Molecular mechanochemistry: Low force switch slows enzymatic cleavage of human type I collagen monomer

Journal of the American Chemical Society

Volumn 133, Issue 11, 2011, Pages 4073-4078

  Camp, Robert J ^a   Liles, Melody ^a,b   Beale, John ^a   Saeidi, Nima ^a   Flynn, Brendan P ^a   Moore, Elias ^a   Murthy, Shashi K ^a   Ruberti, Jeffrey W ^a  

^a Northeastern University   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN MONOMERS; COLLAGENASE; ENZYMATIC CLEAVAGE; ENZYMATIC DEGRADATION; FIBRILLAR COLLAGENS; HELICAL DOMAINS; MECHANICAL FORCE; MECHANICAL STATE; MECHANO-CHEMISTRY; MECHANOCHEMICAL REACTIONS; MECHANOCHEMICALS; MOLECULAR ARCHITECTURE; MOLECULAR STABILITY; SINGLE MOLECULE; STRUCTURAL MECHANISMS; TENSILE LOADS; TYPE I COLLAGEN;

ANIMALS; BIODEGRADATION; DEGRADATION; ENZYMES; MECHANICAL ENGINEERING; MONOMERS;

COLLAGEN;

CLOSTRIDIOPEPTIDASE A; COLLAGEN TYPE 1; MONOMER;

ARTICLE; CHEMICAL REACTION; CLOSTRIDIUM HISTOLYTICUM; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; FORCE; MOLECULAR STABILITY; NONHUMAN; TENSION;

COLLAGEN TYPE I; HUMANS; HYDROLYSIS; KINETICS;

EID: 79952750509     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja110098b     Document Type: Article

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