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Volumn 153, Issue 9, 2012, Pages 1916-1931

Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis

Author keywords

Experimental autoimmune neuritis; Neuroimmunology; Pain hypersensitivity; Peripheral nerve injury; T cells

Indexed keywords

MONOCLONAL ANTIBODY CD28; MONOCLONAL ANTIBODY CD28SUPA; UNCLASSIFIED DRUG;

EID: 84864597351     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.06.005     Document Type: Article
Times cited : (128)

References (76)
  • 1
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • C. Asseman, S. Mauze, M.W. Leach, R.L. Coffman, and F. Powrie An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation J Exp Med 190 1999 995 1004
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 2
    • 78650309320 scopus 로고    scopus 로고
    • The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines
    • P.J. Austin, and G. Moalem-Taylor The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines J Neuroimmunol 229 2010 26 50
    • (2010) J Neuroimmunol , vol.229 , pp. 26-50
    • Austin, P.J.1    Moalem-Taylor, G.2
  • 5
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • G.J. Bennett, and Y.K. Xie A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man PAIN® 33 1988 87 107
    • (1988) PAIN® , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 6
    • 23744517125 scopus 로고    scopus 로고
    • Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
    • N. Beyersdorf, S. Gaupp, K. Balbach, J. Schmidt, K.V. Toyka, C.H. Lin, T. Hanke, T. Hunig, T. Kerkau, and R. Gold Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis J Exp Med 202 2005 445 455
    • (2005) J Exp Med , vol.202 , pp. 445-455
    • Beyersdorf, N.1    Gaupp, S.2    Balbach, K.3    Schmidt, J.4    Toyka, K.V.5    Lin, C.H.6    Hanke, T.7    Hunig, T.8    Kerkau, T.9    Gold, R.10
  • 7
    • 28744450284 scopus 로고    scopus 로고
    • CD28 superagonists put a break on autoimmunity by preferentially activating CD4+CD25+ regulatory T cells
    • N. Beyersdorf, T. Hanke, T. Kerkau, and T. Hunig CD28 superagonists put a break on autoimmunity by preferentially activating CD4+CD25+ regulatory T cells Autoimmun Rev 5 2006 40 45
    • (2006) Autoimmun Rev , vol.5 , pp. 40-45
    • Beyersdorf, N.1    Hanke, T.2    Kerkau, T.3    Hunig, T.4
  • 9
    • 43549106321 scopus 로고    scopus 로고
    • Prevalence of chronic pain with neuropathic characteristics in the general population
    • D. Bouhassira, M. Lanteri-Minet, N. Attal, B. Laurent, and C. Touboul Prevalence of chronic pain with neuropathic characteristics in the general population Pain 136 2008 380 387
    • (2008) Pain , vol.136 , pp. 380-387
    • Bouhassira, D.1    Lanteri-Minet, M.2    Attal, N.3    Laurent, B.4    Touboul, C.5
  • 11
    • 42249104400 scopus 로고    scopus 로고
    • CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain
    • L. Cao, and J.A. DeLeo CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain Eur J Immunol 38 2008 448 458
    • (2008) Eur J Immunol , vol.38 , pp. 448-458
    • Cao, L.1    Deleo, J.A.2
  • 12
    • 35449006679 scopus 로고    scopus 로고
    • Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
    • X. Cao, S.F. Cai, T.A. Fehniger, J. Song, L.I. Collins, D.R. Piwnica-Worms, and T.J. Ley Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance Immunity 27 2007 635 646
    • (2007) Immunity , vol.27 , pp. 635-646
    • Cao, X.1    Cai, S.F.2    Fehniger, T.A.3    Song, J.4    Collins, L.I.5    Piwnica-Worms, D.R.6    Ley, T.J.7
  • 13
    • 33845915104 scopus 로고    scopus 로고
    • Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice
    • Y. Carrier, J. Yuan, V.K. Kuchroo, and H.L. Weiner Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice J Immunol 178 2007 179 185
    • (2007) J Immunol , vol.178 , pp. 179-185
    • Carrier, Y.1    Yuan, J.2    Kuchroo, V.K.3    Weiner, H.L.4
  • 14
    • 33751513963 scopus 로고    scopus 로고
    • Role of spinal microglia in rat models of peripheral nerve injury and inflammation
    • A.K. Clark, C. Gentry, E.J. Bradbury, S.B. McMahon, and M. Malcangio Role of spinal microglia in rat models of peripheral nerve injury and inflammation Eur J Pain 11 2007 223 230
    • (2007) Eur J Pain , vol.11 , pp. 223-230
    • Clark, A.K.1    Gentry, C.2    Bradbury, E.J.3    McMahon, S.B.4    Malcangio, M.5
  • 15
    • 0032978701 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior
    • R.W. Colburn, A.J. Rickman, and J.A. DeLeo The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior Exp Neurol 157 1999 289 304
    • (1999) Exp Neurol , vol.157 , pp. 289-304
    • Colburn, R.W.1    Rickman, A.J.2    Deleo, J.A.3
  • 18
    • 0032079675 scopus 로고    scopus 로고
    • Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior
    • D.E. Coyle Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior Glia 23 1998 75 83
    • (1998) Glia , vol.23 , pp. 75-83
    • Coyle, D.E.1
  • 20
    • 65349147156 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 impairs neuropathic pain through pleiotropic effects
    • S. Echeverry, X.Q. Shi, A. Haw, H. Liu, Z.W. Zhang, and J. Zhang Transforming growth factor-beta1 impairs neuropathic pain through pleiotropic effects Mol Pain 5 2009 16
    • (2009) Mol Pain , vol.5 , pp. 16
    • Echeverry, S.1    Shi, X.Q.2    Haw, A.3    Liu, H.4    Zhang, Z.W.5    Zhang, J.6
  • 21
    • 38849178118 scopus 로고    scopus 로고
    • Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain
    • S. Echeverry, X.Q. Shi, and J. Zhang Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain PAIN® 135 2008 37 47
    • (2008) PAIN® , vol.135 , pp. 37-47
    • Echeverry, S.1    Shi, X.Q.2    Zhang, J.3
  • 23
    • 0034719671 scopus 로고    scopus 로고
    • Tolerance of rat liver allografts induced by short-term selective immunosuppression combining monoclonal antibodies directed against Cd25 and Cd54 with subtherapeutic cyclosporine1
    • H.-J. Gassel, C. Otto, A.M. Gassel, D. Meyer, U. Steger, W. Timmermann, K. Ulrichs, and A. Thiede Tolerance of rat liver allografts induced by short-term selective immunosuppression combining monoclonal antibodies directed against Cd25 and Cd54 with subtherapeutic cyclosporine1 Transplantation 69 2000 1058 1067
    • (2000) Transplantation , vol.69 , pp. 1058-1067
    • Gassel, H.-J.1    Otto, C.2    Gassel, A.M.3    Meyer, D.4    Steger, U.5    Timmermann, W.6    Ulrichs, K.7    Thiede, A.8
  • 24
    • 0141703239 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
    • E.A. Green, L. Gorelik, C.M. McGregor, E.H. Tran, and R.A. Flavell CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes Proc Natl Acad Sci USA 100 2003 10878 10883
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10878-10883
    • Green, E.A.1    Gorelik, L.2    McGregor, C.M.3    Tran, E.H.4    Flavell, R.A.5
  • 25
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 26
    • 49849094011 scopus 로고    scopus 로고
    • Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other
    • D.A. Horwitz, S.G. Zheng, and J.D. Gray Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other Trends Immunol 29 2008 429 435
    • (2008) Trends Immunol , vol.29 , pp. 429-435
    • Horwitz, D.A.1    Zheng, S.G.2    Gray, J.D.3
  • 27
    • 34249661663 scopus 로고    scopus 로고
    • Immune cell involvement in dorsal root ganglia and spinal cord after chronic constriction or transection of the rat sciatic nerve
    • P. Hu, A.L. Bembrick, K.A. Keay, and E.M. McLachlan Immune cell involvement in dorsal root ganglia and spinal cord after chronic constriction or transection of the rat sciatic nerve Brain Behav Immun 21 2007 599 616
    • (2007) Brain Behav Immun , vol.21 , pp. 599-616
    • Hu, P.1    Bembrick, A.L.2    Keay, K.A.3    McLachlan, E.M.4
  • 28
    • 0037067053 scopus 로고    scopus 로고
    • Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat
    • P. Hu, and E.M. McLachlan Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat Neuroscience 112 2002 23 38
    • (2002) Neuroscience , vol.112 , pp. 23-38
    • Hu, P.1    McLachlan, E.M.2
  • 29
    • 79960727016 scopus 로고    scopus 로고
    • Detailed characterization of neuro-immune responses following neuropathic injury in mice
    • C.F. Kim, and G. Moalem-Taylor Detailed characterization of neuro-immune responses following neuropathic injury in mice Brain Res 1405 2011 95 108
    • (2011) Brain Res , vol.1405 , pp. 95-108
    • Kim, C.F.1    Moalem-Taylor, G.2
  • 30
    • 79952440651 scopus 로고    scopus 로고
    • Interleukin-17 contributes to neuroinflammation and neuropathic pain following peripheral nerve injury in mice
    • C.F. Kim, and G. Moalem-Taylor Interleukin-17 contributes to neuroinflammation and neuropathic pain following peripheral nerve injury in mice J Pain 12 2011 370 383
    • (2011) J Pain , vol.12 , pp. 370-383
    • Kim, C.F.1    Moalem-Taylor, G.2
  • 32
    • 0036838536 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • A.P. Kohm, P.A. Carpentier, H.A. Anger, and S.D. Miller Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis J Immunol 169 2002 4712 4716
    • (2002) J Immunol , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 33
    • 33644841622 scopus 로고    scopus 로고
    • Cutting edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells
    • A.P. Kohm, J.S. McMahon, J.R. Podojil, W.S. Begolka, M. DeGutes, D.J. Kasprowicz, S.F. Ziegler, and S.D. Miller Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells J Immunol 176 2006 3301 3305
    • (2006) J Immunol , vol.176 , pp. 3301-3305
    • Kohm, A.P.1    McMahon, J.S.2    Podojil, J.R.3    Begolka, W.S.4    Degutes, M.5    Kasprowicz, D.J.6    Ziegler, S.F.7    Miller, S.D.8
  • 34
    • 33744752786 scopus 로고    scopus 로고
    • Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis
    • F. Leithauser, T. Meinhardt-Krajina, K. Fink, B. Wotschke, P. Moller, and J. Reimann Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis Am J Pathol 168 2006 1898 1909
    • (2006) Am J Pathol , vol.168 , pp. 1898-1909
    • Leithauser, F.1    Meinhardt-Krajina, T.2    Fink, K.3    Wotschke, B.4    Moller, P.5    Reimann, J.6
  • 36
    • 0037352740 scopus 로고    scopus 로고
    • Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist
    • C.H. Lin, and T. Hunig Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist Eur J Immunol 33 2003 626 638
    • (2003) Eur J Immunol , vol.33 , pp. 626-638
    • Lin, C.H.1    Hunig, T.2
  • 37
    • 78149483354 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice
    • F. Liu, J. Liu, D. Weng, Y. Chen, L. Song, Q. He, and J. Chen CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice PLoS One 5 2010 e15404
    • (2010) PLoS One , vol.5 , pp. 15404
    • Liu, F.1    Liu, J.2    Weng, D.3    Chen, Y.4    Song, L.5    He, Q.6    Chen, J.7
  • 38
    • 0034192795 scopus 로고    scopus 로고
    • Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury
    • T. Liu, N. van Rooijen, and D.J. Tracey Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury PAIN® 86 2000 25 32
    • (2000) PAIN® , vol.86 , pp. 25-32
    • Liu, T.1    Van Rooijen, N.2    Tracey, D.J.3
  • 39
    • 42749090083 scopus 로고    scopus 로고
    • Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barre syndrome
    • L. Luongo, M. Sajic, J. Grist, A.K. Clark, S. Maione, and M. Malcangio Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barre syndrome Neurosci Lett 437 2008 98 102
    • (2008) Neurosci Lett , vol.437 , pp. 98-102
    • Luongo, L.1    Sajic, M.2    Grist, J.3    Clark, A.K.4    Maione, S.5    Malcangio, M.6
  • 40
    • 33749260151 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease
    • D. Mahajan, Y. Wang, X. Qin, G. Zheng, Y.M. Wang, S.I. Alexander, and D.C. Harris CD4+CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease J Am Soc Nephrol 17 2006 2731 2741
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2731-2741
    • Mahajan, D.1    Wang, Y.2    Qin, X.3    Zheng, G.4    Wang, Y.M.5    Alexander, S.I.6    Harris, D.C.7
  • 41
    • 0031775956 scopus 로고    scopus 로고
    • Partial sciatic nerve injury in the mouse as a model of neuropathic pain: Behavioral and neuroanatomical correlates
    • A.B. Malmberg, and A.I. Basbaum Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates PAIN® 76 1998 215 222
    • (1998) PAIN® , vol.76 , pp. 215-222
    • Malmberg, A.B.1    Basbaum, A.I.2
  • 44
    • 33745153343 scopus 로고    scopus 로고
    • Immune and inflammatory mechanisms in neuropathic pain
    • G. Moalem, and D.J. Tracey Immune and inflammatory mechanisms in neuropathic pain Brain Res Rev 51 2006 240 264
    • (2006) Brain Res Rev , vol.51 , pp. 240-264
    • Moalem, G.1    Tracey, D.J.2
  • 45
    • 8444235981 scopus 로고    scopus 로고
    • T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats
    • G. Moalem, K. Xu, and L. Yu T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats Neuroscience 129 2004 767 777
    • (2004) Neuroscience , vol.129 , pp. 767-777
    • Moalem, G.1    Xu, K.2    Yu, L.3
  • 46
    • 34249744464 scopus 로고    scopus 로고
    • Pain hypersensitivity in rats with experimental autoimmune neuritis, an animal model of human inflammatory demyelinating neuropathy
    • G. Moalem-Taylor, H.N. Allbutt, M.D. Iordanova, and D.J. Tracey Pain hypersensitivity in rats with experimental autoimmune neuritis, an animal model of human inflammatory demyelinating neuropathy Brain Behav Immun 21 2007 699 710
    • (2007) Brain Behav Immun , vol.21 , pp. 699-710
    • Moalem-Taylor, G.1    Allbutt, H.N.2    Iordanova, M.D.3    Tracey, D.J.4
  • 47
  • 48
    • 35348876040 scopus 로고    scopus 로고
    • IPEX, FOXP3 and regulatory T-cells: A model for autoimmunity
    • H.D. Ochs, E. Gambineri, and T.R. Torgerson IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity Immunol Res 38 2007 112 121
    • (2007) Immunol Res , vol.38 , pp. 112-121
    • Ochs, H.D.1    Gambineri, E.2    Torgerson, T.R.3
  • 49
    • 37849027594 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease
    • R.A. O'Connor, and S.M. Anderton Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease J Neuroimmunol 193 2008 1 11
    • (2008) J Neuroimmunol , vol.193 , pp. 1-11
    • O'Connor, R.A.1    Anderton, S.M.2
  • 50
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • P. Pandiyan, L. Zheng, S. Ishihara, J. Reed, and M.J. Lenardo CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells Nat Immunol 8 2007 1353 1362
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 53
    • 45849091466 scopus 로고    scopus 로고
    • A comparison of spinal Iba1 and GFAP expression in rodent models of acute and chronic pain
    • A. Romero-Sandoval, N. Chai, N. Nutile-McMenemy, and J.A. Deleo A comparison of spinal Iba1 and GFAP expression in rodent models of acute and chronic pain Brain Res 1219 2008 116 126
    • (2008) Brain Res , vol.1219 , pp. 116-126
    • Romero-Sandoval, A.1    Chai, N.2    Nutile-Mcmenemy, N.3    Deleo, J.A.4
  • 55
    • 0034319204 scopus 로고    scopus 로고
    • Limited role of macrophages in generation of nerve injury-induced mechanical allodynia
    • M.D. Rutkowski, J.L. Pahl, S. Sweitzer, N. van Rooijen, and J.A. DeLeo Limited role of macrophages in generation of nerve injury-induced mechanical allodynia Physiol Behav 71 2000 225 235
    • (2000) Physiol Behav , vol.71 , pp. 225-235
    • Rutkowski, M.D.1    Pahl, J.L.2    Sweitzer, S.3    Van Rooijen, N.4    Deleo, J.A.5
  • 56
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • S. Sakaguchi Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self Nat Immunol 6 2005 345 352
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 59
    • 77749245817 scopus 로고    scopus 로고
    • In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by Fc gamma RIII+ phagocytes
    • Y.Y. Setiady, J.A. Coccia, and P.U. Park In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by Fc gamma RIII+ phagocytes Eur J Immunol 40 2010 780 786
    • (2010) Eur J Immunol , vol.40 , pp. 780-786
    • Setiady, Y.Y.1    Coccia, J.A.2    Park, P.U.3
  • 60
    • 0034665514 scopus 로고    scopus 로고
    • CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations
    • L.A. Stephens, and D. Mason CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations J Immunol 165 2000 3105 3110
    • (2000) J Immunol , vol.165 , pp. 3105-3110
    • Stephens, L.A.1    Mason, D.2
  • 63
    • 0347814979 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    • F.Y. Tanga, V. Raghavendra, and J.A. DeLeo Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain Neurochem Int 45 2004 397 407
    • (2004) Neurochem Int , vol.45 , pp. 397-407
    • Tanga, F.Y.1    Raghavendra, V.2    Deleo, J.A.3
  • 64
    • 68349131604 scopus 로고    scopus 로고
    • The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population
    • C. Toth, J. Lander, and S. Wiebe The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population Pain Med 10 2009 918 929
    • (2009) Pain Med , vol.10 , pp. 918-929
    • Toth, C.1    Lander, J.2    Wiebe, S.3
  • 65
    • 56849107104 scopus 로고    scopus 로고
    • Prevention of diabetes: Effect of mycophenolate mofetil and anti-CD25 on onset of diabetes in the DRBB rat
    • F. Ugrasbul, W.V. Moore, P.Y. Tong, and K.L. Kover Prevention of diabetes: effect of mycophenolate mofetil and anti-CD25 on onset of diabetes in the DRBB rat Pediatr Diabetes 9 2008 596 601
    • (2008) Pediatr Diabetes , vol.9 , pp. 596-601
    • Ugrasbul, F.1    Moore, W.V.2    Tong, P.Y.3    Kover, K.L.4
  • 66
    • 33750306678 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide- induced monocyte survival through a Fas/Fas ligand-dependent mechanism
    • F. Venet, A. Pachot, A.L. Debard, J. Bohe, J. Bienvenu, A. Lepape, W.S. Powell, and G. Monneret Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism J Immunol 177 2006 6540 6547
    • (2006) J Immunol , vol.177 , pp. 6540-6547
    • Venet, F.1    Pachot, A.2    Debard, A.L.3    Bohe, J.4    Bienvenu, J.5    Lepape, A.6    Powell, W.S.7    Monneret, G.8
  • 68
    • 0031884592 scopus 로고    scopus 로고
    • Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression
    • R. Wagner, M. Janjigian, and R.R. Myers Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression PAIN® 74 1998 35 42
    • (1998) PAIN® , vol.74 , pp. 35-42
    • Wagner, R.1    Janjigian, M.2    Myers, R.R.3
  • 69
    • 74049164847 scopus 로고    scopus 로고
    • Regulatory T cells exert checks and balances on self tolerance and autoimmunity
    • K. Wing, and S. Sakaguchi Regulatory T cells exert checks and balances on self tolerance and autoimmunity Nat Immunol 11 2010 7 13
    • (2010) Nat Immunol , vol.11 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2
  • 70
    • 0037358865 scopus 로고    scopus 로고
    • Anti-CD25 monoclonal antibody modulates cytokine expression and prolongs allografts survival in rats cardiac transplantation
    • J. Xia, X. Jiang, Y. Huang, K. Zhang, S. Xiao, and C. Yang Anti-CD25 monoclonal antibody modulates cytokine expression and prolongs allografts survival in rats cardiac transplantation Chin Med J (Engl) 116 2003 432 435
    • (2003) Chin Med J (Engl) , vol.116 , pp. 432-435
    • Xia, J.1    Jiang, X.2    Huang, Y.3    Zhang, K.4    Xiao, S.5    Yang, C.6
  • 72
    • 59749086849 scopus 로고    scopus 로고
    • Distribution of Foxp3(+) T-regulatory cells in experimental autoimmune neuritis rats
    • Z. Zhang, Z.Y. Zhang, U. Fauser, and H.J. Schluesener Distribution of Foxp3(+) T-regulatory cells in experimental autoimmune neuritis rats Exp Neurol 216 2009 75 82
    • (2009) Exp Neurol , vol.216 , pp. 75-82
    • Zhang, Z.1    Zhang, Z.Y.2    Fauser, U.3    Schluesener, H.J.4
  • 73
    • 40849087805 scopus 로고    scopus 로고
    • Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats
    • Z. Zhang, Z.Y. Zhang, U. Fauser, and H.J. Schluesener Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats Neuroscience 152 2008 495 501
    • (2008) Neuroscience , vol.152 , pp. 495-501
    • Zhang, Z.1    Zhang, Z.Y.2    Fauser, U.3    Schluesener, H.J.4
  • 74
    • 70349247894 scopus 로고    scopus 로고
    • Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
    • Z. Zhang, Z.Y. Zhang, and H.J. Schluesener Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects J Immunol 183 2009 3081 3091
    • (2009) J Immunol , vol.183 , pp. 3081-3091
    • Zhang, Z.1    Zhang, Z.Y.2    Schluesener, H.J.3
  • 75
    • 33646567156 scopus 로고    scopus 로고
    • Activated CD4+CD25+ T cells selectively kill B lymphocytes
    • D.M. Zhao, A.M. Thornton, R.J. DiPaolo, and E.M. Shevach Activated CD4+CD25+ T cells selectively kill B lymphocytes Blood 107 2006 3925 3932
    • (2006) Blood , vol.107 , pp. 3925-3932
    • Zhao, D.M.1    Thornton, A.M.2    Dipaolo, R.J.3    Shevach, E.M.4
  • 76
    • 78651380632 scopus 로고    scopus 로고
    • Simultaneous blockade of costimulatory signals CD28-CD80 and CD40-CD154 combined with monoclonal antibody against CD25 induced a stable chimerism and tolerance without graft-versus-host disease in rat
    • Z.X. Zhu, L.Y. Fan, and Q. Wang Simultaneous blockade of costimulatory signals CD28-CD80 and CD40-CD154 combined with monoclonal antibody against CD25 induced a stable chimerism and tolerance without graft-versus-host disease in rat Eur Surg Res 46 2011 109 117
    • (2011) Eur Surg Res , vol.46 , pp. 109-117
    • Zhu, Z.X.1    Fan, L.Y.2    Wang, Q.3


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