Altered regulation of CXCR4 expression during aging contributes to increased CXCL12-dependent chemotactic migration of CD4 + T cells

Aging Cell

Volumn 11, Issue 4, 2012, Pages 651-658

  Cané, Stefania ^a   Ponnappan, Subramaniam ^b   Ponnappan, Usha ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Aging; CXCR4; Human; Signal transduction; T cell; Ubiquitin pathway

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

AGING; ARTICLE; CD4+ T LYMPHOCYTE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; UBIQUITINATION;

ADULT; AGED; AGED, 80 AND OVER; AGING; CD4-POSITIVE T-LYMPHOCYTES; CHEMOKINE CXCL12; CHEMOTAXIS, LEUKOCYTE; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; RECEPTORS, CCR5; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; UBIQUITIN THIOLESTERASE; UBIQUITINATION; YOUNG ADULT;

RODENTIA;

EID: 84864001597     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2012.00830.x     Document Type: Article

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