Alteration of familial ALS-linked mutant SOD1 solubility with disease progression: Its modulation by the proteasome and Hsp70

Biochemical and Biophysical Research Communications

Volumn 343, Issue 3, 2006, Pages 719-730

  Koyama, Shingo ^a   Arawaka, Shigeki ^a   Chang Hong, Ren ^a   Wada, Manabu ^a   Kawanami, Toru ^a   Kurita, Keiji ^a   Kato, Masaaki ^b   Nagai, Makiko ^b   Aoki, Masashi ^b   Itoyama, Yasuto ^b   Sobue, Gen ^c   Chan, Pak H ^d   Kato, Takeo ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyotrophic lateral sclerosis; Cu Zn superoxide dismutase; Heat shock protein; Oligomer; Proteasome

Indexed keywords

CHAPERONE; COPPER ZINC SUPEROXIDE DISMUTASE; DODECYL SULFATE SODIUM; FORMIC ACID; HEAT SHOCK PROTEIN 70; MONOMER; MUTANT PROTEIN; PROTEASOME; PROTEASOME INHIBITOR; TRITON X 100;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN COS7; CONCENTRATION (PARAMETERS); DISEASE COURSE; MOLECULAR WEIGHT; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; SPECIES IDENTIFICATION; SPINAL CORD; TRANSGENIC MOUSE;

AGE FACTORS; AGING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE PROGRESSION; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; SODIUM DODECYL SULFATE; SOLUBILITY; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 33645897980     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.02.170     Document Type: Article

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