-
1
-
-
33745038222
-
Antibiotic production by actinomycetes: the Janus faces of regulation
-
Cundliffe E, (2006) Antibiotic production by actinomycetes: the Janus faces of regulation. J Ind Microbiol Biotechnol 33: 500-506.
-
(2006)
J Ind Microbiol Biotechnol
, vol.33
, pp. 500-506
-
-
Cundliffe, E.1
-
2
-
-
80855147553
-
Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery
-
Baltz RH, (2011) Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery. J Ind Microbiol Biotechnol 38: 1747-1760.
-
(2011)
J Ind Microbiol Biotechnol
, vol.38
, pp. 1747-1760
-
-
Baltz, R.H.1
-
3
-
-
80052077061
-
The regulation of the secondary metabolism of Streptomyces: new links and experimental advances
-
van Wezel GP, McDowall KJ, (2011) The regulation of the secondary metabolism of Streptomyces: new links and experimental advances. Nat Prod Rep 28: 1311-1333.
-
(2011)
Nat Prod Rep
, vol.28
, pp. 1311-1333
-
-
van Wezel, G.P.1
McDowall, K.J.2
-
4
-
-
0030929313
-
A novel family of proteins that regulates antibiotic production in streptomycetes appears to contain an OmpR-like DNA-binding fold
-
Wietzorrek A, Bibb M, (1997) A novel family of proteins that regulates antibiotic production in streptomycetes appears to contain an OmpR-like DNA-binding fold. Mol Microbiol 25: 1181-1184.
-
(1997)
Mol Microbiol
, vol.25
, pp. 1181-1184
-
-
Wietzorrek, A.1
Bibb, M.2
-
5
-
-
33747043508
-
The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development
-
Rigali S, Nothaft H, Noens EE, Schlicht M, Colson S, et al. (2006) The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development. Mol Microbiol 61: 1237-1251.
-
(2006)
Mol Microbiol
, vol.61
, pp. 1237-1251
-
-
Rigali, S.1
Nothaft, H.2
Noens, E.E.3
Schlicht, M.4
Colson, S.5
-
6
-
-
46449120734
-
Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces
-
Rigali S, Titgemeyer F, Barends S, Mulder S, Thomae AW, et al. (2008) Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces. EMBO Reports 9: 670-675.
-
(2008)
EMBO Reports
, vol.9
, pp. 670-675
-
-
Rigali, S.1
Titgemeyer, F.2
Barends, S.3
Mulder, S.4
Thomae, A.W.5
-
7
-
-
85081771216
-
Contributions of methylenomycin to the genetics of antibiotic production
-
O'Rourke S, Chater KF, (2004) Contributions of methylenomycin to the genetics of antibiotic production. Microbiol Aust 25: 2.
-
(2004)
Microbiol Aust
, vol.25
, pp. 2
-
-
O'Rourke, S.1
Chater, K.F.2
-
8
-
-
33746865723
-
Streptomyces inside-out: a new perspective on the bacteria that provide us with antibiotics
-
Chater KF, (2006) Streptomyces inside-out: a new perspective on the bacteria that provide us with antibiotics. Philos Trans R Soc Lond B Biol Sci 361: 761-768.
-
(2006)
Philos Trans R Soc Lond B Biol Sci
, vol.361
, pp. 761-768
-
-
Chater, K.F.1
-
9
-
-
56249143138
-
2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining
-
Corre C, Song L, O'Rourke S, Chater KF, Challis GL, (2008) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining. Proc Natl Acad Sci U S A 105: 17510-17515.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17510-17515
-
-
Corre, C.1
Song, L.2
O'Rourke, S.3
Chater, K.F.4
Challis, G.L.5
-
10
-
-
58449090159
-
Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor
-
O'Rourke S, Wietzorrek A, Fowler K, Corre C, Challis GL, et al. (2009) Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor. Mol Microbiol 71: 763-778.
-
(2009)
Mol Microbiol
, vol.71
, pp. 763-778
-
-
O'Rourke, S.1
Wietzorrek, A.2
Fowler, K.3
Corre, C.4
Challis, G.L.5
-
11
-
-
43249102444
-
The use of the rare UUA codon to define "expression space" for genes involved in secondary metabolism, development and environmental adaptation in streptomyces
-
Chater KF, Chandra G, (2008) The use of the rare UUA codon to define "expression space" for genes involved in secondary metabolism, development and environmental adaptation in streptomyces. J Microbiol 46: 1-11.
-
(2008)
J Microbiol
, vol.46
, pp. 1-11
-
-
Chater, K.F.1
Chandra, G.2
-
12
-
-
77958041963
-
The JCSG high-throughput structural biology pipeline
-
Elsliger M-A, Deacon AM, Godzik A, Lesley SA, Wooley J, et al. (2010) The JCSG high-throughput structural biology pipeline. Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 1137-1142.
-
(2010)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.66
, pp. 1137-1142
-
-
Elsliger, M.-A.1
Deacon, A.M.2
Godzik, A.3
Lesley, S.A.4
Wooley, J.5
-
13
-
-
0037015054
-
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
-
Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, et al. (2002) Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A 99: 11664-11669.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11664-11669
-
-
Lesley, S.A.1
Kuhn, P.2
Godzik, A.3
Deacon, A.M.4
Mathews, I.5
-
14
-
-
3242886389
-
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes
-
Davis IW, Murray LW, Richardson JS, Richardson DC, (2004) MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes. Nucleic Acids Res 32: W615-619.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Davis, I.W.1
Murray, L.W.2
Richardson, J.S.3
Richardson, D.C.4
-
15
-
-
59549088662
-
ProtorP: a protein-protein interaction analysis server
-
Reynolds C, Damerell D, Jones S, (2009) ProtorP: a protein-protein interaction analysis server. Bioinformatics 25: 413-414.
-
(2009)
Bioinformatics
, vol.25
, pp. 413-414
-
-
Reynolds, C.1
Damerell, D.2
Jones, S.3
-
16
-
-
0028071783
-
Overproduction, isolation, and DNA-binding characteristics of Xre, the repressor protein from the Bacillus subtilis defective prophage PBSX
-
McDonnell GE, McConnell DJ, (1994) Overproduction, isolation, and DNA-binding characteristics of Xre, the repressor protein from the Bacillus subtilis defective prophage PBSX. J Bacteriol 176: 5831-5834.
-
(1994)
J Bacteriol
, vol.176
, pp. 5831-5834
-
-
McDonnell, G.E.1
McConnell, D.J.2
-
17
-
-
13844281073
-
High-resolution crystal structure of the restriction-modification controller protein C.AhdI from Aeromonas hydrophila
-
McGeehan JE, Streeter SD, Papapanagiotou I, Fox GC, Kneale GG, (2005) High-resolution crystal structure of the restriction-modification controller protein C.AhdI from Aeromonas hydrophila. J Mol Biol 346: 689-701.
-
(2005)
J Mol Biol
, vol.346
, pp. 689-701
-
-
McGeehan, J.E.1
Streeter, S.D.2
Papapanagiotou, I.3
Fox, G.C.4
Kneale, G.G.5
-
18
-
-
0028871926
-
Dali: a network tool for protein structure comparison
-
Holm L, Sander C, (1995) Dali: a network tool for protein structure comparison. Trends Biochem Sci 20: 478-480.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 478-480
-
-
Holm, L.1
Sander, C.2
-
19
-
-
64149083240
-
Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes
-
Russo S, Schweitzer JE, Polen T, Bott M, Pohl E, (2009) Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes. J Biol Chem 284: 5208-5216.
-
(2009)
J Biol Chem
, vol.284
, pp. 5208-5216
-
-
Russo, S.1
Schweitzer, J.E.2
Polen, T.3
Bott, M.4
Pohl, E.5
-
20
-
-
26444569914
-
Structure and reactivity of hydroxypropylphosphonic acid epoxidase in fosfomycin biosynthesis by a cation- and flavin-dependent mechanism
-
McLuskey K, Cameron S, Hammerschmidt F, Hunter WN, (2005) Structure and reactivity of hydroxypropylphosphonic acid epoxidase in fosfomycin biosynthesis by a cation- and flavin-dependent mechanism. Proc Natl Acad Sci U S A 102: 14221-14226.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14221-14226
-
-
McLuskey, K.1
Cameron, S.2
Hammerschmidt, F.3
Hunter, W.N.4
-
21
-
-
39749145842
-
P22 c2 repressor-operator complex: mechanisms of direct and indirect readout
-
Watkins D, Hsiao C, Woods KK, Koudelka GB, Williams LD, (2008) P22 c2 repressor-operator complex: mechanisms of direct and indirect readout. Biochemistry 47: 2325-2338.
-
(2008)
Biochemistry
, vol.47
, pp. 2325-2338
-
-
Watkins, D.1
Hsiao, C.2
Woods, K.K.3
Koudelka, G.B.4
Williams, L.D.5
-
22
-
-
0032990441
-
PAS domains: internal sensors of oxygen, redox potential, and light
-
Taylor BL, Zhulin IB, (1999) PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol Mol Biol Rev 63: 479-506.
-
(1999)
Microbiol Mol Biol Rev
, vol.63
, pp. 479-506
-
-
Taylor, B.L.1
Zhulin, I.B.2
-
23
-
-
0034636982
-
Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies
-
Miyatake H, Mukai M, Park SY, Adachi S, Tamura K, et al. (2000) Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies. J Mol Biol 301: 415-431.
-
(2000)
J Mol Biol
, vol.301
, pp. 415-431
-
-
Miyatake, H.1
Mukai, M.2
Park, S.Y.3
Adachi, S.4
Tamura, K.5
-
24
-
-
0032510475
-
Structure at 0.85 Å resolution of an early protein photocycle intermediate
-
Genick UK, Soltis SM, Kuhn P, Canestrelli IL, Getzoff ED, (1998) Structure at 0.85 Å resolution of an early protein photocycle intermediate. Nature 392: 206-209.
-
(1998)
Nature
, vol.392
, pp. 206-209
-
-
Genick, U.K.1
Soltis, S.M.2
Kuhn, P.3
Canestrelli, I.L.4
Getzoff, E.D.5
-
25
-
-
0037166263
-
Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family
-
Zhang RG, Kim Y, Skarina T, Beasley S, Laskowski R, et al. (2002) Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family. J Biol Chem 277: 19183-19190.
-
(2002)
J Biol Chem
, vol.277
, pp. 19183-19190
-
-
Zhang, R.G.1
Kim, Y.2
Skarina, T.3
Beasley, S.4
Laskowski, R.5
-
26
-
-
0037182879
-
Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
-
Zhang RG, Pappas T, Brace JL, Miller PC, Oulmassov T, et al. (2002) Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature 417: 971-974.
-
(2002)
Nature
, vol.417
, pp. 971-974
-
-
Zhang, R.G.1
Pappas, T.2
Brace, J.L.3
Miller, P.C.4
Oulmassov, T.5
-
27
-
-
70349777587
-
Structure and signaling mechanism of Per-ARNT-Sim domains
-
Moglich A, Ayers RA, Moffat K, (2009) Structure and signaling mechanism of Per-ARNT-Sim domains. Structure 17: 1282-1294.
-
(2009)
Structure
, vol.17
, pp. 1282-1294
-
-
Moglich, A.1
Ayers, R.A.2
Moffat, K.3
-
28
-
-
2442624510
-
A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor
-
Kurokawa H, Lee DS, Watanabe M, Sagami I, Mikami B, et al. (2004) A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor. J Biol Chem 279: 20186-20193.
-
(2004)
J Biol Chem
, vol.279
, pp. 20186-20193
-
-
Kurokawa, H.1
Lee, D.S.2
Watanabe, M.3
Sagami, I.4
Mikami, B.5
-
29
-
-
47849125383
-
Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2
-
Nakasako M, Zikihara K, Matsuoka D, Katsura H, Tokutomi S, (2008) Structural basis of the LOV1 dimerization of Arabidopsis phototropins 1 and 2. J Mol Biol 381: 718-733.
-
(2008)
J Mol Biol
, vol.381
, pp. 718-733
-
-
Nakasako, M.1
Zikihara, K.2
Matsuoka, D.3
Katsura, H.4
Tokutomi, S.5
-
30
-
-
77954815505
-
Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042
-
Lopez P, Hornung A, Welzel K, Unsin C, Wohlleben W, et al. (2010) Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042. Gene 461: 5-14.
-
(2010)
Gene
, vol.461
, pp. 5-14
-
-
Lopez, P.1
Hornung, A.2
Welzel, K.3
Unsin, C.4
Wohlleben, W.5
-
31
-
-
77953117821
-
Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22
-
Wang J, Yu Y, Tang K, Liu W, He X, et al. (2010) Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22. Appl Environ Microbiol 76: 2335-2344.
-
(2010)
Appl Environ Microbiol
, vol.76
, pp. 2335-2344
-
-
Wang, J.1
Yu, Y.2
Tang, K.3
Liu, W.4
He, X.5
-
32
-
-
1642338888
-
Novel pathway of salicylate degradation by Streptomyces sp. strain WA46
-
Ishiyama D, Vujaklija D, Davies J, (2004) Novel pathway of salicylate degradation by Streptomyces sp. strain WA46. Appl Environ Microbiol 70: 1297-1306.
-
(2004)
Appl Environ Microbiol
, vol.70
, pp. 1297-1306
-
-
Ishiyama, D.1
Vujaklija, D.2
Davies, J.3
-
33
-
-
77952309568
-
Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities
-
Jornvall H, Hedlund J, Bergman T, Oppermann U, Persson B, (2010) Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities. Biochem Biophys Res Commun 396: 125-130.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 125-130
-
-
Jornvall, H.1
Hedlund, J.2
Bergman, T.3
Oppermann, U.4
Persson, B.5
-
34
-
-
0036778196
-
A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus
-
Horinouchi S, (2002) A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus. Front Biosci 7: d2045-2057.
-
(2002)
Front Biosci
, vol.7
-
-
Horinouchi, S.1
-
35
-
-
69949123857
-
DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus
-
Hara H, Ohnishi Y, Horinouchi S, (2009) DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus. Microbiology 155: 2197-2210.
-
(2009)
Microbiology
, vol.155
, pp. 2197-2210
-
-
Hara, H.1
Ohnishi, Y.2
Horinouchi, S.3
-
37
-
-
0026657433
-
Refined 1.8 Å crystal structure of the lambda repressor-operator complex
-
Beamer LJ, Pabo CO, (1992) Refined 1.8 Å crystal structure of the lambda repressor-operator complex. J Mol Biol 227: 177-196.
-
(1992)
J Mol Biol
, vol.227
, pp. 177-196
-
-
Beamer, L.J.1
Pabo, C.O.2
-
38
-
-
41149148236
-
Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts
-
Klock HE, Koesema EJ, Knuth MW, Lesley SA, (2008) Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts. Proteins 71: 982-994.
-
(2008)
Proteins
, vol.71
, pp. 982-994
-
-
Klock, H.E.1
Koesema, E.J.2
Knuth, M.W.3
Lesley, S.A.4
-
39
-
-
18344375268
-
An approach to rapid protein crystallization using nanodroplets
-
Santarsiero BD, Yegian DT, Lee CC, Spraggon G, Gu J, et al. (2002) An approach to rapid protein crystallization using nanodroplets. J Appl Crystallogr 35: 278-281.
-
(2002)
J Appl Crystallogr
, vol.35
, pp. 278-281
-
-
Santarsiero, B.D.1
Yegian, D.T.2
Lee, C.C.3
Spraggon, G.4
Gu, J.5
-
40
-
-
0036896410
-
An automated system to mount cryo-cooled protein crystals on a synchrotron beamline, using compact samples cassettes and a small-scale robot
-
Cohen AE, Ellis PJ, Miller MD, Deacon AM, Phizackerley RP, (2002) An automated system to mount cryo-cooled protein crystals on a synchrotron beamline, using compact samples cassettes and a small-scale robot. J Appl Crystallogr 35: 720-726.
-
(2002)
J Appl Crystallogr
, vol.35
, pp. 720-726
-
-
Cohen, A.E.1
Ellis, P.J.2
Miller, M.D.3
Deacon, A.M.4
Phizackerley, R.P.5
-
43
-
-
0242460576
-
Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0
-
Bricogne G, Vonrhein C, Flensburg C, Schiltz M, Paciorek W, (2003) Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0. Acta Crystallogr Sect D Biol Crystallogr 59: 2023-2030.
-
(2003)
Acta Crystallogr Sect D Biol Crystallogr
, vol.59
, pp. 2023-2030
-
-
Bricogne, G.1
Vonrhein, C.2
Flensburg, C.3
Schiltz, M.4
Paciorek, W.5
-
44
-
-
33748337934
-
The Buccaneer software for automated model building. 1. Tracing protein chains
-
Cowtan K, (2006) The Buccaneer software for automated model building. 1. Tracing protein chains. Acta Crystallogr Sect D Biol Crystallogr 62: 1002-1011.
-
(2006)
Acta Crystallogr Sect D Biol Crystallogr
, vol.62
, pp. 1002-1011
-
-
Cowtan, K.1
-
46
-
-
77957946297
-
-
ed: Cambridge, United Kingdom: Global Phasing Ltd
-
Bricogne G, Blanc E, Brandl M, Flensburg C, Keller P,et al. (2009) BUSTER. 2.8 ed: Cambridge, United Kingdom: Global Phasing Ltd.
-
(2009)
BUSTER. 2.8
-
-
Bricogne, G.1
Blanc, E.2
Brandl, M.3
Flensburg, C.4
Keller, P.5
-
47
-
-
0035964342
-
Electrostatics of nanosystems: application to microtubules and the ribosome
-
Baker NA, Sept D, Joseph S, Holst MJ, McCammon JA, (2001) Electrostatics of nanosystems: application to microtubules and the ribosome. Proc Natl Acad Sci U S A 98: 10037-10041.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
48
-
-
77955591777
-
Hidden Markov model speed heuristic and iterative HMM search procedure
-
Johnson LS, Eddy SR, Portugaly E, (2010) Hidden Markov model speed heuristic and iterative HMM search procedure. BMC Bioinformatics 11: 431.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 431
-
-
Johnson, L.S.1
Eddy, S.R.2
Portugaly, E.3
-
49
-
-
43349102270
-
Computing multiple sequence/structure alignments with the T-coffee package
-
Notredame C (2010) Computing multiple sequence/structure alignments with the T-coffee package. Curr Protoc Bioinformatics Chapter 3: Unit 3.8.1-25.
-
(2010)
Curr Protoc Bioinformatics Chapter 3: Unit 3.8
, pp. 1-25
-
-
Notredame, C.1
-
50
-
-
10044222704
-
CLANS: a Java application for visualizing protein families based on pairwise similarity
-
Frickey T, Lupas A, (2004) CLANS: a Java application for visualizing protein families based on pairwise similarity. Bioinformatics 20: 3702-3704.
-
(2004)
Bioinformatics
, vol.20
, pp. 3702-3704
-
-
Frickey, T.1
Lupas, A.2
-
51
-
-
0027968068
-
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson JD, Higgins DG, Gibson TJ, (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
52
-
-
2142738304
-
WebLogo: a sequence logo generator
-
Crooks GE, Hon G, Chandonia JM, Brenner SE, (2004) WebLogo: a sequence logo generator. Genome Res 14: 1188-1190.
-
(2004)
Genome Res
, vol.14
, pp. 1188-1190
-
-
Crooks, G.E.1
Hon, G.2
Chandonia, J.M.3
Brenner, S.E.4
|