메뉴 건너뛰기




Volumn 15, Issue 8, 2012, Pages 1099-1107

Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels

Author keywords

5 HT; Autoradiography; SERT; transgenic; transporter

Indexed keywords

FENCLONINE; FLUOXETINE; RADIOLIGAND; SEROTONIN; SEROTONIN 4 RECEPTOR; SEROTONIN TRANSPORTER;

EID: 84864540931     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145711001258     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 67349199691 scopus 로고    scopus 로고
    • Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice
    • Basselin M, Fox MA, Chang L, Bell JM, et al. (2009). Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. Neuropsychopharmacology 34, 1695-1709.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1695-1709
    • Basselin, M.1    Fox, M.A.2    Chang, L.3    Bell, J.M.4
  • 2
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ('Ecstasy') in serotonin transporter-deficient mice
    • Bengel D, Murphy DL, Andrews AM, Wichems CH, et al. (1998). Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4- methylenedioxymethamphetamine ('Ecstasy') in serotonin transporter-deficient mice. Molecular Pharmacology 53, 649-655.
    • (1998) Molecular Pharmacology , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4
  • 3
    • 1642397405 scopus 로고    scopus 로고
    • In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice
    • Bortolozzi A, Amargos-Bosch M, Toth M, Artigas F, et al. (2004). In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of Neurochemistry 88, 1373-1379.
    • (2004) Journal of Neurochemistry , vol.88 , pp. 1373-1379
    • Bortolozzi, A.1    Amargos-Bosch, M.2    Toth, M.3    Artigas, F.4
  • 4
    • 1642463529 scopus 로고    scopus 로고
    • Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter
    • Bouali S, Evrard A, Chastanet M, Lesch KP, et al. (2003). Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter. European Journal of Neuroscience 18, 2203-2212.
    • (2003) European Journal of Neuroscience , vol.18 , pp. 2203-2212
    • Bouali, S.1    Evrard, A.2    Chastanet, M.3    Lesch, K.P.4
  • 5
    • 0025268525 scopus 로고
    • Influence of dose and oral route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat
    • Caccia S, Cappi M, Fracasso C, Garattini S (1990). Influence of dose and oral route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat. Psychopharmacology (Berlin) 100, 509-514.
    • (1990) Psychopharmacology (Berlin) , vol.100 , pp. 509-514
    • Caccia, S.1    Cappi, M.2    Fracasso, C.3    Garattini, S.4
  • 6
    • 0029811924 scopus 로고    scopus 로고
    • Opposite changes in striatal neuropeptide y immunoreactivity after partial and complete serotonergic depletion in the rat
    • Compan V, Dusticier N, Nieoullon A, Daszuta A (1996a). Opposite changes in striatal neuropeptide y immunoreactivity after partial and complete serotonergic depletion in the rat. Synapse 24, 87-96.
    • (1996) Synapse , vol.24 , pp. 87-96
    • Compan, V.1    Dusticier, N.2    Nieoullon, A.3    Daszuta, A.4
  • 7
    • 0030461138 scopus 로고    scopus 로고
    • Lesion study of the distribution of serotonin 5-HT4 receptors in rat basal ganglia and hippocampus
    • Compan V, Daszuta A, Salin P, Sebben M, et al. (1996b). Lesion study of the distribution of serotonin 5-HT4 receptors in rat basal ganglia and hippocampus. European Journal Neuroscience 8, 2591-2598.
    • (1996) European Journal Neuroscience , vol.8 , pp. 2591-2598
    • Compan, V.1    Daszuta, A.2    Salin, P.3    Sebben, M.4
  • 8
    • 9144257880 scopus 로고    scopus 로고
    • Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice
    • Compan V, Zhou M, Grailhe R, Gazzara RA, et al. (2004). Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. Journal of Neuroscience 24, 412-419.
    • (2004) Journal of Neuroscience , vol.24 , pp. 412-419
    • Compan, V.1    Zhou, M.2    Grailhe, R.3    Gazzara, R.A.4
  • 9
    • 77749324823 scopus 로고    scopus 로고
    • A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: An in vivo molecular imaging study in humans
    • Erritzoe D, Holst K, Frokjaer VG, Licht CL, et al. (2010). A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humans. Journal of Neuroscience 30, 3391-3397.
    • (2010) Journal of Neuroscience , vol.30 , pp. 3391-3397
    • Erritzoe, D.1    Holst, K.2    Frokjaer, V.G.3    Licht, C.L.4
  • 10
    • 78650031732 scopus 로고    scopus 로고
    • An approach for serotonin depletion in pigs: Effects on serotonin receptor binding
    • Ettrup A, Kornum BR, Weikop P, Knudsen GM (2011). An approach for serotonin depletion in pigs: effects on serotonin receptor binding. Synapse 65, 136-145.
    • (2011) Synapse , vol.65 , pp. 136-145
    • Ettrup, A.1    Kornum, B.R.2    Weikop, P.3    Knudsen, G.M.4
  • 11
    • 0033915750 scopus 로고    scopus 로고
    • Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter
    • Fabre V, Beaufour C, Evrard A, Rioux A, et al. (2000). Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. European Journal of Neuroscience 12, 2299-2310.
    • (2000) European Journal of Neuroscience , vol.12 , pp. 2299-2310
    • Fabre, V.1    Beaufour, C.2    Evrard, A.3    Rioux, A.4
  • 12
    • 77249140558 scopus 로고    scopus 로고
    • Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT)
    • Fox MA, Stein AR, French HT, Murphy DL (2010). Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT). British Journal of Pharmacology 159, 879-887.
    • (2010) British Journal of Pharmacology , vol.159 , pp. 879-887
    • Fox, M.A.1    Stein, A.R.2    French, H.T.3    Murphy, D.L.4
  • 14
    • 0035122950 scopus 로고    scopus 로고
    • Modifications of the serotonergic system in mice lacking serotonin transporters: An in vivo electrophysiological study
    • Gobbi G, Murphy DL, Lesch K, Blier P (2001). Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. Journal of Pharmacology and Experimental Therapeutics 296, 987-995.
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.296 , pp. 987-995
    • Gobbi, G.1    Murphy, D.L.2    Lesch, K.3    Blier, P.4
  • 15
    • 0033525170 scopus 로고    scopus 로고
    • Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
    • Greenberg BD, Tolliver TJ, Huang SJ, Li Q, et al. (1999). Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. American Journal of Medical Genetics 88, 83-87.
    • (1999) American Journal of Medical Genetics , vol.88 , pp. 83-87
    • Greenberg, B.D.1    Tolliver, T.J.2    Huang, S.J.3    Li, Q.4
  • 16
    • 0029895783 scopus 로고    scopus 로고
    • Allelic variation of human serotonin transporter gene expression
    • Heils A, Teufel A, Petri S, Stober G, et al. (1996). Allelic variation of human serotonin transporter gene expression. Journal of Neurochemistry 66, 2621-2624.
    • (1996) Journal of Neurochemistry , vol.66 , pp. 2621-2624
    • Heils, A.1    Teufel, A.2    Petri, S.3    Stober, G.4
  • 17
    • 0031918923 scopus 로고    scopus 로고
    • Pharmacokinetics and antidepressant activity of fluoxetine in transgenic mice with elevated serum alpha-1-acid glycoprotein levels
    • Holladay JW, Dewey MJ, Yoo SD (1998). Pharmacokinetics and antidepressant activity of fluoxetine in transgenic mice with elevated serum alpha-1-acid glycoprotein levels. Drug Metabolism and Disposition 26, 20-24.
    • (1998) Drug Metabolism and Disposition , vol.26 , pp. 20-24
    • Holladay, J.W.1    Dewey, M.J.2    Yoo, S.D.3
  • 18
  • 19
    • 0242391960 scopus 로고    scopus 로고
    • Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression
    • Holmes A, Murphy DL, Crawley JN (2003). Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological Psychiatry 54, 953-959.
    • (2003) Biological Psychiatry , vol.54 , pp. 953-959
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 20
    • 0036897940 scopus 로고    scopus 로고
    • Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
    • Holmes A, Yang RJ, Murphy DL, Crawley JN (2002b). Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology 27, 914-923.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 914-923
    • Holmes, A.1    Yang, R.J.2    Murphy, D.L.3    Crawley, J.N.4
  • 21
    • 33947499053 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine induces a protein kinase a/mitogen-activated protein kinase-mediated and macromolecular synthesis-dependent late phase of long-term potentiation in the amygdala
    • Huang YY, Kandel ER (2007). 5-Hydroxytryptamine induces a protein kinase a/mitogen-activated protein kinase-mediated and macromolecular synthesis-dependent late phase of long-term potentiation in the amygdala. Journal of Neuroscience 27, 3111-3119.
    • (2007) Journal of Neuroscience , vol.27 , pp. 3111-3119
    • Huang, Y.Y.1    Kandel, E.R.2
  • 22
    • 77958522468 scopus 로고    scopus 로고
    • Non-linear relationship between 5-HT transporter gene expression and frequency sensitivity of 5-HT signals
    • Jennings KA, Lesch KP, Sharp T, Cragg SJ (2010). Non-linear relationship between 5-HT transporter gene expression and frequency sensitivity of 5-HT signals. Journal of Neurochemistry 115, 965-973.
    • (2010) Journal of Neurochemistry , vol.115 , pp. 965-973
    • Jennings, K.A.1    Lesch, K.P.2    Sharp, T.3    Cragg, S.J.4
  • 23
    • 33748271285 scopus 로고    scopus 로고
    • Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission
    • Jennings KA, Loder MK, Sheward WJ, Pei Q, et al. (2006). Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission. Journal of Neuroscience 26, 8955-8964.
    • (2006) Journal of Neuroscience , vol.26 , pp. 8955-8964
    • Jennings, K.A.1    Loder, M.K.2    Sheward, W.J.3    Pei, Q.4
  • 24
    • 40849086148 scopus 로고    scopus 로고
    • Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function
    • Jennings KA, Sheward WJ, Harmar AJ, Sharp T (2008). Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function. Neuropharmacology 54, 776-783.
    • (2008) Neuropharmacology , vol.54 , pp. 776-783
    • Jennings, K.A.1    Sheward, W.J.2    Harmar, A.J.3    Sharp, T.4
  • 25
    • 0034883141 scopus 로고    scopus 로고
    • Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse
    • Knobelman DA, Hen R, Lucki I (2001). Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. Journal of Pharmacology and Experimental Therapeutics 298, 1083-1091.
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.298 , pp. 1083-1091
    • Knobelman, D.A.1    Hen, R.2    Lucki, I.3
  • 26
    • 28744453389 scopus 로고    scopus 로고
    • Central serotonin depletion affects rat brain areas differently: A qualitative and quantitative comparison between different treatment schemes
    • Kornum BR, Licht CL, Weikop P, Knudsen GM, et al. (2006). Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes. Neuroscience Letters 392, 129-134.
    • (2006) Neuroscience Letters , vol.392 , pp. 129-134
    • Kornum, B.R.1    Licht, C.L.2    Weikop, P.3    Knudsen, G.M.4
  • 27
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A, Sabol SZ, et al. (1996). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274, 1527-1531.
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4
  • 28
    • 77249146374 scopus 로고    scopus 로고
    • Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice
    • Licht CL, Kirkegaard L, Zueger M, Chourbaji S, et al. (2010). Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice. Neurochemistry International 56, 603-610.
    • (2010) Neurochemistry International , vol.56 , pp. 603-610
    • Licht, C.L.1    Kirkegaard, L.2    Zueger, M.3    Chourbaji, S.4
  • 29
    • 65549162668 scopus 로고    scopus 로고
    • The brain 5-HT4 receptor binding is down-regulated in the flinders sensitive line depression model and in response to paroxetine administration
    • Licht CL, Marcussen AB, Wegener G, Overstreet DH, et al. (2009). The brain 5-HT4 receptor binding is down-regulated in the flinders sensitive line depression model and in response to paroxetine administration. Journal of Neurochemistry 109, 1363-1374.
    • (2009) Journal of Neurochemistry , vol.109 , pp. 1363-1374
    • Licht, C.L.1    Marcussen, A.B.2    Wegener, G.3    Overstreet, D.H.4
  • 30
    • 34548246547 scopus 로고    scopus 로고
    • Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action
    • Lucas G, Rymar VV, Du J, Mnie-Filali O, et al. (2007). Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action. Neuron 55, 712-725.
    • (2007) Neuron , vol.55 , pp. 712-725
    • Lucas, G.1    Rymar, V.V.2    Du, J.3    Mnie-Filali, O.4
  • 32
    • 0035869610 scopus 로고    scopus 로고
    • Functional consequences of 5-HT transporter gene disruption on 5-HT(1a) receptor-mediated regulation of dorsal raphe and hippocampal cell activity
    • Mannoury la Cour C, Boni C, Hanoun N, Lesch KP, et al. (2001). Functional consequences of 5-HT transporter gene disruption on 5-HT(1a) receptor-mediated regulation of dorsal raphe and hippocampal cell activity. Journal of Neuroscience 21, 2178-2185.
    • (2001) Journal of Neuroscience , vol.21 , pp. 2178-2185
    • Mannoury La Cour, C.1    Boni, C.2    Hanoun, N.3    Lesch, K.P.4
  • 33
    • 66649123598 scopus 로고    scopus 로고
    • Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo
    • Marner L, Gillings N, Comley RA, Baare WF, et al. (2009). Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo. Journal of Nuclear Medicine 50, 900-908.
    • (2009) Journal of Nuclear Medicine , vol.50 , pp. 900-908
    • Marner, L.1    Gillings, N.2    Comley, R.A.3    Baare, W.F.4
  • 34
    • 77249125796 scopus 로고    scopus 로고
    • Brain imaging of serotonin 4 receptors in humans with 11CSB207145-PET
    • Marner L, Gillings N, Madsen K, Erritzoe D, et al. (2010). Brain imaging of serotonin 4 receptors in humans with 11CSB207145-PET. Neuroimage 50, 855-861.
    • (2010) Neuroimage , vol.50 , pp. 855-861
    • Marner, L.1    Gillings, N.2    Madsen, K.3    Erritzoe, D.4
  • 35
    • 10344221595 scopus 로고    scopus 로고
    • Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression
    • Mathews TA, Fedele DE, Coppelli FM, Avila AM, et al. (2004). Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. Journal of Neuroscience Methods 140, 169-181.
    • (2004) Journal of Neuroscience Methods , vol.140 , pp. 169-181
    • Mathews, T.A.1    Fedele, D.E.2    Coppelli, F.M.3    Avila, A.M.4
  • 36
    • 0029939169 scopus 로고    scopus 로고
    • Polymorphism in serotonin transporter gene associated with susceptibility to major depression
    • Ogilvie AD, Battersby S, Bubb VJ, Fink G, et al. (1996). Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 347, 731-733.
    • (1996) Lancet , vol.347 , pp. 731-733
    • Ogilvie, A.D.1    Battersby, S.2    Bubb, V.J.3    Fink, G.4
  • 37
    • 0242637392 scopus 로고    scopus 로고
    • Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype
    • Ozaki N, Goldman D, Kaye WH, Plotnicov K, et al. (2003). Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular Psychiatry 8, 933-936.
    • (2003) Molecular Psychiatry , vol.8 , pp. 933-936
    • Ozaki, N.1    Goldman, D.2    Kaye, W.H.3    Plotnicov, K.4
  • 39
    • 21244500509 scopus 로고    scopus 로고
    • 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
    • Qu Y, Villacreses N, Murphy DL, Rapoport SI (2005). 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology (Berlin) 180, 12-20.
    • (2005) Psychopharmacology (Berlin) , vol.180 , pp. 12-20
    • Qu, Y.1    Villacreses, N.2    Murphy, D.L.3    Rapoport, S.I.4
  • 40
    • 34548182366 scopus 로고    scopus 로고
    • Human 5-HT transporter availability predicts amygdala reactivity in vivo
    • Rhodes RA, Murthy NV, Dresner MA, Selvaraj S, et al. (2007). Human 5-HT transporter availability predicts amygdala reactivity in vivo. Journal of Neuroscience 27, 9233-9237.
    • (2007) Journal of Neuroscience , vol.27 , pp. 9233-9237
    • Rhodes, R.A.1    Murthy, N.V.2    Dresner, M.A.3    Selvaraj, S.4
  • 41
    • 47249133718 scopus 로고    scopus 로고
    • Fear conditioning and long-term potentiation in the amygdala: What really is the connection?
    • Sah P, Westbrook RF, Luthi A (2008). Fear conditioning and long-term potentiation in the amygdala: what really is the connection? Annals of the New York Academy of Sciences 1129, 88-95.
    • (2008) Annals of the New York Academy of Sciences , vol.1129 , pp. 88-95
    • Sah, P.1    Westbrook, R.F.2    Luthi, A.3
  • 42
    • 5044225659 scopus 로고    scopus 로고
    • Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters
    • Shen HW, Hagino Y, Kobayashi H, Shinohara-Tanaka K, et al. (2004). Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology 29, 1790-1799.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1790-1799
    • Shen, H.W.1    Hagino, Y.2    Kobayashi, H.3    Shinohara-Tanaka, K.4
  • 43
    • 33845896778 scopus 로고    scopus 로고
    • Long-term potentiation in the amygdala: A cellular mechanism of fear learning and memory
    • Sigurdsson T, Doyere V, Cain CK, LeDoux JE (2007). Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memory. Neuropharmacology 52, 215-227.
    • (2007) Neuropharmacology , vol.52 , pp. 215-227
    • Sigurdsson, T.1    Doyere, V.2    Cain, C.K.3    Ledoux, J.E.4
  • 44
    • 0042349489 scopus 로고    scopus 로고
    • Distribution of 5-HT4 receptors in the postmortem human brain-an autoradiographic study using 125ISB 207710
    • Varnas K, Halldin C, Pike VW, Hall H (2003). Distribution of 5-HT4 receptors in the postmortem human brain-an autoradiographic study using 125ISB 207710. European Neuropsychopharmacology 13, 228-234.
    • (2003) European Neuropsychopharmacology , vol.13 , pp. 228-234
    • Varnas, K.1    Halldin, C.2    Pike, V.W.3    Hall, H.4
  • 45
    • 67650446830 scopus 로고    scopus 로고
    • Long-term treatment with fluoxetine induces desensitization of 5-HT4 receptor-dependent signalling and functionality in rat brain
    • Vidal R, Valdizan EM, Mostany R, Pazos A, et al. (2009). Long-term treatment with fluoxetine induces desensitization of 5-HT4 receptor-dependent signalling and functionality in rat brain. Journal of Neurochemistry 110, 1120-1127.
    • (2009) Journal of Neurochemistry , vol.110 , pp. 1120-1127
    • Vidal, R.1    Valdizan, E.M.2    Mostany, R.3    Pazos, A.4
  • 46
    • 77956318009 scopus 로고    scopus 로고
    • Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats
    • Vidal R, Valdizan EM, Vilaro MT, Pazos A, et al. (2010). Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats. British Journal of Pharmacology 161, 695-706.
    • (2010) British Journal of Pharmacology , vol.161 , pp. 695-706
    • Vidal, R.1    Valdizan, E.M.2    Vilaro, M.T.3    Pazos, A.4
  • 47
    • 13344275880 scopus 로고    scopus 로고
    • Regional distribution and ontogeny of 5-HT4 binding sites in rat brain
    • Waeber C, Sebben M, Bockaert J, Dumuis A (1996). Regional distribution and ontogeny of 5-HT4 binding sites in rat brain. Behavioural Brain Research 73, 259-262.
    • (1996) Behavioural Brain Research , vol.73 , pp. 259-262
    • Waeber, C.1    Sebben, M.2    Bockaert, J.3    Dumuis, A.4
  • 48
    • 60849133024 scopus 로고    scopus 로고
    • Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation
    • Warner-Schmidt JL, Flajolet M, Maller A, Chen EY, et al. (2009). Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation. Journal of Neuroscience 29, 1937-1946.
    • (2009) Journal of Neuroscience , vol.29 , pp. 1937-1946
    • Warner-Schmidt, J.L.1    Flajolet, M.2    Maller, A.3    Chen, E.Y.4
  • 49
    • 33846448741 scopus 로고    scopus 로고
    • Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    • WellmanCL, Izquierdo A, Garrett JE, Martin KP, et al. (2007). Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. Journal of Neuroscience 27, 684-691.
    • (2007) Journal of Neuroscience , vol.27 , pp. 684-691
    • Wellman, C.L.1    Izquierdo, A.2    Garrett, J.E.3    Martin, K.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.