Molecular imaging of epidermal growth factor receptor kinase activity

Analytical Biochemistry

Volumn 417, Issue 1, 2011, Pages 57-64

  Khan, Amjad P ^a   Contessa, Joseph N ^b   Nyati, Mukesh K ^a   Ross, Brian D ^a   Rehemtulla, Alnawaz ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

EGFR; EPS 15; Molecular imaging; Reporter; Split luciferase

Indexed keywords

AMINO ACIDS; CELL PROLIFERATION; CELL SIGNALING; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; ENZYMES; PHOSPHORYLATION;

EGFR; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; EPS-15; PHARMACOKINETICS AND PHARMACODYNAMICS; PHOSPHORYLATED SUBSTRATES; REPORTER; SPLIT LUCIFERASE;

MOLECULAR IMAGING;

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; ERLOTINIB; LUCIFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; CANCER THERAPY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; XENOGRAFT; ANIMAL; DRUG ANTAGONISM; ENZYME SPECIFICITY; HUMAN; LUMINESCENCE; METABOLISM; METHODOLOGY; NUDE MOUSE; REPORTER GENE; REPRODUCIBILITY; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; CELL LINE, TUMOR; GENES, REPORTER; HUMANS; LUMINESCENT MEASUREMENTS; MICE; MICE, NUDE; MOLECULAR IMAGING; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRODUCIBILITY OF RESULTS; SUBSTRATE SPECIFICITY;

EID: 80655137648     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.05.040     Document Type: Article

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