Strong neuroprotection with a novel platinum nanoparticle against ischemic stroke- and tissue plasminogen activator-related brain damages in mice

Neuroscience

Volumn 221, Issue , 2012, Pages 47-55

  Takamiya, M ^a   Miyamoto, Y ^b   Yamashita, T ^a   Deguchi, K ^a   Ohta, Y ^a   Abe, K ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cerebral ischemia; Free radical scavenger; Matrix metalloproteinase 9; Neuroprotection; Platinum nanoparticle; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; COLLAGEN TYPE 4; COLLAGENASE 3; GELATINASE A; GELATINASE B; HYDROETHIDINE; N ACETYLGLUCOSAMINE; OCCLUDIN; PLATINUM NANOPARTICLE; REACTIVE OXYGEN METABOLITE; STROMELYSIN; SUPEROXIDE; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN DAMAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR DYSFUNCTION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; REPERFUSION; SIGNAL TRANSDUCTION; ZYMOGRAPHY;

ANIMALS; BRAIN INFARCTION; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MALE; MATRIX METALLOPROTEINASE 9; METAL NANOPARTICLES; MICE; MICE, INBRED C57BL; MOVEMENT DISORDERS; PHENANTHRIDINES; PLATINUM; REACTIVE OXYGEN SPECIES; REGIONAL BLOOD FLOW; REPERFUSION; SPECTROSCOPY, NEAR-INFRARED; SUPEROXIDES; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84864345113     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.06.060     Document Type: Article

References (59)

1. Abe K. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J Cereb Blood Flow Metab 2000, 20:1393-1408.
2. Abe K., Kawagoe J., Araki T., Aoki M., Kogure K. Differential expression of heat shock protein 70 gene between the cortex and caudate after transient focal cerebral ischaemia in rats. Neurol Res 1992, 14:381-385.
3. Abe K., Yuki S., Kogure K. Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger. Stroke 1988, 19:480-485.
4. Abu Fanne R., Nassar T., Yarovoi S., Rayan A., Lamensdorf I., Karakoveski M., Vadim P., Jammal M., Cines D.B., Higazi A.A. Blood-brain barrier permeability and tPA-mediated neurotoxicity. Neuropharmacology 2010, 58:972-980.
5. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476.
6. Bindokas V.P., Jordán J., Lee C.C., Miller R.J. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 1996, 16:1324-1336.
7. Chan P.H. Role of oxidants in ischemic brain damage. Stroke 1996, 27:1124-1129.
8. Chan P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 2001, 21:2-14.
9. Cui J., Holmes E.H., Greene T.G., Liu P.K. Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain. FASEB J 2000, 14:955-967.
10. Deguchi K., Hayashi T., Nagotani S., Sehara Y., Zhang H., Tsuchiya A., Ohta Y., Tomiyama K., Morimoto N., Miyazaki M., Huh N.H., Nakao A., Kamiya T., Abe K. Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress. Brain Res 2008, 1188:1-8.
11. Demopoulos H.B. The basis of free radical pathology. Fed Proc 1973, 32:1859-1861.
12. Fanne R.A., Nassar T., Yarovoi S., Rayan A., Lamensdorf I., Karakoveski M., Vadim P., Jammal M., Cines D.B., Higazi A.A. Blood-brain barrier permeability and tPA-mediated neurotoxicity. Neuropharmacology 2010, 58:972-980.
13. Gasche Y., Copin J.C., Sugawara T., Fujimura M., Chan P.H. Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. J Cereb Blood Flow Metab 2001, 21:1393-1400.
14. Hamasaki T., Kashiwagi T., Imada T., Nakamichi N., Aramaki S., Toh K., Morisawa S., Shimakoshi H., Hisaeda Y., Shirahata S. Kinetic analysis of superoxide anion radical-scavenging and hydroxyl radical-scavenging activities of platinum nanoparticles. Langmuir 2008, 24:7354-7364.
15. Hayashi T., Hamakawa K., Nagotani S., Jin G., Li F., Deguchi K., Sehara Y., Zhang H., Nagano I., Shoji M., Abe K. HMG CoA reductase inhibitors reduce ischemic brain injury of Wistar rats through decreasing oxidative stress on neurons. Brain Res 2005, 1037:52-58.
16. Hayashi T., Sakurai M., Itoyama Y., Abe K. Oxidative damage and breakage of DNA in rat brain after transient MCA occlusion. Brain Res 1999, 832:159-163.
17. Hsiao G., Lee J.J., Chen Y.C., Lin J.H., Shen M.Y., Lin K.H., Chou D.S., Sheu J.R. Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia- reperfusion: reduced neutrophil activation and anti-oxidant actions. Biochem Pharmacol 2007, 73:682-693.
18. Kajita M., Hikosaka K., Iitsuka M., Kanayama A., Toshima N., Miyamoto Y. Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide. Free Radic Res 2007, 41:615-626.
19. Kamada H., Yu F., Nito C., Chan P.H. Influence of hyperglycemia on oxidative stress and matrix metalloproteinase-9 activation after focal cerebral ischemia/reperfusion in rats. Stroke 2007, 38:1044-1049.
20. Kilic E., Kilic Ü., Bähr M., Hermann D.M. Tissue plasminogen activator-induced ischemic injuly is reversed by NMDA antagonist MK-801 in vivo. Neurodegenerative Dis 2005, 2:49-55.
21. Kilic E., Kilic U., Matter C.M., Lüscher T.F., Bassetti C.L., Hermann D.M. Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase. Stroke 2005, 36:332-336.
22. Kim J., Shirasawa T., Miyamoto Y. The effect of TAT conjugated platinum nanoparticles on lifespan in a nematode Caenorhabditis elegans model. Biomaterials 2010, 31:5849-5854.
23. Kim J., Takahashi M., Shimizu T., Shirasawa T., Kajita M., Kanayama A., Miyamoto Y. Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans. Mech Ageing Dev 2008, 129:322-331.
24. Kinouchi H., Epstein C.J., Mizui T., Carlson E., Chen S.F., Chan P.H. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc Natl Acad Sci U S A 1991, 88:11158-11162.
25. Kitano H., Nishimura H., Tachibana H., Yoshikawa H., Matsuyama T. ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brain. Brain Res 2004, 1015:122-128.
26. Klohs J., Steinbrink J., Bourayou R., Mueller S., Cordell R., Licha K., Schirner M., Dirnagl U., Lindauer U., Wunder A. Near-infrared fluorescence imaging with fluorescently labeled albumin: a novel method for non-invasive optical imaging of blood-brain barrier impairment after focal cerebral ischemia in mice. J Neurosci Methods 2009, 180:126-132.
27. Kontos C.D., Wei E.P., Williams J.I., Kontos H.A., Povlishock J.T. Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo. Am J Physiol 1992, 263:1234-1242.
28. Kontos H.A. Oxygen radicals in cerebral ischemia. Stroke 2001, 32:2712-2716.
29. Lansberg M.G., Bluhmki E., Thijs V.N. Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis. Stroke 2009, 40:2438-2441.
30. Lukic-Panin V., Deguchi K., Yamashita T., Shang J., Zhang X., Tian F., Liu N., Kawai H., Matsuura T., Abe K. Free radical scavenger edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage. Curr Neurovasc Res 2010, 7:319-329.
31. Lukic-Panin V., Kamiya T., Zhang H., Hayashi T., Tsuchiya A., Sehara Y., Deguchi K., Yamashita T., Abe K. Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats. Brain Res 2007, 1176:143-150.
32. Machado L.S., Sazonova I.Y., Kozak A., Wiley D.C., El-Remessy A.B., Ergul A., Hess D.C., Waller J.L., Fagan S.C. Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential. Stroke 2009, 40:3028-3033.
33. Morimoto T., Globus M.Y., Busto R., Martinez E., Ginsberg M.D. Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 1996, 16:92-99.
34. Nagai N., De Mol M., Lijnen H.R., Carmeliet P., Collen D. Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice. Circulation 1999, 99:2440-2444.
35. Nagotani S., Hayashi T., Sato K., Zhang W., Deguchi K., Nagano I., Shoji M., Abe K. Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress. Stroke 2005, 36:670-672.
36. Ning M., Furie K.L., Koroshetz W.J., Lee H., Barron M., Lederer M., Wang X., Zhu M., Sorensen A.G., Lo E.H., Kelly P.J. Association between tPA therapy and raised early matrix metalloproteinase-9 in acute stroke. Neurology 2006, 66:1550-1555.
37. Onizawa S., Aoshiba K., Kajita M., Miyamoto Y., Nagai A. Platinum nanoparticle antioxidants inhibit pulmonary inflammation in mice exposed to cigarette smoke. Pulm Pharmacol Ther 2009, 22:340-349.
38. Perfeito R., Pereira J., Oliveira C.R., Bettencourt-Relvas J., Rego A.C. Trolox protection of myelin membrane in hydrogen peroxide-treated mature oligodendrocytes. Free Radic Res 2007, 41:444-451.
39. Peters O., Back T., Lindauer U., Busch C., Megow D., Dreier J., Dirnagl U. Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1998, 18:196-205.
40. Roucoux A., Schulz J., Patin H. Reduced transition metal colloids: a novel family of reusable catalysts?. Chem Rev 2002, 102:3757-3778.
41. Saitoh Y., Yoshimura Y., Nakano K., Miwa N. Platinum nanocolloid-supplemented hydrogen-dissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells. Exp Oncol 2009, 31:156-162.
42. Sakaue Y., Kim J., Miyamoto Y. Effects of TAT-conjugated platinum nanoparticles on lifespan of mitochondrial electron transport complex I-deficient Caenorhabditis elegans, nuo-1. Int J Nanomedicine 2010, 5:687-695.
43. Sharma S.S., Kaundal R.K. Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Neurol Res 2007, 29:304-309.
44. Sugawara T., Noshita N., Lewén A., Gasche Y., Ferrand-Drake M., Fujimura M., Morita-Fujimura Y., Chan P.H. Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. J Neurosci 2002, 22:209-217.
45. Takamiya M., Miyamoto Y., Yamashita T., Deguchi K., Ohta Y., Ikeda Y., Matsuura T., Abe K. Neurological and pathological improvements of cerebral infarction in mice with platinum nanoparticles. J Neurosci Res 2011, 89:1125-1133.
46. The Edaravone Acute Brain Infarction Study Group Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc Dis 2003, 15:222-229.
47. Tsirka S.E., Gualandris A., Amaral D.G., Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 1995, 377:340-344.
48. Tsuji K., Aoki T., Tejima E., Arai K., Lee S.R., Atochin D.N., Huang P.L., Wang X., Montaner J., Lo E.H. Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia. Stroke 2005, 36:1954-1959.
49. Wahlgren N., Ahmed N., Davalos A., Hacke W., Milian M., Muir K., Roine R.O., Toni D., Lees K.R., SITS investigators Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 2008, 372:1303-1309.
50. Wang X., Lee S.R., Arai K., Tsuji K., Rebeck G.W., Lo E.H. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med 2003, 9:1313-1317.
51. Wang Y.F., Tsirka S.E., Strickland S., Stieg P.E., Soriano S.G., Lipton S.A. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat Med 1998, 4:228-231.
52. Watanabe A., Kajita M., Kim J., Kanayama A., Takahashi K., Mashino T., Miyamoto Y. In vitro free radical scavenging activity of platinum nanoparticles. Nanotechnology 2009, 20:455105.
53. Yagi K., Kitazato K.T., Uno M., Tada Y., Kinouchi T., Shimada K., Nagahiro S. Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Stroke 2009, 40:626-631.
54. Yamashita T., Deguchi K., Sawamoto K., Okano H., Kamiya T., Abe K. Neuroprotection and neurosupplementation in ischaemic brain. Biochem Soc Trans 2006, 34:1310-1312.
55. Yamashita T., Kamiya T., Deguchi K., Inaba T., Zhang H., Shang J., Miyazaki K., Ohtsuka A., Katayama Y., Abe K. Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain. J Cereb Blood Flow Metab 2009, 29:715-725.
56. Yoneda Y., Uehara T., Yamasaki H., Kita Y., Tabuchi M., Mori E. Hospital-based study of the care and cost of acute ischemic stroke in Japan. Stroke 2003, 34:718-724.
57. Yong V.W., Power C., Forsyth P., Edwards D.R. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2001, 2:502-511.
58. Zhang W.R., Hayashi T., Sasaki C., Sato K., Nagano I., Manabe Y., Abe K. Attenuation of oxidative DNA damage with a novel antioxidant EPC-K1 in rat brain neuronal cells after transient middle cerebral artery occlusion. Neurol Res 2001, 23:676-680.
59. Zhang W.R., Sato K., Hayashi T., Omori N., Nagano I., Kato S., Horiuchi S., Abe K. Extension of ischemic therapeutic time window by a free radical scavenger, edaravone, reperfused with tPA in rat brain. Neurol Res 2004, 26:342-348.