T cell chemokine receptor expression in aging

Journal of Immunology

Volumn 170, Issue 2, 2003, Pages 895-904

  Mo, Ruran ^a   Chen, Jun ^a   Han, Yin ^a   Bueno Cannizares, Cecelia ^a   Misek, David E ^a   Lescure, Pascal A ^a   Hanash, Samir ^a   Yung, Raymond L ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; STROMAL CELL DERIVED FACTOR 1;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; CHEMOTAXIS; CONTROLLED STUDY; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC POLYMORPHISM; IMMUNE RESPONSE; MEMORY CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL;

EID: 0037438476     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.2.895     Document Type: Article

References (94)

1. Dworsky, R., A. Paganini-Hill, M. Arthur, and J. Parker. 1983. Immune responses of healthy humans 83-104 years of age. J. Natl. Cancer Inst. 71:265.
2. Fagiolo, U., A. Amadori, R. Biselli, R. Paganelli, R. Nisini, E. Cozzi, R. Zamarchi, and R. D'Amelio. 1993. Quantitative and qualitative analysis of anti-tetanus toxoid antibody response in the elderly: Humoral immune response enhancement by thymostimulin. Vaccine 11:1336.
3. Mastroeni, I., N. Vescia, M. G. Pompa, M. S. Cattaruzza, G. P. Marini, and G. M. Fara. 1994. Immune response of the elderly to rabies vaccines. Vaccine 12:518.
4. Schweickart, V. L., A. Epp, C. J. Raport, and P. W. Gray. 2000. CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines. J. Biol. Chem. 275:9550.
5. International Union of Immunological Societies/World Health Organization Sub-committee on chemokine nomenclature. 2001. Chemokine/chemokine receptor nomenclature. J. Leukocyte Biol. 70:465.
6. Ruth, J. H., J. B. Rottman, K. J. Katschke Jr., S. Qin, L. Wu, G. LaRosa, P. Ponath, R. M. Pope, and A. E. Koch. 2001. Selective lymphocyte chemokine receptor expression in the rheumatoid joint. Arthritis Rheum. 44:2750.
7. Matsui, T., T. Akahoshi, R. Namai, A. Hashimoto, Y. Kurihara, M. Rana, A. Nishimura, H. Endo, H. Kitasato, S. Kawai, et al. 2001. Selective recruitment of CCR6-expressing cells by increased production of MIP-3α in rheumatoid arthritis. Clin. Exp. Immunol. 125:155.
8. Shadidi, K. R., K. M. Thompson, J. E. Henriksen, J. B. Natvig, and T. Aarvak. 2002. Association of antigen specificity and migratory capacity of memory T cells in rheumatoid arthritis. Scand. J. Immunol. 55:274.
9. Feng Y., C. C. Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872.
10. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Ponath, L. Wu, C. R. Mackay, G. LaRosa, W. Newman, et al. 1996. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135.
11. Doranz, B. J., J. Rucker, Y. Yi, R. J. Smyth, M. Samson, S. C. Peiper, M. Parmentier, R. G. Collman, and R. W. Doms. 1996. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptor CKR-5, CKR-3 and CKR-2b as fusion cofactors. Cell 85:1149.
12. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667.
13. Simmons, G., D. Wilkinson, J. D. Reeves, M. T. Dittmar, S. Beddows, J. Webers, G. Carnegie, U. Desselberger, P. W. Gray, R. A. Weiss, and P. R. Clapham, 1996. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lest or CCR5 as coreceptors for viral entry. J. Virol. 70:8355.
14. Amara A., S. L. Gall, O. Schwartz, J. Salamero, M. Montes, P. Loetscher, M. Baggiolini. J. L. Virelizier, and F. Arenzana-Seisdedos. 1997. HIV coreceptor downregulation as antiviral principle: SDF-1a-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J. Exp. Med. 186:139.
15. Reynes J., P. Portales, M. Segondy, V. Baillat, P. Andre, O. Avinens, M. C. Picot, J. Clot, J. F. Eliaou, and P. Corbeau. 2001. CD4 T cell surface CCR5 density as a host factor in HiV-1 disease progression. AIDS 15:1627.
16. + T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1. J. Infect. Dis. 181:927.
17. Chiao, E. Y., K. M. Ries, and M. A. Sande. 1999. AIDS and the elderly. Clin. Infect. Dis. 28:740.
18. Yazici, Y., and S. A. Paget. 2000. Elderly-onset rheumatoid arthritis. Rheum. Dis. Clin. N. Am. 26:517.
19. Giordano, T. J., K. A. Shedden, D. R. Schwartz, R. Kuick, J. M. G. Taylor, N. Lee, D. E. Misek, J. K. Greenson, S. L. R. Kardia, D. G. Beer, et al. 2001. Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. Am. J. Pathol. 159:1231.
20. Sallusto, F., E. Kremmer, B. Palermo, A. Hoy, P. Ponath, S. Qin, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells. Eur. J. Immunol. 29:2037.
21. Miller, R. A. 1999. Aging and immune function. In Fundamental Immunology, 4th Ed. W. E. Paul, ed. Lippincott-Raven, Philadelphia, p. 947.
22. Yung, R. L. 2000. Changes in immune function with age. Rheum. Dis. Clin. N. Am 26:455.
23. Charles, P. C., K. S. Weber. B. Cipriani, and C. F. Brosnan. 1999. Cytokine, chemokine and chemokine receptor mRNA expression in different strains of normal mice: Implications for establishment of a Th1/Th2 bias. J. Neuroimmunol. 100:64.
24. Weindruch, R. 1996. The retardation of aging by caloric restriction: Studies in rodents and primates. Toxicol. Pathol. 24:742.
25. + lymphocytes in physically active adults. Eur. J. Immunol. 23:2704.
26. + T cell subsets in human peripheral blood. Mech. Ageing Dev. 63:57.
27. Daynes, R. A., B. A. Araneo, W. B. Ershler, C. Maloney, G. Z. Li, and S. Y. Ryu. 1993. Altered regulation of IL-6 production with normal aging: Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative. J. Immunol. 150:5219.
28. Himi, T., I. Yoshioka, and A. Katura. 1997. Influence of age on the production of interleukin-8-like chemokine (CRO/CINC-1) in rat nasal mucosa. Eur. Arch. Otorhinolaryngol. 254:101.
29. Mariani, E., L. Pulsatelli, A. Meneghetti, P. Dolzani, I. Mazzetti, S. Neri, G. Ravaglia, P. Forti, and A. Facchini. 2001. Different IL-8 production by T and NK lymphocytes in elderly subjects. Mech. Ageing Dev. 122:1383.
30. Pulsatelli, L., R. Melconi, I. Mazzetti, P. Dolzani, A. Meneghetti, S. Neri, T. Silvestri, G. Ravaglia, P. Forti, A. Facchini, and E. Mariani. 2000. Chemokine production by peripheral blood mononuclear cells in elderly subjects. Mech. Ageing Dev. 121:89.
31. Gerli, R., D. Monti, O. Bistoni, A. M. Mazzone, G. Peri, A. Cossarizza, M. Di Gioacchino, M. E. Cesarotti, A. Doni, A. Mantovani, et al. 2000. Chemokines, sTNF-Rs, and sCD30 serum levels in healthy aged people and centenarians. Mech. Ageing Dev. 121:37.
32. Felsien, L. K., J. T. McDonald, S. M. Gleason, N. E. Berman, and R. M. Klein. 2001. Increased chemokine gene expression during aging in the murine brain. Brain Res. 890:137.
33. Tarazona, R., O. DelaRosa, C. Alonso, B. Ostos, J. Espejo, J. Pena, and R. Salana. 2000. Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells. Mech. Aging Dev. 121:77.
34. + T cells from secondary lymphoid organs. Blood 97:850.
35. Unutmaz, D., W. Xiang, M. J. Sunshine, J. Campbell, E. Butcher, and D. R. Littman. 2000. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. J. Immunol. 165:3284.
36. Creson, J. R., A. A. Lin, D. F. Broad, M. R. Roberts, and S. J. Anderson. 1999, The mode and duration of anti-CD28 costimulation determine resistance to infection by macrophage-tropic strains of human immunodeficiency virus type 1 in vitro. J. Virol. 73:9337.
37. Peacock, J. W., and F. R. Jirik. 1999. TCR activation inhibits chemotaxis toward stromal cell-derived factor-1: Evidence for reciprocal regulation between CXCR4 and the TCR. J. Immunol. 162:215.
38. + T lymphocytes. J. Immunol. 168:65.
39. Riley, J. L., K. Schlienger, P. J. Blair, B. Carreno, N. Craighead, D. Kim, R. G. Carroll, and C. H. June, 2000. Modulation of susceptibility to HIV-1 infection by the cytotoxic T lymphocyte antigen 4 costimulatory molecule. J. Exp. Med. 191:1987.
40. Pahlavani, M. A. 2000. Caloric restriction and immunosenescence: A current perspective. Front. Biosci. 5:D580.
41. Miller, R. A., B. Jacobson, G. Weil, and E. R. Simons. 1987. Diminished calcium influx in lectin-stimulated T cells from old mice. J. Cell. Physiol. 138:175.
42. Proust, J. J., C. R. Filburn, S. A. Harrison, M. A. Buchholz, and A. A. Nordin. 1987. Age-related defect in signal transduction during lectin activation of murine T lymphocytes. J. Immunol. 139:1472.
43. Grossmann, A., L. Maggio-Price, J. C. Jinneman, and P. S. Rabinovitch. 1991. Aging-related deficiency in intracellular calcium response to anti-CD3 or concanavalin A in murine T-cell subsets. J. Gerontol. Biol. Sci. 45:B81.
44. Shi, J., and R. A. Miller. 1992. Differential tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice. J. Gerontol. Biol. Sci. 47:B147.
45. Saini, A., and Y. Sei. 1993. Age-related impairment of early and late events of signal transduction in mouse immune cells. Life Sci. 52:1759.
46. + T-cell subsets. Cell. Immunol. 132:17.
47. Vidan, M. T., B. Fernandez-Gutierrez, C. Hernandez-Garcia, J. A. Serra, J. M. Ribera, M. Perez-Blas, J. R. Regueiro, A. Banares, and J. A. Jover. 1999. Functional integrity of the CD28 co-stimulatory pathway in T lymphocytes from elderly subjects. Age Ageing 28:221.
48. Kirk, C. J., A. M. Freilich, and R. A. Miller. 1999. Age-related decline in activation of JNK by TCR- and CD28-mediated signals in murine T lymphocytes. Cell. Immunol. 197:75.
49. + T cells. J. Biomed. Sci. 7:317.
50. Shieh, B., Y. E. Liau, P. S. Hsieh, Y. P. Yan, S. T. Wang, and C. Li. 2000. Influence of nucleotide polymorphisms in the CCR2 gene and the CCR5 promoter on the expression of cell surface CCR5 and CXCR4. Int. Immunol. 12: 13211.
51. Rosati, M., A. Valentin, D. J. Patenaude, and G. N. Pavlakis. 2001. CCAAT-enhancer-binding protein β (C/EBP β) activates CCR5 promoter: Increased C/EBP β and CCR5 in T lymphocytes from HIV-1-infected individuals. J. Immunol. 167:1654.
52. LeClair, K. P., M. A. Blanar, and P. A. Sharp. 1992. The p50 subunit of NF-κB associates with the NF-IL-6 transcription factor. Proc. Natl. Acad. Sci. USA 89: 8145.
53. Yamamoto, K., H. Takeshima, K. Hamada, M. Nakao, T. Kino, T. Nishi, M. Kochi, J. Kuratsu, T. Yoshimura, and Y. Ushio, 1999. Cloning and functional characterization of the 5′-flanking region of the human monocyte chemoattractant protein-1 receptor (CCR2) gene: Essential role of 5′- untranslated region in tissue-specific expression. J. Biol. Chem. 274:4646.
54. Hopken, U. E., H. D. Foss, D. Meyer, M. Hinz, K. Leder, H. Stein, and M. Lipp. 2002. Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs. Blood 99:1109.
55. Huber, M. A., A. Denk, R. U. Peter, L. Weber, N. Kraut, and T. Wirth. 2002. The 2/IκBα/NF-κB pathway plays a key role in the regulation of CCR3 and eotaxin-1 in fibroblasts: A critical link to dermatitis in IκBα-deficient mice, J. Biol. Chem. 277:1268.
56. Yang, M., H. Sang, A. Rahman, D. Wu, A. B. Malik, and R. D. Ye. 2001. Gα16 couples chemoattractant receptors to NF-κB activation. J. Immunol. 166:6885.
57. Ganju, R. K., S. A. Brubaker, J. Meyer, P. Dutt, Y. Yang, S. Qin, W. Newman, and J. E. Groopman. 1998. The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J. Biol. Chem. 273:23169.
58. Whisler, R. L., M. Chen, L. Beiqing, and K. W. Carle. 1997. Impaired induction of c-fos/c-jun genes and of transcriptional regulatory proteins binding distinct c-fos/c-jun promoter elements in activated human T cells during aging. Cell. Immunol. 175:41.
59. Ginn-Pease, M. E., and R. L. Whisler, 1998. Redox signals and NF-κB activation in T cells. Free Radical Biol. Med. 25:346.
60. Scotet, E., S. Schroeder, and A. Lanzavecchia. 2001. Molecular regulation of C-C chemokine receptor 3 expression in human T helper 2 cells. Blood 98:2568.
61. Samson, M., P. Soularue, G. Vassart, and M. Parmentier. 1996. The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3. Genomics 36:522.
62. + T cells. J. Leukocyte Biol. 68:568.
63. Sallusto, F., D. Lenig, C. R. Mackay, and A. Lanzavecchia. 1998. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187:875.
64. Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401:708.
65. Gillette, R. W., and A. Fox. 1980. Changes with age in the homing properties and mitogen responses of lymphocytes from normal and leukemia-prone mice. Cell. Immunol. 51:32.
66. Gillette, R. W. 1976. Studies of the T-lymphocytes resident in the spleens of thymectomized, irradiated, bone marrow-reconstituted (TXB) mice. Cell. Immunol. 27:200.
67. Zatz, M. M., A. L. Golstein, and A. White. 1973. Lymphocyte populations of AKR-J mice. I. Effect of aging on migration patterns, response to PHA and expression of θ antigen. J. Immunol. 111:1514.
68. Zatz, M. M., B. C. Mellors, and E. M. Lance. 1971. Changes in lymphoid populations of ageing CBA and NZB mice. Clin. Exp. Immunol. 8:491.
69. Anokhin, I., A. A. Iarilin, and T. A. Norets. 1980. Age-related changes in splenic lymphocyte migration in mice. Ontogenez. 11:511. Russian.
70. Loetscher, P., M. Uguccioni, L. Bordoli, M. Baggiolini, B. Moser, C. Chizzolini, and J. M. Dayer. 1998. CCR5 is characteristic of Th1 lymphocytes. Nature 391: 344.
71. Bonecchi, R., G. Bianchi, P. B. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187:129.
72. Kim, C. H., E. J. Kunkel, J. Boisvert, B. Johnson, J. J. Campbell, M. C. Genovese, H. B. Greenberg, and E. C. Butcher. 2001. Bonzo/CXCR6 expression defines type 1-polarized T cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107:595.
73. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005.
74. Imai, T., M. Nagira, S. Takagi, M. Kakizaki, M. Nishimura, J. Wang, P. W. Gray, K. Matsushima, and O. Yoshi. 1999. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int. Immunol. 11:81.
75. Zingoni, A., H. Soto, J. A. Hedrick, A. Stoppacciaro, C. T. Storlazzi, F. Sinigaglia, D. D'Ambrosio, A. O'Garra, D. Robinson, M. Rocchi, et al. 1998. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J. Immunol. 161:547.
76. + T lymphocytes with regulatory activity. J. Immunol. 166: 996.
77. Nakajima, C., T. Mukai, N. Yamaguchi, Y. Morimoto, W. R. Park, M, Iwasaki, P. Gao, S. Ono, H. Fujiwara, and T. Hamaoka. 2002. Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: Dependence on the release from persistent TCR-triggering and requirement for IFN-γ stimulation. Eur. J. Immunol. 32:1792.
78. Iwasaki, M., T. Mukai, C. Nakajima, Y. F. Yang, P. Gao, N. Yamaguchi, M. Tomura, H. Fujiwara, and T. Hamaoka. 2001. A mandatory role for STAT4 in IL-12 induction of mouse T cell CCR5. J. Immunol. 167:6877.
79. Kim, C. H., L. Rott, E. J. Kunkel, M. C. Genovese, D. P. Andrew, L. Wu, and E. C. Butcher. 2001, Rules of chemokine receptor association with T cell polarization in vivo. J. Clin. Invest. 108:1331.
80. Centers for Disease Control and Prevention. 1998. AIDS among persons aged >50 years-United States, 1991-1996. Morbid. Mortal. Wkly. Rep. 47:21.
81. Wooten-Bielski, K. 1999. HIV and AIDS in older adults. Geriatr. Nurs. 20:268.
82. Szirony, T. A. 1999. Infection with HIV in the elderly. J. Gerontol. Nurs. 25:25.
83. Skiest, D., E. Rubenstein, N. Carley, L. Giorella, and R. Lyons. 1996. The importance of comorbidity in HIV-infected patients over 55: A retrospective case control study. Am. J. Med. 101:605.
84. Bleul, C. C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, J. Sodroski, and T. A. Springer. 1996. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382:829.
85. Reynes, J., P. Portales, M. Segondy, V. Baillat, P. André, O. Avinens, M. C. Picot, J. Clot, J. F. Eliaou, and P. Corbeau. 2001. CD4 T cell surface CCR5 density as a host factor in HIV-1 disease progression. AIDS 15:1627.
86. Lawrence, R. C., M. C. Hochberg, J. L. Kelsey, F. C. McDuffie, T. A. Medsger, W. R. Felts, and L. E. Shulman. 1989. Estimates of the prevalence of selected arthritic and musculoskeletal diseases in the United States. J. Rheumatol. 16:427.
87. Linos, A., J. W. Worthington, W. M. O'Fallon, and L. T. Kurland. 1980. The epidemiology of rheumatoid arthritis in Rochester, Minnesota: A study of incidence, prevalence, and mortality. Am. J. Epidemiol. 111:87.
88. Symmons, D. P., E. M. Barrett, C. R. Bankhead, D. G. Scott, and A. J. Silman. 1994. The occurrence of rheumatoid arthritis in the United Kingdom: Results from the Norfolk arthritis register. Br. J. Rheumatol. 33:735.
89. Katschke, K. J., J. B. Rottman, J. H. Ruth, S. Qin, L. Wu, G. LaRosa, P. Ponath, C. C. Park, R. M. Pope, and A. E. Koch. 2001. Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis. Arthritis Rheum. 44:1022.
90. Mach, F., A. Sauty, A. S. Iarossi, G. K. Sukhova, K. Neote, P. Libby, and A. D. Luster. 1999. Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells. J. Clin. Invest. 104:1041.
91. Frostegard, J., A. K. Ulfgren, P. Nyberg, U. Hedin, J. Swedenborg, U. Andersson, and G. K. Hansson. 1999. Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 145:33.
92. Reape, T. J., and P. H. E. Groot, 1999. Chemokines and atherosclerosis. Atherosclerosis 147:213.
93. Daugherty, A., and D. L. Rateri. 2002. T lymphocytes in atherosclerosis: The yin-yang of Th1 and Th2 influence on lesion formation. Circ. Res. 90:1039.
94. Eisen, M. B., P. T. Spellman, P. O. Brown, and D. Botstein. 1998. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95:14863.