Mechanical failure, stress redistribution, elastase activity and binding site availability on elastin during the progression of emphysema

Pulmonary Pharmacology and Therapeutics

Volumn 25, Issue 4, 2012, Pages 268-275

  Suki, Béla ^a   Jesudason, Rajiv ^a   Sato, Susumu ^a   Parameswaran, Harikrishnan ^a   Araujo, Ascanio D ^a,b   Majumdar, Arnab ^a   Allen, Philip G ^a   Bartolák Suki, Erzsébet ^a  

^a Boston University   (United States)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Binding; Collagen; Elastin; Off rate; Prestress

Indexed keywords

ELASTASE; ELASTIN;

ARTICLE; BINDING SITE; DISEASE COURSE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME RELEASE; HUMAN; LUNG EMPHYSEMA; LUNG PARENCHYMA; MECHANICAL STRESS; MECHANOTRANSDUCTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; BIOMECHANICS; COLLAGEN; DISEASE PROGRESSION; ELASTIN; EXTRACELLULAR MATRIX; HUMANS; LUNG; MECHANOTRANSDUCTION, CELLULAR; PANCREATIC ELASTASE; PULMONARY ALVEOLI; PULMONARY EMPHYSEMA; SWINE;

EID: 84864062037     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2011.04.027     Document Type: Article

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