An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4492-4494

  Kumar, Dalip ^a   Sundaree, Swapna ^a   Johnson, Emmanuel O ^b   Shah, Kavita ^b  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b PURDUE UNIVERSITY   (United States)

Author keywords

1,3,4 Oxadiazole; Anticancer agent; Hypervalent iodine; Selective cytotoxicity; Solvent free

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 5 (3' INDOLYL) 2 (SUBSTITUTED) 1,3,4 OXADIAZOLE DERIVATIVE; 5 (3' INDOLYL) 2 PHENYL 1,3,4 OXADIAZOLE DERIVATIVE; [BIS(TRIFLUOROACETOXY)IODO]BENZENE DERIVATIVE; ACYLHYDRAZONE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZENE DERIVATIVE; HYDRAZONE DERIVATIVE; INDOLYL 1,3,4 OXADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; IODINE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NEOPLASMS; OXADIAZOLES; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67649950035     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.172     Document Type: Article

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