The heat shock transcription factor Hsf1 is downregulated in DNA damage-associated senescence, contributing to the maintenance of senescence phenotype

Aging Cell

Volumn 11, Issue 4, 2012, Pages 617-627

  Kim, Geunwon ^a   Meriin, Anatoli B ^a   Gabai, Vladimir L ^a   Christians, Elisabeth ^b   Benjamin, Ivor ^c   Wilson, Andrew ^a   Wolozin, Benjamin ^a   Sherman, Michael Y ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Heat shock response; Hsp70; HuR; Inflammation; P38; P53; SIRT1

Indexed keywords

HEAT SHOCK TRANSCRIPTION FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P21; SIRTUIN 1; SYNAPTOPHYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; FIBROBLAST; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; SENESCENCE; SIGNAL TRANSDUCTION; WERNER SYNDROME;

CELL AGING; CELL LINE; DNA DAMAGE; DNA-BINDING PROTEINS; DOWN-REGULATION; FEEDBACK, PHYSIOLOGICAL; FIBROBLASTS; HEAT-SHOCK RESPONSE; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; SIRTUIN 1; TRANSCRIPTION FACTORS; WERNER SYNDROME;

EID: 84863992349     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2012.00827.x     Document Type: Article

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