Disruption of the Ugt1 locus in mice resembles human Crigler-Najjar type I disease

Journal of Biological Chemistry

Volumn 283, Issue 12, 2008, Pages 7901-7911

  Nguyen, Nghia ^a   Bonzo, Jessica A ^a   Chen, Shujuan ^a   Chouinard, Sarah ^d   Kelner, Michael J ^b   Hardiman, Gary ^c   Bélanger, Alain ^d   Tukey, Robert H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; BIOCHEMISTRY; BODY FLUIDS; FATTY ACIDS; GENE EXPRESSION; LIVER; METABOLISM; NUCLEIC ACIDS; PROTEINS; RNA; SKIN;

BILE ACIDS; CELLULAR METABOLISMS; ENDOGENOUS SUBSTANCES; GLUCURONIDATION; HYPERBILIRUBINEMIA; KEY ENZYMES; LIVER MICROSOMES; METABOLIC SYNDROMES; NEURO-TRANSMITTERS; SERUM LEVELS; SKIN COLORS;

ANIMAL CELL CULTURE;

BILIRUBIN; BILIRUBIN GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A1; RNA; BILIRUBIN URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CELL METABOLISM; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; EXON; GENE DISRUPTION; GENE EXPRESSION; GENE LOCUS; GLUCURONIDATION; HUMAN; JAUNDICE; LIVER FUNCTION; LIVER MICROSOME; LOSS OF FUNCTION MUTATION; MOUSE; NEWBORN; NEWBORN MORTALITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SKIN COLOR; WILD TYPE; ANIMAL; BLOOD; DISEASE MODEL; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; QUANTITATIVE TRAIT LOCUS; SKIN PIGMENTATION;

MUS;

ANIMALS; BILIRUBIN; CRIGLER-NAJJAR SYNDROME; DISEASE MODELS, ANIMAL; GLUCURONOSYLTRANSFERASE; HUMANS; LIVER; MICE; MICE, KNOCKOUT; QUANTITATIVE TRAIT LOCI; SKIN PIGMENTATION;

EID: 43149112558     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709244200     Document Type: Article

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