Neuroprotective effects of PMC, a potent α-tocopherol derivative, in brain ischemia-reperfusion: Reduced neutrophil activation and anti-oxidant actions

Biochemical Pharmacology

Volumn 73, Issue 5, 2007, Pages 682-693

  Hsiao, George ^a   Lee, Jie Jen ^b   Chen, Yi Cheng ^a   Lin, Jiing Harn ^a   Shen, Ming Yi ^a   Lin, Kuang Hung ^a   Chou, Duen Suey ^a   Sheu, Joen Rong ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Caspase 3; Free radical scavenger; HIF 1 ; iNOS; MCAO; PMC

Indexed keywords

3 NITROTYROSINE; 6 HYDROXY 2,2,5,7,8 PENTAMETHYLCHROMAN; ALPHA TOCOPHEROL DERIVATIVE; CASPASE 3; FORMYLMETHIONYLLEUCYLPHENYLALANINE; FREE RADICAL; HYDROXYL RADICAL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; LEUKOTRIENE B4; PHORBOL 13 ACETATE 12 MYRISTATE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; CELL MIGRATION; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HUMAN; INFLAMMATION; LEUKOCYTE ACTIVATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; RESPIRATORY BURST; RISK ASSESSMENT;

ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; CASPASE 3; CHROMANS; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-ISCHEMIA, BRAIN; MALE; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; NEUTROPHIL ACTIVATION; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR; REPERFUSION INJURY; TYROSINE;

EID: 33846529431     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.11.009     Document Type: Article

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