-
1
-
-
33645116252
-
Genetics of Parkinson disease: paradigm shifts and future prospects
-
Farrer M.J. Genetics of Parkinson disease: paradigm shifts and future prospects. Nat. Rev. Genet. 2006, 7:306-318.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 306-318
-
-
Farrer, M.J.1
-
2
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N. Engl. J. Med. 1998, 339:1044-1053.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
3
-
-
37149006535
-
Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies
-
Lim K.L. Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies. Expert Rev. Proteomics 2007, 4:769-781.
-
(2007)
Expert Rev. Proteomics
, vol.4
, pp. 769-781
-
-
Lim, K.L.1
-
4
-
-
0034065822
-
Ubiquitin-mediated proteolysis: biological regulation via destruction
-
Ciechanover A., Orian A., Schwartz A.L. Ubiquitin-mediated proteolysis: biological regulation via destruction. Bioessays 2000, 22:442-451.
-
(2000)
Bioessays
, vol.22
, pp. 442-451
-
-
Ciechanover, A.1
Orian, A.2
Schwartz, A.L.3
-
5
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito R.R. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol. 2000, 10:524-530.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
6
-
-
0344011981
-
RING finger 1 mutations in Parkin produce altered localization of the protein
-
Cookson M.R., Lockhart P.J., McLendon C., O'Farrell C., Schlossmacher M., Farrer M.J. RING finger 1 mutations in Parkin produce altered localization of the protein. Hum. Mol. Genet. 2003, 12:2957-2965.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2957-2965
-
-
Cookson, M.R.1
Lockhart, P.J.2
McLendon, C.3
O'Farrell, C.4
Schlossmacher, M.5
Farrer, M.J.6
-
7
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
-
Chung K.K., Zhang Y., Lim K.L., Tanaka Y., Huang H., Gao J., Ross C.A., Dawson V.L., Dawson T.M. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med. 2001, 7:1144-1150.
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
8
-
-
3142724742
-
UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease
-
Ardley H.C., Scott G.B., Rose S.A., Tan N.G., Robinson P.A. UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease. J. Neurochem. 2004, 90:379-391.
-
(2004)
J. Neurochem.
, vol.90
, pp. 379-391
-
-
Ardley, H.C.1
Scott, G.B.2
Rose, S.A.3
Tan, N.G.4
Robinson, P.A.5
-
9
-
-
1042266326
-
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective
-
Tanaka M., Kim Y.M., Lee G., Junn E., Iwatsubo T., Mouradian M.M. Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J. Biol. Chem. 2004, 279:4625-4631.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4625-4631
-
-
Tanaka, M.1
Kim, Y.M.2
Lee, G.3
Junn, E.4
Iwatsubo, T.5
Mouradian, M.M.6
-
10
-
-
10744220754
-
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration
-
Corti O., Hampe C., Koutnikova H., Darios F., Jacquier S., Prigent A., Robinson J.C., Pradier L., Ruberg M., Mirande M., Hirsch E., Rooney T., Fournier A., Brice A. The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. Hum. Mol. Genet. 2003, 12:1427-1437.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1427-1437
-
-
Corti, O.1
Hampe, C.2
Koutnikova, H.3
Darios, F.4
Jacquier, S.5
Prigent, A.6
Robinson, J.C.7
Pradier, L.8
Ruberg, M.9
Mirande, M.10
Hirsch, E.11
Rooney, T.12
Fournier, A.13
Brice, A.14
-
11
-
-
0344466781
-
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
-
Garcia-Mata R., Bebok Z., Sorscher E.J., Sztul E.S. Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. J. Cell Biol. 1999, 146:1239-1254.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1239-1254
-
-
Garcia-Mata, R.1
Bebok, Z.2
Sorscher, E.J.3
Sztul, E.S.4
-
12
-
-
39049148153
-
Aggresome formation and neurodegenerative diseases: therapeutic implications
-
Olzmann J.A., Li L., Chin L.S. Aggresome formation and neurodegenerative diseases: therapeutic implications. Curr. Med. Chem. 2008, 15:47-60.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 47-60
-
-
Olzmann, J.A.1
Li, L.2
Chin, L.S.3
-
13
-
-
0037423745
-
Identification of a novel gene linked to parkin via a bi-directional promoter
-
West A.B., Lockhart P.J., O'Farell C., Farrer M.J. Identification of a novel gene linked to parkin via a bi-directional promoter. J. Mol. Biol. 2003, 326:11-19.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 11-19
-
-
West, A.B.1
Lockhart, P.J.2
O'Farell, C.3
Farrer, M.J.4
-
14
-
-
0347064343
-
A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death
-
Imai Y., Soda M., Murakami T., Shoji M., Abe K., Takahashi R. A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. J. Biol. Chem. 2003, 278:51901-51910.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51901-51910
-
-
Imai, Y.1
Soda, M.2
Murakami, T.3
Shoji, M.4
Abe, K.5
Takahashi, R.6
-
15
-
-
0037370482
-
Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population
-
Mira M.T., Alcais A., Van Thuc N., Thai V.H., Huong N.T., Ba N.N., Verner A., Hudson T.J., Abel L., Schurr E. Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population. Nat. Genet. 2003, 33:412-415.
-
(2003)
Nat. Genet.
, vol.33
, pp. 412-415
-
-
Mira, M.T.1
Alcais, A.2
Van Thuc, N.3
Thai, V.H.4
Huong, N.T.5
Ba, N.N.6
Verner, A.7
Hudson, T.J.8
Abel, L.9
Schurr, E.10
-
16
-
-
1842441089
-
It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG)
-
Lockhart P.J., O'Farrell C.A., Farrer M.J. It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG). Mov. Disord. 2004, 19:101-104.
-
(2004)
Mov. Disord.
, vol.19
, pp. 101-104
-
-
Lockhart, P.J.1
O'Farrell, C.A.2
Farrer, M.J.3
-
17
-
-
2942592126
-
Deletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutant
-
Lorenzetti D., Bishop C.E., Justice M.J. Deletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutant. Proc. Natl. Acad. Sci. USA 2004, 101:8402-8407.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8402-8407
-
-
Lorenzetti, D.1
Bishop, C.E.2
Justice, M.J.3
-
18
-
-
10744220764
-
Susceptibility to leprosy is associated with PARK2 and PACR
-
Mira M.T., Alcais A., Nguyen V.T., Moraes M.O., Di Flumeri C., Vu H.T., Mai C.P., Nguyen T.H., Nguyen N.B., Pham X.K., Sarno E.N., Alter A., Montpetit A., Moraes M.E., Moraes J.R., Dore C., Gallant C.J., Lepage P., Verner A., Van De Vosse E., Hudson T.J., Abel L., Schurr E. Susceptibility to leprosy is associated with PARK2 and PACR. Nature 2004, 427:636-640.
-
(2004)
Nature
, vol.427
, pp. 636-640
-
-
Mira, M.T.1
Alcais, A.2
Nguyen, V.T.3
Moraes, M.O.4
Di Flumeri, C.5
Vu, H.T.6
Mai, C.P.7
Nguyen, T.H.8
Nguyen, N.B.9
Pham, X.K.10
Sarno, E.N.11
Alter, A.12
Montpetit, A.13
Moraes, M.E.14
Moraes, J.R.15
Dore, C.16
Gallant, C.J.17
Lepage, P.18
Verner, A.19
Van De Vosse, E.20
Hudson, T.J.21
Abel, L.22
Schurr, E.23
more..
-
19
-
-
20044386298
-
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
-
Lim K.L., Chew K.C., Tan J.M., Wang C., Chung K.K., Zhang Y., Tanaka Y., Smith W., Engelender S., Ross C.A., Dawson V.L., Dawson T.M. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. J. Neurosci. 2005, 25:2002-2009.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2002-2009
-
-
Lim, K.L.1
Chew, K.C.2
Tan, J.M.3
Wang, C.4
Chung, K.K.5
Zhang, Y.6
Tanaka, Y.7
Smith, W.8
Engelender, S.9
Ross, C.A.10
Dawson, V.L.11
Dawson, T.M.12
-
20
-
-
20444451210
-
Parkin stabilizes microtubules through strong binding mediated by three independent domains
-
Yang F., Jiang Q., Zhao J., Ren Y., Sutton M.D., Feng J. Parkin stabilizes microtubules through strong binding mediated by three independent domains. J. Biol. Chem. 2005, 280:17154-17162.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17154-17162
-
-
Yang, F.1
Jiang, Q.2
Zhao, J.3
Ren, Y.4
Sutton, M.D.5
Feng, J.6
-
21
-
-
38049014824
-
Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway
-
Olzmann J.A., Chin L.S. Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway. Autophagy 2008, 4:85-87.
-
(2008)
Autophagy
, vol.4
, pp. 85-87
-
-
Olzmann, J.A.1
Chin, L.S.2
-
22
-
-
34447647666
-
Parkin Co-Regulated Gene (PACRG) is regulated by the ubiquitin-proteasomal system and is present in the pathological features of Parkinsonian diseases
-
Taylor J.M., Song Y.J., Huang Y., Farrer M.J., Delatycki M.B., Halliday G.M., Lockhart P.J. Parkin Co-Regulated Gene (PACRG) is regulated by the ubiquitin-proteasomal system and is present in the pathological features of Parkinsonian diseases. Neurobiol. Dis. 2007, 27:238-247.
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 238-247
-
-
Taylor, J.M.1
Song, Y.J.2
Huang, Y.3
Farrer, M.J.4
Delatycki, M.B.5
Halliday, G.M.6
Lockhart, P.J.7
-
23
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence N.F., Sampat R.M., Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 2001, 292:1552-1555.
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
24
-
-
40849133780
-
Regional and cellular localisation of Parkin Co-Regulated Gene in developing and adult mouse brain
-
Brody K.M., Taylor J.M., Wilson G.R., Delatycki M.B., Lockhart P.J. Regional and cellular localisation of Parkin Co-Regulated Gene in developing and adult mouse brain. Brain Res. 2008, 1201:177-186.
-
(2008)
Brain Res.
, vol.1201
, pp. 177-186
-
-
Brody, K.M.1
Taylor, J.M.2
Wilson, G.R.3
Delatycki, M.B.4
Lockhart, P.J.5
-
25
-
-
0344874551
-
Emerging role for autophagy in the removal of aggresomes in Schwann cells
-
Fortun J., Dunn W.A., Joy S., Li J., Notterpek L. Emerging role for autophagy in the removal of aggresomes in Schwann cells. J. Neurosci. 2003, 23:10672-10680.
-
(2003)
J. Neurosci.
, vol.23
, pp. 10672-10680
-
-
Fortun, J.1
Dunn, W.A.2
Joy, S.3
Li, J.4
Notterpek, L.5
-
26
-
-
84934438243
-
Fine structure of the autophagosome
-
Eskelinen E.L. Fine structure of the autophagosome. Methods Mol. Biol. 2008, 445:11-28.
-
(2008)
Methods Mol. Biol.
, vol.445
, pp. 11-28
-
-
Eskelinen, E.L.1
-
27
-
-
13244249799
-
Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death
-
Taylor J.M., Ali U., Iannello R.C., Hertzog P., Crack P.J. Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death. J. Neurochem. 2005, 92:283-293.
-
(2005)
J. Neurochem.
, vol.92
, pp. 283-293
-
-
Taylor, J.M.1
Ali, U.2
Iannello, R.C.3
Hertzog, P.4
Crack, P.J.5
-
28
-
-
0347917234
-
Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival
-
Muqit M.M., Davidson S.M., Payne Smith M.D., MacCormac L.P., Kahns S., Jensen P.H., Wood N.W., Latchman D.S. Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Hum. Mol. Genet. 2004, 13:117-135.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 117-135
-
-
Muqit, M.M.1
Davidson, S.M.2
Payne Smith, M.D.3
MacCormac, L.P.4
Kahns, S.5
Jensen, P.H.6
Wood, N.W.7
Latchman, D.S.8
-
29
-
-
2942518500
-
DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function
-
Lockhart P.J., Lincoln S., Hulihan M., Kachergus J., Wilkes K., Bisceglio G., Mash D.C., Farrer M.J. DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function. J. Med. Genet. 2004, 41:e22.
-
(2004)
J. Med. Genet.
, vol.41
-
-
Lockhart, P.J.1
Lincoln, S.2
Hulihan, M.3
Kachergus, J.4
Wilkes, K.5
Bisceglio, G.6
Mash, D.C.7
Farrer, M.J.8
-
30
-
-
70450161398
-
Oxidative stress impairs the heat stress response and delays unfolded protein recovery
-
Adachi M., Liu Y., Fujii K., Calderwood S.K., Nakai A., Imai K., Shinomura Y. Oxidative stress impairs the heat stress response and delays unfolded protein recovery. PLoS One 2009, 4:e7719.
-
(2009)
PLoS One
, vol.4
-
-
Adachi, M.1
Liu, Y.2
Fujii, K.3
Calderwood, S.K.4
Nakai, A.5
Imai, K.6
Shinomura, Y.7
-
31
-
-
48249084875
-
Autophagy-mediated clearance of aggresomes is not a universal phenomenon
-
E.S. Wong, J.M. Tan, W.E. Soong, K. Hussein, N. Nukina, V.L. Dawson, T.M. Dawson, A.M. Cuervo, K.L. Lim, Autophagy-mediated clearance of aggresomes is not a universal phenomenon, Hum. Mol. Genet. (2008).
-
(2008)
Hum. Mol. Genet.
-
-
Wong, E.S.1
Tan, J.M.2
Soong, W.E.3
Hussein, K.4
Nukina, N.5
Dawson, V.L.6
Dawson, T.M.7
Cuervo, A.M.8
Lim, K.L.9
-
32
-
-
33846320884
-
The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones
-
Fortun J., Verrier J.D., Go J.C., Madorsky I., Dunn W.A., Notterpek L. The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones. Neurobiol. Dis. 2007, 25:252-265.
-
(2007)
Neurobiol. Dis.
, vol.25
, pp. 252-265
-
-
Fortun, J.1
Verrier, J.D.2
Go, J.C.3
Madorsky, I.4
Dunn, W.A.5
Notterpek, L.6
-
33
-
-
0023065242
-
Intracellular protein catabolism and its control during nutrient deprivation and supply
-
Mortimore G.E., Poso A.R. Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu. Rev. Nutr. 1987, 7:539-564.
-
(1987)
Annu. Rev. Nutr.
, vol.7
, pp. 539-564
-
-
Mortimore, G.E.1
Poso, A.R.2
-
34
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T., Hall M.N. TOR, a central controller of cell growth. Cell 2000, 103:253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
35
-
-
34248583762
-
Methods for monitoring autophagy from yeast to human
-
Klionsky D.J., Cuervo A.M., Seglen P.O. Methods for monitoring autophagy from yeast to human. Autophagy 2007, 3:181-206.
-
(2007)
Autophagy
, vol.3
, pp. 181-206
-
-
Klionsky, D.J.1
Cuervo, A.M.2
Seglen, P.O.3
-
36
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding W.X., Ni H.M., Gao W., Yoshimori T., Stolz D.B., Ron D., Yin X.M. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am. J. Pathol. 2007, 171:513-524.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
37
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S., Clausen T.H., Lamark T., Brech A., Bruun J.A., Outzen H., Overvatn A., Bjorkoy G., Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 2007, 282:24131-24145.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
38
-
-
67349098499
-
Analysis of PArkin Co-Regulated Gene in a Taiwanese-Ethnic Chinese cohort with early-onset Parkinson's disease
-
Taylor J.M., Wu R.M., Farrer M.J., Delatycki M.B., Lockhart P.J. Analysis of PArkin Co-Regulated Gene in a Taiwanese-Ethnic Chinese cohort with early-onset Parkinson's disease. Parkinsonism & Related Disord. 2009, 15:417-421.
-
(2009)
Parkinsonism & Related Disord.
, vol.15
, pp. 417-421
-
-
Taylor, J.M.1
Wu, R.M.2
Farrer, M.J.3
Delatycki, M.B.4
Lockhart, P.J.5
-
39
-
-
0242531029
-
Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin
-
Ardley H.C., Scott G.B., Rose S.A., Tan N.G., Markham A.F., Robinson P.A. Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin. Mol. Biol. Cell 2003, 14:4541-4556.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 4541-4556
-
-
Ardley, H.C.1
Scott, G.B.2
Rose, S.A.3
Tan, N.G.4
Markham, A.F.5
Robinson, P.A.6
-
40
-
-
0036797038
-
Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival
-
Lee G., Junn E., Tanaka M., Kim Y.M., Mouradian M.M. Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival. J. Neurochem. 2002, 83:346-352.
-
(2002)
J. Neurochem.
, vol.83
, pp. 346-352
-
-
Lee, G.1
Junn, E.2
Tanaka, M.3
Kim, Y.M.4
Mouradian, M.M.5
-
41
-
-
59349096934
-
The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition
-
Kalveram B., Schmidtke G., Groettrup M. The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition. J. Cell Sci. 2008, 121:4079-4088.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 4079-4088
-
-
Kalveram, B.1
Schmidtke, G.2
Groettrup, M.3
-
42
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Kawaguchi Y., Kovacs J.J., McLaurin A., Vance J.M., Ito A., Yao T.P. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 2003, 115:727-738.
-
(2003)
Cell
, vol.115
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.P.6
-
43
-
-
15444372240
-
The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation
-
Burnett B.G., Pittman R.N. The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation. Proc. Natl. Acad. Sci. USA 2005, 102:4330-4335.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4330-4335
-
-
Burnett, B.G.1
Pittman, R.N.2
-
44
-
-
33751514845
-
The UBL domain of PLIC-1 regulates aggresome formation
-
Heir R., Ablasou C., Dumontier E., Elliott M., Fagotto-Kaufmann C., Bedford F.K. The UBL domain of PLIC-1 regulates aggresome formation. EMBO Rep. 2006, 7:1252-1258.
-
(2006)
EMBO Rep.
, vol.7
, pp. 1252-1258
-
-
Heir, R.1
Ablasou, C.2
Dumontier, E.3
Elliott, M.4
Fagotto-Kaufmann, C.5
Bedford, F.K.6
-
45
-
-
58149465766
-
A critical role for CHIP in the aggresome pathway
-
Sha Y., Pandit L., Zeng S., Eissa N.T. A critical role for CHIP in the aggresome pathway. Mol. Cell. Biol. 2009, 29:116-128.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 116-128
-
-
Sha, Y.1
Pandit, L.2
Zeng, S.3
Eissa, N.T.4
-
46
-
-
42049096115
-
Parkin-co-regulated gene (PACRG) product interacts with tubulin and microtubules
-
Ikeda T. Parkin-co-regulated gene (PACRG) product interacts with tubulin and microtubules. FEBS Lett. 2008, 582:1413-1418.
-
(2008)
FEBS Lett.
, vol.582
, pp. 1413-1418
-
-
Ikeda, T.1
-
47
-
-
0038493550
-
Characterization of chronic low-level proteasome inhibition on neural homeostasis
-
Ding Q., Dimayuga E., Martin S., Bruce-Keller A.J., Nukala V., Cuervo A.M., Keller J.N. Characterization of chronic low-level proteasome inhibition on neural homeostasis. J. Neurochem. 2003, 86:489-497.
-
(2003)
J. Neurochem.
, vol.86
, pp. 489-497
-
-
Ding, Q.1
Dimayuga, E.2
Martin, S.3
Bruce-Keller, A.J.4
Nukala, V.5
Cuervo, A.M.6
Keller, J.N.7
-
48
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey U.B., Nie Z., Batlevi Y., McCray B.A., Ritson G.P., Nedelsky N.B., Schwartz S.L., DiProspero N.A., Knight M.A., Schuldiner O., Padmanabhan R., Hild M., Berry D.L., Garza D., Hubbert C.C., Yao T.P., Baehrecke E.H., Taylor J.P. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007, 447:859-863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
DiProspero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
49
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M., Waguri S., Chiba T., Murata S., Iwata J., Tanida I., Ueno T., Koike M., Uchiyama Y., Kominami E., Tanaka K. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006, 441:880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
Tanaka, K.11
-
50
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T., Nakamura K., Matsui M., Yamamoto A., Nakahara Y., Suzuki-Migishima R., Yokoyama M., Mishima K., Saito I., Okano H., Mizushima N. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006, 441:885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
51
-
-
8344242220
-
Autophagy in health and disease: a double-edged sword
-
Shintani T., Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 2004, 306:990-995.
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
52
-
-
0041589248
-
Alpha-synuclein is degraded by both autophagy and the proteasome
-
Webb J.L., Ravikumar B., Atkins J., Skepper J.N., Rubinsztein D.C. Alpha-synuclein is degraded by both autophagy and the proteasome. J. Biol. Chem. 2003, 278:25009-25013.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
53
-
-
0036566266
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
Ravikumar B., Duden R., Rubinsztein D.C. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum. Mol. Genet. 2002, 11:1107-1117.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
54
-
-
34548851476
-
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
-
Olzmann J.A., Li L., Chudaev M.V., Chen J., Perez F.A., Palmiter R.D., Chin L.S. Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. J. Cell Biol. 2007, 178:1025-1038.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 1025-1038
-
-
Olzmann, J.A.1
Li, L.2
Chudaev, M.V.3
Chen, J.4
Perez, F.A.5
Palmiter, R.D.6
Chin, L.S.7
-
55
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D., Tanaka A., Suen D.F., Youle R.J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 2008, 183:795-803.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
56
-
-
79960407069
-
Parkin interacts with Ambra1 to induce mitophagy
-
Van Humbeeck C., Cornelissen T., Hofkens H., Mandemakers W., Gevaert K., De Strooper B., Vandenberghe W. Parkin interacts with Ambra1 to induce mitophagy. J. Neurosci. 2011, 31:10249-10261.
-
(2011)
J. Neurosci.
, vol.31
, pp. 10249-10261
-
-
Van Humbeeck, C.1
Cornelissen, T.2
Hofkens, H.3
Mandemakers, W.4
Gevaert, K.5
De Strooper, B.6
Vandenberghe, W.7
-
57
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
Chan N.C., Salazar A.M., Pham A.H., Sweredoski M.J., Kolawa N.J., Graham R.L., Hess S., Chan D.C. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet. 2011, 20:1726-1737.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
Hess, S.7
Chan, D.C.8
|