Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis

Clinical Chemistry

Volumn 52, Issue 9, 2006, Pages 1815-1817

  Gressner, Axel M ^a   Yagmur, Eray ^a   Lahme, Birgit ^a   Gressner, Olav ^b   Stanzel, Sven ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ALCOHOL LIVER DISEASE; ARTICLE; CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOASSAY; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; SENSITIVITY AND SPECIFICITY; SERUM; STATISTICAL ANALYSIS; THROMBOCYTE COUNT; VIRUS HEPATITIS;

FEMALE; HEPATITIS, ALCOHOLIC; HEPATITIS, CHRONIC; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER CIRRHOSIS; MALE; SERUM;

EID: 33748308746     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.070466     Document Type: Article

References (12)

1. Afdhal NH, Nunes D. Evaluation of liver fibrosis: a concise review. Am J Gastroenterol 2004;99:1160-74.
2. Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatol Res 2003;26:1-9.
3. Gressner AM, Weiskirchen R, Breitkopf K, Dooley S. Roles of TGF-β in hepatic fibrosis. Front Biosci 2002;7:d793-807.
4. Williams EJ, Gaça MDA, Brigstock DR, Arthur MJP, Benyon RC. Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells. J Hepatol 2000;32:754-61.
5. Paradis V, Dargere D, Vidaud M, de Gouville A-C, Huet S, Martinez V, et al. Expression of connective tissue growth factor in experimental rat and human liver fibrosis. Hepatology 1999;30:968-76.
6. Cicha I, Garlichs CD, Daniel WG, Goppelt-Struebe M. Activated human platelets release connective tissue growth factor. Thromb Haemost 2004;91:755-60.
7. Kubota S, Kawata K, Yanagita T, Doi H, Kitoh T, Takigawa M. Abundant retention and release of connective tissue growth factor (CTGF/CCN2) by platelets. J Biochem 2004;136:279-82.
8. Tamatani T, Kobayashi H, Tezuka K, Sakamoto S, Suzuki K, Nakanishi T, et al. Establishment of the enzyme-linked immunosorbent assay for connective tissue growth factor (CTGF) and its detection in the sera of biliary atresia. Biochem Biophys Res Commun 1998;251:748-52.
9. Dziadzio M, Usinger W, Leask A, Abraham D, Black CM, Denton C, et al. N-terminal connective tissue growth factor is a marker of the fibrotic phenotype in scleroderma. J Med 2005;98:485-92.
10. Sato S, Nagaoka T, Hasegawa M, Tamatani T, Nakanishi T, Takigawa M, et al. Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis. J Rheumatol 2000;27:149-54.
11. Riser BL, Cortes P, DeNichilo M, Deshmukh PV, Chahal PS, Mohammed AK, et al. Urinary CCN2 (CTGF) as a possible predictor of diabetic nephropathy: preliminary report. Kidney International 2003;64:451-8.
12. Roestenberg P, van Nieuwenhoven FA, Wieten L, Boer P, Diekman T, Wiersinga WM, et al. Connective tissue growth factor is increased in plasma of type 1 diabetic patients with nephropathy. Diabetic Care 2004;27:1164-70.