Calcium carbonate microparticles used as a gene vector for delivering p53 gene into cancer cells

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 9, 2012, Pages 2312-2318

  Kong, Xiangdong ^a   Xu, Suju ^a   Wang, Xiumei ^b   Cui, Fuzhai ^b   Yao, Juming ^a  

^a ZHEJIANG SCI TECH UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

calcite; calcium carbonate; gene therapy; transfection; tumor suppressor gene

Indexed keywords

CANCER CELLS; CRYSTAL VIOLET; FLOW-CYTOMETER; FUSION PROTEINS; GENE TRANSFECTION; GENE VECTORS; GREEN FLUORESCENT PROTEIN; HELA CELL; HUMAN CANCER CELLS; MICRO-PARTICLES; MTT ASSAYS; P53 GENE; TRANSFECTION; TUMOR CELLS; TUMOR SUPPRESSOR GENES;

CALCITE; CELL CULTURE; CELL DEATH; GENE THERAPY;

CALCIUM CARBONATE;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCIUM CARBONATE; CRYSTAL VIOLET; GREEN FLUORESCENT PROTEIN; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; FLOW CYTOMETRY; GENE TARGETING; GENE THERAPY; GENE VECTOR; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; STAINING;

APOPTOSIS; CALCIUM CARBONATE; DNA; DRUG CARRIERS; FLUORESCENT DYES; GENE EXPRESSION; GENES, P53; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; NEOPLASMS; PLASMIDS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864402203     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34155     Document Type: Article

References (25)

1. Cotrim AP, Baum BJ,. Gene therapy: Some history, applications, problems, and prospects. Toxicol Pathol 2008; 36: 97-103.
2. Atkinson H, Chalmers R,. Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences. Genetica 2010; 138: 485-498.
3. Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SMF, Ciotti M, Das BR, Del Mistro A, Dybikowska A, et al. TP53 codon 72 polymorphism and cervical cancer: A pooled analysis of individual data from 49 studies. Lancet Oncol 2009; 10: 772-784.
4. May P, May E,. Twenty years of p53 research: Structural and functional aspects of the p53 protein (vol 18, pg 7621, 1999). Oncogene 2000; 19: 1734-1734.
5. Daya S, Berns KI,. Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 2008; 21: 583-593.
6. Strambio-De-Castillia C, Niepel M, Rout MP,. The nuclear pore complex: Bridging nuclear transport and gene regulation. Nat Rev Mol Cell Biol 2010; 11: 490-501.
7. Al-Dosari MS, Gao X,. Nonviral gene delivery: Principle, limitations, and recent progress. Aaps J 2009; 11: 671-681.
8. Donkuru M, Badea I, Wettig S, Verrall R, Elsabahy M, Foldvari M,. Advancing nonviral gene delivery: Lipid- and surfactant-based nanoparticle design strategies. Nanomedicine 2010; 5: 1103-1127.
9. Choi SH, Jin SE, Lee MK, Lim SJ, Park JS, Kim BG, Ahn WS, Kim CK,. Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells. Eur J Pharma Biopharma 2008; 68: 545-554.
10. Motskin M, Wright DM, Muller K, Kyle N, Gard TG, Porter AE, Skepper JN,. Hydroxyapatite nano and microparticles: Correlation of particle properties with cytotoxicity and biostability. Biomaterials 2009; 30: 3307-3317.
11. Chen B, Wu W, Wang X,. Magnetic iron oxide nanoparticles for tumor-targeted therapy. Current Cancer Drug Targets 2011; 11: 184-189.
12. Ladewig K, Xu ZP, Lu GQ,. Layered double hydroxide nanoparticles in gene and drug delivery. Expert Opin Drug Deliv 2009; 6: 907-922.
13. Zhang Q, Zhao D, Zhang XZ, Cheng SX, Zhuo RX,. Calcium phosphate/DNA co-precipitates encapsulated fast-degrading polymer films for substrate-mediated gene delivery. J Biomed Mater Res Part B-Appl Biomater 2009; 91: 172-180.
14. Uskokovic V, Uskokovic DP,. Nanosized hydroxyapatite and other calcium phosphates: Chemistry of formation and application as drug and gene delivery agents. J Biomed Mater Res Part B-Appl Biomater 2011; 96B: 152-191.
15. Cheang TY, Wang SM, Hu ZJ, Xing ZH, Chang GQ, Yao C, Liu Y, Zhang H, Xu AW,. Calcium carbonate/CaIP6 nanocomposite particles as gene delivery vehicles for human vascular smooth muscle cells. J Mater Chem 2010; 20: 8050-8055.
16. Volodkin DV, von Klitzing R, Mohwald H,. Pure protein microspheres by calcium carbonate templating. Angewandte Chemie-Int Ed 2010; 49: 9258-9261.
17. Chen S, Li F, Zhuo RX, Cheng SX,. Efficient non-viral gene delivery mediated by nanostructured calcium carbonate in solution-based transfection and solid-phase transfection. Mol Biosyst 2011; 7: 2841-2847.
18. Martínez-Zaguilán R, Seftor EA, Seftor REB, Chu YW, Gillies RJ, Hendrix MJC,. Acidic pH enhances the invasive behavior of human melanoma cells. Clin Exp Metastasis 1996; 14: 176-186
19. Pan Y, Zhao X, Guo YP, Lv XT, Ren SX, Yuan MR, Wang ZC,. Controlled synthesis of hollow calcite microspheres modulated by polyacrylic acid and sodium dodecyl sulfonate. Mater Lett 2007; 61: 2810-2813.
20. Mori Y, Enomae T, Isogai A,. Application of vaterite-type calcium carbonate prepared by ultrasound for ink jet paper. J Imaging Sci Technol 2010; 54: 020504.
21. Conner SD, Schmid SL,. Regulated portals of entry into the cell. Nature 2003; 422: 37-44.
22. Sokolova V, Epple M,. Inorganic nanoparticles as carriers of nucleic acids into cells. Angewandte Chemie-Int Ed 2008; 47: 1382-1395.
23. Bisht S, Bhakta G, Mitra S, Maitra A,. pDNA loaded calcium phosphate nanoparticles: Highly efficient non-viral vector for gene delivery. Int J Pharma 2005; 288: 157-168.
24. Li J, Chen YC, Tseng YC, Mozumdar S, Huang L,. Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery. J Control Release 2010; 142: 416-421.
25. Oh JM, Choi SJ, Lee GE, Han SH, Choy JH,. Inorganic drug-delivery nanovehicle conjugated with cancer-cell-specific ligand. Adv Funct Mater 2009; 19: 1617-1624.