Calcium phosphate/DNA co-precipitates encapsulated fast-degrading polymer films for substrate-mediated gene delivery

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 91, Issue 1, 2009, Pages 172-180

  Zhang, Qiao ^a   Zhao, Dong ^a   Zhang, Xian Zheng ^a   Cheng, Si Xue ^a   Zhuo, Ren Xi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Biodegradation; Calcium phosphate; Functional polymers; Gene therapy gene delivery; Substrate mediated delivery

Indexed keywords

CELL TRANSFECTION; CHOLIC ACIDS; CO-PRECIPITATES; DEGRADATION MECHANISM; DEPOSITED FILMS; DL-LACTIDE; FUNCTIONALIZED; GENE DELIVERY; GENE TRANSFECTION; HEK293 CELLS; HELA CELL; IN-VITRO; LOCALIZED GENE DELIVERY; SURFACE EROSION;

BIOCHEMISTRY; BIODEGRADABLE POLYMERS; BIODEGRADATION; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; CELL MEMBRANES; DEGRADATION; FUNCTIONAL POLYMERS; GENE TRANSFER; MICROBIOLOGY; NUCLEIC ACIDS; PHOSPHATES; PLASTIC FILMS; POLYMERS; RING OPENING POLYMERIZATION; SUBSTRATES;

POLYMER FILMS;

CALCIUM PHOSPHATE; CHOLIC ACID; DEOXYRIBOSE; DNA; NUCLEIC ACID; PLASMID DNA; POLYMER;

ANIMAL CELL; ARTICLE; BIODEGRADATION; CELL STRAIN HEK293; CONTROLLED STUDY; DEGRADATION; ENCAPSULATION; FILM; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; POLYMERIZATION; PRECIPITATION; SCANNING ELECTRON MICROSCOPY; SYNTHESIS;

ANIMALS; BIOCOMPATIBLE MATERIALS; CALCIUM PHOSPHATES; CELL LINE; CHOLIC ACID; DNA; GENE TRANSFER TECHNIQUES; HUMANS; MATERIALS TESTING; MICE; MOLECULAR STRUCTURE; POLYESTERS; POLYMERS; SURFACE PROPERTIES; TRANSFECTION;

EID: 70049098077     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31387     Document Type: Article

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