Development of novel mucoadhesive pellets of metformin hydrochloride

Archives of Pharmacal Research

Volumn 32, Issue 3, 2009, Pages 391-397

  Piao, Jingshu ^a   Lee, Ji Eun ^a   Weon, Kwon Yeon ^b   Kim, Dong Wook ^b   Lee, Jung Suk ^c   Park, James D S ^c   Nishiyama, Yuichi ^d   Fukui, Ikuo ^d   Kim, Jin Seok ^a  

^a Sookmyung Women's University   (South Korea)

^b Handok Pharmaceuticals Co Ltd   (South Korea)

^c Richwood Trading and Pharmaceuticals Co Ltd   (South Korea)

^d SHIN ETSU CHEMICAL CO LTD   (Japan)

Author keywords

CF granulator; Metformin hydrochloride; Mucoadhesion; Pellets; Polymer; Powder layering

Indexed keywords

ALGINIC ACID; CARBOMER; HYDROXYMETHYLCELLULOSE; METFORMIN; MUCIN; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRIFUGATION; CONTROLLED STUDY; DISSOLUTION; DRUG DOSAGE FORM; MUCOADHESION; NONHUMAN; RAT; SUSTAINED DRUG RELEASE; VISCOSITY; ZETA POTENTIAL;

ADHESIVENESS; ALGINATES; ANIMALS; CAPSULES; CARBOXYMETHYLCELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; GLUCURONIC ACID; HARDNESS; HEXURONIC ACIDS; HYPOGLYCEMIC AGENTS; KINETICS; METFORMIN; METHYLCELLULOSE; MUCINS; POLYMERS; POLYVINYLS; POWDERS; RATS; SOLUBILITY; STOMACH; VISCOSITY;

EID: 65449149831     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-1312-0     Document Type: Article

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