Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity: Relevance for Parkinson's disease

Biochemical Pharmacology

Volumn 64, Issue 1, 2002, Pages 125-135

  Soto Otero, Ramón ^a   Méndez Álvarez, Estefanía ^a   Hermida Ameijeiras, Álvaro ^a   López Real, Ana María ^b   Labandeira García, José Luis ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

( ) Cotinine; ( ) Nicotine; 6 Hydroxydopamine; Dopaminergic neurotoxicity; Oxidative stress; Parkinson's disease

Indexed keywords

ASCORBIC ACID; COTININE; HYDROXYL RADICAL; NICOTINE; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

ANIMAL MODEL; ARTICLE; AUTOOXIDATION; BRAIN MITOCHONDRION; CHEMICAL REACTION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; MALE; NEUROPROTECTION; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; REDUCTION;

ADRENERGIC AGENTS; ANALYSIS OF VARIANCE; ANIMALS; CORPUS STRIATUM; COTININE; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; FEMALE; MALE; NEUROTOXICITY SYNDROMES; NICOTINE; NICOTINIC AGONISTS; OXIDATIVE STRESS; OXIDOPAMINE; PARKINSONIAN DISORDERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036639946     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01070-5     Document Type: Article

References (61)

1. The brainstem lesion in parkinsonism
2. Parkinson's disease: Pathophysiology
3. Free radicals and mitochondrial function in Parkinson's disease
4. Brain iron pathways and their relevance to Parkinson's disease
5. The pivotal role of iron in NF-kappa B activation and nigrostriatal dopaminergic neurodegeneration. Prospects for neuroprotection in Parkinson's disease with iron chelators
6. A retrospective study of smoking in Parkinson's disease
7. Cigarette smoking and Parkinson's disease
8. Cigarette smoking and protection from Parkinson's disease: False association or etiologic clue?
9. Smoking and Parkinson's disease: A case-control study in Germany
10. Cigarette smoke and the incidence of Parkinson's in two prospective studies
11. Role of human cytochrome P4502A6 in C-oxidation of nicotine
12. Metabolites of nicotine in rat brain after peripheral nicotine administration: Cotinine, nornicotine and norcotinine
13. Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo
14. In vitro and in vivo studies investigating possible antioxidant actions of nicotine: Relevance to Parkinson's and Alzheimer's diseases
15. Free radical production in nicotine treated pancreatic tissue
16. Comparison of pure nicotine- and smokeless tobacco extract-induced toxicities and oxidative stress
17. Nicotine enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
18. Chronic continue infusion of (-)-nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not the 6-hydroxydopamine-lesioned rat
19. Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra
20. Interaction of 1,2,3,4-tetrahydroisoquinoline with some components of cigarette smoke: Potential implications for Parkinson's disease
21. Inhibition of brain monoamimo oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke
22. Studies on the interaction of 1,2,3,4-tetrahydro-β-carboline and cigarette smoke: A potential mechanism of neuroprotection for Parkinson's disease
23. Reduction of rat brain levels of the endogenous dopaminergic proneurotoxins 1,2,3,4-tetrahydroisoquinoline and 1,2,3,4-tetrahydro-β-carboline by cigarette smoke
24. Mass fragmentography of dopamine and 6-OH-dopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus
25. The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls
26. Endogenous toxins as potential etiologic agents in Parkinson's disease
27. Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease
28. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro
29. Intermediates in the aerobic autoxidation of 6-hydroxydopamine: Relative importance under different reaction conditions
30. Destruction of sympathetic nerve terminals by 6-hydroxydopamine: Protection by 1-phenyl-3-(2-thiazolyl)-2-thiourea, diethyldithiocarbamate, methimazole, cysteamine, ethanol and n-butanol
31. Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: Behavioral and biochemical evidence
32. The iron chelator desferrioxamine (desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons
33. Free radical-generated neurotoxicity of 6-hydroxydopamine
34. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: Potential implication in relation to the pathogenesis of Parkinson's disease
35. Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine
36. Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine
37. Time course of striatal changes induced by 6-hydroxydopamine lesion of the nigrostriatal pathway, as studied by combined evaluation of rotational behaviour and striatal Fos expression
38. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
39. Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine
40. Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: Similarities with cell loss in Parkinson's disease
41. The effects of derangement of cell membrane structure and inhibitors on transferrin and iron uptake by reticulocytes
42. Effect of nicotine on transferrin binding and iron uptake by cultured rat placenta
43. A new role for nicotine: Selective inhibition of thromboxane formation by direct interaction with thromboxane synthase in human promyelocytic leukaemia cells differentiating into macrophages
44. Effects of superoxide dismutase and catalase on catalysis of 6-hydroxydopamine and 6-aminodopamine autoxidation by iron and ascorbate
45. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
46. Terephthalic acid: A dosimeter for the detection of hydroxyl radicals in vitro
47. In vitro inhibition of catalase activity by cigarette smoke: Relevance for oxidative stress
48. Electrochemical assay
49. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
50. Mechanism of inhibitory effects of chelating drugs on lipid peroxidation in rat brain homogenates
51. Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions
52. Interaction between metals, ligands, and oxygen in the autoxidation of 6-hydroxydopamine: Mechanisms by which metal chelation enhances inhibition by superoxide dismutase
53. Oxygen toxicity, oxygen radicals, transition metals and disease
54. Reactive oxygen species and the central nervous system
55. Pathological evidence for oxidative stress in Parkinson's disease and related degenerative disorders
56. Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
57. Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease and X-ray microanalysis
58. Iron accumulation in the substantia nigra in rats visualized by ultrasound
59. Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in α4 nicotinic receptor subunit knockout mice
60. Acute intermitent nicotine treatment produces regional increases of basic fibroblast growth factor messenger RNA and protein in the tel- and diencephalon of the rat
61. Nicotine prevents experimental parkinsonism in rodents and induces striatal increase of neurotrophic factors