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Volumn 7, Issue 7, 2012, Pages

Central but not systemic administration of ghrelin induces wakefulness in mice

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; NEUROPEPTIDE Y; OREXIN;

EID: 84864015500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041172     Document Type: Article
Times cited : (24)

References (54)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, et al. (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402: 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5
  • 2
    • 77954591294 scopus 로고    scopus 로고
    • Ghrelin: more than endogenous growth hormone secretagogue
    • Kojima M, Kangawa K, (2010) Ghrelin: more than endogenous growth hormone secretagogue. Ann N Y Acad Sci 1200: 140-8.
    • (2010) Ann N Y Acad Sci , vol.1200 , pp. 140-148
    • Kojima, M.1    Kangawa, K.2
  • 3
    • 0037456519 scopus 로고    scopus 로고
    • The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
    • Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, et al. (2003) The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 37: 649-661.
    • (2003) Neuron , vol.37 , pp. 649-661
    • Cowley, M.A.1    Smith, R.G.2    Diano, S.3    Tschöp, M.4    Pronchuk, N.5
  • 4
    • 0034731310 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue
    • Hosoda H, Kojima M, Matsuo H, Kangawa K, (2000) Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun 279(3): 909-13.
    • (2000) Biochem Biophys Res Commun , vol.279 , Issue.3 , pp. 909-913
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3    Kangawa, K.4
  • 5
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
    • Yang J, Brown MS, Liang G, Grishin NV, Goldstein JL, (2008) Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132(3): 387-96.
    • (2008) Cell , vol.132 , Issue.3 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 6
    • 0030762351 scopus 로고    scopus 로고
    • Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
    • Guan XM, Yu H, Palyha OC, McKee KK, Feighner SD, et al. (1997) Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res Mol Brain Res 48: 23-29.
    • (1997) Brain Res Mol Brain Res , vol.48 , pp. 23-29
    • Guan, X.M.1    Yu, H.2    Palyha, O.C.3    McKee, K.K.4    Feighner, S.D.5
  • 7
    • 0035863948 scopus 로고    scopus 로고
    • Comparative distribution of mRNA encoding the growth hormone secretagogue-receptor (GHS-R) in Microcebus murinus (Primate, lemurian) and rat forebrain and pituitary
    • Mitchell V, Bouret S, Beauvillain JC, Schilling A, Perret M, et al. (2001) Comparative distribution of mRNA encoding the growth hormone secretagogue-receptor (GHS-R) in Microcebus murinus (Primate, lemurian) and rat forebrain and pituitary. J Comp Neurol 429: 469-489.
    • (2001) J Comp Neurol , vol.429 , pp. 469-489
    • Mitchell, V.1    Bouret, S.2    Beauvillain, J.C.3    Schilling, A.4    Perret, M.5
  • 9
    • 39149129347 scopus 로고    scopus 로고
    • Autoradiographic analysis of ghrelin receptors in the rat hypothalamus
    • Harrold JA, Dovey T, Cai XJ, Halford JC, Pinkney J, (2008) Autoradiographic analysis of ghrelin receptors in the rat hypothalamus. Brain Res 1196: 59-64.
    • (2008) Brain Res , vol.1196 , pp. 59-64
    • Harrold, J.A.1    Dovey, T.2    Cai, X.J.3    Halford, J.C.4    Pinkney, J.5
  • 10
    • 33947536063 scopus 로고    scopus 로고
    • Physiological, pathological and potential therapeutic roles of ghrelin
    • Leite-Moreira AF, Soares JB, (2007) Physiological, pathological and potential therapeutic roles of ghrelin. Drug Discov Today 12(7-8): 276-88.
    • (2007) Drug Discov Today , vol.12 , Issue.7-8 , pp. 276-288
    • Leite-Moreira, A.F.1    Soares, J.B.2
  • 11
    • 0036787457 scopus 로고    scopus 로고
    • The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
    • Date Y, Murakami N, Toshinai K, Matsukura S, Niijima A, et al. (2002) The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123(4): 1120-8.
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1120-1128
    • Date, Y.1    Murakami, N.2    Toshinai, K.3    Matsukura, S.4    Niijima, A.5
  • 12
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschöp M, Smiley DL, Heiman ML, (2000) Ghrelin induces adiposity in rodents. Nature 407: 908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschöp, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 13
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, et al. (2000) The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141: 4325-4328.
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5
  • 15
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, et al. (2001) A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50: 1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5
  • 16
    • 81755185430 scopus 로고    scopus 로고
    • Neuroendocrine and metabolic activities of ghrelin gene products
    • Baragli A, Lanfranco F, Allasia S, Granata R, Ghigo E, (2011) Neuroendocrine and metabolic activities of ghrelin gene products. Peptides 32: 2323-2332.
    • (2011) Peptides , vol.32 , pp. 2323-2332
    • Baragli, A.1    Lanfranco, F.2    Allasia, S.3    Granata, R.4    Ghigo, E.5
  • 17
    • 79958788035 scopus 로고    scopus 로고
    • Cardiovascular actions of the ghrelin gene-derived peptides and growth hormone-releasing hormone
    • Granata R, Isgaard J, Alloatti G, Ghigo E, (2011) Cardiovascular actions of the ghrelin gene-derived peptides and growth hormone-releasing hormone. Exp Biol Med 236: 505-514.
    • (2011) Exp Biol Med , vol.236 , pp. 505-514
    • Granata, R.1    Isgaard, J.2    Alloatti, G.3    Ghigo, E.4
  • 19
    • 0035133586 scopus 로고    scopus 로고
    • Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin
    • Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, et al. (2001) Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120: 337-345.
    • (2001) Gastroenterology , vol.120 , pp. 337-345
    • Asakawa, A.1    Inui, A.2    Kaga, T.3    Yuzuriha, H.4    Nagata, T.5
  • 20
    • 23044493838 scopus 로고    scopus 로고
    • Peripheral interaction of ghrelin with cholecystokinin on feeding regulation
    • Date Y, Toshinai K, Koda S, Miyazato M, Shimbara T, et al. (2005) Peripheral interaction of ghrelin with cholecystokinin on feeding regulation. Endocrinology 146: 3518-3525.
    • (2005) Endocrinology , vol.146 , pp. 3518-3525
    • Date, Y.1    Toshinai, K.2    Koda, S.3    Miyazato, M.4    Shimbara, T.5
  • 21
    • 33748946416 scopus 로고    scopus 로고
    • Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus
    • Date Y, Shimbara T, Koda S, Toshinai K, Ida T, et al. (2006) Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus. Cell Metab 4(4): 323-31.
    • (2006) Cell Metab , vol.4 , Issue.4 , pp. 323-331
    • Date, Y.1    Shimbara, T.2    Koda, S.3    Toshinai, K.4    Ida, T.5
  • 22
    • 33751120393 scopus 로고    scopus 로고
    • Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat
    • Arnold M, Mura A, Langhans W, Geary N, (2006) Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat. J Neurosci 43: 11052-11060.
    • (2006) J Neurosci , vol.43 , pp. 11052-11060
    • Arnold, M.1    Mura, A.2    Langhans, W.3    Geary, N.4
  • 23
    • 6344267074 scopus 로고    scopus 로고
    • Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation
    • Bodosi B, Gardi J, Hajdu I, Szentirmai E, Obal F Jr, et al. (2004) Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation. Am J Physiol Regul Integr Comp Physiol 287: R1071-R1079.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Bodosi, B.1    Gardi, J.2    Hajdu, I.3    Szentirmai, E.4    Obal Jr., F.5
  • 24
    • 0036218881 scopus 로고    scopus 로고
    • Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats
    • Tolle V, Bassant MH, Zizzari P, Poindessous-Jazat F, Tomasetto C, et al. (2002) Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats. Endocrinology 143: 1353-1361.
    • (2002) Endocrinology , vol.143 , pp. 1353-1361
    • Tolle, V.1    Bassant, M.H.2    Zizzari, P.3    Poindessous-Jazat, F.4    Tomasetto, C.5
  • 25
    • 33646587702 scopus 로고    scopus 로고
    • Ghrelin-induced sleep responses in ad libitum fed and food-restricted rats
    • Szentirmai E, Hajdu I, Obal F Jr, Krueger JM, (2006) Ghrelin-induced sleep responses in ad libitum fed and food-restricted rats. Brain Res 1088: 131-140.
    • (2006) Brain Res , vol.1088 , pp. 131-140
    • Szentirmai, E.1    Hajdu, I.2    Obal Jr., F.3    Krueger, J.M.4
  • 27
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun Y, Wang P, Zheng H, Smith RG, (2004) Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci USA 101: 4679-4684.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 28
    • 84855976058 scopus 로고    scopus 로고
    • Impaired wake-promoting mechanisms in ghrelin receptor deficient mice
    • Esposito M, Pellinen J, Kapás L, Szentirmai É, (2012) Impaired wake-promoting mechanisms in ghrelin receptor deficient mice. Eur. J. Neurosci 35: 233-243.
    • (2012) Eur. J. Neurosci , vol.35 , pp. 233-243
    • Esposito, M.1    Pellinen, J.2    Kapás, L.3    Szentirmai, É.4
  • 29
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun Y, Ahmed S, Smith RG, (2003) Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 23: 7973-7981.
    • (2003) Mol Cell Biol , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 30
    • 69549096259 scopus 로고    scopus 로고
    • The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice
    • Szentirmai É, Kapás L, Sun Y, Smith RG, Krueger JM, (2009) The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice. Proc Natl Acad Sci USA 106: 14069-14074.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14069-14074
    • Szentirmai, É.1    Kapás, L.2    Sun, Y.3    Smith, R.G.4    Krueger, J.M.5
  • 32
    • 75449110717 scopus 로고    scopus 로고
    • Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice
    • Szentirmai É, Kapás L, Sun Y, Smith RG, Krueger JM, (2010) Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice. Am J Physiol Regul Integr Comp Physiol 298: R467-R477.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298
    • Szentirmai, É.1    Kapás, L.2    Sun, Y.3    Smith, R.G.4    Krueger, J.M.5
  • 36
    • 33748362868 scopus 로고    scopus 로고
    • Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward
    • Jerlhag E, Egecioglu E, Dickson SL, Andersson M, Svensson L, et al. (2006) Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward. Addict Biol 11: 45-54.
    • (2006) Addict Biol , vol.11 , pp. 45-54
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Andersson, M.4    Svensson, L.5
  • 37
    • 33745993355 scopus 로고    scopus 로고
    • Mediation of the behavioral, endocrine and thermoregulatory actions of ghrelin
    • Jászberényi M, Bujdosó E, Bagosi Z, Telegdy G, (2006) Mediation of the behavioral, endocrine and thermoregulatory actions of ghrelin. Horm Behav 50: 266-273.
    • (2006) Horm Behav , vol.50 , pp. 266-273
    • Jászberényi, M.1    Bujdosó, E.2    Bagosi, Z.3    Telegdy, G.4
  • 38
    • 33947139281 scopus 로고    scopus 로고
    • Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens
    • Jerlhag E, Egecioglu E, Dickson SL, Douhan A, Svensson L, et al. (2007) Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict Biol 12: 6-16.
    • (2007) Addict Biol , vol.12 , pp. 6-16
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Douhan, A.4    Svensson, L.5
  • 41
    • 77954566931 scopus 로고    scopus 로고
    • The orexin system: roles in sleep/wake regulation
    • Sakurai T, Mieda M, Tsujino N, (2010) The orexin system: roles in sleep/wake regulation. Ann N Y Acad Sci 1200: 149-161.
    • (2010) Ann N Y Acad Sci , vol.1200 , pp. 149-161
    • Sakurai, T.1    Mieda, M.2    Tsujino, N.3
  • 42
    • 0035136970 scopus 로고    scopus 로고
    • From slow waves to sleep homeostasis: new perspectives
    • Borbély AA, (2001) From slow waves to sleep homeostasis: new perspectives. Arch Ital Biol 139(1-2): 53-61.
    • (2001) Arch Ital Biol , vol.139 , Issue.1-2 , pp. 53-61
    • Borbély, A.A.1
  • 44
    • 33947102777 scopus 로고    scopus 로고
    • Ghrelin administered in the early morning increases secretion of cortisol and growth hormone without affecting sleep
    • Kluge M, Schussler P, Zuber V, Yassouridis A, Steiger A, (2007a) Ghrelin administered in the early morning increases secretion of cortisol and growth hormone without affecting sleep. Psychoneuroendocrinology 32: 287-292.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 287-292
    • Kluge, M.1    Schussler, P.2    Zuber, V.3    Yassouridis, A.4    Steiger, A.5
  • 45
    • 36049023512 scopus 로고    scopus 로고
    • Ghrelin enhances the nocturnal secretion of cortisol and growth hormone in young females without influencing sleep
    • Kluge M, Schüssler P, Zuber, Kleyer S, Yassouridis A, et al. (2007b) Ghrelin enhances the nocturnal secretion of cortisol and growth hormone in young females without influencing sleep. Psychoneuroendocrinology 32: 1079-1085.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 1079-1085
    • Kluge, M.1    Schüssler, P.2    Zuber3    Kleyer, S.4    Yassouridis, A.5
  • 46
    • 73949125003 scopus 로고    scopus 로고
    • Ghrelin increases slow wave sleep and stage 2 sleep and decreases stage 1 sleep and REM sleep in elderly men but does not affect sleep in elderly women
    • Kluge M, Gazea M, Schüssler P, Genzel L, Dresler M, et al. (2010) Ghrelin increases slow wave sleep and stage 2 sleep and decreases stage 1 sleep and REM sleep in elderly men but does not affect sleep in elderly women. Psychoneuroendocrinology 35: 297-304.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 297-304
    • Kluge, M.1    Gazea, M.2    Schüssler, P.3    Genzel, L.4    Dresler, M.5
  • 47
    • 0029061494 scopus 로고
    • Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man
    • Frieboes RM, Murck H, Maier P, Schier T, Holsboer F, et al. (1995) Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man. Neuroendocrinology 61: 584-589.
    • (1995) Neuroendocrinology , vol.61 , pp. 584-589
    • Frieboes, R.M.1    Murck, H.2    Maier, P.3    Schier, T.4    Holsboer, F.5
  • 48
    • 0030885174 scopus 로고    scopus 로고
    • Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in man
    • Copinschi G, Leproult R, van Onderbergen A, Caufriez A, Cole KY, et al. (1997) Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in man. Neuroendocrinology 66: 278-286.
    • (1997) Neuroendocrinology , vol.66 , pp. 278-286
    • Copinschi, G.1    Leproult, R.2    van Onderbergen, A.3    Caufriez, A.4    Cole, K.Y.5
  • 49
    • 0031803339 scopus 로고    scopus 로고
    • Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation
    • Moreno-Reyes R, Kerkhofs M, L'Hermite-Baleriaux M, Thorner MO, van Cauter E, et al. (1998) Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation. Am J Physiol 274: E779-E784.
    • (1998) Am J Physiol , vol.274
    • Moreno-Reyes, R.1    Kerkhofs, M.2    L'Hermite-Baleriaux, M.3    Thorner, M.O.4    van Cauter, E.5
  • 50
    • 2642560187 scopus 로고    scopus 로고
    • Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers
    • Frieboes RM, Antonijevic IA, Held K, Murck H, Pollmächer T, et al. (2004) Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers. Psychoneuroendocrinology 29: 851-860.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 851-860
    • Frieboes, R.M.1    Antonijevic, I.A.2    Held, K.3    Murck, H.4    Pollmächer, T.5
  • 53
    • 70349738106 scopus 로고    scopus 로고
    • Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice
    • Blum ID, Patterson Z, Khazall R, Lamont EW, Sleeman MW, et al. (2009) Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice. Neuroscience 164: 351-359.
    • (2009) Neuroscience , vol.164 , pp. 351-359
    • Blum, I.D.1    Patterson, Z.2    Khazall, R.3    Lamont, E.W.4    Sleeman, M.W.5
  • 54
    • 79953127787 scopus 로고    scopus 로고
    • Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice
    • Gunapala KM, Gallardo CM, Hsu CT, Steele AD, (2011) Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice. PLoS One. 6(3): e18377.
    • (2011) PLoS One , vol.6 , Issue.3
    • Gunapala, K.M.1    Gallardo, C.M.2    Hsu, C.T.3    Steele, A.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.