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Volumn 16, Issue 19, 2009, Pages 2475-2484

Current evaluation of the millennium phytomedicine- Ginseng (I): Etymology, pharmacognosy, phytochemistry, market and regulations

Author keywords

Ginseng; Ginseng market; Ginsenosides; Pharmacognosy; Phytomedicine; Traditional chinese medicine

Indexed keywords

GINSENG EXTRACT; GINSENOSIDE;

EID: 70349397280     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709788682146     Document Type: Review
Times cited : (235)

References (49)
  • 1
    • 38949096884 scopus 로고    scopus 로고
    • Global governmental investment in nanotechnologies
    • Jia, L. Global governmental investment in nanotechnologies. Curr. NanoSci., 2005, 1, 263-266.
    • (2005) Curr. NanoSci , vol.1 , pp. 263-266
    • Jia, L.1
  • 2
    • 36949031034 scopus 로고    scopus 로고
    • The conduct of drug metabolism studies considered good practice (I): Analytical systems and in vivo studies
    • Liu, X.D.; Jia, L. The conduct of drug metabolism studies considered good practice (I): Analytical systems and in vivo studies. Curr. Drug Metab., 2007, 8, 815-821.
    • (2007) Curr. Drug Metab , vol.8 , pp. 815-821
    • Liu, X.D.1    Jia, L.2
  • 3
    • 0242456680 scopus 로고    scopus 로고
    • Harwood Academic Publishers, Newark, New Jersey
    • Court, W.E. Ginseng: The Genus Panax. Harwood Academic Publishers, Newark, New Jersey. 2000.
    • (2000) Ginseng: The Genus Panax
    • Court, W.E.1
  • 4
    • 0035650950 scopus 로고    scopus 로고
    • Brief introduction of Panax ginseng C.A. Meyer
    • Yun, T.K. Brief introduction of Panax ginseng C.A. Meyer. J. Korean Med. Sci., 2001, 16, 53-55.
    • (2001) J. Korean Med. Sci , vol.16 , pp. 53-55
    • Yun, T.K.1
  • 7
    • 0002948481 scopus 로고    scopus 로고
    • Radix Ginseng
    • WHO, Geneva: World Health Organization
    • WHO. "Radix Ginseng", In, WHO Monographs on Selected Medicinal Plants, Geneva: World Health Organization, 1999, pp. 168-182.
    • (1999) WHO Monographs on Selected Medicinal Plants , pp. 168-182
  • 9
    • 17144461621 scopus 로고    scopus 로고
    • Asian ginseng: Potential therapeutic uses
    • Blumenthal, M. Asian ginseng: Potential therapeutic uses. Adv. Nurse Practice, 2001, 9, 26-28.
    • (2001) Adv. Nurse Practice , vol.9 , pp. 26-28
    • Blumenthal, M.1
  • 11
    • 0018132155 scopus 로고
    • Evaluation of commercial ginseng products
    • Liberti, L.E.; Der Mardersian, D.A. Evaluation of commercial ginseng products. J. Pharm. Sci., 1978, 10, 1487-1489.
    • (1978) J. Pharm. Sci , vol.10 , pp. 1487-1489
    • Liberti, L.E.1    Der Mardersian, D.A.2
  • 12
    • 0007998448 scopus 로고
    • Ginseng quality safety and efficacy
    • Philipson, J.D.; Anderson, L.A. Ginseng quality safety and efficacy. Pharm. J., 1984, 232, 161-165.
    • (1984) Pharm. J , vol.232 , pp. 161-165
    • Philipson, J.D.1    Anderson, L.A.2
  • 13
    • 0026504109 scopus 로고
    • Recent advances on ginseng research in China
    • Liu, C.X.; Xiao, P.G. Recent advances on ginseng research in China. J. Ethnopharmacol., 1992, 36, 27-38.
    • (1992) J. Ethnopharmacol , vol.36 , pp. 27-38
    • Liu, C.X.1    Xiao, P.G.2
  • 14
    • 51649107391 scopus 로고    scopus 로고
    • Red ginseng for treating erectile dysfunction: A systematic review
    • Jang, D.J.; Lee, M.S.; Shin, B.C.; Lee, Y.C.; Ernst, E. Red ginseng for treating erectile dysfunction: A systematic review. Br. J. Clin. Pharmacol., 2008, 66, 444-450.
    • (2008) Br. J. Clin. Pharmacol , vol.66 , pp. 444-450
    • Jang, D.J.1    Lee, M.S.2    Shin, B.C.3    Lee, Y.C.4    Ernst, E.5
  • 17
    • 33846068859 scopus 로고    scopus 로고
    • Isolation, structural determination, and evaluation of the biological activity of 20(S)-25-methoxyl-dammarane-3beta,12beta, 20-triol [20(S)-25-OCH3-PPD], a novel natural product from Panax notoginseng
    • Zhao, Y.; Wang, W.; Han, L.; Rayburn, E.R.; Hill, D.L.; Wang, H.; Zhang, R. Isolation, structural determination, and evaluation of the biological activity of 20(S)-25-methoxyl-dammarane-3beta,12beta, 20-triol [20(S)-25-OCH3-PPD], a novel natural product from Panax notoginseng. Med. Chem., 2007, 3, 51-60.
    • (2007) Med. Chem , vol.3 , pp. 51-60
    • Zhao, Y.1    Wang, W.2    Han, L.3    Rayburn, E.R.4    Hill, D.L.5    Wang, H.6    Zhang, R.7
  • 18
    • 16644403662 scopus 로고    scopus 로고
    • Isolation and identification of minor bioactive saponins from the leaves of Panax notoginseng
    • Jiang, B.; Wang, C.; Han, Y.; Hu, X.; Zheng, L.; Zhao, Y. Isolation and identification of minor bioactive saponins from the leaves of Panax notoginseng. Zhong Yao Cai., 2004, 27, 489-91.
    • (2004) Zhong Yao Cai , vol.27 , pp. 489-491
    • Jiang, B.1    Wang, C.2    Han, Y.3    Hu, X.4    Zheng, L.5    Zhao, Y.6
  • 19
    • 0033805268 scopus 로고    scopus 로고
    • Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: A closer look
    • Davydov, M.; Krikorian, A.D. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: A closer look. J. Ethnopharmacol. 2000, 72, 345-393.
    • (2000) J. Ethnopharmacol , vol.72 , pp. 345-393
    • Davydov, M.1    Krikorian, A.D.2
  • 20
    • 70349399131 scopus 로고    scopus 로고
    • Hankins, A. The Chinese Ginseng Industry. The Business of Herbs. Jemez Springs, New Mexico, 1997, 25.
    • Hankins, A. The Chinese Ginseng Industry. The Business of Herbs. Jemez Springs, New Mexico, 1997, Vol. 25.
  • 22
    • 0002105414 scopus 로고    scopus 로고
    • Herb sales down 15% in mainstream market
    • Blumenthal, M. Herb sales down 15% in mainstream market. Herbalgram, 2001, 51, 69.
    • (2001) Herbalgram , vol.51 , pp. 69
    • Blumenthal, M.1
  • 23
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: Multiple constituents and multiple actions
    • Attele, A.S.; Wu, J.A.; Yuan, C.S. Ginseng pharmacology: Multiple constituents and multiple actions. Biochem. Pharmacol., 1999, 58, 1685-1693.
    • (1999) Biochem. Pharmacol , vol.58 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 25
    • 70349400787 scopus 로고    scopus 로고
    • Pan European Federation of TCM Societies
    • Pan European Federation of TCM Societies. The development of Chinese Pharmacopoeia. 2007, http://www.pefots.com.
    • (2007) The development of Chinese Pharmacopoeia
  • 26
    • 0031966674 scopus 로고    scopus 로고
    • Acidic polysaccharide from Panax ginseng, ginsan, induces Th1 cell and macrophage cytokines and generates LAK cells in synergy with rIL-2
    • Kim, K.H.; Lee, Y.S.; Jung, I.S.; Park, S.Y.; Chung, H.Y.; Lee, I.R.; Yun, Y.S. Acidic polysaccharide from Panax ginseng, ginsan, induces Th1 cell and macrophage cytokines and generates LAK cells in synergy with rIL-2. Planta Medica., 1998, 64, 110-5.
    • (1998) Planta Medica , vol.64 , pp. 110-115
    • Kim, K.H.1    Lee, Y.S.2    Jung, I.S.3    Park, S.Y.4    Chung, H.Y.5    Lee, I.R.6    Yun, Y.S.7
  • 27
    • 34948850764 scopus 로고    scopus 로고
    • Chemoprotective and adjuvant effects of immunomodulator ginsan in cyclophosphamide- treated normal and tumor bearing mice. International Journal of Immunopathology
    • Shim, J.Y.; Han, Y.; Ahn, J.Y.; Yun, Y.S.; Song, J.Y. Chemoprotective and adjuvant effects of immunomodulator ginsan in cyclophosphamide- treated normal and tumor bearing mice. International Journal of Immunopathology. Pharmacology, 2007, 20, 487-497.
    • (2007) Pharmacology , vol.20 , pp. 487-497
    • Shim, J.Y.1    Han, Y.2    Ahn, J.Y.3    Yun, Y.S.4    Song, J.Y.5
  • 28
    • 58149166937 scopus 로고    scopus 로고
    • Determination of radix ginseng volatile oils at different ages by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry
    • Qiu, Y.; Lu, X.; Pang, T.; Ma, C.F.; Li, X.; Xu, G.W. Determination of radix ginseng volatile oils at different ages by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. J. Sep. Sci., 2008, 31, 3451-3457.
    • (2008) J. Sep. Sci , vol.31 , pp. 3451-3457
    • Qiu, Y.1    Lu, X.2    Pang, T.3    Ma, C.F.4    Li, X.5    Xu, G.W.6
  • 29
    • 8844246423 scopus 로고    scopus 로고
    • Analysis methods of ginsenosides
    • Fuzzati, N. Analysis methods of ginsenosides. J. Chromatogr. B 2004, 812, 119-133.
    • (2004) J. Chromatogr. B , vol.812 , pp. 119-133
    • Fuzzati, N.1
  • 30
    • 0034508151 scopus 로고    scopus 로고
    • Efficacy and safety of ginseng
    • Kitts, D.D.; Hu, C. Efficacy and safety of ginseng. Pub. Health Nutr., 2000, 3(4A), 473-485.
    • (2000) Pub. Health Nutr , vol.3 , Issue.4 A , pp. 473-485
    • Kitts, D.D.1    Hu, C.2
  • 32
    • 85009578787 scopus 로고
    • A comparative evaluation of ginsenosides in commercial ginseng products and tissue culture samples using HPLC
    • Ma, Y.C.; Zhu, J.; Luo, L. A comparative evaluation of ginsenosides in commercial ginseng products and tissue culture samples using HPLC. J. Herb Spices Med. Plants, 1995, 3, 41-50.
    • (1995) J. Herb Spices Med. Plants , vol.3 , pp. 41-50
    • Ma, Y.C.1    Zhu, J.2    Luo, L.3
  • 33
    • 70349380203 scopus 로고    scopus 로고
    • USP 27 NF 22, United States Pharmacopeial Convention Inc
    • USP 27 NF 22, United States Pharmacopeial Convention Inc., Rockville, MD, 2004, p. 2005.
    • Rockville, MD , vol.2004 , pp. 2005
  • 34
    • 70349399130 scopus 로고    scopus 로고
    • European Pharmacopoeia, 4th ed., Council of Europe, Strasbourg, 2002, p. 1244.
    • European Pharmacopoeia, 4th ed., Council of Europe, Strasbourg, 2002, p. 1244.
  • 35
    • 0036384073 scopus 로고    scopus 로고
    • HPLC determination of ginsenosides content in ginseng dietary supplements using ultraviolet detection
    • Li, W.; Fitzloff, J.F. HPLC determination of ginsenosides content in ginseng dietary supplements using ultraviolet detection. J. Liq. Chromatogr. Related Tech., 2002, 25, 2485-2495.
    • (2002) J. Liq. Chromatogr. Related Tech , vol.25 , pp. 2485-2495
    • Li, W.1    Fitzloff, J.F.2
  • 36
    • 0030606112 scopus 로고    scopus 로고
    • Reversed-phase high-performance liquid chromatography determination of ginsenosides of Panax quinquefolium
    • Court, W.A.; Hendel, J.G.; Elmi, J. Reversed-phase high-performance liquid chromatography determination of ginsenosides of Panax quinquefolium. J. Chromatogr. A, 1996, 755, 11-17
    • (1996) J. Chromatogr. A , vol.755 , pp. 11-17
    • Court, W.A.1    Hendel, J.G.2    Elmi, J.3
  • 37
    • 43249111542 scopus 로고    scopus 로고
    • Development and validation of a reversed-phase HPLC method for quantitative determination of ginsenosides Rb1, Rd, F2, and compound K during the process of biotransformation of ginsenoside Rb1
    • Zhou, W.; Li, J.; Li, X.; Yan, Q.; Zhou, P. Development and validation of a reversed-phase HPLC method for quantitative determination of ginsenosides Rb1, Rd, F2, and compound K during the process of biotransformation of ginsenoside Rb1. J. Sep. Sci., 2008, 31, 921-925.
    • (2008) J. Sep. Sci , vol.31 , pp. 921-925
    • Zhou, W.1    Li, J.2    Li, X.3    Yan, Q.4    Zhou, P.5
  • 38
    • 0035816448 scopus 로고    scopus 로고
    • Liquid chromatographic determination of less polar ginsenosides in processed ginseng
    • Kwon, S.W.; Han, S.B.; Park, H.; Kim, J.M.; Park, M.K.; Park, J.H. Liquid chromatographic determination of less polar ginsenosides in processed ginseng. J. Chromatogr. A, 2001, 921, 335-339.
    • (2001) J. Chromatogr. A , vol.921 , pp. 335-339
    • Kwon, S.W.1    Han, S.B.2    Park, H.3    Kim, J.M.4    Park, M.K.5    Park, J.H.6
  • 39
    • 43249119417 scopus 로고    scopus 로고
    • Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research
    • Xie, G.; Plumb, R.; Su, M.; Xu, Z.; Zhao, A.H.; Qiu, M.F.; Long, X.; Liu, Z.; Jia. W. Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research. J. Sep. Sci., 2008, 31, 1015-1026.
    • (2008) J. Sep. Sci , vol.31 , pp. 1015-1026
    • Xie, G.1    Plumb, R.2    Su, M.3    Xu, Z.4    Zhao, A.H.5    Qiu, M.F.6    Long, X.7    Liu, Z.8    Jia, W.9
  • 40
    • 85009708837 scopus 로고    scopus 로고
    • Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration: Measurement of compound K by enzyme immunoassay
    • Akao,T.; Kanaoka, M.; Kobashi, K. Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration: Measurement of compound K by enzyme immunoassay. Biol. Pharm. Bull., 1998, 21, 245-249.
    • (1998) Biol. Pharm. Bull , vol.21 , pp. 245-249
    • Akao, T.1    Kanaoka, M.2    Kobashi, K.3
  • 41
    • 0031830686 scopus 로고    scopus 로고
    • In vitro antigenotoxic activity of novel ginseng saponin metabolites formed by intestinal bacteria
    • Lee, B.H.; Lee, S. J.; Hui, J. H. In vitro antigenotoxic activity of novel ginseng saponin metabolites formed by intestinal bacteria. Planta Medica, 1998, 64, 500-503.
    • (1998) Planta Medica , vol.64 , pp. 500-503
    • Lee, B.H.1    Lee, S.J.2    Hui, J.H.3
  • 42
    • 31044447082 scopus 로고    scopus 로고
    • Cytotoxicity of compound K (IH-901) and ginsenoside Rh2, main biotransformants of ginseng saponins by bifidobacteria, against some tumor cells
    • Shin, J.E.; Park, E. K. Cytotoxicity of compound K (IH-901) and ginsenoside Rh2, main biotransformants of ginseng saponins by bifidobacteria, against some tumor cells. J. Ginseng Res., 2003, 27, 129-134.
    • (2003) J. Ginseng Res , vol.27 , pp. 129-134
    • Shin, J.E.1    Park, E.K.2
  • 44
    • 13844280922 scopus 로고    scopus 로고
    • Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol type ginsenosides in mouse skin
    • Lee, J.Y.; Shin, J. W.; Chun, K. S. Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol type ginsenosides in mouse skin. Carcinogenesis, 2005, 26, 359-367.
    • (2005) Carcinogenesis , vol.26 , pp. 359-367
    • Lee, J.Y.1    Shin, J.W.2    Chun, K.S.3
  • 45
    • 0034536269 scopus 로고    scopus 로고
    • Constitutive beta-glucosidases hydrolyzing ginsenoside Rb1 and Rb2 from human intestinal bacteria
    • Bea, E.A.; Park, S.Y.; Kim, D.H. Constitutive beta-glucosidases hydrolyzing ginsenoside Rb1 and Rb2 from human intestinal bacteria. Biol. Pharm. Bull., 2000, 23, 1481-1485.
    • (2000) Biol. Pharm. Bull , vol.23 , pp. 1481-1485
    • Bea, E.A.1    Park, S.Y.2    Kim, D.H.3
  • 46
    • 36749053972 scopus 로고    scopus 로고
    • Transformation of bioactive compounds by Fusarium sacchari fungus isolated from the soil-cultivated ginseng
    • Han, Y.; Sun, B.; Hu, X.; Zhang, H.; Jiang, B.; Spranger, M.I.; Zhao, Y. Transformation of bioactive compounds by Fusarium sacchari fungus isolated from the soil-cultivated ginseng. J. Agri. Food Chem., 2007, 55, 9373-9.
    • (2007) J. Agri. Food Chem , vol.55 , pp. 9373-9379
    • Han, Y.1    Sun, B.2    Hu, X.3    Zhang, H.4    Jiang, B.5    Spranger, M.I.6    Zhao, Y.7
  • 47
    • 19444385567 scopus 로고    scopus 로고
    • A dammarane glycoside derived from ginsenoside Rb3
    • He, K.; Liu, Y.; Yang, Y.; Li, P.; Yang, L. A dammarane glycoside derived from ginsenoside Rb3. Chem. Pharm. Bull., 2005, 53, 177-9.
    • (2005) Chem. Pharm. Bull , vol.53 , pp. 177-179
    • He, K.1    Liu, Y.2    Yang, Y.3    Li, P.4    Yang, L.5
  • 48
    • 34848886845 scopus 로고    scopus 로고
    • Determination of 25-OH-PPD in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies
    • Zhang, X.R.; Zhang, D.; Xu, J.H.; Gu, J.K.; Zhao, Y.Q. Determination of 25-OH-PPD in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies. J. Chromatogr. B, 2007, 858, 65-70.
    • (2007) J. Chromatogr. B , vol.858 , pp. 65-70
    • Zhang, X.R.1    Zhang, D.2    Xu, J.H.3    Gu, J.K.4    Zhao, Y.Q.5
  • 49
    • 0036403187 scopus 로고    scopus 로고
    • Structure-function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line
    • Popovich, D.G.; Kitts, D.D. Structure-function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line. Arch. Biochem. Biophys., 2000, 406, 1-8.
    • (2000) Arch. Biochem. Biophys , vol.406 , pp. 1-8
    • Popovich, D.G.1    Kitts, D.D.2


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