Effects of TAT-conjugated platinum nanoparticles on lifespan of mitochondrial electron transport complex I-deficient Caenorhabditis elegans, nuo-I

International Journal of Nanomedicine

Volumn 5, Issue 1, 2010, Pages 687-695

  Sakaue, Yuri ^a   Kim, Juewon ^a   Miyamoto, Yusei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Caenorhabditis elegans; Complex I deficient mutant; LB25; Lifespan; Platinum nanoparticles

Indexed keywords

HYBRID PROTEIN; NANOPARTICLE; PLATINUM DERIVATIVE; POLYPEPTIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRANSACTIVATOR PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; METAL NANOPARTICLE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NUO 1 PROTEIN, C ELEGANS; NUO-1 PROTEIN, C ELEGANS; PEPTIDE FRAGMENT; PLATINUM; TAT PEPTIDE (48 60), HUMAN IMMUNODEFICIENCY VIRUS 1; TAT PEPTIDE (48-60), HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; BINDING AFFINITY; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG CONJUGATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; IN VIVO STUDY; LIFE EXTENSION; LIFESPAN; MITOCHONDRIAL MEMBRANE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; TARGET CELL; WILD TYPE; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; DRUG EFFECT; GENE; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LONGEVITY; METABOLISM; MITOCHONDRION; NANOMEDICINE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; TRANSGENIC ANIMAL;

CAENORHABDITIS ELEGANS; HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SUBSTITUTION; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ELECTRON TRANSPORT COMPLEX I; GENES, HELMINTH; HIV-1; HUMANS; LONGEVITY; METAL NANOPARTICLES; MITOCHONDRIA; MUTAGENESIS, SITE-DIRECTED; NAD; NANOMEDICINE; PEPTIDE FRAGMENTS; PLATINUM; REACTIVE OXYGEN SPECIES; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 79952115266     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S12439     Document Type: Article

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