Robust closed-loop minimal sampling method for hiv therapy switching strategies

IEEE Transactions on Biomedical Engineering

Volumn 59, Issue 8, 2012, Pages 2227-2234

  Fabian Cardozo, E ^a   Zurakowski, Ryan ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

Drug resistance; evolutionary modeling; human immunodeficiency virus (HIV); Monte Carlo robustness analysis; ordinary differential equations

Indexed keywords

ANTIRETROVIRALS; ANTIVIRAL THERAPY; CLOSED-LOOP; DISEASE PROGRESSION; DRUG RESISTANCE; DRUG-RESISTANT STRAINS; HIV THERAPY; HUMAN IMMUNODEFICIENCY VIRUS; MEASUREMENT UNCERTAINTY; MONTE CARLO ANALYSIS; NUMBER OF SAMPLES; OPTIMAL SWITCHING; RESISTANT STRAINS; ROBUSTNESS ANALYSIS; SAMPLING ALGORITHM; SAMPLING METHOD; SWITCHING STRATEGIES; TREATMENT FAILURE; VIRAL LOAD;

DISEASE CONTROL; DISEASES; DRUG THERAPY; ORDINARY DIFFERENTIAL EQUATIONS; UNCERTAINTY ANALYSIS; VIRUSES;

SWITCHING;

ALGORITHM; ANTIVIRAL THERAPY; ARTICLE; CLOSED LOOP SAMPLING ALGORITHM; COST BENEFIT ANALYSIS; HISTOGRAM; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONTE CARLO METHOD; RISK ASSESSMENT; SAMPLING; SIMULATION; VIRUS LOAD; VIRUS STRAIN;

ALGORITHMS; ANTI-RETROVIRAL AGENTS; DISEASE PROGRESSION; DRUG MONITORING; DRUG RESISTANCE, VIRAL; HIV; HIV INFECTIONS; HUMANS; MONTE CARLO METHOD; VIRAL LOAD;

EID: 84864016280     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2012.2201479     Document Type: Article

References (20)

1. J. L. Martinez-Cajas and M. A. Wainberg, "Antiretroviral therapy\-Optimal sequencing of therapy to avoid resistance," Drugs, vol. 68,no. 1, pp. 43-72, Jan 2008. (Pubitemid 350275684)
2. M. A. Wainberg and K.-T. Jeang, "25 years of HIV-1 research\-Progress and perspectives," BMCMed., vol. 6,p.31, Jan. 2008.
3. M. A. Thompson, J. A. Aberg, P. Cahn, J. S. G. Montaner, G. Rizzardini, A. Telenti, J. M. Gatell, H. F. Guenthard, S. M. Hammer, M. S. Hirsch, D. M. Jacobsen, P. Reiss, D. D. Richman, P. A. Volberding, P. Yeni, and R. T. Schooley, "Antiretroviral treatment of adult HIV infection 2010 recommendations of the international aids society-usa panel," JAMA\-J. Amer. Med. Assoc., vol. 304, no. 3, pp. 321-333, Jan. 2010.
4. P. Arora and N. M. Dixit, "Timing the emergence of resistance to anti-HIV drugs with large genetic barriers," Plos Comput. Biol., vol. 5, no. 3, Jan. 2009.
5. S. Bonhoeffer and M. A. Nowak, "Pre-existence and emergence of drug re- sistanceinHIV-1 infection," Proc. Biol. Sci., vol. 264, no. 1382,pp. 631- 637, May 1997. (Pubitemid 27241346)
6. R. M. Ribeiro and S. Bonhoeffer, "Production of resistant HIV mutants during antiretroviral therapy," Proc. Natl. Acad. Sci. USA, vol. 97, no. 14, pp. 7681-7686, Jul. 2000. (Pubitemid 30460706)
7. E. Hernandez-Vargas, P. Colaneri, R. Middleton, and F. Blanchini, "Discrete-time control for switched positive systems with application to mitigating viral escape," Int. J. Robust Nonlinear Control, vol. 21, no. 10, pp. 1093-1111, Jul. 2010.
8. J. Martinez-Picado, E. Negredo, L. Ruiz, A. Shintani, C. R. Fumaz, C. Zala, P. Domingo, J. Vilaró, J. M. Llibre, P. Viciana, K. Hertogs, C. Boucher, R. T. D'Aquila, B. Clotet, and SWATCH Study Team, "Alternation of antiretroviral drug regimens for HIV infection. A randomized, controlled trial," Ann. Intern. Med., vol. 139, no. 2, pp. 81-89, Jul. 2003.
9. R. Luo, M. J. Piovoso, J. Martinez-Picado, and R. Zurakowski, "Optimal antiviral switching to minimize resistance risk in HIV therapy," Plos One, vol. 6, no. 11, p. e27047, Jan. 2011.
10. R. Luo, M. Piovoso, and R. Zurakowski, "Modeling-error robustness of a viral-load preconditioning strategy for HIV treatment switching.," in Proc. Amer. Control Conf., 2010, pp. 5155-5160.
11. R. Luo, M. Piovoso, and R. Zurakowski, "A generalized multi-strain model of HIV evolution with implications for drug-resistance management," in Proc.Amer. Control Conf., 2009, pp. 2295-2300.
12. R. Luo, L. Cannon, J. Hernandez, M. J. Piovoso, and R. Zurakowski, "Controlling the evolution of resistance," J. Process. Contr., vol. 21, no. 3, pp. 367-378, Jan. 2011.
13. R. Luo and R. Zurakowski, "A new strategy to decrease risk of resistance emerging during therapy switching in HIV treatment," in Proc. Amer. Control Conf., Jun. 2008, pp. 2112-2117.
14. E. Rosero-Garcia and R. Zurakowski, "Closed-loop minimal sampling method for determining viral-load minima during switching," in Proc. Amer. Control Conf., Jun./Jul., 2010, pp. 460-461.
15. R. Zurakowski, M. Churgin, C. Perez, and M. Rodriguez, "Approximate- model closed-loop minimal sampling method for HIV viral-load minima detection," in Proc. Amer. Control Conf., Jul. 2011, pp. 5418-5419.
16. E. F. Cardozo and R. Zurakowski, "Measurement error robustness of a closed-loop minimal sampling method for HIV therapy switching," in Annu. Int. Conf. IEEEEng. Med. Biol. Soc., Aug./Sep. 2011, pp. 116-119.
17. Y. Iwasa, F. Michor, and M. A. Nowak, "Evolutionary dynamics of invasion and escape," J. Theor. Biol., vol. 226, no. 2, pp. 205-214, Jan. 2004. (Pubitemid 37468399)
18. N. Beerenwinkel, N. Eriksson, and B. Sturmfels, "Evolution on distributive lattices," J. Theor. Biol., vol. 242, no. 2, pp. 409-420, Sep. 2006. (Pubitemid 44232818)
19. L. Ruiz, G. Carcelain, J. Martínez-Picado, S. Frost, S. Marfil, R. Paredes, J. Romeu, E. Ferrer, K. Morales-Lopetegi, B. Autran, and B. Clotet, "HIV dynamics and T-cell immunity after three structured treatment interrup- tions in chronic HIV-1 infection," AIDS, vol. 15, no. 9, pp. F19-F27, Jun. 2001. (Pubitemid 32549857)
20. L. Perrin, J. M. Pawlotsky, M. Bouvier-Alias, C. Sarrazin, S. Zeuzem, and G. Colucci, "Multicenter performance evaluation of a new TaqMan PCR assay for monitoring human immunodeficiency virus RNA load," J. Clin. Microbiol., vol. 44, no. 12, pp. 4371-4375, Dec. 2006. (Pubitemid 44937066)