Hydroxyapatite nano and microparticles: Correlation of particle properties with cytotoxicity and biostability

Biomaterials

Volumn 30, Issue 19, 2009, Pages 3307-3317

  Motskin, M ^a   Wright, D M ^a   Muller, K ^a   Kyle, N ^b   Gard, T G ^b   Porter, A E ^c   Skepper, J N ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Cambridge Biostability Ltd   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cytotoxicity; Hydroxyapatite; Nanoparticles; Slow release; Transfection; Vaccine delivery

Indexed keywords

BIOSTABILITY; CELLULAR UPTAKES; DEAD CELLS; FUNCTION OF TIME; HUMAN MONOCYTES; IN-VITRO; MICROPARTICLES; MTT ASSAYS; PARTICLE LOADS; PARTICLE PROPERTIES; PHYSICO-CHEMICAL PROPERTIES; SLOW RELEASE; STEREOLOGY; SYNTHETIC COLLOIDS; TEM; TRANSFECTION; VACCINE DELIVERY; VACCINE VECTORS;

APATITE; CALCIUM; CELL DEATH; COLLOID CHEMISTRY; DISSOLUTION; GELATION; GELS; HYDROXYAPATITE; HYDROXYLATION; NANOPARTICLES; NUCLEIC ACIDS; SPRAY DRYING; TOXIC MATERIALS; TRANSMISSION ELECTRON MICROSCOPY; VACCINES;

CYTOTOXICITY;

CALCIUM; HYDROXYAPATITE; LACTATE DEHYDROGENASE; NANOCARRIER;

ARTICLE; CALCIUM CELL LEVEL; CELL ASSAY; CELL DEATH; CELL NUCLEUS; CELL TRANSPORT; CELL VIABILITY; COLLOID; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DRUG CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; GEL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; MACROPHAGE; MEMBRANE MICROPARTICLE; MONOCYTE; PARTICLE SIZE; PH; PHAGOCYTE; PHAGOSOME; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SLOW DRUG RELEASE; SPRAY DRYING; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

CELL SURVIVAL; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; CYTOTOXINS; DRUG CARRIERS; DURAPATITE; HUMANS; MACROPHAGES; MATERIALS TESTING; MICROSCOPY, ELECTRON; NANOPARTICLES; PARTICLE SIZE; PHAGOCYTOSIS; SURFACE PROPERTIES;

EID: 67349137101     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.02.044     Document Type: Article

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