Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance

Diabetes

Volumn 61, Issue 8, 2012, Pages 1959-1968

  Yang, Mengliu ^a   Zhang, Zhihong ^a   Wang, Chong ^a   Li, Ke ^a   Li, Shengbing ^a   Boden, Guenther ^b   Li, Ng ^a   Yang, Gangyi ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MESSENGER RNA; NESFATIN 1; PROTEIN FOS; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN THIRD VENTRICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLUCONEOGENESIS; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; HYPERINSULINEMIA; HYPOTHALAMUS NUCLEUS; IMMUNOREACTIVITY; INSULIN METABOLISM; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADENYLATE KINASE; ANIMALS; CALCIUM-BINDING PROTEINS; DIET, HIGH-FAT; DNA-BINDING PROTEINS; GLUCOSE; INJECTIONS, INTRAVENTRICULAR; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MUSCLE, SKELETAL; NERVE TISSUE PROTEINS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANS-ACTIVATORS;

EID: 84864392523     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1755     Document Type: Article

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