Anti-inflammatory properties of histone deacetylase inhibitors: A mechanistic study

Journal of Trauma and Acute Care Surgery

Volumn 72, Issue 2, 2012, Pages 347-354

  Chong, Wei ^a,c   Li, Yongqing ^a   Liu, Baoling ^a   Liu, Zhengcai ^a   Zhao, Ting ^a   Wonsey, Diane R ^b   Chen, Changmin ^b   Velmahos, George C ^a   DeMoya, Marc A ^a   King, David R ^a   Kung, Andrew L ^b   Alam, Hasan B ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

HIF 1 ; Hypoxia; Macrophages; PHD2; SAHA

Indexed keywords

ANTIINFLAMMATORY AGENT; DRUG ANALYSIS; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHARMACOLOGY; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; RNA; TUMOR NECROSIS FACTOR ALPHA; VORINOSTAT;

ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL HYPOXIA; COLORIMETRY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG THERAPY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; HEMORRHAGIC SHOCK; MACROPHAGE; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANALYSIS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; COLORIMETRY; DRUG EFFECTS; DRUG THERAPY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; MACROPHAGES; METABOLISM; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHARMACOLOGY; REAL-TIME POLYMERASE CHAIN REACTION; RNA; SHOCK, HEMORRHAGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864544598     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e318243d8b2     Document Type: Article

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