메뉴 건너뛰기




Volumn 27, Issue 8, 2012, Pages 947-957

Nicotine as a potential neuroprotective agent for Parkinson's disease

Author keywords

Neuroprotection; Nicotine; Nicotinic; Nigrostriatal damage; Parkinson's disease

Indexed keywords

ACETYLCYSTEINE; BEE VENOM; BUNGAROTOXIN RECEPTOR; CHOLINERGIC RECEPTOR; CREATINE; DEFERIPRONE; ERYTHROPOIETIN; EXENDIN 4; FOLIC ACID; GANGLIOSIDE GM1; GLUTATHIONE; GPI 1485; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOMODULATING AGENT; INOSINE; ISRADIPINE; MINOCYCLINE; MITOQUIDONE; NICOTINE; NICOTINE PATCH; NICOTINIC RECEPTOR ALPHA4BETA2; PIOGLITAZONE; PLACEBO; POLYPHENOL; PRELADENANT; RASAGILINE; SAFINAMIDE; UBIDECARENONE; UBIQUINONE;

EID: 84864005036     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25028     Document Type: Review
Times cited : (188)

References (130)
  • 1
    • 79957606041 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Schapira AH, Jenner P. Etiology and pathogenesis of Parkinson's disease. Mov Disord. 2011; 26: 1049-1055.
    • (2011) Mov Disord. , vol.26 , pp. 1049-1055
    • Schapira, A.H.1    Jenner, P.2
  • 3
    • 79957603259 scopus 로고    scopus 로고
    • Milestones in Parkinson's disease therapeutics
    • Rascol O, Lozano A, Stern M, Poewe W. Milestones in Parkinson's disease therapeutics. Mov Disord. 2011; 26: 1072-1082.
    • (2011) Mov Disord. , vol.26 , pp. 1072-1082
    • Rascol, O.1    Lozano, A.2    Stern, M.3    Poewe, W.4
  • 4
    • 58149131277 scopus 로고    scopus 로고
    • Neurobiology and treatment of Parkinson's disease
    • Schapira AH. Neurobiology and treatment of Parkinson's disease. Trends Pharmacol Sci. 2009; 30: 41-47.
    • (2009) Trends Pharmacol Sci. , vol.30 , pp. 41-47
    • Schapira, A.H.1
  • 5
    • 79957606507 scopus 로고    scopus 로고
    • Milestones in research on the pathophysiology of Parkinson's disease
    • Wichmann T, DeLong MR, Guridi J, Obeso JA. Milestones in research on the pathophysiology of Parkinson's disease. Mov Disord. 2011; 26: 1032-1041.
    • (2011) Mov Disord. , vol.26 , pp. 1032-1041
    • Wichmann, T.1    DeLong, M.R.2    Guridi, J.3    Obeso, J.A.4
  • 6
    • 79957586330 scopus 로고    scopus 로고
    • Milestones in Parkinson's disease-clinical and pathologic features
    • Halliday G, Lees A, Stern M. Milestones in Parkinson's disease-clinical and pathologic features. Mov Disord. 2011; 26: 1015-1021.
    • (2011) Mov Disord. , vol.26 , pp. 1015-1021
    • Halliday, G.1    Lees, A.2    Stern, M.3
  • 7
    • 77953229747 scopus 로고    scopus 로고
    • Missing pieces in the Parkinson's disease puzzle
    • Obeso JA, Rodriguez-Oroz MC, Goetz CG, et al. Missing pieces in the Parkinson's disease puzzle. Nat Med, 2010; 16: 653-661.
    • (2010) Nat Med , vol.16 , pp. 653-661
    • Obeso, J.A.1    Rodriguez-Oroz, M.C.2    Goetz, C.G.3
  • 9
    • 77957570725 scopus 로고    scopus 로고
    • Environmental and familial risk factors of Parkinsons disease: case-control study
    • Sanyal J, Chakraborty DP, Sarkar B, et al. Environmental and familial risk factors of Parkinsons disease: case-control study. Can J Neurol. Sci. 2010; 37: 637-642.
    • (2010) Can J Neurol. Sci. , vol.37 , pp. 637-642
    • Sanyal, J.1    Chakraborty, D.P.2    Sarkar, B.3
  • 10
    • 77953468252 scopus 로고    scopus 로고
    • Advances in environmental epidemiology
    • Tanner CM. Advances in environmental epidemiology. Mov Disord. 2010; 25( Suppl 1): S58-S62.
    • (2010) Mov Disord. , vol.25 , Issue.SUPPL. 1
    • Tanner, C.M.1
  • 11
    • 77953367806 scopus 로고    scopus 로고
    • Parkinson's disease: 10 years of progress, 1997-2007
    • Fahn S. Parkinson's disease: 10 years of progress, 1997-2007. Mov Disord. 2010; 25( Suppl 1): S2-S14.
    • (2010) Mov Disord. , vol.25 , Issue.SUPPL. 1
    • Fahn, S.1
  • 12
    • 79959728747 scopus 로고    scopus 로고
    • Epidemiology and etiology of Parkinson's disease: a review of the evidence
    • Wirdefeldt K, Adami HO, Cole P, Trichopoulos D, Mandel J. Epidemiology and etiology of Parkinson's disease: a review of the evidence. Eur J Epidemiol. 2011; 26( Suppl 1): S1-S58.
    • (2011) Eur J Epidemiol. , vol.26 , Issue.SUPPL. 1
    • Wirdefeldt, K.1    Adami, H.O.2    Cole, P.3    Trichopoulos, D.4    Mandel, J.5
  • 13
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • Dawson TM, Ko HS, Dawson VL. Genetic animal models of Parkinson's disease. Neuron. 2010; 66: 646-661.
    • (2010) Neuron. , vol.66 , pp. 646-661
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3
  • 14
    • 76949097385 scopus 로고    scopus 로고
    • Gene therapy in Parkinson's disease: rationale and current status
    • Feng LR, Maguire-Zeiss KA. Gene therapy in Parkinson's disease: rationale and current status. CNS Drugs. 2010; 24: 177-192.
    • (2010) CNS Drugs. , vol.24 , pp. 177-192
    • Feng, L.R.1    Maguire-Zeiss, K.A.2
  • 15
    • 79957620836 scopus 로고    scopus 로고
    • Parkinson's disease, proteins, and prions: milestones
    • Olanow CW, McNaught K. Parkinson's disease, proteins, and prions: milestones. Mov Disord. 2011; 26: 1056-1071.
    • (2011) Mov Disord. , vol.26 , pp. 1056-1071
    • Olanow, C.W.1    McNaught, K.2
  • 16
    • 72649106419 scopus 로고    scopus 로고
    • Rodent models of treatment-induced motor complications in Parkinson's disease
    • Cenci MA, Ohlin KE. Rodent models of treatment-induced motor complications in Parkinson's disease. Parkinsonism Relat Disord. 2009; 15( Suppl 4): S13-S17.
    • (2009) Parkinsonism Relat Disord. , vol.15 , Issue.SUPPL. 4
    • Cenci, M.A.1    Ohlin, K.E.2
  • 17
    • 58349099832 scopus 로고    scopus 로고
    • Functional models of Parkinson's disease: A valuable tool in the development of novel therapies
    • Jenner P. Functional models of Parkinson's disease: A valuable tool in the development of novel therapies. Ann Neurol. 2009; 64: S16-S29.
    • (2009) Ann Neurol. , vol.64
    • Jenner, P.1
  • 18
    • 81255210997 scopus 로고    scopus 로고
    • Modelling of Parkinson's disease in mice
    • Chesselet MF, Richter F. Modelling of Parkinson's disease in mice. Lancet Neurol. 2011; 10: 1108-1118.
    • (2011) Lancet Neurol. , vol.10 , pp. 1108-1118
    • Chesselet, M.F.1    Richter, F.2
  • 19
    • 77957245642 scopus 로고    scopus 로고
    • Genetic mouse models of Parkinson's disease. The state of the art
    • Magen I, Chesselet MF. Genetic mouse models of Parkinson's disease. The state of the art. Prog Brain Res. 2010; 184: 53-87.
    • (2010) Prog Brain Res. , vol.184 , pp. 53-87
    • Magen, I.1    Chesselet, M.F.2
  • 20
    • 79957608284 scopus 로고    scopus 로고
    • A tale on animal models of Parkinson's disease
    • Bezard E, Przedborski S. A tale on animal models of Parkinson's disease. Mov Disord. 2011; 26: 993-1002.
    • (2011) Mov Disord. , vol.26 , pp. 993-1002
    • Bezard, E.1    Przedborski, S.2
  • 21
    • 77649284470 scopus 로고    scopus 로고
    • Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice
    • Pan-Montojo F, Anichtchik O, Dening Y, et al. Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. PLoS One. 2010; 5: e8762.
    • (2010) PLoS One. , vol.5
    • Pan-Montojo, F.1    Anichtchik, O.2    Dening, Y.3
  • 22
    • 41049099938 scopus 로고    scopus 로고
    • Progress in neuroprotection in Parkinson's disease
    • Schapira AH. Progress in neuroprotection in Parkinson's disease. Eur J Neurol. 2008; 15( Suppl 1): 5-13.
    • (2008) Eur J Neurol. , vol.15 , Issue.SUPPL. 1 , pp. 5-13
    • Schapira, A.H.1
  • 23
    • 65549091910 scopus 로고    scopus 로고
    • Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases
    • Yang L, Calingasan NY, Wille EJ, et al. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. J Neurochem. 2009; 109: 1427-1439.
    • (2009) J Neurochem. , vol.109 , pp. 1427-1439
    • Yang, L.1    Calingasan, N.Y.2    Wille, E.J.3
  • 24
    • 34248550990 scopus 로고    scopus 로고
    • Neuroprotection for Parkinson's disease
    • LeWitt PA. Neuroprotection for Parkinson's disease. J Neural Transm Suppl. 2006: 113-122.
    • (2006) J Neural Transm Suppl. , pp. 113-122
    • LeWitt, P.A.1
  • 25
    • 33846418007 scopus 로고    scopus 로고
    • Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease
    • Zeevalk GD, Manzino L, Sonsalla PK, Bernard LP. Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. Exp Neurol. 2007; 203: 512-520.
    • (2007) Exp Neurol. , vol.203 , pp. 512-520
    • Zeevalk, G.D.1    Manzino, L.2    Sonsalla, P.K.3    Bernard, L.P.4
  • 26
    • 79958167912 scopus 로고    scopus 로고
    • Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo
    • Reglodi D, Kiss P, Lubics A, Tamas A. Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo. Curr Pharm Des. 2011; 17: 962-972.
    • (2011) Curr Pharm Des. , vol.17 , pp. 962-972
    • Reglodi, D.1    Kiss, P.2    Lubics, A.3    Tamas, A.4
  • 27
    • 37549058856 scopus 로고    scopus 로고
    • Encapsulated cell biodelivery of GDNF: a novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease?
    • Lindvall O, Wahlberg LU. Encapsulated cell biodelivery of GDNF: a novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease? Exp Neurol. 2008; 209: 82-88.
    • (2008) Exp Neurol. , vol.209 , pp. 82-88
    • Lindvall, O.1    Wahlberg, L.U.2
  • 29
    • 75949127404 scopus 로고    scopus 로고
    • Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders
    • von Bernhardi R, Tichauer JE, Eugenin J. Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders. J Neurochem. 2010; 112: 1099-1114.
    • (2010) J Neurochem. , vol.112 , pp. 1099-1114
    • von Bernhardi, R.1    Tichauer, J.E.2    Eugenin, J.3
  • 30
    • 73149116008 scopus 로고    scopus 로고
    • T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?
    • Appel SH, Beers DR, Henkel JS. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening? Trends Immunol. 2010; 31: 7-17.
    • (2010) Trends Immunol. , vol.31 , pp. 7-17
    • Appel, S.H.1    Beers, D.R.2    Henkel, J.S.3
  • 31
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: a target for neuroprotection?
    • Hirsch EC, Hunot S. Neuroinflammation in Parkinson's disease: a target for neuroprotection? Lancet Neurol. 2009; 8: 382-397.
    • (2009) Lancet Neurol. , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 32
    • 34347359673 scopus 로고    scopus 로고
    • 'Rejuvenation' protects neurons in mouse models of Parkinson's disease
    • Chan CS, Guzman JN, Ilijic E, et al. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature. 2007; 447: 1081-1086.
    • (2007) Nature. , vol.447 , pp. 1081-1086
    • Chan, C.S.1    Guzman, J.N.2    Ilijic, E.3
  • 33
    • 77958525474 scopus 로고    scopus 로고
    • Voluptuary habits and clinical subtypes of Parkinson's disease: the FRAGAMP case-control study
    • Nicoletti A, Pugliese P, Nicoletti G, et al. Voluptuary habits and clinical subtypes of Parkinson's disease: the FRAGAMP case-control study. Mov Disord. 2010; 25: 2387-2394.
    • (2010) Mov Disord. , vol.25 , pp. 2387-2394
    • Nicoletti, A.1    Pugliese, P.2    Nicoletti, G.3
  • 34
  • 37
    • 45149122797 scopus 로고    scopus 로고
    • Serum urate as a predictor of clinical and radiographic progression in Parkinson disease
    • Schwarzschild MA, Schwid SR, Marek K, et al. Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Arch Neurol. 2008; 65: 716-723.
    • (2008) Arch Neurol. , vol.65 , pp. 716-723
    • Schwarzschild, M.A.1    Schwid, S.R.2    Marek, K.3
  • 39
    • 79952918806 scopus 로고    scopus 로고
    • Novel therapy in Parkinson's disease: adenosine A(2A) receptor antagonists
    • Szabo N, Kincses ZT, Vecsei L. Novel therapy in Parkinson's disease: adenosine A(2A) receptor antagonists. Expert Opin Drug Metab Toxicol. 2011; 7: 441-455.
    • (2011) Expert Opin Drug Metab Toxicol. , vol.7 , pp. 441-455
    • Szabo, N.1    Kincses, Z.T.2    Vecsei, L.3
  • 40
    • 77956209909 scopus 로고    scopus 로고
    • Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms
    • Prediger RD. Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms. J Alzheimers Dis. 2010; 20( Suppl 1): S205-S220.
    • (2010) J Alzheimers Dis. , vol.20 , Issue.SUPPL. 1
    • Prediger, R.D.1
  • 41
    • 77950505354 scopus 로고    scopus 로고
    • Smoking duration, intensity, and risk of Parkinson disease
    • Chen H, Huang X, Guo X, et al. Smoking duration, intensity, and risk of Parkinson disease. Neurology. 2010; 74: 878-884.
    • (2010) Neurology. , vol.74 , pp. 878-884
    • Chen, H.1    Huang, X.2    Guo, X.3
  • 42
    • 0029078869 scopus 로고
    • Cigarette smoking and protection from Parkinson's disease: false association or etiologic clue?
    • Morens DM, Grandinetti A, Reed D, White LR, Ross GW. Cigarette smoking and protection from Parkinson's disease: false association or etiologic clue? Neurology. 1995; 45: 1041-1051.
    • (1995) Neurology. , vol.45 , pp. 1041-1051
    • Morens, D.M.1    Grandinetti, A.2    Reed, D.3    White, L.R.4    Ross, G.W.5
  • 43
    • 34447255185 scopus 로고    scopus 로고
    • Pooled analysis of tobacco use and risk of Parkinson disease
    • Ritz B, Ascherio A, Checkoway H, et al. Pooled analysis of tobacco use and risk of Parkinson disease. Arch Neurol. 2007; 64: 990-997.
    • (2007) Arch Neurol. , vol.64 , pp. 990-997
    • Ritz, B.1    Ascherio, A.2    Checkoway, H.3
  • 44
    • 33947546011 scopus 로고    scopus 로고
    • Temporal relationship between cigarette smoking and risk of Parkinson disease
    • Thacker EL, O'Reilly EJ, Weisskopf MG, et al. Temporal relationship between cigarette smoking and risk of Parkinson disease. Neurology. 2007; 68: 764-768.
    • (2007) Neurology. , vol.68 , pp. 764-768
    • Thacker, E.L.1    O'Reilly, E.J.2    Weisskopf, M.G.3
  • 45
    • 27844560214 scopus 로고    scopus 로고
    • Smokeless tobacco use and the risk of Parkinson's disease mortality
    • O'Reilly EJ, McCullough ML, Chao A, et al. Smokeless tobacco use and the risk of Parkinson's disease mortality. Mov Disord. 2005: 1383-1384.
    • (2005) Mov Disord. , pp. 1383-1384
    • O'Reilly, E.J.1    McCullough, M.L.2    Chao, A.3
  • 47
    • 0037176809 scopus 로고    scopus 로고
    • Smoking and Parkinson's disease in twins
    • Tanner CM, Goldman SM, Aston DA, et al. Smoking and Parkinson's disease in twins. Neurology. 2002; 58: 581-588.
    • (2002) Neurology. , vol.58 , pp. 581-588
    • Tanner, C.M.1    Goldman, S.M.2    Aston, D.A.3
  • 48
    • 0035690443 scopus 로고    scopus 로고
    • Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease
    • Ross GW, Petrovitch H. Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease. Drugs Aging. 2001; 18: 797-806.
    • (2001) Drugs Aging. , vol.18 , pp. 797-806
    • Ross, G.W.1    Petrovitch, H.2
  • 50
  • 51
    • 0030065436 scopus 로고    scopus 로고
    • Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious
    • Baron JA. Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious. Br Med Bull. 1996; 52: 58-73.
    • (1996) Br Med Bull. , vol.52 , pp. 58-73
    • Baron, J.A.1
  • 52
    • 0347415715 scopus 로고    scopus 로고
    • Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection; are there links?
    • Castagnoli K, Murugesan T. Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection; are there links? Neurotoxicology. 2004; 25: 279-291.
    • (2004) Neurotoxicology. , vol.25 , pp. 279-291
    • Castagnoli, K.1    Murugesan, T.2
  • 53
    • 0037713665 scopus 로고    scopus 로고
    • Inhibition of human MAO-A and MAO-B by a compound isolated from flue-cured tobacco leaves and its neuroprotective properties in the MPTP mouse model of neurodegeneration
    • Castagnoli K, Petzer JB, Steyn SJ, van der Schyf CJ, Castagnoli NJr., Inhibition of human MAO-A and MAO-B by a compound isolated from flue-cured tobacco leaves and its neuroprotective properties in the MPTP mouse model of neurodegeneration. Inflammopharmacology. 2003; 11: 183-188.
    • (2003) Inflammopharmacology. , vol.11 , pp. 183-188
    • Castagnoli, K.1    Petzer, J.B.2    Steyn, S.J.3    van der Schyf, C.J.4    Castagnoli Jr., N.5
  • 55
    • 41249090400 scopus 로고    scopus 로고
    • Protection against Parkinson's disease progression: clinical experience
    • LeWitt PA, Taylor DC. Protection against Parkinson's disease progression: clinical experience. Neurotherapeutics. 2008; 5: 210-225.
    • (2008) Neurotherapeutics. , vol.5 , pp. 210-225
    • LeWitt, P.A.1    Taylor, D.C.2
  • 56
    • 77956092544 scopus 로고    scopus 로고
    • Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity
    • Weinreb O, Amit T, Bar-Am O, Youdim MB. Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity. Prog Neurobiol. 2010; 92: 330-344.
    • (2010) Prog Neurobiol. , vol.92 , pp. 330-344
    • Weinreb, O.1    Amit, T.2    Bar-Am, O.3    Youdim, M.B.4
  • 57
    • 79954706259 scopus 로고    scopus 로고
    • A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes
    • Rascol O, Fitzer-Attas CJ, Hauser R, et al. A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes. Lancet Neurol. 2011; 10: 415-423.
    • (2011) Lancet Neurol. , vol.10 , pp. 415-423
    • Rascol, O.1    Fitzer-Attas, C.J.2    Hauser, R.3
  • 58
    • 0036891570 scopus 로고    scopus 로고
    • Cholinergic interneuron characteristics and nicotinic properties in the striatum
    • Zhou FM, Wilson CJ, Dani JA. Cholinergic interneuron characteristics and nicotinic properties in the striatum. J Neurobiol. 2002; 53: 590-605.
    • (2002) J Neurobiol. , vol.53 , pp. 590-605
    • Zhou, F.M.1    Wilson, C.J.2    Dani, J.A.3
  • 59
    • 34548692998 scopus 로고    scopus 로고
    • The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum
    • Grady SR, Salminen O, Laverty DC, et al. The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum. Biochem Pharmacol. 2007; 74: 1235-1246.
    • (2007) Biochem Pharmacol. , vol.74 , pp. 1235-1246
    • Grady, S.R.1    Salminen, O.2    Laverty, D.C.3
  • 60
    • 80053909727 scopus 로고    scopus 로고
    • * Nicotinic acetylcholine receptors as drug targets for Parkinson's disease
    • * Nicotinic acetylcholine receptors as drug targets for Parkinson's disease. Pharmacol Rev. 2011; 63: 938-966.
    • (2011) Pharmacol Rev. , vol.63 , pp. 938-966
    • Quik, M.1    Wonnacott, S.2
  • 62
    • 38449098712 scopus 로고    scopus 로고
    • Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
    • Picciotto MR, Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Front Biosci. 2008; 13: 492-504.
    • (2008) Front Biosci. , vol.13 , pp. 492-504
    • Picciotto, M.R.1    Zoli, M.2
  • 64
    • 0035847204 scopus 로고    scopus 로고
    • Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra
    • Costa G, Abin-Carriquiry JA, Dajas F. Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra. Brain Res. 2001; 888: 336-342.
    • (2001) Brain Res. , vol.888 , pp. 336-342
    • Costa, G.1    Abin-Carriquiry, J.A.2    Dajas, F.3
  • 65
    • 0035544933 scopus 로고    scopus 로고
    • Involvement of nicotinic acetylcholine receptors in the protection of dopamine terminals in experimental parkinsonism
    • Dajas F, Costa G, Abin-Carriquiry JA, McGregor R, Urbanavicius J. Involvement of nicotinic acetylcholine receptors in the protection of dopamine terminals in experimental parkinsonism. Funct Neurol. 2001; 16( Suppl 4): 113-123.
    • (2001) Funct Neurol. , vol.16 , Issue.SUPPL. 4 , pp. 113-123
    • Dajas, F.1    Costa, G.2    Abin-Carriquiry, J.A.3    McGregor, R.4    Urbanavicius, J.5
  • 66
    • 64349110062 scopus 로고    scopus 로고
    • Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys
    • Huang LZ, Parameswaran N, Bordia T, Michael McIntosh J, Quik M. Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys. J Neurochem. 2009; 109: 826-837.
    • (2009) J Neurochem. , vol.109 , pp. 826-837
    • Huang, L.Z.1    Parameswaran, N.2    Bordia, T.3    Michael McIntosh, J.4    Quik, M.5
  • 67
    • 0035793423 scopus 로고    scopus 로고
    • Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice
    • Parain K, Marchand V, Dumery B, Hirsch E. Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice. Brain Res. 2001; 890: 347-350.
    • (2001) Brain Res. , vol.890 , pp. 347-350
    • Parain, K.1    Marchand, V.2    Dumery, B.3    Hirsch, E.4
  • 68
    • 0035036071 scopus 로고    scopus 로고
    • Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in alpha4 nicotinic receptor subunit knockout mice
    • Ryan RE, Ross SA, Drago J, Loiacono RE. Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in alpha4 nicotinic receptor subunit knockout mice. Br J Pharmacol. 2001; 132: 1650-1656.
    • (2001) Br J Pharmacol. , vol.132 , pp. 1650-1656
    • Ryan, R.E.1    Ross, S.A.2    Drago, J.3    Loiacono, R.E.4
  • 69
    • 80051701494 scopus 로고    scopus 로고
    • Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+
    • Toulorge D, Guerreiro S, Hild A, Maskos U, Hirsch EC, Michel PP. Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+. FASEB J. 2011; 25: 2563-2573.
    • (2011) FASEB J. , vol.25 , pp. 2563-2573
    • Toulorge, D.1    Guerreiro, S.2    Hild, A.3    Maskos, U.4    Hirsch, E.C.5    Michel, P.P.6
  • 70
    • 33747360178 scopus 로고    scopus 로고
    • Nicotine, but neither the alpha4beta2 ligand RJR2403 nor an alpha7 nAChR subtype selective agonist, protects against a partial 6-hydroxydopamine lesion of the rat median forebrain bundle
    • Visanji NP, O'Neill M J, Duty S. Nicotine, but neither the alpha4beta2 ligand RJR2403 nor an alpha7 nAChR subtype selective agonist, protects against a partial 6-hydroxydopamine lesion of the rat median forebrain bundle. Neuropharmacology. 2006; 51: 506-516.
    • (2006) Neuropharmacology. , vol.51 , pp. 506-516
    • Visanji, N.P.1    O'Neill M, J.2    Duty, S.3
  • 71
    • 33646823452 scopus 로고    scopus 로고
    • Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates
    • Quik M, Chen L, Parameswaran N, Xie X, Langston JW, McCallum SE. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned primates. J. Neurosci 2006; 26: 4681-4689.
    • (2006) J. Neurosci , vol.26 , pp. 4681-4689
    • Quik, M.1    Chen, L.2    Parameswaran, N.3    Xie, X.4    Langston, J.W.5    McCallum, S.E.6
  • 72
    • 33748159130 scopus 로고    scopus 로고
    • Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates
    • Quik M, Parameswaran N, McCallum SE, et al. Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. J Neurochem. 2006; 98: 1866-1875.
    • (2006) J Neurochem. , vol.98 , pp. 1866-1875
    • Quik, M.1    Parameswaran, N.2    McCallum, S.E.3
  • 73
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: from structure to function
    • Albuquerque EX, Pereira EF, Alkondon M, Rogers SW. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev. 2009; 89: 73-120.
    • (2009) Physiol Rev. , vol.89 , pp. 73-120
    • Albuquerque, E.X.1    Pereira, E.F.2    Alkondon, M.3    Rogers, S.W.4
  • 74
    • 58049091080 scopus 로고    scopus 로고
    • Diversity of vertebrate nicotinic acetylcholine receptors
    • Millar NS, Gotti C. Diversity of vertebrate nicotinic acetylcholine receptors. Neuropharmacology. 2009; 56: 237-246.
    • (2009) Neuropharmacology. , vol.56 , pp. 237-246
    • Millar, N.S.1    Gotti, C.2
  • 76
    • 77951006621 scopus 로고    scopus 로고
    • * receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement
    • * receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement. J. Neurosci 2010; 30: 5311-5325.
    • (2010) J. Neurosci , vol.30 , pp. 5311-5325
    • Gotti, C.1    Guiducci, S.2    Tedesco, V.3
  • 77
    • 43249103338 scopus 로고    scopus 로고
    • Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: Potential targets for the development of new therapeutic agents
    • Ward RJ, Lallemand F, de Witte P, Dexter DT. Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: Potential targets for the development of new therapeutic agents. Prog Neurobiol. 2008; 85: 135-147.
    • (2008) Prog Neurobiol. , vol.85 , pp. 135-147
    • Ward, R.J.1    Lallemand, F.2    de Witte, P.3    Dexter, D.T.4
  • 78
    • 0036777468 scopus 로고    scopus 로고
    • Nicotine and nicotinic receptors; relevance to Parkinson's disease
    • Quik M, Kulak JM. Nicotine and nicotinic receptors; relevance to Parkinson's disease. Neurotoxicology. 2002; 23: 581-594.
    • (2002) Neurotoxicology. , vol.23 , pp. 581-594
    • Quik, M.1    Kulak, J.M.2
  • 79
    • 63149095488 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models
    • Shimohama S. Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models. Biol Pharm Bull. 2009; 32: 332-336.
    • (2009) Biol Pharm Bull. , vol.32 , pp. 332-336
    • Shimohama, S.1
  • 80
    • 0036392590 scopus 로고    scopus 로고
    • Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages)
    • Braak H, Del Tredici K, Bratzke H, Hamm-Clement J, Sandmann-Keil D, Rub U. Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages). J Neurol. 2002; 249( Suppl 3): III/1-5.
    • (2002) J Neurol. , vol.249 , Issue.SUPPL. 3
    • Braak, H.1    Del Tredici, K.2    Bratzke, H.3    Hamm-Clement, J.4    Sandmann-Keil, D.5    Rub, U.6
  • 82
    • 33750377224 scopus 로고    scopus 로고
    • Pathology associated with sporadic Parkinson's disease-where does it end?
    • Braak H, Muller CM, Rub U, et al. Pathology associated with sporadic Parkinson's disease-where does it end? J Neural Transm Suppl. 2006: 89-97.
    • (2006) J Neural Transm Suppl. , pp. 89-97
    • Braak, H.1    Muller, C.M.2    Rub, U.3
  • 83
    • 78651317992 scopus 로고    scopus 로고
    • alpha4beta2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling
    • Hosur V, Loring RH. alpha4beta2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling. Mol Pharmacol. 2011; 79: 167-174.
    • (2011) Mol Pharmacol. , vol.79 , pp. 167-174
    • Hosur, V.1    Loring, R.H.2
  • 84
    • 2542486433 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and the regulation of neuronal signalling
    • Dajas-Bailador F, Wonnacott S. Nicotinic acetylcholine receptors and the regulation of neuronal signalling. Trends Pharmacol Sci. 2004; 25: 317-324.
    • (2004) Trends Pharmacol Sci. , vol.25 , pp. 317-324
    • Dajas-Bailador, F.1    Wonnacott, S.2
  • 85
    • 33845894963 scopus 로고    scopus 로고
    • Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms
    • Mudo G, Belluardo N, Fuxe K. Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms. J Neural Transm. 2007; 114: 135-147.
    • (2007) J Neural Transm. , vol.114 , pp. 135-147
    • Mudo, G.1    Belluardo, N.2    Fuxe, K.3
  • 86
    • 4344698859 scopus 로고    scopus 로고
    • Smoking, nicotine and Parkinson's disease
    • Quik M. Smoking, nicotine and Parkinson's disease. Trends Neurosci 2004; 27: 561-568.
    • (2004) Trends Neurosci , vol.27 , pp. 561-568
    • Quik, M.1
  • 87
    • 79955671904 scopus 로고    scopus 로고
    • Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases
    • Kawamata J, Shimohama S. Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases. J Alzheimers Dis. 2011; 24( Suppl 2): 95-109.
    • (2011) J Alzheimers Dis. , vol.24 , Issue.SUPPL. 2 , pp. 95-109
    • Kawamata, J.1    Shimohama, S.2
  • 88
    • 0033846277 scopus 로고    scopus 로고
    • Central nicotinic receptors, neurotrophic factors and neuroprotection
    • Belluardo N, Mudo G, Blum M, Fuxe K. Central nicotinic receptors, neurotrophic factors and neuroprotection. Behav Brain Res. 2000; 113: 21-34.
    • (2000) Behav Brain Res. , vol.113 , pp. 21-34
    • Belluardo, N.1    Mudo, G.2    Blum, M.3    Fuxe, K.4
  • 89
    • 33751533916 scopus 로고    scopus 로고
    • BDNF up-regulates alpha7 nicotinic acetylcholine receptor levels on subpopulations of hippocampal interneurons
    • Massey KA, Zago WM, Berg DK. BDNF up-regulates alpha7 nicotinic acetylcholine receptor levels on subpopulations of hippocampal interneurons. Mol Cell Neurosci. 2006; 33: 381-388.
    • (2006) Mol Cell Neurosci. , vol.33 , pp. 381-388
    • Massey, K.A.1    Zago, W.M.2    Berg, D.K.3
  • 90
    • 2342493316 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and trkB signaling in parasympathetic neurons: relevance to regulating alpha7-containing nicotinic receptors and synaptic function
    • Zhou X, Nai Q, Chen M, Dittus JD, Howard MJ, Margiotta JF. Brain-derived neurotrophic factor and trkB signaling in parasympathetic neurons: relevance to regulating alpha7-containing nicotinic receptors and synaptic function. J. Neurosci 2004; 24: 4340-4350.
    • (2004) J. Neurosci , vol.24 , pp. 4340-4350
    • Zhou, X.1    Nai, Q.2    Chen, M.3    Dittus, J.D.4    Howard, M.J.5    Margiotta, J.F.6
  • 91
    • 77951913601 scopus 로고    scopus 로고
    • Nicotine increases the expression of neurotrophin receptor tyrosine kinase receptor A in basal forebrain cholinergic neurons
    • Formaggio E, Fazzini F, Dalfini AC, et al. Nicotine increases the expression of neurotrophin receptor tyrosine kinase receptor A in basal forebrain cholinergic neurons. Neuroscience. 2010; 166: 580-589.
    • (2010) Neuroscience. , vol.166 , pp. 580-589
    • Formaggio, E.1    Fazzini, F.2    Dalfini, A.C.3
  • 92
    • 34447115746 scopus 로고    scopus 로고
    • Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action
    • Park HJ, Lee PH, Ahn YW, et al. Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. Eur J Neurosci. 2007; 26: 79-89.
    • (2007) Eur J Neurosci. , vol.26 , pp. 79-89
    • Park, H.J.1    Lee, P.H.2    Ahn, Y.W.3
  • 94
    • 66149103723 scopus 로고    scopus 로고
    • Cholinergic control of inflammation
    • Rosas-Ballina M, Tracey KJ. Cholinergic control of inflammation. J Intern Med. 2009; 265: 663-679.
    • (2009) J Intern Med. , vol.265 , pp. 663-679
    • Rosas-Ballina, M.1    Tracey, K.J.2
  • 98
    • 0036639946 scopus 로고    scopus 로고
    • Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity: relevance for Parkinson's disease
    • Soto-Otero R, Mendez-Alvarez E, Hermida-Ameijeiras A, Lopez-Real AM, Labandeira-Garcia JL. Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity: relevance for Parkinson's disease. Biochem Pharmacol. 2002; 64: 125-135.
    • (2002) Biochem Pharmacol. , vol.64 , pp. 125-135
    • Soto-Otero, R.1    Mendez-Alvarez, E.2    Hermida-Ameijeiras, A.3    Lopez-Real, A.M.4    Labandeira-Garcia, J.L.5
  • 99
    • 25444469905 scopus 로고    scopus 로고
    • Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria
    • Xie YX, Bezard E, Zhao BL. Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria. J Biol Chem. 2005; 280: 32405-32412.
    • (2005) J Biol Chem. , vol.280 , pp. 32405-32412
    • Xie, Y.X.1    Bezard, E.2    Zhao, B.L.3
  • 100
    • 52649088408 scopus 로고    scopus 로고
    • Continuous and intermittent nicotine treatment reduces L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias in a rat model of Parkinson's disease
    • Bordia T, Campos C, Huang L, Quik M. Continuous and intermittent nicotine treatment reduces L-3, 4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias in a rat model of Parkinson's disease. J Pharmacol Exp Ther. 2008; 327: 239-247.
    • (2008) J Pharmacol Exp Ther. , vol.327 , pp. 239-247
    • Bordia, T.1    Campos, C.2    Huang, L.3    Quik, M.4
  • 101
    • 77952480048 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated reduction in L-dopa-induced dyskinesias may occur via desensitization
    • Bordia T, Campos C, McIntosh JM, Quik M. Nicotinic receptor-mediated reduction in L-dopa-induced dyskinesias may occur via desensitization. J Pharmacol Exp Ther. 2010; 333: 929-938.
    • (2010) J Pharmacol Exp Ther. , vol.333 , pp. 929-938
    • Bordia, T.1    Campos, C.2    McIntosh, J.M.3    Quik, M.4
  • 102
    • 80052157475 scopus 로고    scopus 로고
    • Nicotine reduces L-dopa-induced dyskinesias by acting at {beta}2 nicotinic receptors
    • Huang L, Grady SR, Quik M. Nicotine reduces L-dopa-induced dyskinesias by acting at {beta}2 nicotinic receptors. J Pharmacol Exp Ther. 2011; 338: 932-941.
    • (2011) J Pharmacol Exp Ther. , vol.338 , pp. 932-941
    • Huang, L.1    Grady, S.R.2    Quik, M.3
  • 103
    • 0031826455 scopus 로고    scopus 로고
    • Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys
    • Schneider JS, Pope-Coleman A, Van Velson M, Menzaghi F, Lloyd GK. Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys. Mov Disord. 1998; 13: 637-642.
    • (1998) Mov Disord. , vol.13 , pp. 637-642
    • Schneider, J.S.1    Pope-Coleman, A.2    Van Velson, M.3    Menzaghi, F.4    Lloyd, G.K.5
  • 104
    • 0032816456 scopus 로고    scopus 로고
    • Nicotine alone and in combination with l-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys
    • Domino EF, Ni L, Zhang H. Nicotine alone and in combination with l-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys. Exp Neurol. 1999; 158: 414-421.
    • (1999) Exp Neurol. , vol.158 , pp. 414-421
    • Domino, E.F.1    Ni, L.2    Zhang, H.3
  • 105
    • 0027283754 scopus 로고
    • Effects of smoking in patients with early-onset Parkinson's disease
    • Ishikawa A, Miyatake T. Effects of smoking in patients with early-onset Parkinson's disease. J Neurol. Sci. 1993; 117: 28-32.
    • (1993) J Neurol. Sci. , vol.117 , pp. 28-32
    • Ishikawa, A.1    Miyatake, T.2
  • 107
    • 0028811960 scopus 로고
    • The short-term effect of nicotine chewing gum in patients with Parkinson's disease
    • Clemens P, Baron JA, Coffey D, Reeves A. The short-term effect of nicotine chewing gum in patients with Parkinson's disease. Psychopharmacology (Berl). 1995; 117: 253-256.
    • (1995) Psychopharmacology (Berl). , vol.117 , pp. 253-256
    • Clemens, P.1    Baron, J.A.2    Coffey, D.3    Reeves, A.4
  • 108
    • 0345439999 scopus 로고    scopus 로고
    • Worsening of motor performance in patients with Parkinson's disease following transdermal nicotine administration
    • Ebersbach G, Stock M, Muller J, Wenning G, Wissel J, Poewe W. Worsening of motor performance in patients with Parkinson's disease following transdermal nicotine administration. Mov Disord. 1999; 14: 1011-1013.
    • (1999) Mov Disord. , vol.14 , pp. 1011-1013
    • Ebersbach, G.1    Stock, M.2    Muller, J.3    Wenning, G.4    Wissel, J.5    Poewe, W.6
  • 110
    • 0035949796 scopus 로고    scopus 로고
    • Transdermal nicotine in PD: a randomized, double-blind, placebo-controlled study
    • Vieregge A, Sieberer M, Jacobs H, Hagenah JM, Vieregge P. Transdermal nicotine in PD: a randomized, double-blind, placebo-controlled study. Neurology. 2001; 57: 1032-1035.
    • (2001) Neurology. , vol.57 , pp. 1032-1035
    • Vieregge, A.1    Sieberer, M.2    Jacobs, H.3    Hagenah, J.M.4    Vieregge, P.5
  • 111
    • 36248953114 scopus 로고    scopus 로고
    • Chronic high dose transdermal nicotine in Parkinson's disease: an open trial
    • Villafane G, Cesaro P, Rialland A, et al. Chronic high dose transdermal nicotine in Parkinson's disease: an open trial. Eur J Neurol. 2007; 14: 1313-1316.
    • (2007) Eur J Neurol. , vol.14 , pp. 1313-1316
    • Villafane, G.1    Cesaro, P.2    Rialland, A.3
  • 112
    • 33646184356 scopus 로고    scopus 로고
    • Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease
    • Shoulson I. Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease. Neurology. 2006; 66: 408-410.
    • (2006) Neurology. , vol.66 , pp. 408-410
    • Shoulson, I.1
  • 113
    • 0347995105 scopus 로고    scopus 로고
    • Lack of efficacy of a nicotine transdermal treatment on motor and cognitive deficits in Parkinson's disease
    • Lemay S, Chouinard S, Blanchet P, et al. Lack of efficacy of a nicotine transdermal treatment on motor and cognitive deficits in Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2004; 28: 31-39.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry. , vol.28 , pp. 31-39
    • Lemay, S.1    Chouinard, S.2    Blanchet, P.3
  • 114
    • 57049160379 scopus 로고    scopus 로고
    • Nicotine and Parkinson's disease: implications for therapy
    • Quik M, O'Leary K, Tanner CM. Nicotine and Parkinson's disease: implications for therapy. Mov Disord. 2008; 23: 1641-1652.
    • (2008) Mov Disord. , vol.23 , pp. 1641-1652
    • Quik, M.1    O'Leary, K.2    Tanner, C.M.3
  • 116
    • 77953688842 scopus 로고    scopus 로고
    • Nicotine addiction
    • Benowitz NL. Nicotine addiction. N Engl J Med. 2010; 362: 2295-2303.
    • (2010) N Engl J Med. , vol.362 , pp. 2295-2303
    • Benowitz, N.L.1
  • 117
    • 79959877467 scopus 로고    scopus 로고
    • Reward, addiction, withdrawal to nicotine
    • De Biasi M, Dani JA. Reward, addiction, withdrawal to nicotine. Annu Rev Neurosci. 2010; 34: 105-130.
    • (2010) Annu Rev Neurosci. , vol.34 , pp. 105-130
    • De Biasi, M.1    Dani, J.A.2
  • 118
    • 57649136428 scopus 로고    scopus 로고
    • Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse
    • Dwoskin LP, Bardo MT. Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse. Neuropsychopharmacology. 2009; 34: 244-246.
    • (2009) Neuropsychopharmacology. , vol.34 , pp. 244-246
    • Dwoskin, L.P.1    Bardo, M.T.2
  • 119
    • 80052024155 scopus 로고    scopus 로고
    • Mechanistic insights into nicotine withdrawal
    • Paolini M, De Biasi M. Mechanistic insights into nicotine withdrawal. Biochem Pharmacol. 2011; 82: 996-1007.
    • (2011) Biochem Pharmacol. , vol.82 , pp. 996-1007
    • Paolini, M.1    De Biasi, M.2
  • 120
    • 79953862800 scopus 로고    scopus 로고
    • Pharmacotherapy for smoking cessation: current advances and research topics
    • Raupach T, van Schayck CP. Pharmacotherapy for smoking cessation: current advances and research topics. CNS Drugs. 2011; 25: 371-382.
    • (2011) CNS Drugs. , vol.25 , pp. 371-382
    • Raupach, T.1    van Schayck, C.P.2
  • 121
    • 57049123693 scopus 로고    scopus 로고
    • The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?
    • Hawkes CH. The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it? Mov Disord. 2008; 23: 1799-1807.
    • (2008) Mov Disord. , vol.23 , pp. 1799-1807
    • Hawkes, C.H.1
  • 123
    • 77949534717 scopus 로고    scopus 로고
    • Allosteric receptors: from electric organ to cognition
    • Changeux JP. Allosteric receptors: from electric organ to cognition. Annu Rev Pharmacol Toxicol. 2010; 50: 1-38.
    • (2010) Annu Rev Pharmacol Toxicol. , vol.50 , pp. 1-38
    • Changeux, J.P.1
  • 124
    • 68349125570 scopus 로고    scopus 로고
    • nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms
    • Sarter M, Parikh V, Howe WM. nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms. Biochem Pharmacol. 2009; 78: 658-667.
    • (2009) Biochem Pharmacol. , vol.78 , pp. 658-667
    • Sarter, M.1    Parikh, V.2    Howe, W.M.3
  • 125
    • 68549126834 scopus 로고    scopus 로고
    • Nicotinic actions on neuronal networks for cognition: general principles and long-term consequences
    • Poorthuis RB, Goriounova NA, Couey JJ, Mansvelder HD. Nicotinic actions on neuronal networks for cognition: general principles and long-term consequences. Biochem Pharmacol. 2009; 78: 668-676.
    • (2009) Biochem Pharmacol. , vol.78 , pp. 668-676
    • Poorthuis, R.B.1    Goriounova, N.A.2    Couey, J.J.3    Mansvelder, H.D.4
  • 127
    • 63849213473 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection
    • Buckingham SD, Jones AK, Brown LA, Sattelle DB. Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. Pharmacol Rev. 2009; 61: 39-61.
    • (2009) Pharmacol Rev. , vol.61 , pp. 39-61
    • Buckingham, S.D.1    Jones, A.K.2    Brown, L.A.3    Sattelle, D.B.4
  • 128
    • 72949084363 scopus 로고    scopus 로고
    • Mecamylamine -a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders
    • Bacher I, Wu B, Shytle DR, George TP. Mecamylamine -a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opin Pharmacother. 2009; 10: 2709-2721.
    • (2009) Expert Opin Pharmacother. , vol.10 , pp. 2709-2721
    • Bacher, I.1    Wu, B.2    Shytle, D.R.3    George, T.P.4
  • 129
    • 78449298645 scopus 로고    scopus 로고
    • Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis
    • Mineur YS, Picciotto MR. Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis. Trends Pharmacol Sci. 2010; 31: 580-586.
    • (2010) Trends Pharmacol Sci. , vol.31 , pp. 580-586
    • Mineur, Y.S.1    Picciotto, M.R.2
  • 130
    • 77954186129 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature
    • Philip NS, Carpenter LL, Tyrka AR, Price LH. Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature. Psychopharmacology (Berl). 2010; 212: 1-12.
    • (2010) Psychopharmacology (Berl). , vol.212 , pp. 1-12
    • Philip, N.S.1    Carpenter, L.L.2    Tyrka, A.R.3    Price, L.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.