol.259 , pp. 181-185
    • Perez De La Mora, M.1    Aguilar-Garcia, A.2    Ramon-Frias, T.3
  • 34
    • 0033529520 scopus 로고    scopus 로고
    • The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
    • Lin L, Faraco J, Li R, et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999;98:365-376
    • (1999) Cell , vol.98 , pp. 365-376
    • Lin, L.1    Faraco, J.2    Li, R.3
  • 35
    • 0037137682 scopus 로고    scopus 로고
    • Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system
    • Li Y, Gao XB, Sakurai T, et al. Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron 2002;36:1169-1181
    • (2002) Neuron , vol.36 , pp. 1169-1181
    • Li, Y.1    Gao, X.B.2    Sakurai, T.3
  • 36
    • 0242643550 scopus 로고    scopus 로고
    • Wake-related activity of tuberomammillary neurons in rats
    • Ko EM, Estabrooke IV, McCarthy M. et al. Wake-related activity of tuberomammillary neurons in rats. Brain Res 2003;992:220-226
    • (2003) Brain Res , vol.992 , pp. 220-226
    • Ko, E.M.1    Estabrooke, I.V.2    McCarthy, M.3
  • 37
    • 0035859825 scopus 로고    scopus 로고
    • Arousal effect of orexin a depends on activation of the histaminergic system
    • Huang ZL, Qu WM, Li WD, et al. Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci U S A 2001;98:9965-9970
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9965-9970
    • Huang, Z.L.1    Qu, W.M.2    Li, W.D.3
  • 38
    • 0037457359 scopus 로고    scopus 로고
    • Modafinil increases histamine release in the anterior hypothalamus of rats
    • Ishizuka T, Sakamoto Y, Sakurai T, et al. Modafinil increases histamine release in the anterior hypothalamus of rats. Neurosci Lett 2003;339:143-146
    • (2003) Neurosci Lett , vol.339 , pp. 143-146
    • Ishizuka, T.1    Sakamoto, Y.2    Sakurai, T.3
  • 39
    • 0034048206 scopus 로고    scopus 로고
    • In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil
    • Robertson P, DeCory HH, Madan A, et al. In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil. Drug Metab Dispos 2000;28:664-671
    • (2000) Drug Metab Dispos , vol.28 , pp. 664-671
    • Robertson, P.1    Decory, H.H.2    Madan, A.3
  • 41
    • 4444353742 scopus 로고    scopus 로고
    • Concomitant use of modafinil and tranylcypromine in a patient with narcolepsy: A case report
    • Clemons WE, Makela E, Young J. Concomitant use of modafinil and tranylcypromine in a patient with narcolepsy: a case report. Sleep Med 2004;5:509-511
    • (2004) Sleep Med , vol.5 , pp. 509-511
    • Clemons, W.E.1    Makela, E.2    Young, J.3
  • 42
    • 4444249123 scopus 로고    scopus 로고
    • Modafinil augmentation of phenelzine for residual fatigue in dysthymia [letter]
    • Ashton AK. Modafinil augmentation of phenelzine for residual fatigue in dysthymia [letter]. Am J Psychiatry 2004;161:1716-1717
    • (2004) Am J Psychiatry , vol.161 , pp. 1716-1717
    • Ashton, A.K.1
  • 43
    • 0029565951 scopus 로고
    • Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work, 2: Effects on two nights of recovery sleep
    • Buguet A, Montmayeur A, Pigeau R, et al. Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work, 2: effects on two nights of recovery sleep. J Sleep Res 1995;4:229-241
    • (1995) J Sleep Res , vol.4 , pp. 229-241
    • Buguet, A.1    Montmayeur, A.2    Pigeau, R.3
  • 45
    • 0034072996 scopus 로고    scopus 로고
    • Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat
    • Lin JS, Gervasoni D, Hou Y, et al. Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat. J Sleep Res 2000;9:89-96
    • (2000) J Sleep Res , vol.9 , pp. 89-96
    • Lin, J.S.1    Gervasoni, D.2    Hou, Y.3
  • 46
    • 4143088220 scopus 로고    scopus 로고
    • Modafinil: Preclinical, clinical, and post-marketing surveillance: A review of abuse liability issues
    • Myrick H, Malcolm R, Taylor B, et al. Modafinil: preclinical, clinical, and post-marketing surveillance: a review of abuse liability issues. Ann Clin Psychiatry 2004;16:101-109
    • (2004) Ann Clin Psychiatry , vol.16 , pp. 101-109
    • Myrick, H.1    Malcolm, R.2    Taylor, B.3
  • 47
    • 0036235778 scopus 로고    scopus 로고
    • Acute behavioral and physiological effects of modafinil in drug abusers
    • Rush CR, Kelly TH, Hays LR, et al. Acute behavioral and physiological effects of modafinil in drug abusers. Behav Pharmacol 2002;13:105-115
    • (2002) Behav Pharmacol , vol.13 , pp. 105-115
    • Rush, C.R.1    Kelly, T.H.2    Hays, L.R.3
  • 48
    • 22144491932 scopus 로고    scopus 로고
    • Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system
    • Nishino SS, Kanbayashi TT. Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system. Sleep Med Rev 2005;9:269-310
    • (2005) Sleep Med Rev , vol.9 , pp. 269-310
    • Nishino, S.S.1    Kanbayashi, T.T.2
  • 49
    • 85039319797 scopus 로고    scopus 로고
    • US Food and Drug Administration, Center for Drug Evaluation and Research. Provigil (Modafinil) Tablets Approval Package. Available at: http://www.fda.gov/cder/foi/nda/98/020717A_Provigil.htm. Accessibility verified March 2, 2006
    • Provigil (Modafinil) Tablets Approval Package
  • 50
    • 0001609188 scopus 로고    scopus 로고
    • Long-term efficacy and safety of modafinil (Provigil®) for the treatment of excessive daytime sleepiness associated with narcolepsy
    • Mitler MM, Harsh J, Hirshkowitz M, et al. Long-term efficacy and safety of modafinil (Provigil®) for the treatment of excessive daytime sleepiness associated with narcolepsy. Sleep Med 2000;1:231-243
    • (2000) Sleep Med , vol.1 , pp. 231-243
    • Mitler, M.M.1    Harsh, J.2    Hirshkowitz, M.3
  • 51
    • 0012170492 scopus 로고    scopus 로고
    • Efficacy and safety profiles of modafinil maintained during long-term (40 and 88 weeks) treatment of excessive daytime sleepiness associated with narcolepsy
    • Emsellem H. Efficacy and safety profiles of modafinil maintained during long-term (40 and 88 weeks) treatment of excessive daytime sleepiness associated with narcolepsy. Neurology 2000;54(7, suppl 3):A29-A30
    • (2000) Neurology , vol.54 , Issue.7 SUPPL. 3
    • Emsellem, H.1
  • 52
    • 0344880888 scopus 로고    scopus 로고
    • Long-term (136 weeks) safety and efficacy of modafinil for the treatment of excessive daytime sleepiness associated with narcolepsy
    • Hirshkowitz M. Long-term (136 weeks) safety and efficacy of modafinil for the treatment of excessive daytime sleepiness associated with narcolepsy. Sleep 2001;24(supplement):A329
    • (2001) Sleep , vol.24 , Issue.SUPPL.
    • Hirshkowitz, M.1
  • 53
    • 0029899133 scopus 로고    scopus 로고
    • Use of modafinil in the treatment of narcolepsy: A long term follow-up study
    • Besset A, Chetrit M, Carlander B, et al. Use of modafinil in the treatment of narcolepsy: a long term follow-up study. Neurophysiol Clin 1996;26:60-66
    • (1996) Neurophysiol Clin , vol.26 , pp. 60-66
    • Besset, A.1    Chetrit, M.2    Carlander, B.3
  • 54
    • 5044223398 scopus 로고    scopus 로고
    • Orcadian rhythm disorders
    • Reid KJ, Zee PC. Orcadian rhythm disorders. Semin Neurol 2004;24:315-325
    • (2004) Semin Neurol , vol.24 , pp. 315-325
    • Reid, K.J.1    Zee, P.C.2
  • 55
    • 3543059474 scopus 로고    scopus 로고
    • Modafinil improves quality of life and is well tolerated in shift work sleep disorder
    • Rosenberg R, Erman M, Emsellem H, et al. Modafinil improves quality of life and is well tolerated in shift work sleep disorder. Sleep 2003;26: A112-A113
    • (2003) Sleep , vol.26
    • Rosenberg, R.1    Erman, M.2    Emsellem, H.3
  • 56
    • 85039334011 scopus 로고    scopus 로고
    • Patient quality of life and tolerability of long-term modafinil in shift work sleep disorder
    • June 5-10, Philadelphia, Pa
    • Erman M. Patient quality of life and tolerability of long-term modafinil in shift work sleep disorder. Presented at Associated Professional Sleep Societies; June 5-10, 2004; Philadelphia, Pa
    • (2004) Associated Professional Sleep Societies
    • Erman, M.1
  • 57
    • 14644429105 scopus 로고    scopus 로고
    • Obstructive sleep apnea syndromes
    • Collop N. Obstructive sleep apnea syndromes. Semin Respir Crit Care Med 2005;26:13-24
    • (2005) Semin Respir Crit Care Med , vol.26 , pp. 13-24
    • Collop, N.1
  • 58
    • 0019420178 scopus 로고
    • Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares
    • Sullivan C, Issa F, Berthon-Jones M, et al. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet 1981;1:862-865
    • (1981) Lancet , vol.1 , pp. 862-865
    • Sullivan, C.1    Issa, F.2    Berthon-Jones, M.3
  • 59
    • 0037240937 scopus 로고    scopus 로고
    • Fatigue in multiple sclerosis: Definition, pathophysiology and treatment
    • Krupp LB. Fatigue in multiple sclerosis: definition, pathophysiology and treatment. CNS Drugs 2003;17:225-234
    • (2003) CNS Drugs , vol.17 , pp. 225-234
    • Krupp, L.B.1
  • 62
    • 0026741457 scopus 로고
    • 'Fatigue' in patients with multiple sclerosis: Motor pathway conduction and event-related potentials
    • Sandroni P, Walker C, Starr A. 'Fatigue' in patients with multiple sclerosis: motor pathway conduction and event-related potentials. Arch Neurol 1992;49:517-524
    • (1992) Arch Neurol , vol.49 , pp. 517-524
    • Sandroni, P.1    Walker, C.2    Starr, A.3
  • 63
    • 0028864415 scopus 로고
    • Evidence of an abnormal intramuscular component of fatigue in multiple sclerosis
    • Sharma KR, Kent-Braun J, Mynhier MA, et al. Evidence of an abnormal intramuscular component of fatigue in multiple sclerosis. Muscle Nerve 1995;18:1403-1411
    • (1995) Muscle Nerve , vol.18 , pp. 1403-1411
    • Sharma, K.R.1    Kent-Braun, J.2    Mynhier, M.A.3
  • 64
    • 0036038978 scopus 로고    scopus 로고
    • Modafinil in treatment of fatigue in multiple sclerosis: Results of an open-label study
    • Zifko UA, Rupp M, Schwarz S, et al. Modafinil in treatment of fatigue in multiple sclerosis: results of an open-label study. J Neurol 2002;249:983-987
    • (2002) J Neurol , vol.249 , pp. 983-987
    • Zifko, U.A.1    Rupp, M.2    Schwarz, S.3
  • 65
    • 0038518191 scopus 로고    scopus 로고
    • Fatigue associated with multiple sclerosis: Diagnosis, impact and management
    • Bakshi R. Fatigue associated with multiple sclerosis: diagnosis, impact and management. Mult Scler 2003;9:219-227
    • (2003) Mult Scler , vol.9 , pp. 219-227
    • Bakshi, R.1
  • 66
    • 0036152780 scopus 로고    scopus 로고
    • Efficacy and safety of modafinil (Provigil) for the treatment of fatigue in multiple sclerosis: A two centre phase 2 study
    • Rammohan KW, Rosenberg JH, Lynn DJ, et al. Efficacy and safety of modafinil (Provigil) for the treatment of fatigue in multiple sclerosis: a two centre phase 2 study. J Neurol Neurosurg Psychiatry 2002;72:179-183
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 179-183
    • Rammohan, K.W.1    Rosenberg, J.H.2    Lynn, D.J.3
  • 67
    • 20144389425 scopus 로고    scopus 로고
    • Modafinil for fatigue in MS: A randomized placebo-controlled double-blind study
    • Stankoff B, Waubant E, Confavreux C, et al. Modafinil for fatigue in MS: a randomized placebo-controlled double-blind study. Neurology 2005;64:1139-1143
    • (2005) Neurology , vol.64 , pp. 1139-1143
    • Stankoff, B.1    Waubant, E.2    Confavreux, C.3
  • 68
    • 0141562507 scopus 로고    scopus 로고
    • Sleepiness and unintended sleep in Parkinson's disease
    • Rye DB. Sleepiness and unintended sleep in Parkinson's disease. Curr Treat Options Neurol 2003;5:231-239
    • (2003) Curr Treat Options Neurol , vol.5 , pp. 231-239
    • Rye, D.B.1
  • 69
    • 0036112840 scopus 로고    scopus 로고
    • Treatment of excessive daytime sleepiness in patients with Parkinson's disease with modafinil
    • Nieves AV, Lang AE. Treatment of excessive daytime sleepiness in patients with Parkinson's disease with modafinil. Clin Neuropharmacol 2002;25:111-114
    • (2002) Clin Neuropharmacol , vol.25 , pp. 111-114
    • Nieves, A.V.1    Lang, A.E.2
  • 70
    • 0037355884 scopus 로고    scopus 로고
    • Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease
    • Adler CH, Caviness JN, Hentz JG, et al. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov Disord 2003;18:287-293
    • (2003) Mov Disord , vol.18 , pp. 287-293
    • Adler, C.H.1    Caviness, J.N.2    Hentz, J.G.3
  • 71
    • 0037114678 scopus 로고    scopus 로고
    • Modafinil for the treatment of daytime sleepiness in Parkinson's disease: A double-blind, randomized, crossover, placebo-controlled polygraphic trial
    • Hogl B, Saletu M, Brandauer E, et al. Modafinil for the treatment of daytime sleepiness in Parkinson's disease: a double-blind, randomized, crossover, placebo-controlled polygraphic trial. Sleep 2002;25:905-909
    • (2002) Sleep , vol.25 , pp. 905-909
    • Hogl, B.1    Saletu, M.2    Brandauer, E.3
  • 72
    • 28144435110 scopus 로고    scopus 로고
    • Modafinil for daytime somnolence in Parkinson's disease: Double blind, placebo controlled parallel trial
    • Ondo WG, Fayle R, Atassi F, et al. Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial. J Neurol Neurosurg Psychiatry 2005;76:1636-1639
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1636-1639
    • Ondo, W.G.1    Fayle, R.2    Atassi, F.3
  • 73
    • 0034728235 scopus 로고    scopus 로고
    • Chronic fatigue syndrome
    • Reid S, Chalder T, Cleare A, et al. Chronic fatigue syndrome. BMJ 2000;320:292-296
    • (2000) BMJ , vol.320 , pp. 292-296
    • Reid, S.1    Chalder, T.2    Cleare, A.3
  • 74
    • 0035913570 scopus 로고    scopus 로고
    • Interventions for the treatment and management of chronic fatigue syndrome: A systematic review [Erratum in JAMA 2002;287:1401]
    • Whiting P, Bagnall AM, Sowden AJ, et al. Interventions for the treatment and management of chronic fatigue syndrome: a systematic review [Erratum in JAMA 2002;287:1401]. JAMA 2001;286:1360-1368
    • (2001) JAMA , vol.286 , pp. 1360-1368
    • Whiting, P.1    Bagnall, A.M.2    Sowden, A.J.3
  • 75
    • 0742289911 scopus 로고    scopus 로고
    • Recovery from chronic fatigue syndrome with modafinil
    • Turkington D, Hedwat D, Rider I, et al. Recovery from chronic fatigue syndrome with modafinil. Hum Psychopharmacol 2004;19:63-64
    • (2004) Hum Psychopharmacol , vol.19 , pp. 63-64
    • Turkington, D.1    Hedwat, D.2    Rider, I.3
  • 76
    • 27644571512 scopus 로고    scopus 로고
    • Chronic treatment with modafinil may not be beneficial in patients with chronic fatigue syndrome
    • Randall DC, Cafferty FH, Shneerson JM, et al. Chronic treatment with modafinil may not be beneficial in patients with chronic fatigue syndrome. J Psychopharmacol 2005;19:647-660
    • (2005) J Psychopharmacol , vol.19 , pp. 647-660
    • Randall, D.C.1    Cafferty, F.H.2    Shneerson, J.M.3
  • 77
    • 30344463306 scopus 로고    scopus 로고
    • Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients
    • Chan KM, Strohschein FJ, Rydz D, et al. Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients. Muscle Nerve 2006;33:138-141
    • (2006) Muscle Nerve , vol.33 , pp. 138-141
    • Chan, K.M.1    Strohschein, F.J.2    Rydz, D.3
  • 78
    • 13744250926 scopus 로고    scopus 로고
    • Modafinil treatment for fatigue in HIV+ patients: A pilot study
    • Rabkin JG, McElhiney MC, Rabkin R, et al. Modafinil treatment for fatigue in HIV+ patients: a pilot study. J Clin Psychiatry 2004;65:1688-1695
    • (2004) J Clin Psychiatry , vol.65 , pp. 1688-1695
    • Rabkin, J.G.1    McElhiney, M.C.2    Rabkin, R.3
  • 79
    • 19144369659 scopus 로고    scopus 로고
    • Does modafinil have the potential to improve disrupted sleep patterns in patients with dementia?
    • Howcroft DJ, Jones RW. Does modafinil have the potential to improve disrupted sleep patterns in patients with dementia? [letter] Int J Geriatr Psychiatry 2005;20:492-495
    • (2005) Int J Geriatr Psychiatry , vol.20 , pp. 492-495
    • Howcroft, D.J.1    Jones, R.W.2
  • 80
    • 0035200592 scopus 로고    scopus 로고
    • Effect of modafinil on fatigue associated with neurological illnesses
    • Cochran JW. Effect of modafinil on fatigue associated with neurological illnesses. J Chronic Fatigue Syndrome 2001;8:65-70
    • (2001) J Chronic Fatigue Syndrome , vol.8 , pp. 65-70
    • Cochran, J.W.1
  • 82
    • 25444499698 scopus 로고    scopus 로고
    • Modafinil for the treatment of fatigue in primary biliary cirrhosis
    • Kaplan MM, Bonis PA. Modafinil for the treatment of fatigue in primary biliary cirrhosis [letter]. Ann Intern Med 2005;143:546-547
    • (2005) Ann Intern Med , vol.143 , pp. 546-547
    • Kaplan, M.M.1    Bonis, P.A.2
  • 83
    • 13444274616 scopus 로고    scopus 로고
    • Modafinil to treat fatigue in amyotrophic lateral sclerosis: An open label pilot study
    • Carter GT, Weiss MD, Lou JS, et al. Modafinil to treat fatigue in amyotrophic lateral sclerosis: an open label pilot study. Am J Hosp Palliat Care 2005;22:55-59
    • (2005) Am J Hosp Palliat Care , vol.22 , pp. 55-59
    • Carter, G.T.1    Weiss, M.D.2    Lou, J.S.3
  • 84
    • 0034447110 scopus 로고    scopus 로고
    • Enhancement of noradrenergic neural transmission: An effective therapy of myasthenia gravis: A report on 52 consecutive patients
    • Lechin F, van der Dijs B, Pardey-Maldonado B, et al. Enhancement of noradrenergic neural transmission: an effective therapy of myasthenia gravis: a report on 52 consecutive patients. J Med 2000;31:333-361
    • (2000) J Med , vol.31 , pp. 333-361
    • Lechin, F.1    Van Der Dijs, B.2    Pardey-Maldonado, B.3
  • 85
    • 0842278733 scopus 로고    scopus 로고
    • Modafinil treatment of excessive sedation associated with divalproex sodium
    • Berigan T. Modafinil treatment of excessive sedation associated with divalproex sodium [letter]. Can J Psychiatry 2004;49:72-73
    • (2004) Can J Psychiatry , vol.49 , pp. 72-73
    • Berigan, T.1
  • 86
    • 33646761433 scopus 로고    scopus 로고
    • Modafinil treatment of excessive daytime sedation and fatigue associated with topiramate
    • Berigan TR. Modafinil treatment of excessive daytime sedation and fatigue associated with topiramate. Prim Care Companion J Clin Psychiatry 2002;4:249-250
    • (2002) Prim Care Companion J Clin Psychiatry , vol.4 , pp. 249-250
    • Berigan, T.R.1
  • 87
    • 5444237020 scopus 로고    scopus 로고
    • An open-label study of adjunctive modafinil in patients with sedation related to serotonergic antidepressant therapy
    • Schwartz TL, Azhar N, Cole K, et al. An open-label study of adjunctive modafinil in patients with sedation related to serotonergic antidepressant therapy. J Clin Psychiatry 2004;65:1223-1227
    • (2004) J Clin Psychiatry , vol.65 , pp. 1223-1227
    • Schwartz, T.L.1    Azhar, N.2    Cole, K.3
  • 88
    • 22744432869 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications
    • Sevy S, Rosenthal MH, Alvir J, et al. Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications. J Clin Psychiatry 2005;66:839-843
    • (2005) J Clin Psychiatry , vol.66 , pp. 839-843
    • Sevy, S.1    Rosenthal, M.H.2    Alvir, J.3
  • 89
    • 0037696255 scopus 로고    scopus 로고
    • Three case reports of modafinil use in treating sedation induced by antipsychotic medications
    • Makela EH, Miller K, Cutlip WD II. Three case reports of modafinil use in treating sedation induced by antipsychotic medications [letter]. J Clin Psychiatry 2003;64:485-486
    • (2003) J Clin Psychiatry , vol.64 , pp. 485-486
    • Makela, E.H.1    Miller, K.2    Cutlip II, W.D.3
  • 90
    • 0036303309 scopus 로고    scopus 로고
    • Modafinil-associated clozapine toxicity
    • Dequardo JR. Modafinil-associated clozapine toxicity [letter]. Am J Psychiatry 2002;159:1243-1244
    • (2002) Am J Psychiatry , vol.159 , pp. 1243-1244
    • Dequardo, J.R.1
  • 91
    • 1642502596 scopus 로고    scopus 로고
    • Modafinil improves recovery after general anesthesia
    • table of contents
    • Larijani GE, Goldberg ME, Hojat M, et al. Modafinil improves recovery after general anesthesia. Anesth Analg 2004;98:976-981, table of contents
    • (2004) Anesth Analg , vol.98 , pp. 976-981
    • Larijani, G.E.1    Goldberg, M.E.2    Hojat, M.3
  • 92
    • 0026779077 scopus 로고
    • The use of methylphenidate in patients with incident cancer pain receiving regular opiates: A preliminary report
    • Bruera E, Fainsinger R, MacEachern T, et al. The use of methylphenidate in patients with incident cancer pain receiving regular opiates: a preliminary report. Pain 1992;50:75-77
    • (1992) Pain , vol.50 , pp. 75-77
    • Bruera, E.1    Fainsinger, R.2    MacEachern, T.3
  • 93
    • 0042132064 scopus 로고    scopus 로고
    • Modafinil treatment of opioid-induced sedation
    • Webster L, Andrews M, Stoddard G. Modafinil treatment of opioid-induced sedation. Pain Med 2003;4:135-140
    • (2003) Pain Med , vol.4 , pp. 135-140
    • Webster, L.1    Andrews, M.2    Stoddard, G.3
  • 94
    • 8744261926 scopus 로고    scopus 로고
    • Effect of modafinil on acute pain: A randomized double-blind crossover study
    • Taneja I, Bruehl S, Robertson D. Effect of modafinil on acute pain: a randomized double-blind crossover study. J Clin Pharmacol 2004;44:1425-1427
    • (2004) J Clin Pharmacol , vol.44 , pp. 1425-1427
    • Taneja, I.1    Bruehl, S.2    Robertson, D.3
  • 95
    • 24144481900 scopus 로고    scopus 로고
    • Mental health in the United States: Prevalence of diagnosis and medication treatment for attention-deficit/hyperactivity disorder: United States, 2003
    • Centers for Disease Control and Prevention. Mental health in the United States: prevalence of diagnosis and medication treatment for attention-deficit/hyperactivity disorder: United States, 2003. MMWR Morb Mortal Wkly R 2005;54:842-847
    • (2005) MMWR Morb Mortal Wkly R , vol.54 , pp. 842-847
  • 97
    • 0041347693 scopus 로고    scopus 로고
    • Attention deficit hyperactivity disorder: Guidelines for investigating efficacy of pharmacological intervention
    • Buitelaar JK, Montgomery SA, van Zwieten-Boot BJ. Attention deficit hyperactivity disorder: guidelines for investigating efficacy of pharmacological intervention. Eur Neuropsychopharmacol 2003;13:297-304
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. 297-304
    • Buitelaar, J.K.1    Montgomery, S.A.2    Van Zwieten-Boot, B.J.3
  • 98
    • 9544230671 scopus 로고    scopus 로고
    • Six-week, double-blind, placebo-controlled study of desipramine for adult attention deficit hyperactivity disorder
    • Wilens TE, Biederman J, Prince J, et al. Six-week, double-blind, placebo-controlled study of desipramine for adult attention deficit hyperactivity disorder. Am J Psychiatry 1996;153:1147-1153
    • (1996) Am J Psychiatry , vol.153 , pp. 1147-1153
    • Wilens, T.E.1    Biederman, J.2    Prince, J.3
  • 99
    • 0037768960 scopus 로고    scopus 로고
    • Atomoxetine: A selective noradrenaline reuptake inhibitor for the treatment of attention-deficit/hyperactivity disorder
    • Kratochvil CJ, Vaughan BS, Harrington MJ, et al. Atomoxetine: a selective noradrenaline reuptake inhibitor for the treatment of attention-deficit/ hyperactivity disorder. Expert Opin Pharmacother 2003;4:1165-1174
    • (2003) Expert Opin Pharmacother , vol.4 , pp. 1165-1174
    • Kratochvil, C.J.1    Vaughan, B.S.2    Harrington, M.J.3
  • 100
    • 16844387107 scopus 로고    scopus 로고
    • Bupropion XL in adults with attention-deficit/hyperactivity disorder: A randomized, placebo-controlled study
    • Wilens TE, Haight BR, Horrigan JP, et al. Bupropion XL in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled study. Biol Psychiatry 2005;57:793-801
    • (2005) Biol Psychiatry , vol.57 , pp. 793-801
    • Wilens, T.E.1    Haight, B.R.2    Horrigan, J.P.3
  • 101
    • 0034491316 scopus 로고    scopus 로고
    • Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults
    • Taylor FB, Russo J. Efficacy of modafinil compared to dextroamphetamine for the treatment of attention deficit hyperactivity disorder in adults. J Child Adolesc Psychopharmacol 2000;10:311-320
    • (2000) J Child Adolesc Psychopharmacol , vol.10 , pp. 311-320
    • Taylor, F.B.1    Russo, J.2
  • 102
    • 0142248344 scopus 로고    scopus 로고
    • Modafinil in children with attention-deficit hyperactivity disorder
    • Rugino TA, Samsock TC. Modafinil in children with attention-deficit hyperactivity disorder. Pediatr Neurol 2003;29:136-142
    • (2003) Pediatr Neurol , vol.29 , pp. 136-142
    • Rugino, T.A.1    Samsock, T.C.2
  • 103
    • 2342618897 scopus 로고    scopus 로고
    • Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder
    • Turner DC, Clark L, Dowson J, et al. Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder. Biol Psychiatry 2004;55:1031-1040
    • (2004) Biol Psychiatry , vol.55 , pp. 1031-1040
    • Turner, D.C.1    Clark, L.2    Dowson, J.3
  • 105
    • 33644680762 scopus 로고    scopus 로고
    • Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: Results of a randomized, double-blind, placebo-controlled, flexible-dose study
    • Biederman J, Swanson JM, Wigal SB, et al. Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, flexible-dose study. Pediatrics 2005;116:e777-e784
    • (2005) Pediatrics , vol.116
    • Biederman, J.1    Swanson, J.M.2    Wigal, S.B.3
  • 106
    • 16244395584 scopus 로고    scopus 로고
    • Daytime sleepiness and insomnia as correlates of depression
    • Fava M. Daytime sleepiness and insomnia as correlates of depression. J Clin Psychiatry 2004;65(suppl 16):27-32
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 16 , pp. 27-32
    • Fava, M.1
  • 107
    • 0037380690 scopus 로고    scopus 로고
    • An open-label trial of modafinil augmentation in patients with partial response to antidepressant therapy
    • Markovitz PJ, Wagner S. An open-label trial of modafinil augmentation in patients with partial response to antidepressant therapy [letter]. J Clin Psychopharmacol 2003;23:207-209
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 207-209
    • Markovitz, P.J.1    Wagner, S.2
  • 108
    • 0034078972 scopus 로고    scopus 로고
    • Modafinil augmentation of antidepressant treatment in depression
    • Menza MA, Kaufman KR, Castellanos A. Modafinil augmentation of antidepressant treatment in depression. J Clin Psychiatry 2000;61:378-381
    • (2000) J Clin Psychiatry , vol.61 , pp. 378-381
    • Menza, M.A.1    Kaufman, K.R.2    Castellanos, A.3
  • 109
    • 13844315590 scopus 로고    scopus 로고
    • A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness
    • Fava M, Thase ME, DeBattista C. A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness. J Clin Psychiatry 2005;66:85-93
    • (2005) J Clin Psychiatry , vol.66 , pp. 85-93
    • Fava, M.1    Thase, M.E.2    Debattista, C.3
  • 110
  • 111
    • 23844443454 scopus 로고    scopus 로고
    • A retrospective chart review of the effects of modafinil on depression as monotherapy and as adjunctive therapy
    • Price CS, Taylor FB. A retrospective chart review of the effects of modafinil on depression as monotherapy and as adjunctive therapy. Depress Anxiety 2005;21:149-153
    • (2005) Depress Anxiety , vol.21 , pp. 149-153
    • Price, C.S.1    Taylor, F.B.2
  • 112
    • 0036843811 scopus 로고    scopus 로고
    • Modafinil for social phobia and amphetamine dependence
    • Camacho A, Stein MB. Modafinil for social phobia and amphetamine dependence [letter]. Am J Psychiatry 2002;159:1947-1948
    • (2002) Am J Psychiatry , vol.159 , pp. 1947-1948
    • Camacho, A.1    Stein, M.B.2
  • 113
    • 0345707604 scopus 로고    scopus 로고
    • Modafinil for remitted bipolar depression with hypersomnia
    • Fernandes PP, Petty F. Modafinil for remitted bipolar depression with hypersomnia. Ann Pharmacother 2003;37:1807-1809
    • (2003) Ann Pharmacother , vol.37 , pp. 1807-1809
    • Fernandes, P.P.1    Petty, F.2
  • 114
    • 0030588648 scopus 로고    scopus 로고
    • Sleep loss, a possible factor in augmenting manic episode
    • Barbini B, Bertelli S, Colombo C, et al. Sleep loss, a possible factor in augmenting manic episode. Psychiatry Res 1996;65:121-125
    • (1996) Psychiatry Res , vol.65 , pp. 121-125
    • Barbini, B.1    Bertelli, S.2    Colombo, C.3
  • 115
    • 33646760054 scopus 로고    scopus 로고
    • Modafinil in the treatment of bipolar depression: A placebo-controlled study
    • Frye M, Grunze H, Suppes T, et al. Modafinil in the treatment of bipolar depression: a placebo-controlled study. Neuropsychopharmacology 2005;30(suppl 1):S111
    • (2005) Neuropsychopharmacology , vol.30 , Issue.SUPPL. 1
    • Frye, M.1    Grunze, H.2    Suppes, T.3
  • 116
    • 16844376505 scopus 로고    scopus 로고
    • Mania in a boy treated with modafinil for narcolepsy
    • Vorspan F, Warot D, Consoli A, et al. Mania in a boy treated with modafinil for narcolepsy [letter]. Am J Psychiatry 2005;162:813-814
    • (2005) Am J Psychiatry , vol.162 , pp. 813-814
    • Vorspan, F.1    Warot, D.2    Consoli, A.3
  • 117
    • 29144524574 scopus 로고    scopus 로고
    • Modafinil as an adjunctive treatment to sleep deprivation in depression [116]
    • Even C, Thuile J, Santos J, et al. Modafinil as an adjunctive treatment to sleep deprivation in depression [116]. J Psychiatry Neurosci 2005;30:432-433
    • (2005) J Psychiatry Neurosci , vol.30 , pp. 432-433
    • Even, C.1    Thuile, J.2    Santos, J.3
  • 118
    • 0037740740 scopus 로고    scopus 로고
    • Therapeutic use of sleep deprivation in depression
    • Giedke H, Schwarzler F. Therapeutic use of sleep deprivation in depression. Sleep Med Rev 2002;6:361-377
    • (2002) Sleep Med Rev , vol.6 , pp. 361-377
    • Giedke, H.1    Schwarzler, F.2
  • 119
    • 0346461622 scopus 로고    scopus 로고
    • Glutamatergic agents for cocaine dependence
    • Dackis C, O'Brien C. Glutamatergic agents for cocaine dependence. Ann N Y Acad Sci 2003;1003:328-345
    • (2003) Ann N Y Acad Sci , vol.1003 , pp. 328-345
    • Dackis, C.1    O'Brien, C.2
  • 120
    • 11144292693 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of modafinil for cocaine dependence
    • Dackis CA, Kampman KM, Lynch KG, et al. A double-blind, placebo-controlled trial of modafinil for cocaine dependence. Neuropsychopharmacology 2005;30:205-211
    • (2005) Neuropsychopharmacology , vol.30 , pp. 205-211
    • Dackis, C.A.1    Kampman, K.M.2    Lynch, K.G.3
  • 121
    • 1442275580 scopus 로고    scopus 로고
    • Benefits of adjunct modafinil in an open-label, pilot study in patients with schizophrenia
    • Rosenthal MH, Bryant SL. Benefits of adjunct modafinil in an open-label, pilot study in patients with schizophrenia. Clin Neuropharmacol 2004;27:38-43
    • (2004) Clin Neuropharmacol , vol.27 , pp. 38-43
    • Rosenthal, M.H.1    Bryant, S.L.2
  • 122
    • 2942685608 scopus 로고    scopus 로고
    • Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia
    • Turner DC, Clark L, Pomarol-Clotet E, et al. Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia. Neuropsychopharmacology 2004;29:1363-1373
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1363-1373
    • Turner, D.C.1    Clark, L.2    Pomarol-Clotet, E.3
  • 123
    • 22044445930 scopus 로고    scopus 로고
    • Modafinil-associated weight loss in a clozapine-treated schizoaffective disorder patient
    • Henderson DC, Louie PM, Koul P, et al. Modafinil-associated weight loss in a clozapine-treated schizoaffective disorder patient. Ann Clin Psychiatry 2005;17:95-97
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 95-97
    • Henderson, D.C.1    Louie, P.M.2    Koul, P.3
  • 124
    • 33646791990 scopus 로고    scopus 로고
    • A double-blind placebo controlled trial of modafinil for negative symptoms in schizophrenia, 2005
    • Pierre J, Pelioan J, Wirshing D, et al. A double-blind placebo controlled trial of modafinil for negative symptoms in schizophrenia, 2005. Neuropsychopharmacology 2005;30(suppl 1):S207
    • (2005) Neuropsychopharmacology , vol.30 , Issue.SUPPL. 1
    • Pierre, J.1    Pelioan, J.2    Wirshing, D.3
  • 126
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2000
    • Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-1727
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3
  • 127
    • 1542298961 scopus 로고    scopus 로고
    • Wake-promoting agents with different mechanisms of action: Comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity
    • Makris AP, Rush CR, Frederich RC, et al. Wake-promoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity. Appetite 2004;42:185-195
    • (2004) Appetite , vol.42 , pp. 185-195
    • Makris, A.P.1    Rush, C.R.2    Frederich, R.C.3
  • 128
    • 0036018865 scopus 로고    scopus 로고
    • Use of modafinil in spastic cerebral palsy
    • Hurst DL, Lajara-Nanson W. Use of modafinil in spastic cerebral palsy. J Child Neurol 2002;17:169-172
    • (2002) J Child Neurol , vol.17 , pp. 169-172
    • Hurst, D.L.1    Lajara-Nanson, W.2
  • 129
    • 13444271922 scopus 로고    scopus 로고
    • Retrospective review of modafinil use for cerebral palsy
    • Hurst DL, Lajara-Nanson WA, Dinakar P, et al. Retrospective review of modafinil use for cerebral palsy. J Child Neurol 2004;19:948-951
    • (2004) J Child Neurol , vol.19 , pp. 948-951
    • Hurst, D.L.1    Lajara-Nanson, W.A.2    Dinakar, P.3
  • 131
    • 16444387020 scopus 로고    scopus 로고
    • Modafinil in sports: Ethical considerations
    • Kaufman KR. Modafinil in sports: ethical considerations. Br J Sports Med 2005;39:241-244
    • (2005) Br J Sports Med , vol.39 , pp. 241-244
    • Kaufman, K.R.1
  • 132
    • 16444375989 scopus 로고    scopus 로고
    • World Anti-Doping Agency. The 2005 Prohibited List: International Standard. Available at: http://www.wada-ama.org/rtecontent/document/list_2005. pdf. Accessibility verified March 2, 2006
    • The 2005 Prohibited List: International Standard
  • 134
    • 1542300280 scopus 로고    scopus 로고
    • The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers
    • Randall DC, Fleck NL, Shneerson JM, et al. The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers. Pharmacol Biochem Behav 2004;77:547-555
    • (2004) Pharmacol Biochem Behav , vol.77 , pp. 547-555
    • Randall, D.C.1    Fleck, N.L.2    Shneerson, J.M.3
  • 135
    • 0036679825 scopus 로고    scopus 로고
    • Discriminative-stimulus effects of modafinil in cocaine-trained humans
    • Rush CR, Kelly TH, Hays LR, et al. Discriminative-stimulus effects of modafinil in cocaine-trained humans. Drug Alcohol Depend 2002;67:311-322
    • (2002) Drug Alcohol Depend , vol.67 , pp. 311-322
    • Rush, C.R.1    Kelly, T.H.2    Hays, L.R.3
  • 136
    • 0034061801 scopus 로고    scopus 로고
    • An evaluation of the abuse potential of modafinil using methylphenidate as a reference
    • Jasinski DR. An evaluation of the abuse potential of modafinil using methylphenidate as a reference. J Psychopharmacol 2000;14:53-60
    • (2000) J Psychopharmacol , vol.14 , pp. 53-60
    • Jasinski, D.R.1
  • 137
    • 0343963779 scopus 로고    scopus 로고
    • Evaluation of the abuse liability of modafinil and other drugs for excessive daytime sleepiness associated with narcolepsy
    • Jasinski DR, Kovacevic-Ristanovic R. Evaluation of the abuse liability of modafinil and other drugs for excessive daytime sleepiness associated with narcolepsy. Clin Neuropharmacol 2000;23:149-156
    • (2000) Clin Neuropharmacol , vol.23 , pp. 149-156
    • Jasinski, D.R.1    Kovacevic-Ristanovic, R.2
  • 138
    • 18544363907 scopus 로고    scopus 로고
    • Cephalon. 2003 Annual Report. Available at: http://media.corporate-ir. net/media_files/irol/81/81709/reports/2003ar.pdf. Accessibility verified March 2, 2006
    • 2003 Annual Report
  • 139
    • 0036169262 scopus 로고    scopus 로고
    • Maintaining alertness and performance during sleep deprivation: Modafinil versus caffeine
    • Wesensten NJ, Belenky G, Kautz MA, et al. Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine. Psychopharmacology (Berl) 2002;159:238-247
    • (2002) Psychopharmacology (Berl) , vol.159 , pp. 238-247
    • Wesensten, N.J.1    Belenky, G.2    Kautz, M.A.3
  • 141
    • 85039325243 scopus 로고    scopus 로고
    • Modafinil film-coated tablets significantly improve symptoms of attention deficit/hyperactivity disorder in children and adolescents at school and home and overall clinical condition
    • June 6-9, Boca Raton, Fla
    • Greenhill L. Modafinil film-coated tablets significantly improve symptoms of attention deficit/hyperactivity disorder in children and adolescents at school and home and overall clinical condition. Presented at the 45th annual meeting of the New Clinical Drug Evaluation Unit; June 6-9, 2005; Boca Raton, Fla
    • (2005) 45th Annual Meeting of the New Clinical Drug Evaluation Unit
    • Greenhill, L.1
  • 142
    • 85039341355 scopus 로고    scopus 로고
    • Modafinil pediatric formulation has early and sustained effect in ADHD
    • May 21-26, Atlanta, Ga
    • Biederman J. Modafinil pediatric formulation has early and sustained effect in ADHD. Presented at the 158th annual meeting of the American Psychiatric Association; May 21-26, 2005; Atlanta, Ga
    • (2005) 158th Annual Meeting of the American Psychiatric Association
    • Biederman, J.1
  • 143
    • 85039317921 scopus 로고    scopus 로고
    • Modafinil film-coated tablets demonstrate early efficacy in pediatric attention-deficit/hyperactivity disorder and are not associated with withdrawal or discontinuation syndrome
    • June 6-9, Boca Raton, Fia
    • Swanson J. Modafinil film-coated tablets demonstrate early efficacy in pediatric attention-deficit/hyperactivity disorder and are not associated with withdrawal or discontinuation syndrome. Presented at the 45th annual meeting of the New Clinical Drug Evaluation Unit; June 6-9, 2005; Boca Raton, Fia
    • (2005) 45th Annual Meeting of the New Clinical Drug Evaluation Unit
    • Swanson, J.1
  • 144
    • 85039330110 scopus 로고    scopus 로고
    • Cephalon. Cephalon Files New Drug Application for NUVIGIL™. Available at: http://phx.corporate-ir.net/phoenix.zhtml?c=81709& p=irol-newsArticle&ID=690724&highlight=nuvigil. Accessibility verified March 2, 2006
    • Cephalon Files New Drug Application for NUVIGIL™
  • 145
    • 16544370300 scopus 로고    scopus 로고
    • Pharmacologic management of daytime sleepiness
    • Schwartz JR. Pharmacologic management of daytime sleepiness. J Clin Psychiatry 2004;65(suppl 16):46-49
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 16 , pp. 46-49
    • Schwartz, J.R.1
  • 146
    • 0037401522 scopus 로고    scopus 로고
    • Modafinil and cocaine; a double-blind, placebo-controlled drug interaction study
    • Dackis CA, Lynch KG, Yu E, et al. Modafinil and cocaine; a double-blind, placebo-controlled drug interaction study. Drug Alcohol Depend 2003;70:29-37
    • (2003) Drug Alcohol Depend , vol.70 , pp. 29-37
    • Dackis, C.A.1    Lynch, K.G.2    Yu, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.