메뉴 건너뛰기




Volumn 152, Issue 2, 2012, Pages 277-285

Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; INITIATION FACTOR 4E BINDING PROTEIN 1; K RAS PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CATALYTIC ALPHA PROTEIN; PHOSPHOTRANSFERASE; PROTEIN KINASE B; RAS PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84864199921     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2012.05.006     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society Atlanta (GA)
    • Cancer facts & figures 2011 2011 American Cancer Society Atlanta (GA)
    • (2011) Cancer Facts & Figures 2011
  • 2
    • 83255192273 scopus 로고    scopus 로고
    • Trends in incidence, treatment and survival of patients with stage IV colorectal cancer: A population-based series
    • A.E. van der Pool, R.A. Damhuis, J.N. Ijzermans, J.H. de Wilt, A.M. Eggermont, and R. Kranse Trends in incidence, treatment and survival of patients with stage IV colorectal cancer: a population-based series Colorectal Dis 14 2012 56 61
    • (2012) Colorectal Dis , vol.14 , pp. 56-61
    • Van Der Pool, A.E.1    Damhuis, R.A.2    Ijzermans, J.N.3    De Wilt, J.H.4    Eggermont, A.M.5    Kranse, R.6
  • 3
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • L.C. Cantley The phosphoinositide 3-kinase pathway Science 296 2002 1655 1657
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 6
    • 73149122504 scopus 로고    scopus 로고
    • Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer
    • P. Gulhati, Q. Cai, J. Li, J. Liu, P.G. Rychahou, and S. Qiu Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer Clin Cancer Res 15 2009 7207 7216
    • (2009) Clin Cancer Res , vol.15 , pp. 7207-7216
    • Gulhati, P.1    Cai, Q.2    Li, J.3    Liu, J.4    Rychahou, P.G.5    Qiu, S.6
  • 7
    • 77952311165 scopus 로고    scopus 로고
    • Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer
    • S.M. Johnson, P. Gulhati, B.A. Rampy, Y. Han, P.G. Rychahou, and H.Q. Doan Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer J Am Coll Surg 210 2010 767 768
    • (2010) J Am Coll Surg , vol.210 , pp. 767-768
    • Johnson, S.M.1    Gulhati, P.2    Rampy, B.A.3    Han, Y.4    Rychahou, P.G.5    Doan, H.Q.6
  • 8
    • 79955486858 scopus 로고    scopus 로고
    • MTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways
    • P. Gulhati, K.A. Bowen, J. Liu, P.D. Stevens, P.G. Rychahou, and M. Chen mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways Cancer Res 71 2011 3246 3256
    • (2011) Cancer Res , vol.71 , pp. 3246-3256
    • Gulhati, P.1    Bowen, K.A.2    Liu, J.3    Stevens, P.D.4    Rychahou, P.G.5    Chen, M.6
  • 9
    • 33745325973 scopus 로고    scopus 로고
    • Targeted molecular therapy of the PI3K pathway: Therapeutic significance of PI3K subunit targeting in colorectal carcinoma
    • P.G. Rychahou, L.N. Jackson, S.R. Silva, S. Rajaraman, and B.M. Evers Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma Ann Surg 243 2006 833 842
    • (2006) Ann Surg , vol.243 , pp. 833-842
    • Rychahou, P.G.1    Jackson, L.N.2    Silva, S.R.3    Rajaraman, S.4    Evers, B.M.5
  • 10
    • 58149503692 scopus 로고    scopus 로고
    • Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis
    • P.G. Rychahou, J. Kang, P. Gulhati, H.Q. Doan, L.A. Chen, and S.Y. Xiao Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis Proc Natl Acad Sci U S A 105 2008 20315 20320
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20315-20320
    • Rychahou, P.G.1    Kang, J.2    Gulhati, P.3    Doan, H.Q.4    Chen, L.A.5    Xiao, S.Y.6
  • 12
    • 78049341541 scopus 로고    scopus 로고
    • Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
    • W. De Roock, D.J. Jonker, F. Di Nicolantonio, A. Sartore-Bianchi, D. Tu, and S. Siena Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab JAMA 304 2010 1812 1820
    • (2010) JAMA , vol.304 , pp. 1812-1820
    • De Roock, W.1    Jonker, D.J.2    Di Nicolantonio, F.3    Sartore-Bianchi, A.4    Tu, D.5    Siena, S.6
  • 13
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • R.J. Shaw, and L.C. Cantley Ras, PI(3)K and mTOR signalling controls tumour cell growth Nature 441 2006 424 430
    • (2006) Nature , vol.441 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 14
    • 77954296394 scopus 로고    scopus 로고
    • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
    • Q.B. She, E. Halilovic, Q. Ye, W. Zhen, S. Shirasawa, and T. Sasazuki 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors Cancer Cell 18 2010 39 51
    • (2010) Cancer Cell , vol.18 , pp. 39-51
    • She, Q.B.1    Halilovic, E.2    Ye, Q.3    Zhen, W.4    Shirasawa, S.5    Sasazuki, T.6
  • 16
    • 33750450911 scopus 로고    scopus 로고
    • RNA interference: Mechanisms of action and therapeutic consideration
    • P.G. Rychahou, L.N. Jackson, B.J. Farrow, and B.M. Evers RNA interference: mechanisms of action and therapeutic consideration Surgery 140 2006 719 725
    • (2006) Surgery , vol.140 , pp. 719-725
    • Rychahou, P.G.1    Jackson, L.N.2    Farrow, B.J.3    Evers, B.M.4
  • 18
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • M.E. Davis, J.E. Zuckerman, C.H. Choi, D. Seligson, A. Tolcher, and C.A. Alabi Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles Nature 464 2010 1067 1070
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1    Zuckerman, J.E.2    Choi, C.H.3    Seligson, D.4    Tolcher, A.5    Alabi, C.A.6
  • 19
    • 24344482476 scopus 로고    scopus 로고
    • Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)
    • P.G. Rychahou, C.A. Murillo, and B.M. Evers Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL) Surgery 138 2005 391 397
    • (2005) Surgery , vol.138 , pp. 391-397
    • Rychahou, P.G.1    Murillo, C.A.2    Evers, B.M.3
  • 21
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • S. Shirasawa, M. Furuse, N. Yokoyama, and T. Sasazuki Altered growth of human colon cancer cell lines disrupted at activated Ki-ras Science 260 1993 85 88
    • (1993) Science , vol.260 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 22
    • 50949104555 scopus 로고    scopus 로고
    • Response and determinants of cancer cell susceptibility to PI3K inhibitors: Combined targeting of PI3K and Mek1 as an effective anticancer strategy
    • K. Yu, L. Toral-Barza, C. Shi, W.G. Zhang, and A. Zask Response and determinants of cancer cell susceptibility to PI3K inhibitors: combined targeting of PI3K and Mek1 as an effective anticancer strategy Cancer Biol Ther 7 2008 307 315
    • (2008) Cancer Biol Ther , vol.7 , pp. 307-315
    • Yu, K.1    Toral-Barza, L.2    Shi, C.3    Zhang, W.G.4    Zask, A.5
  • 23
    • 0032834055 scopus 로고    scopus 로고
    • EIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
    • A.C. Gingras, B. Raught, and N. Sonenberg eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation Annu Rev Biochem 68 1999 913 963
    • (1999) Annu Rev Biochem , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 24
    • 34548028705 scopus 로고    scopus 로고
    • 4E-binding protein 1: A key molecular "funnel factor" in human cancer with clinical implications
    • G. Armengol, F. Rojo, J. Castellvi, C. Iglesias, M. Cuatrecasas, and B. Pons 4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications Cancer Res 67 2007 7551 7555
    • (2007) Cancer Res , vol.67 , pp. 7551-7555
    • Armengol, G.1    Rojo, F.2    Castellvi, J.3    Iglesias, C.4    Cuatrecasas, M.5    Pons, B.6
  • 25
    • 77949519818 scopus 로고    scopus 로고
    • Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer
    • K.L. Kahn, J.L. Adams, J.C. Weeks, E.A. Chrischilles, D. Schrag, and J.Z. Ayanian Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer JAMA 303 2010 1037 1045
    • (2010) JAMA , vol.303 , pp. 1037-1045
    • Kahn, K.L.1    Adams, J.L.2    Weeks, J.C.3    Chrischilles, E.A.4    Schrag, D.5    Ayanian, J.Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.