Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model

Experimental and Molecular Medicine

Volumn 44, Issue 7, 2012, Pages 448-456

  Kim, In Hee ^a   Kim, Sang Wook ^a   Kim, Seong Hun ^a   Lee, Seung Ok ^a   Lee, Soo Teik ^a   Kim, Dae Ghon ^a   Lee, Mi Jin ^a   Park, Woo Hyun ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Apoptosis; Hepatic stellate cells; Liver cirrhosis; Parthenolide; Reactive oxygen species; Thioacetamide

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; CASPASE 3; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARTHENOLIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; THIOACETAMIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BODY WEIGHT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVATION; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LIVER WEIGHT; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; STELLATE CELL; TREATMENT RESPONSE;

RATTUS; TANACETUM PARTHENIUM;

EID: 84864092038     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2012.44.7.051     Document Type: Article

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