Metabolite profiles reveal energy failure and impaired beta-oxidation in liver of mice with complex iii deficiency due to a bcs1l mutation

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Kotarsky, Heike ^a   Keller, Matthias ^b   Davoudi, Mina ^a   Levéen, Per ^a   Karikoski, Riitta ^c   Enot, David P ^b   Fellman, Vineta ^a,d,e  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^e FOLKHÄLSAN RESEARCH CENTER   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; ADENOSINE PHOSPHATE; AMINO ACID DERIVATIVE; BIOGENIC AMINE; CARBOHYDRATE; FUMARIC ACID; PUTRESCINE; SUCCINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BCS1L GENE; COMPLEX III DEFICIENCY; CONTROLLED STUDY; DISEASE COURSE; END STAGE LIVER DISEASE; FATTY ACID OXIDATION; GENE; GENE MUTATION; HISTOPATHOLOGY; HOMOZYGOTE; IMPAIRED GLUCOSE TOLERANCE; LIVER CELL; MALE; METABOLITE; METABOLOMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS;

ADENOSINE MONOPHOSPHATE; ANIMALS; ANTIOXIDANTS; ELECTRON TRANSPORT COMPLEX III; FUMARATES; HYDROGEN PEROXIDE; LIVER; MASS SPECTROMETRY; MICE; MITOCHONDRIAL DISEASES; MOLECULAR CHAPERONES; MUTATION; OXIDATIVE STRESS; SUCCINIC ACID;

MUS; MUS MUSCULUS;

EID: 84864039418     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041156     Document Type: Article

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