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Volumn 2, Issue 2, 2012, Pages 148-155

Theranostic imaging of the kinases and proteases that modulate cell death and survival

Author keywords

Apoptosis; Cell death; Molecular imaging; PI3K; Theranostic

Indexed keywords

CASPASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84864566024     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.4077     Document Type: Review
Times cited : (7)

References (40)
  • 2
    • 18244408264 scopus 로고    scopus 로고
    • Annexin-V imaging for noninvasive detection of cardiac allograft rejection
    • Narula J, Acio ER, Narula N, Samuels LE, Fyfe B, Wood D, et al. Annexin-V imaging for noninvasive detection of cardiac allograft rejection. Nat Med. 2001; 7: 1347-52.
    • (2001) Nat Med , vol.7 , pp. 1347-1352
    • Narula, J.1    Acio, E.R.2    Narula, N.3    Samuels, L.E.4    Fyfe, B.5    Wood, D.6
  • 4
    • 0035173736 scopus 로고    scopus 로고
    • Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent
    • Zhao M, Beauregard DA, Loizou L, Davletov B, Brindle KM. Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med. 2001; 7: 1241-4.
    • (2001) Nat Med , vol.7 , pp. 1241-1244
    • Zhao, M.1    Beauregard, D.A.2    Loizou, L.3    Davletov, B.4    Brindle, K.M.5
  • 5
    • 73449117977 scopus 로고    scopus 로고
    • Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia
    • Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, et al. Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia. Circ Cardiovasc Imaging. 2009; 2: 460-7.
    • (2009) Circ Cardiovasc Imaging , vol.2 , pp. 460-467
    • Sosnovik, D.E.1    Garanger, E.2    Aikawa, E.3    Nahrendorf, M.4    Figuiredo, J.L.5    Dai, G.6
  • 7
    • 82955173656 scopus 로고    scopus 로고
    • Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium
    • Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, et al. Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium. Circ Cardiovasc Imaging. 2011; 4: 729-37.
    • (2011) Circ Cardiovasc Imaging , vol.4 , pp. 729-737
    • Huang, S.1    Chen, H.H.2    Yuan, H.3    Dai, G.4    Schuhle, D.T.5    Mekkaoui, C.6
  • 9
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science. 2002; 296: 1655-7.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 10
    • 79957983577 scopus 로고    scopus 로고
    • Targeting the PI3K/Akt/mTOR pathway-beyond rapalogs
    • Markman B, Dienstmann R, Tabernero J. Targeting the PI3K/Akt/mTOR pathway-beyond rapalogs. Oncotarget. 2010; 1: 530-43.
    • (2010) Oncotarget , vol.1 , pp. 530-543
    • Markman, B.1    Dienstmann, R.2    Tabernero, J.3
  • 11
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell. 2007; 129: 1261-74.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 12
    • 0042750799 scopus 로고    scopus 로고
    • Rosenzweig A. Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival
    • Matsui T, Nagoshi T, Rosenzweig A. Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival. Cell Cycle. 2003; 2: 220-3.
    • (2003) Cell Cycle , vol.2 , pp. 220-223
    • Matsui, T.1    Nagoshi, T.2
  • 14
    • 0030829808 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
    • Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, et al. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest. 1997; 100: 1991-9.
    • (1997) J Clin Invest , vol.100 , pp. 1991-1999
    • Li, Q.1    Li, B.2    Wang, X.3    Leri, A.4    Jana, K.P.5    Liu, Y.6
  • 15
    • 57449113246 scopus 로고    scopus 로고
    • Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation
    • Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, et al. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest. 2008; 118: 4058-66.
    • (2008) J Clin Invest , vol.118 , pp. 4058-4066
    • Cortez-Retamozo, V.1    Swirski, F.K.2    Waterman, P.3    Yuan, H.4    Figueiredo, J.L.5    Newton, A.P.6
  • 16
    • 68049103240 scopus 로고    scopus 로고
    • Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function
    • Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, et al. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009; 60: 2314-24.
    • (2009) Arthritis Rheum , vol.60 , pp. 2314-2324
    • Stangenberg, L.1    Ellson, C.2    Cortez-Retamozo, V.3    Ortiz-Lopez, A.4    Yuan, H.5    Blois, J.6
  • 17
    • 0347539774 scopus 로고    scopus 로고
    • Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice
    • Hayakawa Y, Chandra M, Miao W, Shirani J, Brown JH, Dorn GW, 2nd, et al. Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice. Circulation. 2003; 108: 3036-41.
    • (2003) Circulation , vol.108 , pp. 3036-3041
    • Hayakawa, Y.1    Chandra, M.2    Miao, W.3    Shirani, J.4    Brown, J.H.5    Dorn II, G.W.6
  • 18
    • 0032870898 scopus 로고    scopus 로고
    • Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo
    • Holly TA, Drincic A, Byun Y, Nakamura S, Harris K, Klocke FJ, et al. Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo. J Mol Cell Cardiol. 1999; 31: 1709-15.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 1709-1715
    • Holly, T.A.1    Drincic, A.2    Byun, Y.3    Nakamura, S.4    Harris, K.5    Klocke, F.J.6
  • 19
    • 0032570292 scopus 로고    scopus 로고
    • Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor
    • Yaoita H, Ogawa K, Maehara K, Maruyama Y. Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor. Circulation. 1998; 97: 276-81.
    • (1998) Circulation , vol.97 , pp. 276-281
    • Yaoita, H.1    Ogawa, K.2    Maehara, K.3    Maruyama, Y.4
  • 20
    • 0035902451 scopus 로고    scopus 로고
    • Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
    • Matsui T, Tao J, del Monte F, Lee KH, Li L, Picard M, et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation. 2001; 104: 330-5.
    • (2001) Circulation , vol.104 , pp. 330-335
    • Matsui, T.1    Tao, J.2    del Monte, F.3    Lee, K.H.4    Li, L.5    Picard, M.6
  • 21
    • 23644442091 scopus 로고    scopus 로고
    • PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury
    • Nagoshi T, Matsui T, Aoyama T, Leri A, Anversa P, Li L, et al. PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. J Clin Invest. 2005; 115: 2128-38.
    • (2005) J Clin Invest , vol.115 , pp. 2128-2138
    • Nagoshi, T.1    Matsui, T.2    Aoyama, T.3    Leri, A.4    Anversa, P.5    Li, L.6
  • 22
    • 0029965452 scopus 로고    scopus 로고
    • Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
    • Wymann MP, Bulgarelli-Leva G, Zvelebil MJ, Pirola L, Vanhaesebroeck B, Waterfield MD, et al. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol Cell Biol. 1996; 16: 1722-33.
    • (1996) Mol Cell Biol , vol.16 , pp. 1722-1733
    • Wymann, M.P.1    Bulgarelli-Leva, G.2    Zvelebil, M.J.3    Pirola, L.4    Vanhaesebroeck, B.5    Waterfield, M.D.6
  • 25
    • 67649386846 scopus 로고    scopus 로고
    • The antiproliferative cytostatic effects of a self-activating viridin prodrug
    • Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, et al. The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009; 8: 1666-75.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1666-1675
    • Smith, A.1    Blois, J.2    Yuan, H.3    Aikawa, E.4    Ellson, C.5    Figueiredo, J.L.6
  • 28
    • 61949111970 scopus 로고    scopus 로고
    • Enhancing Akt imaging through targeted reporter expression
    • Zhang L, Bhojani MS, Ross BD, Rehemtulla A. Enhancing Akt imaging through targeted reporter expression. Mol Imaging. 2008; 7: 168-74.
    • (2008) Mol Imaging , vol.7 , pp. 168-174
    • Zhang, L.1    Bhojani, M.S.2    Ross, B.D.3    Rehemtulla, A.4
  • 30
    • 82555173133 scopus 로고    scopus 로고
    • Molecular Imaging of TGFbeta-Induced Smad2/3 Phosphorylation Reveals a Role for Receptor Tyrosine Kinases in Modulating TGFbeta Signaling
    • Nyati S, Schinske K, Ray D, Nyati M, Ross BD, Rehemtulla A. Molecular Imaging of TGFbeta-Induced Smad2/3 Phosphorylation Reveals a Role for Receptor Tyrosine Kinases in Modulating TGFbeta Signaling. Clin Cancer Res. 2011; 17: 7424-39.
    • (2011) Clin Cancer Res , vol.17 , pp. 7424-7439
    • Nyati, S.1    Schinske, K.2    Ray, D.3    Nyati, M.4    Ross, B.D.5    Rehemtulla, A.6
  • 32
    • 79957921255 scopus 로고    scopus 로고
    • Molecular imaging of akt enables early prediction of response to molecular targeted therapy
    • Bhojani MS, Nyati MK, Zhao L, Normolle DP, Ross BD, Lawrence TS, et al. Molecular imaging of akt enables early prediction of response to molecular targeted therapy. Transl Oncol. 2011; 4: 122-5.
    • (2011) Transl Oncol , vol.4 , pp. 122-125
    • Bhojani, M.S.1    Nyati, M.K.2    Zhao, L.3    Normolle, D.P.4    Ross, B.D.5    Lawrence, T.S.6
  • 33
    • 79851482376 scopus 로고    scopus 로고
    • Apoptosis imaging: beyond annexin V
    • Niu G, Chen X. Apoptosis imaging: beyond annexin V. J Nucl Med. 2010; 51: 1659-62.
    • (2010) J Nucl Med , vol.51 , pp. 1659-1662
    • Niu, G.1    Chen, X.2
  • 34
    • 65249177729 scopus 로고    scopus 로고
    • An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging
    • Maxwell D, Chang Q, Zhang X, Barnett EM, Piwnica-Worms D. An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging. Bioconjug Chem. 2009; 20: 702-9.
    • (2009) Bioconjug Chem , vol.20 , pp. 702-709
    • Maxwell, D.1    Chang, Q.2    Zhang, X.3    Barnett, E.M.4    Piwnica-Worms, D.5
  • 35
    • 53249155162 scopus 로고    scopus 로고
    • Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects
    • Ray P, De A, Patel M, Gambhir SS. Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clin Cancer Res. 2008; 14: 5801-9.
    • (2008) Clin Cancer Res , vol.14 , pp. 5801-5809
    • Ray, P.1    De, A.2    Patel, M.3    Gambhir, S.S.4
  • 37
    • 67249095097 scopus 로고    scopus 로고
    • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model
    • Barnett EM, Zhang X, Maxwell D, Chang Q, Piwnica-Worms D. Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model. Proc Natl Acad Sci U S A. 2009; 106: 9391-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9391-9396
    • Barnett, E.M.1    Zhang, X.2    Maxwell, D.3    Chang, Q.4    Piwnica-Worms, D.5
  • 38
    • 67651151217 scopus 로고    scopus 로고
    • Comparison of radiolabeled isatin analogs for imaging apoptosis with positron emission tomography
    • Chen DL, Zhou D, Chu W, Herrbrich PE, Jones LA, Rothfuss JM, et al. Comparison of radiolabeled isatin analogs for imaging apoptosis with positron emission tomography. Nucl Med Biol. 2009; 36: 651-8.
    • (2009) Nucl Med Biol , vol.36 , pp. 651-658
    • Chen, D.L.1    Zhou, D.2    Chu, W.3    Herrbrich, P.E.4    Jones, L.A.5    Rothfuss, J.M.6
  • 39
    • 70349481530 scopus 로고    scopus 로고
    • Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide
    • Nguyen QD, Smith G, Glaser M, Perumal M, Arstad E, Aboagye EO. Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide. Proc Natl Acad Sci U S A. 2009; 106: 16375-80.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16375-16380
    • Nguyen, Q.D.1    Smith, G.2    Glaser, M.3    Perumal, M.4    Arstad, E.5    Aboagye, E.O.6
  • 40
    • 66749129069 scopus 로고    scopus 로고
    • Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis
    • Podichetty AK, Wagner S, Schroer S, Faust A, Schafers M, Schober O, et al. Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. J Med Chem. 2009; 52: 3484-95.
    • (2009) J Med Chem , vol.52 , pp. 3484-3495
    • Podichetty, A.K.1    Wagner, S.2    Schroer, S.3    Faust, A.4    Schafers, M.5    Schober, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.