Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging

Aging Cell

Volumn 11, Issue 4, 2012, Pages 704-713

  Wang, Haitao ^a   Chen, Qijun ^a   Lee, Seoung Hoon ^b   Choi, Yongwon ^a   Brad Johnson, Frederick ^a   Pignolo, Robert J ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Wonkwang University   (South Korea)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Aging; Mesenchymal stem cells; Osteoporosis; Telomere; Telomere dysfunction

Indexed keywords

HELICASE; PROTEIN P21; PROTEIN P53; TELOMERASE; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME DEFICIENCY; GROWTH ACCELERATION; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TELOMERE; WESTERN BLOTTING;

AGING, PREMATURE; ANIMALS; CELL AGING; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; FEMALE; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOPOROSIS; RECQ HELICASES; SIGNAL TRANSDUCTION; TELOMERASE; TELOMERE HOMEOSTASIS;

MUS;

EID: 84864020793     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2012.00838.x     Document Type: Article

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