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Volumn 5, Issue 4, 2012, Pages 504-514

Ginseng reverses established cardiomyocyte hypertrophy and postmyocardial infarction-induced hypertrophy and heart failure

Author keywords

Calcineurin; Cardiomegaly; Heart failure; NFAT transcription factors; Panax; Remodeling

Indexed keywords

CALCINEURIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; FIBRONECTIN; GINSENG EXTRACT; TRANSCRIPTION FACTOR NFAT3;

EID: 84864594007     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.112.967489     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 77951927068 scopus 로고    scopus 로고
    • Fact sheet No. 317. September 2011. World Health Organization Web site. Accessed November
    • World Health Organization. Cardiovascular diseases (CVDs). Fact sheet No. 317. September 2011. World Health Organization Web site. http://www.who.int/ mediacentre/factsheets/fs317/en/index.html. Accessed November 2011.
    • (2011) Cardiovascular Diseases (CVDs)
  • 3
    • 80051954602 scopus 로고    scopus 로고
    • Medical therapy for chronic heart failure
    • Krum H, Teerlink JR. Medical therapy for chronic heart failure. Lancet. 2011;378:713-721.
    • (2011) Lancet , vol.378 , pp. 713-721
    • Krum, H.1    Teerlink, J.R.2
  • 4
    • 79960788388 scopus 로고    scopus 로고
    • New and emerging drugs and device therapies for chronic heart failure in patients with systolic ventricular dysfunction
    • Rouleau JL. New and emerging drugs and device therapies for chronic heart failure in patients with systolic ventricular dysfunction. Can J Cardiol. 2011;27:296-301.
    • (2011) Can J Cardiol , vol.27 , pp. 296-301
    • Rouleau, J.L.1
  • 7
    • 79959950762 scopus 로고    scopus 로고
    • Novel therapeutic targets for the treatment of heart failure
    • Tamargo J, López-Sendón J. Novel therapeutic targets for the treatment of heart failure. Nat Rev Drug Discov. 2011;10:536-555.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 536-555
    • Tamargo, J.1    López-Sendón, J.2
  • 8
    • 80053953131 scopus 로고    scopus 로고
    • Therapeutic potential of ginseng for the management of cardiovascular disorders
    • Karmazyn M, Moey M, Gan XT. Therapeutic potential of ginseng for the management of cardiovascular disorders. Drugs. 2011;71:1989-2008.
    • (2011) Drugs , vol.71 , pp. 1989-2008
    • Karmazyn, M.1    Moey, M.2    Gan, X.T.3
  • 9
    • 79952256605 scopus 로고    scopus 로고
    • Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation
    • Guo J, Gan XT, Haist JV, Rajapurohitam V, Zeidan A, Faruq NS, Karmazyn M. Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation. Circ Heart Fail. 2011;4:79-88.
    • (2011) Circ Heart Fail , vol.4 , pp. 79-88
    • Guo, J.1    Gan, X.T.2    Haist, J.V.3    Rajapurohitam, V.4    Zeidan, A.5    Faruq, N.S.6    Karmazyn, M.7
  • 11
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: The good, the bad, and the ugly
    • Frey N, Olson EN. Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol. 2003;65:45-79.
    • (2003) Annu Rev Physiol , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 13
    • 81555204274 scopus 로고    scopus 로고
    • Ginseng (Panax quinquefolius) attenuates leptin-induced ventricular cardiac hypertrophy through inhibition of the p115RhoGEF-RhoA/ROCK-dependent MAPK pathway activation
    • Moey M, Rajapurohitam V, Zeidan A, Karmazyn M. Ginseng (Panax quinquefolius) attenuates leptin-induced ventricular cardiac hypertrophy through inhibition of the p115RhoGEF-RhoA/ROCK-dependent MAPK pathway activation. J Pharm Exp Ther. 2011;339:1-11.
    • (2011) J Pharm Exp Ther , vol.339 , pp. 1-11
    • Moey, M.1    Rajapurohitam, V.2    Zeidan, A.3    Karmazyn, M.4
  • 15
    • 79957467492 scopus 로고    scopus 로고
    • The yin and yang actions of North American ginseng root in modulating the immune function of macrophages
    • Azike CG, Charpentier PA, Jirui H, Pei H, Lui EMK. The yin and yang actions of North American ginseng root in modulating the immune function of macrophages. Chin Med. 2011;6:21-32.
    • (2011) Chin Med , vol.6 , pp. 21-32
    • Azike, C.G.1    Charpentier, P.A.2    Jirui, H.3    Pei, H.4    Lui, E.M.K.5
  • 16
    • 0016804272 scopus 로고
    • Ginseng: Its history, dispersion and folk tradition
    • Goldstein B. Ginseng: its history, dispersion and folk tradition. Am J Chin Med. 1975;3:223-334.
    • (1975) Am J Chin Med , vol.3 , pp. 223-334
    • Goldstein, B.1
  • 17
    • 73849150347 scopus 로고    scopus 로고
    • New achievements in ginseng research and its future prospects
    • Chu SF, Zhang JT. New achievements in ginseng research and its future prospects. Chin J Integr Med. 2009;15:403-408.
    • (2009) Chin J Integr Med , vol.15 , pp. 403-408
    • Chu, S.F.1    Zhang, J.T.2
  • 18
    • 0033982650 scopus 로고    scopus 로고
    • Na(+)/H(+) exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium
    • Yoshida H, Karmazyn M. Na(+)/H(+) exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium. Am J Physiol Heart Circ Physiol. 2000;278:H300-H304.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Yoshida, H.1    Karmazyn, M.2
  • 21
    • 1842579393 scopus 로고    scopus 로고
    • Hypertrophy of the heart: A new therapeutic target?
    • Frey N, Katus HA, Olson EN, Hill JA. Hypertrophy of the heart: a new therapeutic target? Circulation. 2004;109:1580-1589.
    • (2004) Circulation , vol.109 , pp. 1580-1589
    • Frey, N.1    Katus, H.A.2    Olson, E.N.3    Hill, J.A.4
  • 22
    • 80955178910 scopus 로고    scopus 로고
    • Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling
    • Leenders JJ, Pinto YM, Creemers EE. Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling. J Mol Cell Cardiol. 2011;51:156-167.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 156-167
    • Leenders, J.J.1    Pinto, Y.M.2    Creemers, E.E.3
  • 23
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • Taigen T, De Windt LJ, Lim HW, Molkentin JD. Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A. 2000;97:1196-1201.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkentin, J.D.4
  • 24
    • 0037065888 scopus 로고    scopus 로고
    • Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy
    • Takeda Y, Yoneda T, Demura M, Usukura M, Mabuchi H. Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy. Circulation. 2002;105:677-679.
    • (2002) Circulation , vol.105 , pp. 677-679
    • Takeda, Y.1    Yoneda, T.2    Demura, M.3    Usukura, M.4    Mabuchi, H.5
  • 25
    • 54449085350 scopus 로고    scopus 로고
    • Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure
    • Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S. Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure. Circ Res. 2008;103: 891-899.
    • (2008) Circ Res , vol.103 , pp. 891-899
    • Nakamura, T.Y.1    Iwata, Y.2    Arai, Y.3    Komamura, K.4    Wakabayashi, S.5
  • 28
    • 70349397280 scopus 로고    scopus 로고
    • Current evaluation of the millennium phytomedicine- ginseng (I): Etymology, pharmacognosy, phytochemistry, market and regulations
    • Jia L, Zhao Y. Current evaluation of the millennium phytomedicine- ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations. Curr Med Chem. 2009;16:2475-2484.
    • (2009) Curr Med Chem , vol.16 , pp. 2475-2484
    • Jia, L.1    Zhao, Y.2
  • 29
    • 79952012614 scopus 로고    scopus 로고
    • Isolation and analysis of ginseng: Advances and challenges
    • Qi LW, Wang CZ, Yuan CS. Isolation and analysis of ginseng: advances and challenges. Nat Prod Rep. 2011;28:467-495.
    • (2011) Nat Prod Rep , vol.28 , pp. 467-495
    • Qi, L.W.1    Wang, C.Z.2    Yuan, C.S.3
  • 30
    • 77952890538 scopus 로고    scopus 로고
    • Biotransformation by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases
    • Park C-S, Yoo M-H, Noh K-H, Oh D-K. Biotransformation by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases. Appl Microbiol Biotechnol. 2010;87: 9-19.
    • (2010) Appl Microbiol Biotechnol , vol.87 , pp. 9-19
    • Park, C.-S.1    Yoo, M.-H.2    Noh, K.-H.3    Oh, D.-K.4
  • 31
    • 77952624932 scopus 로고    scopus 로고
    • Biotransformation of ginsenosdies Rb1, Rg3 and Rh2 in rat gastrointestinal tracts
    • Qian T, Cai Z. Biotransformation of ginsenosdies Rb1, Rg3 and Rh2 in rat gastrointestinal tracts. Chin Med. 2010;5:19-27.
    • (2010) Chin Med , vol.5 , pp. 19-27
    • Qian, T.1    Cai, Z.2
  • 32
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • MERIT-HT Study Group
    • MERIT-HT Study Group. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet. 1999;353:2001-2007.
    • (1999) Lancet , vol.353 , pp. 2001-2007


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.