Insulin enhances glucose-stimulated insulin secretion in healthy humans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 10, 2010, Pages 4770-4775

  Bouche, Clara ^a,b,g   Lopez, Ximena ^a,b,c,h   Fleischman, Amy ^a,b,d   Cypess, Aaron M ^a,b   O'Shea, Sheila ^a   Stefanovski, Darko ^e   Bergman, Richard N ^e   Rogatsky, Eduard ^f   Stein, Daniel T ^f   Kahn, C Ronald ^a,b   Kulkarni, Rohit N ^a,b   Goldfine, Allison B ^a,b  

^a JOSLIN DIABETES CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^g Cochin Hospital ^*  (France)

^h NOVO NORDISK A S   (Denmark)

Author keywords

Beta cell; C peptide; Insulin clearance; Insulin resistance; Type 2 diabetes mellitus

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HORMONE RELEASE; HUMAN; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; ISOTOPE LABELING; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ADULT; BLOOD GLUCOSE; C-PEPTIDE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE; HORMONES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; MALE; METABOLIC CLEARANCE RATE; SINGLE-BLIND METHOD; YOUNG ADULT;

RODENTIA;

EID: 77949535836     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1000002107     Document Type: Article

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