Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research

Analytical Biochemistry

Volumn 406, Issue 2, 2010, Pages 124-131

  Urban, Michael ^a   Enot, David P ^a   Dallmann, Guido ^a   Körner, Lisa ^a   Forcher, Verena ^a   Enoh, Peter ^a   Koal, Therese ^a   Keller, Matthias ^a,b   Deigner, Hans Peter ^a  

^a BIOCRATES LIFE SCIENCES AG   (Austria)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Brain homogenization; Mass spectrometry; Metabolomics; Quantitative analysis

Indexed keywords

BIOMOLECULES; BRAIN; CHEMICAL ANALYSIS; MASS SPECTROMETRY; METABOLITES; PHYSICOCHEMICAL PROPERTIES; TISSUE;

CONCENTRATION-DEPENDENT; EXTRACTION SOLVENTS; ILL POSED PROBLEM; IONIZATION EFFICIENCY; MEASUREMENT PRECISION; METABOLITE CONCENTRATIONS; METABOLOMICS; MULTIPLE OBJECTIVE DECISION;

EXTRACTION;

ACCURACY; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; FINGER DERMATOGLYPHICS; IONIZATION; MASS SPECTROMETRY; METABOLITE; METABOLOMICS; MOLECULAR WEIGHT; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PRODUCTIVITY; QUANTITATIVE ANALYSIS; SOLVENT EXTRACTION;

EID: 77956227446     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2010.07.002     Document Type: Article

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