Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 855-866

  Rashid, Mohd ^a   Husain, Asif ^a   Mishra, Ravinesh ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

1,3,4 oxadiazole; Anticancer activity; Benzimidazole; Microwave assisted

Indexed keywords

1 (1H BENZO[D]IMIDAZOL 2 YL) 3 (5 VINYL 1,3,4 OXADIAZOL 2 YL)PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (2 CHLOROBENZYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (2 HYDROXYPHENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (2 MERCAPTOPHENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (2,4 DICHLOROPHENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (4 HYDROXYPHENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (4 METHOXYPHENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (CHLOROMETHYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (MERCAPTOMETHYL) 1,3,4 OXADIAZOL 2 YL)PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (PHENOXYMETHYL) 1,3,4 OXADIAZOL 2 YL)PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (PROP 1 ENYL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (PYRIDIN 2 YL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 (PYRROLIDIN 2 YL) 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 [(4 METHYLPIPERAZIN 1 YL)METHYL] 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 [(DIETHYLAMINO)METHYL] 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 [5 [(DIPHENYLAMINO)METHYL] 1,3,4 OXADIAZOL 2 YL]PROPAN 1 ONE; 1 [[5 [3 (1H BENZO[D]IMIDAZOL 2 YL) 3 OXOPROPYL] 1,3,4 OXADIAZOL 2 YL]METHYL]INDOLINE 2,3 DIONE; 2 [5 [3 (1H BENZO[D]IMIDAZOL 2 YL) 3 OXOPROPYL] 1,3,4 OXADIAZOL 2 YL)ACETONITRILE; 2 [5 [3 (1H BENZO[D]IMIDAZOL 2 YL) 3 OXOPROPYL] 1,3,4 OXADIAZOL 2 YL]ACETIC ACID; 2 [5 [3 (1H BENZO[D]IMIDAZOL 2 YL) 3 OXOPROPYL] 1,3,4 OXADIAZOL 2 YL]PHENYLACETIC ACID; 3 (5 BENZHYDRYL 1,3,4 OXADIAZOL 2 YL) 1 (1H BENZO[D]IMIDAZOL 2 YL)PROPAN 1 ONE; 3 [5 (1 AMINO 3 METHYLBUTYL) 1,3,4 OXADIAZOL 2 YL] 1 (1H BENZO[D]IMIDAZOL 2 YL)PROPAN 1 ONE; 3 [5 (2 AMINOPHENYL) 1,3,4 OXADIAZOL 2 YL] 1 (1H BENZO[D]IMIDAZOL 2 YL)PROPAN 1 ONE; 3 [5 (4 AMINO 2 HYDROXYPHENYL) 1,3,4 OXADIAZOL 2 YL] 1 (1H BENZO[D]IMIDAZOL 2 YL)PROPAN 1 ONE; 4 (1H BENZO[D]IMIDAZOL 2 YL) 4 OXOBUTANE HYDRAZIDE; 4 (1H BENZO[D]IMIDAZOL 2 YL) 4 OXOBUTANOIC ACID; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; ETHYL 4 (1H BENZO[D]IMIDAZOL 2 YL) 4 OXOBUTANOIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROWAVE IRRADIATION;

ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; OXADIAZOLES;

EID: 84864408927     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.04.027     Document Type: Article

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