Enhanced oral bioavailability of novel mucoadhesive pellets containing valsartan prepared by a dry powder-coating technique

International Journal of Pharmaceutics

Volumn 434, Issue 1-2, 2012, Pages 325-333

  Cao, Qing Ri ^a   Liu, Yan ^a   Xu, Wei Juan ^a   Lee, Beom Jin ^b   Yang, Mingshi ^c   Cui, Jing Hao ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Ajou University   (South Korea)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Bioavailability; Delayed GI transit; Dry powder coating; Mucoadhesive pellet; Rapid drug release; Valsartan

Indexed keywords

CARBOMER; DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE; VALSARTAN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG COATING; DRUG RELEASE; GASTROINTESTINAL TRANSIT; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PH; PHYSICOCHEMICAL MODEL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ACRYLIC RESINS; ADHESIVENESS; ADMINISTRATION, ORAL; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; GASTROINTESTINAL TRANSIT; MALE; METHYLCELLULOSE; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TETRAZOLES; VALINE;

EID: 84864129494     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.05.076     Document Type: Article

References (37)

1. A. Bernkop-Schnurch, D. Guggi, and Y. Pinter Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system J. Control. Release 94 2004 177 186
2. Q.R. Cao, H.G. Choi, D.C. Kim, and B.J. Lee Release behavior and photo-image of nifedipine tablet coated with high viscosity grade hydroxypropylmethylcellulose: effect of coating conditions Int. J. Pharm. 274 2004 107 117
3. Q.R. Cao, Y.W. Choi, J.H. Cui, and B.J. Lee Formulation, release characteristics and bioavailability of novel monolithic hydroxypropylmethylcellulose matrix tablets containing acetaminophen J. Control. Release 108 2005 351 361
4. Q.R. Cao, E.S. Lee, Y.J. Choi, C.S. Cho, and B.J. Lee Rumen bypass and biodistribution of l-carnitine from dual-layered coated pellets in cows, in vitro and in vivo Int. J. Pharm. 359 2008 87 93
5. B. Cappello, D.M. Clelia, M. Iervolino, and M. Ageness Improvement of solubility and stability of valsartan by hydroxypropyl beta cyclodextrin J. Incl. Phenom. Macrocycl. Chem. 54 2006 289 294
6. R. Chary, G. Vani, and Y. Rao In vitro and in vivo adhesion testing of mucoadhesive drug delivery systems Drug Dev. Ind. Pharm. 25 1999 685 690
7. R. Dina, and M. Jafari Angiotensin II - receptor antagonist: an overview Am. J. Health Syst. Pharm. 57 2000 1231 1240
8. G. Dumortier, J.L. Grossiord, F. Agnely, and J.C. Chaumeil A review of poloxamer 407 pharmaceutical and pharmacological characteristics Pharm. Res. 23 2006 2709 2728
9. N.S. Ha, T.T.D. Tran, P.H.L. Tran, J.B. Park, and B.J. Lee Dissolution-enhancing mechanism of alkalizers in poloxamer-based solid dispersions and physical mixtures containing poorly water-soluble valsartan Chem. Pharm. Bull. 59 2011 844 850
10. E. Hagesaether, M. Hiorth, and S.A. Sande Mucoadhesion and drug permeability of free mixed films of pectin and chitosan: an in vitro and ex vivo study Eur. J. Pharm. Biopharm. 71 2009 325 331
11. G. Ikinci, S. Senel, C.G. Wilson, and M. Sumnu Development of a buccal bioadhesive nicotine tablet formulation for smoking cessation Int. J. Pharm. 277 2004 173 178
12. F. Kesisoglou, S. Panmai, and Y. Wu Nanosizing-oral formulation development and biopharmaceutical evaluation Adv. Drug Deliv. Rev. 59 2007 631 644
13. B. Laulicht, P. Cheifetz, A. Tripathi, and E. Mathiowitz Are in vivo gastric bioadhesive forces accurately reflected by in vitro experiments? J. Control. Release 134 2009 103 110
14. F. Liu, R. Lizio, C. Meier, H.U. Petereit, P. Blakey, and A.W. Basit A novel concept in enteric coating: a double-coating system providing rapid drug release in the proximal small intestine J. Control. Release 133 2009 119 124
15. J.M. Llabot, R.H. Manzo, and D.A. Allemandi Double-layered mucoadhesive tablets containing nystatin AAPS PharmSciTech. 3 2002 1 6
16. R. Lobenberg, and G.L. Amidon Modern bioavailability, bioequivalence and biopharmaceutics classification system; new scientific approaches to international regulatory standards Eur. J. Pharm. Biopharm. 50 2000 3 12
17. K. Moribe, M. Masaki, R. Kinoshita, J.Y. Zhang, W. Limwikrant, K. Higashi, Y. Tozuka, T. Oguchi, and K. Yamamoto Guest molecular size-dependent inclusion complexation of parabens with cholic acid by cogrinding Int. J. Pharm. 420 2011 191 197
18. Y.J. Park, H.K. Lee, Y.B. Im, W.J. Lee, and H.K. Han Improved pH-independent dissolution and oral absorption of valsartan via the preparation of solid dispersion Arch. Pharm. Res. 33 2010 1235 1240
19. N. Pearnchob, and R. Bodmeier Dry polymer powder coating and comparison with conventional liquid-based coatings for Eudragit® RS, ethylcellulose and shellac Eur. J. Pharm. Biopharm. 56 2003 363 369
20. L. Perioli, V. Ambrogi, C. Pagano, E. Massetti, and C. Rossi New solid mucoadhesive systems for benzydamine vaginal administration Colloid Surf. B 84 2011 413 420
21. L. Perioli, V. Ambrogi, D. Rubini, S. Giovagnoli, M. Ricci, P. Blasi, and C. Rossi Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease J. Control. Release 95 2004 521 533
22. A. Petrovic, N. Cvetkovic, S. Ibric, S. Trajkovic, Z. Djuric, D. Popadic, and R. Popovic Application of mixture experimental design in the formulation and optimization of matrix tablets containing carbomer and hydroxypropyl- methylcellulose Arch. Pharm. Res. 32 2009 1767 1774
23. J.S. Piao, J.E. Lee, K.Y. Weon, D.W. Kim, J.S. Lee, J.D.S. Park, Y. Nishiyama, I. Fukui, and J.S. Kim Development of novel mucoadhesive pellets of metformin hydrochloride Arch. Pharm. Res. 32 2009 391 397
24. N. Pravin, A. Babasaheb, D. Neha, K. Vilasrao, and H. Rajashree Solid state characterization of the inclusion complex of valsartan with methyl β-cyclodextrin J. Incl. Phenom. Macrocycl. Chem. 65 2009 377 383
25. A.R. Shrivastava, B. Ursekar, and C.J. Kapadia Design, optimization, preparation and evaluation of dispersion granules of valsartan and formulation into tablets Curr. Drug Deliv. 6 2009 28 37
26. V.R. Sinha, M.K. Agrawal, and R. Kumria Influence of formulation and excipient variables on the pellet properties prepared by extrusion spheronization Curr. Drug Deliv. 2 2005 1 8
27. M. Smikalla, A. Mescher, P. Walzel, and N.A. Urbanetz Impact of excipients on coating efficiency in dry powder coating Int. J. Pharm. 405 2011 122 131
28. A.R. Tapas, P.S. Kawtikwar, and D.M. Sakarkar Spherically agglomerated solid dispersions of valsartan to improve solubility, dissolution rate and micromeritic properties Int. J. Drug Deliv. 2 2010 304 313
29. Tarur, V.R., Sathe, D.G., Mantripragada, N.R., Sawant, K.D., Thoovara, S.K.M., 2008. Process for the preparation of micronized valsartan. WO2008/035364 A2
30. P.H.L. Tran, H.T.T. Tran, and B.J. Lee Modulation of microenvironmental pH and crystallinity of ionizable telmisartan using alkalizers in solid dispersions for controlled release J. Control. Release 129 2008 59 65
31. P.H.L. Tran, T.T.D. Tran, K.H. Lee, D.J. Kim, and B.J. Lee Dissolution-modulating mechanism of pH modifiers in solid dispersion containing weakly acidic or basic drugs with poor water solubility Expert Opin. Drug Deliv. 7 2010 647 661
32. P.H.L. Tran, T.T.D. Tran, J.B. Park, D.H. Min, H.G. Choi, H.K. Han, Y.S. Rhee, and B.J. Lee Investigation of physicochemical factors affecting the stability of a pH-modulated solid dispersion and a tablet during storage Int. J. Pharm. 414 2011 48 55
33. T.T.D. Tran, P.H.L. Tran, J. Lim, J.B. Park, S.K. Choi, and B.J. Lee Physicochemical principles of controlled release solid dispersion containing a poorly water-soluble drug Ther. Deliv. 1 2010 51 62
34. M. Vogt, K. Kunath, and J.B. Dressman Dissolution enhancement of fenofibrate by micronization, cogrinding and spray-drying: comparison with commercial preparations Eur. J. Pharm. Biopharm. 68 2008 283 288
35. L. Wang, and X. Tang A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: design, in vitro and 'in vivo' evaluation Int. J. Pharm. 350 2008 181 187
36. Y.D. Yan, J.H. Sung, K.K. Kim, D.W. Kim, J.O. Kim, B.J. Lee, C.S. Yong, and H.G. Choi Novel valsartan-loaded solid dispersion with enhanced bioavailability and no crystalline changes Int. J. Pharm. 422 2012 202 210
37. Y.Z. Zhang, Z.Z. Zhi, T.Y. Jiang, J.H. Zhang, Z.Y. Wang, and S.L. Wang Spherical mesoporous silica nanoparticles for loading and release of the poorly water-soluble drug telmisartan J. Control. Release 145 2010 257 263